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http://www.washingtonpost.com/wp-dyn/articles/A13691-2004Dec20.html

Rx: Read This

Comparison Shop for Pills? A New Tool Lets You. But Experts Say Don't Buy on

Price Alone

By Ault

Special to The Washington Post

Tuesday, December 21, 2004; Page HE01

Most people wouldn't consider a major purchase without first comparing price

and reliability of the products in question. But that task has been next to

impossible for consumers of prescription drugs. This has been particularly

painful for the 45 million Americans who are uninsured at some point during

the year and the 25 million who are insured but have modest or no drug

coverage.

But now the standard bearer of comparison shopping -- Consumer Reports,

published by the nonprofit Consumers Union -- has launched a free service

that reports on the safety, effectiveness and cost of drugs. In each

category of medication, Consumer Reports even flags " best buys " -- the drugs

it considers to offer the safest and most effective therapy for the money.

This means, for instance, that people who need a cholesterol-lowering statin

drug can go to www.crbestbuydrugs.org and scan the options. Charts and text

explain how much cholesterol reduction to expect from each drug, whether it

has been proven to cut the risk of heart attack or death, the average

monthly cost and safety concerns.

Consumer Reports did not test each drug, as they might toasters or vacuum

cleaners. The ratings are based on independent analyses of published

clinical trials conducted by the Drug Effectiveness Review Project, a

venture funded by 12 states that's based at Oregon Health & Science

University.

The statin report, along with reports on proton pump inhibitors (for acid

reflux, heartburn and ulcers) and on nonsteroidal anti-inflammatory drugs

(for arthritis and pain) now appear online. Consumers Union plans to add one

new class of drugs per month over the next year. Some partner groups,

including Families USA, U.S. Public Interest Research Group and the AFL-CIO

hope to distribute print versions of the data. Due next: Reports on

selective serotonin reuptake inhibitor (SSRI) antidepressants (such as

Prozac and Paxil) and two categories of heart drugs, ACE inhibitors and beta

blockers.

The Consumers Union Best Buy program is part of a burgeoning industry aimed

at empowering drug purchasers to make better-informed and

more-cost-effective choices. A number of Web sites, including

www.pdrhealth.com, www.safemedication.com, www.webmd.com and

www.intellihealth.com, offer information on drug dosing, side effects,

contraindications and Food and Drug Administration (FDA) actions. And it's

possible to track down a drug's approximate retail cost by calling local

pharmacies or checking prices on www.drugstore.com or other online

pharmacies. Early next year, AARP will launch a Web site listing drug

effectiveness data and some price information, said Van Ellet, AARP senior

legislative representative. For now, the Consumers Union's Web site appears

to be unique in offering cost, safety and effectiveness information in one

place. The price data reflect national averages compiled by NDCHealth, a

subscription-only service, and should be used only as a rough guide, said

Gail Shearer, director of health policy analysis for Consumers Union. " It is

important for people to understand that some shopping around could really

benefit them, " she said.

The group thinks that by shining a spotlight on cost and effectiveness, drug

makers will be pressured to cut prices, especially on less-effective

medications, said Shearer.

The site explicitly warns people not to self-treat or change their

medications without consulting their doctors. The group regards its reports

as something " that consumers can take to their doctors to talk with them

about their drug treatment choices, " said Joe Gurin, executive vice

president of Consumers Union.

The drug industry and some physicians said the reports emphasize cost over

individual needs and that steering consumers in some cases to

over-the-counter (OTC) medicines could result in dangerous self-treatment.

For instance, Consumers Union flags the OTC drug Prilosec as its " best buy "

for acid reflux and heartburn, saying it works just as well as the

top-selling brand, Nexium (esomeprazole), ubiquitously marketed as the

" Purple Pill. " The site reports that OTC Prilosec costs $24 a month,

compared to about $170 a month for Nexium.

" There clearly is a place for Prilosec OTC, but it's not for everyone, " said

Jim Coyne, a spokesman for Nexium's maker, AstraZeneca. " You can't lose

sight of the fact that acid reflux disease is not something that people

should be self-treating. "

Cost is not always the reports' main consideration. For statins, the " best

buy " for people who need to cut cholesterol by more than 40 percent is

Lipitor, the top-seller in the class and among the most expensive pills at

$117 a month.

