Consumption of uncooked deer meat as a risk factor for hepatitis E virus infection: An age- and sex-matched case-control study

[Guest guest]

J Med Virol. 2004 Sep;74(1):67-70.

Consumption of uncooked deer meat as a risk factor for hepatitis E virus

infection: An age- and sex-matched case-control study.

Tei S, Kitajima N, Ohara S, Inoue Y, Miki M, Yamatani T, Yamabe H, Mishiro

S, Kinoshita Y.

Department of Internal Medicine, Kasai City Hospital, Hyogo, Japan.

It was reported previously food-borne transmission of hepatitis E virus

(HEV) to humans from deer meat. The present study attempted to clarify

whether eating uncooked deer meat is a major epidemiological risk factor for

HEV infection in Kasai, a city in western Japan. In total, 45 volunteer

subjects with experience of eating raw deer meat were enrolled. An

equivalent number of people from the same area who had never eaten raw deer

meat served as controls. The subjects and controls had comparable age and

sex distributions. Serum anti-HEV IgG and anti-hepatitis A virus (HAV) IgG

levels were measured in all 90 volunteers. There was no significant

difference in age, overseas travel history, or rate of anti-HAV antibody

positivity between the subjects and controls. Eight (17.7%) of the subjects

but only one (2.2%) of the controls had measurable serum anti-HEV IgG levels

(P = 0.014). Anti-HAV prevalence did not differ between the

anti-HEV-positive and negative groups. The results suggest that eating

uncooked deer meat is an epidemiological risk factor for HEV infection in

the studied area. In countries such as Japan where deer meat is sometimes

eaten raw, attention must be paid to this route of HEV infection. J. Med.

Virol. 74:67-70, 2004. Copyright 2004 Wiley-Liss, Inc.

PMID: 15258970 [PubMed - in process]

[Guest guest]

J Med Virol. 2004 Sep;74(1):67-70.

Consumption of uncooked deer meat as a risk factor for hepatitis E virus

infection: An age- and sex-matched case-control study.

Tei S, Kitajima N, Ohara S, Inoue Y, Miki M, Yamatani T, Yamabe H, Mishiro

S, Kinoshita Y.

Department of Internal Medicine, Kasai City Hospital, Hyogo, Japan.

It was reported previously food-borne transmission of hepatitis E virus

(HEV) to humans from deer meat. The present study attempted to clarify

whether eating uncooked deer meat is a major epidemiological risk factor for

HEV infection in Kasai, a city in western Japan. In total, 45 volunteer

subjects with experience of eating raw deer meat were enrolled. An

equivalent number of people from the same area who had never eaten raw deer

meat served as controls. The subjects and controls had comparable age and

sex distributions. Serum anti-HEV IgG and anti-hepatitis A virus (HAV) IgG

levels were measured in all 90 volunteers. There was no significant

difference in age, overseas travel history, or rate of anti-HAV antibody

positivity between the subjects and controls. Eight (17.7%) of the subjects

but only one (2.2%) of the controls had measurable serum anti-HEV IgG levels

(P = 0.014). Anti-HAV prevalence did not differ between the

anti-HEV-positive and negative groups. The results suggest that eating

uncooked deer meat is an epidemiological risk factor for HEV infection in

the studied area. In countries such as Japan where deer meat is sometimes

eaten raw, attention must be paid to this route of HEV infection. J. Med.

Virol. 74:67-70, 2004. Copyright 2004 Wiley-Liss, Inc.

PMID: 15258970 [PubMed - in process]

[Guest guest]

J Med Virol. 2004 Sep;74(1):67-70.

Consumption of uncooked deer meat as a risk factor for hepatitis E virus

infection: An age- and sex-matched case-control study.

Tei S, Kitajima N, Ohara S, Inoue Y, Miki M, Yamatani T, Yamabe H, Mishiro

S, Kinoshita Y.

Department of Internal Medicine, Kasai City Hospital, Hyogo, Japan.

It was reported previously food-borne transmission of hepatitis E virus

(HEV) to humans from deer meat. The present study attempted to clarify

whether eating uncooked deer meat is a major epidemiological risk factor for

HEV infection in Kasai, a city in western Japan. In total, 45 volunteer

subjects with experience of eating raw deer meat were enrolled. An

equivalent number of people from the same area who had never eaten raw deer

meat served as controls. The subjects and controls had comparable age and

sex distributions. Serum anti-HEV IgG and anti-hepatitis A virus (HAV) IgG

levels were measured in all 90 volunteers. There was no significant

difference in age, overseas travel history, or rate of anti-HAV antibody

positivity between the subjects and controls. Eight (17.7%) of the subjects

but only one (2.2%) of the controls had measurable serum anti-HEV IgG levels

(P = 0.014). Anti-HAV prevalence did not differ between the

anti-HEV-positive and negative groups. The results suggest that eating

uncooked deer meat is an epidemiological risk factor for HEV infection in

the studied area. In countries such as Japan where deer meat is sometimes

eaten raw, attention must be paid to this route of HEV infection. J. Med.

Virol. 74:67-70, 2004. Copyright 2004 Wiley-Liss, Inc.

PMID: 15258970 [PubMed - in process]

[Guest guest]

J Med Virol. 2004 Sep;74(1):67-70.

Consumption of uncooked deer meat as a risk factor for hepatitis E virus

infection: An age- and sex-matched case-control study.

Tei S, Kitajima N, Ohara S, Inoue Y, Miki M, Yamatani T, Yamabe H, Mishiro

S, Kinoshita Y.

Department of Internal Medicine, Kasai City Hospital, Hyogo, Japan.

It was reported previously food-borne transmission of hepatitis E virus

(HEV) to humans from deer meat. The present study attempted to clarify

whether eating uncooked deer meat is a major epidemiological risk factor for

HEV infection in Kasai, a city in western Japan. In total, 45 volunteer

subjects with experience of eating raw deer meat were enrolled. An

equivalent number of people from the same area who had never eaten raw deer

meat served as controls. The subjects and controls had comparable age and

sex distributions. Serum anti-HEV IgG and anti-hepatitis A virus (HAV) IgG

levels were measured in all 90 volunteers. There was no significant

difference in age, overseas travel history, or rate of anti-HAV antibody

positivity between the subjects and controls. Eight (17.7%) of the subjects

but only one (2.2%) of the controls had measurable serum anti-HEV IgG levels

(P = 0.014). Anti-HAV prevalence did not differ between the

anti-HEV-positive and negative groups. The results suggest that eating

uncooked deer meat is an epidemiological risk factor for HEV infection in

the studied area. In countries such as Japan where deer meat is sometimes

eaten raw, attention must be paid to this route of HEV infection. J. Med.

Virol. 74:67-70, 2004. Copyright 2004 Wiley-Liss, Inc.

PMID: 15258970 [PubMed - in process]