Depakote during pregnancy...

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http://story.news./news?tmpl=story & cid=97 & ncid=751 & e=9 & u=/hsn/20041014/\

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Epilepsy Drug Linked to Developmental Delays in Offspring

17 minutes ago Health - HealthDay

THURSDAY, Oct. 14 (HealthDayNews) -- The epilepsy drug sodium valproate has

been linked to children born with developmental delays and lower IQs, says

research published in the current issue of the Journal of Neurology,

Neurosurgery and Psychiatry.

The study focused on 375 children born to mothers with confirmed epilepsy in

Liverpool and Manchester in northwest England.

All but 80 of the children had been exposed to epilepsy drugs while in the

womb. In 41 cases, the drug was sodium valproate.

Researchers found that children whose mothers had taken sodium valproate

alone had an IQ in the low-average range, an average of seven points lower

than would have been expected, wrote lead author Chadwick of the

Walton Centre for Neurology and Neurosurgery in Liverpool.

A verbal IQ score of 69 or lower was more than three times likely in

children exposed to sodium valproate alone, compared with children whose

mothers had not taken any epileptic drugs.

Anatomical abnormalities also were more common among children exposed to

sodium valproate in the womb, affecting 44 percent of children compared with

9 percent of those exposed to the epilepsy drug carbamazepine, and 2 percent

among those whose mothers took no drugs at all.

The research followed up on a 2000 British study that tentatively linked

epileptic drugs taken by mothers to developmental delays in their children.

That study found that mothers taking sodium valproate in combination with

other drugs were 2.5 times more likely to have a child with developmental

delays. If they were taking sodium valproate alone, that risk rose to 3.4

times.

[Guest guest]

http://story.news./news?tmpl=story & cid=97 & ncid=751 & e=9 & u=/hsn/20041014/\

hl_hsn/epilepsydruglinkedtodevelopmentaldelaysinoffspring

Epilepsy Drug Linked to Developmental Delays in Offspring

17 minutes ago Health - HealthDay

THURSDAY, Oct. 14 (HealthDayNews) -- The epilepsy drug sodium valproate has

been linked to children born with developmental delays and lower IQs, says

research published in the current issue of the Journal of Neurology,

Neurosurgery and Psychiatry.

The study focused on 375 children born to mothers with confirmed epilepsy in

Liverpool and Manchester in northwest England.

All but 80 of the children had been exposed to epilepsy drugs while in the

womb. In 41 cases, the drug was sodium valproate.

Researchers found that children whose mothers had taken sodium valproate

alone had an IQ in the low-average range, an average of seven points lower

than would have been expected, wrote lead author Chadwick of the

Walton Centre for Neurology and Neurosurgery in Liverpool.

A verbal IQ score of 69 or lower was more than three times likely in

children exposed to sodium valproate alone, compared with children whose

mothers had not taken any epileptic drugs.

Anatomical abnormalities also were more common among children exposed to

sodium valproate in the womb, affecting 44 percent of children compared with

9 percent of those exposed to the epilepsy drug carbamazepine, and 2 percent

among those whose mothers took no drugs at all.

The research followed up on a 2000 British study that tentatively linked

epileptic drugs taken by mothers to developmental delays in their children.

That study found that mothers taking sodium valproate in combination with

other drugs were 2.5 times more likely to have a child with developmental

delays. If they were taking sodium valproate alone, that risk rose to 3.4

times.

[Guest guest]

http://story.news./news?tmpl=story & cid=97 & ncid=751 & e=9 & u=/hsn/20041014/\

hl_hsn/epilepsydruglinkedtodevelopmentaldelaysinoffspring

Epilepsy Drug Linked to Developmental Delays in Offspring

17 minutes ago Health - HealthDay

THURSDAY, Oct. 14 (HealthDayNews) -- The epilepsy drug sodium valproate has

been linked to children born with developmental delays and lower IQs, says

research published in the current issue of the Journal of Neurology,

Neurosurgery and Psychiatry.

The study focused on 375 children born to mothers with confirmed epilepsy in

Liverpool and Manchester in northwest England.

All but 80 of the children had been exposed to epilepsy drugs while in the

womb. In 41 cases, the drug was sodium valproate.

Researchers found that children whose mothers had taken sodium valproate

alone had an IQ in the low-average range, an average of seven points lower

than would have been expected, wrote lead author Chadwick of the

Walton Centre for Neurology and Neurosurgery in Liverpool.

A verbal IQ score of 69 or lower was more than three times likely in

children exposed to sodium valproate alone, compared with children whose

mothers had not taken any epileptic drugs.

Anatomical abnormalities also were more common among children exposed to

sodium valproate in the womb, affecting 44 percent of children compared with

9 percent of those exposed to the epilepsy drug carbamazepine, and 2 percent

among those whose mothers took no drugs at all.

The research followed up on a 2000 British study that tentatively linked

epileptic drugs taken by mothers to developmental delays in their children.

That study found that mothers taking sodium valproate in combination with

other drugs were 2.5 times more likely to have a child with developmental

delays. If they were taking sodium valproate alone, that risk rose to 3.4

times.

[Guest guest]

http://story.news./news?tmpl=story & cid=97 & ncid=751 & e=9 & u=/hsn/20041014/\

hl_hsn/epilepsydruglinkedtodevelopmentaldelaysinoffspring

Epilepsy Drug Linked to Developmental Delays in Offspring

17 minutes ago Health - HealthDay

THURSDAY, Oct. 14 (HealthDayNews) -- The epilepsy drug sodium valproate has

been linked to children born with developmental delays and lower IQs, says

research published in the current issue of the Journal of Neurology,

Neurosurgery and Psychiatry.

The study focused on 375 children born to mothers with confirmed epilepsy in

Liverpool and Manchester in northwest England.

All but 80 of the children had been exposed to epilepsy drugs while in the

womb. In 41 cases, the drug was sodium valproate.

Researchers found that children whose mothers had taken sodium valproate

alone had an IQ in the low-average range, an average of seven points lower

than would have been expected, wrote lead author Chadwick of the

Walton Centre for Neurology and Neurosurgery in Liverpool.

A verbal IQ score of 69 or lower was more than three times likely in

children exposed to sodium valproate alone, compared with children whose

mothers had not taken any epileptic drugs.

Anatomical abnormalities also were more common among children exposed to

sodium valproate in the womb, affecting 44 percent of children compared with

9 percent of those exposed to the epilepsy drug carbamazepine, and 2 percent

among those whose mothers took no drugs at all.

The research followed up on a 2000 British study that tentatively linked

epileptic drugs taken by mothers to developmental delays in their children.

That study found that mothers taking sodium valproate in combination with

other drugs were 2.5 times more likely to have a child with developmental

delays. If they were taking sodium valproate alone, that risk rose to 3.4

times.