For arthritis and other pain, the " best buy " is prescription generic

ibuprofen, at less than $30 a month. Top-selling COX-2 inhibitors like

Celebrex (celecoxib) should only be considered, the report states, if

someone has a high risk of stomach bleeding or low risk of heart attack or

stroke. Consumers Union cautions against the COX-2s, noting that Merck's

drug in the class, Vioxx (rofecoxib) was recently withdrawn because it

increased risk of heart attack and stroke.

Borenstein, a rheumatologist in private practice in Washington, said

the rating report is scientifically accurate but has been made " a bit

simplistic for the general public. " OTC painkillers and prescription

ibuprofen work fine for people with short-term aches and pains, he said, but

for patients with long-term arthritis pain, more-powerful drugs are usually

needed, as well as a physician-mediated assessment of those drugs' risks and

benefits.

" If you've had GI troubles or heart troubles, this is something where you're

not going to go just to OTC medications. You're going to want to talk to

your doctor about which would be the best agents, " he said.

Sidney Wolfe, director of Public Citizen's Health Research Group, agreed

that consumers should be wary about making a choice based on price alone.

The Consumers Union's ratings are useful, he said, " but if it turns out that

a drug is particularly dangerous, even though it may cost less, that's not

the kind of advice that is in and of itself a good idea. "

Wolfe's nonprofit advocacy group often petitions the FDA to withdraw drugs

it believes are unsafe, and highlights those products, now numbering 181, on

its Web site, www.worstpills.org. That service, which costs $15 per year,

lists alternatives to those drugs and sends out alerts when new safety

information becomes available.

Consumers Union's Web-based reports will be updated when new effectiveness,

safety, or cost data appear, Shearer said. Some of those updates will come

from the Drug Effectiveness Review Project, but Consumers Union will also

closely monitor safety and price changes, she said.•

Link to comment
Share on other sites

http://www.washingtonpost.com/wp-dyn/articles/A13691-2004Dec20.html

Rx: Read This

Comparison Shop for Pills? A New Tool Lets You. But Experts Say Don't Buy on

Price Alone

By Ault

Special to The Washington Post

Tuesday, December 21, 2004; Page HE01

Most people wouldn't consider a major purchase without first comparing price

and reliability of the products in question. But that task has been next to

impossible for consumers of prescription drugs. This has been particularly

painful for the 45 million Americans who are uninsured at some point during

the year and the 25 million who are insured but have modest or no drug

coverage.

But now the standard bearer of comparison shopping -- Consumer Reports,

published by the nonprofit Consumers Union -- has launched a free service

that reports on the safety, effectiveness and cost of drugs. In each

category of medication, Consumer Reports even flags " best buys " -- the drugs

it considers to offer the safest and most effective therapy for the money.

This means, for instance, that people who need a cholesterol-lowering statin

drug can go to www.crbestbuydrugs.org and scan the options. Charts and text

explain how much cholesterol reduction to expect from each drug, whether it

has been proven to cut the risk of heart attack or death, the average

monthly cost and safety concerns.

Consumer Reports did not test each drug, as they might toasters or vacuum

cleaners. The ratings are based on independent analyses of published

clinical trials conducted by the Drug Effectiveness Review Project, a

venture funded by 12 states that's based at Oregon Health & Science

University.

The statin report, along with reports on proton pump inhibitors (for acid

reflux, heartburn and ulcers) and on nonsteroidal anti-inflammatory drugs

(for arthritis and pain) now appear online. Consumers Union plans to add one

new class of drugs per month over the next year. Some partner groups,

including Families USA, U.S. Public Interest Research Group and the AFL-CIO

hope to distribute print versions of the data. Due next: Reports on

selective serotonin reuptake inhibitor (SSRI) antidepressants (such as

Prozac and Paxil) and two categories of heart drugs, ACE inhibitors and beta

blockers.

The Consumers Union Best Buy program is part of a burgeoning industry aimed

at empowering drug purchasers to make better-informed and

more-cost-effective choices. A number of Web sites, including

www.pdrhealth.com, www.safemedication.com, www.webmd.com and

www.intellihealth.com, offer information on drug dosing, side effects,

contraindications and Food and Drug Administration (FDA) actions. And it's

possible to track down a drug's approximate retail cost by calling local

pharmacies or checking prices on www.drugstore.com or other online

pharmacies. Early next year, AARP will launch a Web site listing drug

effectiveness data and some price information, said Van Ellet, AARP senior

legislative representative. For now, the Consumers Union's Web site appears

to be unique in offering cost, safety and effectiveness information in one

place. The price data reflect national averages compiled by NDCHealth, a

subscription-only service, and should be used only as a rough guide, said

Gail Shearer, director of health policy analysis for Consumers Union. " It is

important for people to understand that some shopping around could really

benefit them, " she said.

