Impact of Adult Living Donor Liver Transplantation on Waiting Time Survival in Candidates Listed for Liver Transplantation

[Guest guest]

American Journal of Transplantation

Volume 4 Issue 3 Page 427 - March 2004

doi:10.1111/j.1600-6143.2004.00336.x

Impact of Adult Living Donor Liver Transplantation on Waiting Time Survival

in Candidates Listed for Liver Transplantation

Mark W. Russoa,*, Dianne LaPointe-Rudowb, Milan Kinkhabwalab, Emondb

and S. Brown Jrb

Studies comparing adult living donor liver transplantation to deceased donor

liver transplantation have focused on post-transplant survival. Our aim was

to focus on the impact of living donor liver transplant on waiting time

mortality and overall mortality. We analyzed the affect of living donor

liver transplantation on waiting time mortality and overall mortality (from

listing until last follow up) in a cohort of 116 transplant candidates.

Fifty-eight candidates who had individuals present as potential living

donors (volunteer group) were matched by MELD score to 58 liver transplant

candidates who did not have individuals present as a potential living donor

(no volunteer group). Twenty-seven percent of candidates in the no volunteer

group and 62% of candidates in the volunteer group underwent liver

transplantation, p = 0.0003. One-year waiting list mortality for the

volunteer group and no volunteer group was 10% and 20%, respectively, p =

0.03. Patient survival from the time of listing to last follow up was

similar between the two groups. In our study group, living donor liver

transplantation is associated with a higher rate of liver transplantation

and lower waiting time mortality. In the era of living donor liver

transplantation, estimates of patient survival should incorporate waiting

time mortality.

[Guest guest]

American Journal of Transplantation

Volume 4 Issue 3 Page 427 - March 2004

doi:10.1111/j.1600-6143.2004.00336.x

Impact of Adult Living Donor Liver Transplantation on Waiting Time Survival

in Candidates Listed for Liver Transplantation

Mark W. Russoa,*, Dianne LaPointe-Rudowb, Milan Kinkhabwalab, Emondb

and S. Brown Jrb

Studies comparing adult living donor liver transplantation to deceased donor

liver transplantation have focused on post-transplant survival. Our aim was

to focus on the impact of living donor liver transplant on waiting time

mortality and overall mortality. We analyzed the affect of living donor

liver transplantation on waiting time mortality and overall mortality (from

listing until last follow up) in a cohort of 116 transplant candidates.

Fifty-eight candidates who had individuals present as potential living

donors (volunteer group) were matched by MELD score to 58 liver transplant

candidates who did not have individuals present as a potential living donor

(no volunteer group). Twenty-seven percent of candidates in the no volunteer

group and 62% of candidates in the volunteer group underwent liver

transplantation, p = 0.0003. One-year waiting list mortality for the

volunteer group and no volunteer group was 10% and 20%, respectively, p =

0.03. Patient survival from the time of listing to last follow up was

similar between the two groups. In our study group, living donor liver

transplantation is associated with a higher rate of liver transplantation

and lower waiting time mortality. In the era of living donor liver

transplantation, estimates of patient survival should incorporate waiting

time mortality.

[Guest guest]

American Journal of Transplantation

Volume 4 Issue 3 Page 427 - March 2004

doi:10.1111/j.1600-6143.2004.00336.x

Impact of Adult Living Donor Liver Transplantation on Waiting Time Survival

in Candidates Listed for Liver Transplantation

Mark W. Russoa,*, Dianne LaPointe-Rudowb, Milan Kinkhabwalab, Emondb

and S. Brown Jrb

Studies comparing adult living donor liver transplantation to deceased donor

liver transplantation have focused on post-transplant survival. Our aim was

to focus on the impact of living donor liver transplant on waiting time

mortality and overall mortality. We analyzed the affect of living donor

liver transplantation on waiting time mortality and overall mortality (from

listing until last follow up) in a cohort of 116 transplant candidates.

Fifty-eight candidates who had individuals present as potential living

donors (volunteer group) were matched by MELD score to 58 liver transplant

candidates who did not have individuals present as a potential living donor

(no volunteer group). Twenty-seven percent of candidates in the no volunteer

group and 62% of candidates in the volunteer group underwent liver

transplantation, p = 0.0003. One-year waiting list mortality for the

volunteer group and no volunteer group was 10% and 20%, respectively, p =

0.03. Patient survival from the time of listing to last follow up was

similar between the two groups. In our study group, living donor liver

transplantation is associated with a higher rate of liver transplantation

and lower waiting time mortality. In the era of living donor liver

transplantation, estimates of patient survival should incorporate waiting

time mortality.

[Guest guest]

American Journal of Transplantation

Volume 4 Issue 3 Page 427 - March 2004

doi:10.1111/j.1600-6143.2004.00336.x

Impact of Adult Living Donor Liver Transplantation on Waiting Time Survival

in Candidates Listed for Liver Transplantation

Mark W. Russoa,*, Dianne LaPointe-Rudowb, Milan Kinkhabwalab, Emondb

and S. Brown Jrb

Studies comparing adult living donor liver transplantation to deceased donor

liver transplantation have focused on post-transplant survival. Our aim was

to focus on the impact of living donor liver transplant on waiting time

mortality and overall mortality. We analyzed the affect of living donor

liver transplantation on waiting time mortality and overall mortality (from

listing until last follow up) in a cohort of 116 transplant candidates.

Fifty-eight candidates who had individuals present as potential living

donors (volunteer group) were matched by MELD score to 58 liver transplant

candidates who did not have individuals present as a potential living donor

(no volunteer group). Twenty-seven percent of candidates in the no volunteer

group and 62% of candidates in the volunteer group underwent liver

transplantation, p = 0.0003. One-year waiting list mortality for the

volunteer group and no volunteer group was 10% and 20%, respectively, p =

0.03. Patient survival from the time of listing to last follow up was

similar between the two groups. In our study group, living donor liver

transplantation is associated with a higher rate of liver transplantation

and lower waiting time mortality. In the era of living donor liver

transplantation, estimates of patient survival should incorporate waiting

time mortality.