The group thinks that by shining a spotlight on cost and effectiveness, drug

makers will be pressured to cut prices, especially on less-effective

medications, said Shearer.

The site explicitly warns people not to self-treat or change their

medications without consulting their doctors. The group regards its reports

as something " that consumers can take to their doctors to talk with them

about their drug treatment choices, " said Joe Gurin, executive vice

president of Consumers Union.

The drug industry and some physicians said the reports emphasize cost over

individual needs and that steering consumers in some cases to

over-the-counter (OTC) medicines could result in dangerous self-treatment.

For instance, Consumers Union flags the OTC drug Prilosec as its " best buy "

for acid reflux and heartburn, saying it works just as well as the

top-selling brand, Nexium (esomeprazole), ubiquitously marketed as the

" Purple Pill. " The site reports that OTC Prilosec costs $24 a month,

compared to about $170 a month for Nexium.

" There clearly is a place for Prilosec OTC, but it's not for everyone, " said

Jim Coyne, a spokesman for Nexium's maker, AstraZeneca. " You can't lose

sight of the fact that acid reflux disease is not something that people

should be self-treating. "

Cost is not always the reports' main consideration. For statins, the " best

buy " for people who need to cut cholesterol by more than 40 percent is

Lipitor, the top-seller in the class and among the most expensive pills at

$117 a month.

For arthritis and other pain, the " best buy " is prescription generic

ibuprofen, at less than $30 a month. Top-selling COX-2 inhibitors like

Celebrex (celecoxib) should only be considered, the report states, if

someone has a high risk of stomach bleeding or low risk of heart attack or

stroke. Consumers Union cautions against the COX-2s, noting that Merck's

drug in the class, Vioxx (rofecoxib) was recently withdrawn because it

increased risk of heart attack and stroke.

Borenstein, a rheumatologist in private practice in Washington, said

the rating report is scientifically accurate but has been made " a bit

simplistic for the general public. " OTC painkillers and prescription

ibuprofen work fine for people with short-term aches and pains, he said, but

for patients with long-term arthritis pain, more-powerful drugs are usually

needed, as well as a physician-mediated assessment of those drugs' risks and

benefits.

" If you've had GI troubles or heart troubles, this is something where you're

not going to go just to OTC medications. You're going to want to talk to

your doctor about which would be the best agents, " he said.

Sidney Wolfe, director of Public Citizen's Health Research Group, agreed

that consumers should be wary about making a choice based on price alone.

The Consumers Union's ratings are useful, he said, " but if it turns out that

a drug is particularly dangerous, even though it may cost less, that's not

the kind of advice that is in and of itself a good idea. "

Wolfe's nonprofit advocacy group often petitions the FDA to withdraw drugs

it believes are unsafe, and highlights those products, now numbering 181, on

its Web site, www.worstpills.org. That service, which costs $15 per year,

lists alternatives to those drugs and sends out alerts when new safety

information becomes available.

Consumers Union's Web-based reports will be updated when new effectiveness,

safety, or cost data appear, Shearer said. Some of those updates will come

from the Drug Effectiveness Review Project, but Consumers Union will also

closely monitor safety and price changes, she said.•

Link to comment
Share on other sites

http://www.washingtonpost.com/wp-dyn/articles/A13691-2004Dec20.html

Rx: Read This

Comparison Shop for Pills? A New Tool Lets You. But Experts Say Don't Buy on

Price Alone

By Ault

Special to The Washington Post

Tuesday, December 21, 2004; Page HE01

Most people wouldn't consider a major purchase without first comparing price

and reliability of the products in question. But that task has been next to

impossible for consumers of prescription drugs. This has been particularly

painful for the 45 million Americans who are uninsured at some point during

the year and the 25 million who are insured but have modest or no drug

coverage.

But now the standard bearer of comparison shopping -- Consumer Reports,

published by the nonprofit Consumers Union -- has launched a free service

that reports on the safety, effectiveness and cost of drugs. In each

category of medication, Consumer Reports even flags " best buys " -- the drugs

it considers to offer the safest and most effective therapy for the money.

This means, for instance, that people who need a cholesterol-lowering statin

drug can go to www.crbestbuydrugs.org and scan the options. Charts and text

explain how much cholesterol reduction to expect from each drug, whether it

has been proven to cut the risk of heart attack or death, the average

monthly cost and safety concerns.

Consumer Reports did not test each drug, as they might toasters or vacuum

cleaners. The ratings are based on independent analyses of published

clinical trials conducted by the Drug Effectiveness Review Project, a

venture funded by 12 states that's based at Oregon Health & Science

University.

The statin report, along with reports on proton pump inhibitors (for acid

reflux, heartburn and ulcers) and on nonsteroidal anti-inflammatory drugs

(for arthritis and pain) now appear online. Consumers Union plans to add one

new class of drugs per month over the next year. Some partner groups,

including Families USA, U.S. Public Interest Research Group and the AFL-CIO

hope to distribute print versions of the data. Due next: Reports on

selective serotonin reuptake inhibitor (SSRI) antidepressants (such as

Prozac and Paxil) and two categories of heart drugs, ACE inhibitors and beta

blockers.

The Consumers Union Best Buy program is part of a burgeoning industry aimed

at empowering drug purchasers to make better-informed and

more-cost-effective choices. A number of Web sites, including

www.pdrhealth.com, www.safemedication.com, www.webmd.com and

www.intellihealth.com, offer information on drug dosing, side effects,

contraindications and Food and Drug Administration (FDA) actions. And it's

possible to track down a drug's approximate retail cost by calling local

pharmacies or checking prices on www.drugstore.com or other online

pharmacies. Early next year, AARP will launch a Web site listing drug

effectiveness data and some price information, said Van Ellet, AARP senior

legislative representative. For now, the Consumers Union's Web site appears

to be unique in offering cost, safety and effectiveness information in one

place. The price data reflect national averages compiled by NDCHealth, a

subscription-only service, and should be used only as a rough guide, said

Gail Shearer, director of health policy analysis for Consumers Union. " It is

important for people to understand that some shopping around could really

benefit them, " she said.

The group thinks that by shining a spotlight on cost and effectiveness, drug

makers will be pressured to cut prices, especially on less-effective

medications, said Shearer.

The site explicitly warns people not to self-treat or change their

medications without consulting their doctors. The group regards its reports

as something " that consumers can take to their doctors to talk with them

about their drug treatment choices, " said Joe Gurin, executive vice

president of Consumers Union.

The drug industry and some physicians said the reports emphasize cost over

individual needs and that steering consumers in some cases to

over-the-counter (OTC) medicines could result in dangerous self-treatment.

For instance, Consumers Union flags the OTC drug Prilosec as its " best buy "

for acid reflux and heartburn, saying it works just as well as the

top-selling brand, Nexium (esomeprazole), ubiquitously marketed as the

" Purple Pill. " The site reports that OTC Prilosec costs $24 a month,

compared to about $170 a month for Nexium.

" There clearly is a place for Prilosec OTC, but it's not for everyone, " said

Jim Coyne, a spokesman for Nexium's maker, AstraZeneca. " You can't lose

sight of the fact that acid reflux disease is not something that people

should be self-treating. "

Cost is not always the reports' main consideration. For statins, the " best

buy " for people who need to cut cholesterol by more than 40 percent is

Lipitor, the top-seller in the class and among the most expensive pills at

$117 a month.

For arthritis and other pain, the " best buy " is prescription generic

ibuprofen, at less than $30 a month. Top-selling COX-2 inhibitors like

Celebrex (celecoxib) should only be considered, the report states, if

someone has a high risk of stomach bleeding or low risk of heart attack or

stroke. Consumers Union cautions against the COX-2s, noting that Merck's

drug in the class, Vioxx (rofecoxib) was recently withdrawn because it

increased risk of heart attack and stroke.

Borenstein, a rheumatologist in private practice in Washington, said

the rating report is scientifically accurate but has been made " a bit

simplistic for the general public. " OTC painkillers and prescription

ibuprofen work fine for people with short-term aches and pains, he said, but

for patients with long-term arthritis pain, more-powerful drugs are usually

needed, as well as a physician-mediated assessment of those drugs' risks and

benefits.

" If you've had GI troubles or heart troubles, this is something where you're

not going to go just to OTC medications. You're going to want to talk to

your doctor about which would be the best agents, " he said.

Sidney Wolfe, director of Public Citizen's Health Research Group, agreed

that consumers should be wary about making a choice based on price alone.

The Consumers Union's ratings are useful, he said, " but if it turns out that

a drug is particularly dangerous, even though it may cost less, that's not

the kind of advice that is in and of itself a good idea. "

Wolfe's nonprofit advocacy group often petitions the FDA to withdraw drugs

it believes are unsafe, and highlights those products, now numbering 181, on

its Web site, www.worstpills.org. That service, which costs $15 per year,

lists alternatives to those drugs and sends out alerts when new safety

information becomes available.

Consumers Union's Web-based reports will be updated when new effectiveness,

safety, or cost data appear, Shearer said. Some of those updates will come

from the Drug Effectiveness Review Project, but Consumers Union will also

closely monitor safety and price changes, she said.•

Link to comment
Share on other sites

http://www.washingtonpost.com/wp-dyn/articles/A13691-2004Dec20.html

Rx: Read This

Comparison Shop for Pills? A New Tool Lets You. But Experts Say Don't Buy on

Price Alone

By Ault

Special to The Washington Post

Tuesday, December 21, 2004; Page HE01

Most people wouldn't consider a major purchase without first comparing price

and reliability of the products in question. But that task has been next to

impossible for consumers of prescription drugs. This has been particularly

painful for the 45 million Americans who are uninsured at some point during

the year and the 25 million who are insured but have modest or no drug

coverage.

But now the standard bearer of comparison shopping -- Consumer Reports,

published by the nonprofit Consumers Union -- has launched a free service

that reports on the safety, effectiveness and cost of drugs. In each

category of medication, Consumer Reports even flags " best buys " -- the drugs

it considers to offer the safest and most effective therapy for the money.

This means, for instance, that people who need a cholesterol-lowering statin

drug can go to www.crbestbuydrugs.org and scan the options. Charts and text

explain how much cholesterol reduction to expect from each drug, whether it

has been proven to cut the risk of heart attack or death, the average

monthly cost and safety concerns.

Consumer Reports did not test each drug, as they might toasters or vacuum

cleaners. The ratings are based on independent analyses of published

clinical trials conducted by the Drug Effectiveness Review Project, a

venture funded by 12 states that's based at Oregon Health & Science

University.

The statin report, along with reports on proton pump inhibitors (for acid

reflux, heartburn and ulcers) and on nonsteroidal anti-inflammatory drugs

(for arthritis and pain) now appear online. Consumers Union plans to add one

new class of drugs per month over the next year. Some partner groups,

including Families USA, U.S. Public Interest Research Group and the AFL-CIO

hope to distribute print versions of the data. Due next: Reports on

selective serotonin reuptake inhibitor (SSRI) antidepressants (such as

Prozac and Paxil) and two categories of heart drugs, ACE inhibitors and beta

blockers.

The Consumers Union Best Buy program is part of a burgeoning industry aimed

at empowering drug purchasers to make better-informed and

more-cost-effective choices. A number of Web sites, including

www.pdrhealth.com, www.safemedication.com, www.webmd.com and

www.intellihealth.com, offer information on drug dosing, side effects,

contraindications and Food and Drug Administration (FDA) actions. And it's

possible to track down a drug's approximate retail cost by calling local

pharmacies or checking prices on www.drugstore.com or other online

pharmacies. Early next year, AARP will launch a Web site listing drug

effectiveness data and some price information, said Van Ellet, AARP senior

legislative representative. For now, the Consumers Union's Web site appears

to be unique in offering cost, safety and effectiveness information in one

place. The price data reflect national averages compiled by NDCHealth, a

subscription-only service, and should be used only as a rough guide, said

Gail Shearer, director of health policy analysis for Consumers Union. " It is

important for people to understand that some shopping around could really

benefit them, " she said.

The group thinks that by shining a spotlight on cost and effectiveness, drug

makers will be pressured to cut prices, especially on less-effective

medications, said Shearer.

The site explicitly warns people not to self-treat or change their

medications without consulting their doctors. The group regards its reports

as something " that consumers can take to their doctors to talk with them

about their drug treatment choices, " said Joe Gurin, executive vice

president of Consumers Union.

The drug industry and some physicians said the reports emphasize cost over

individual needs and that steering consumers in some cases to

over-the-counter (OTC) medicines could result in dangerous self-treatment.

For instance, Consumers Union flags the OTC drug Prilosec as its " best buy "

for acid reflux and heartburn, saying it works just as well as the

top-selling brand, Nexium (esomeprazole), ubiquitously marketed as the

" Purple Pill. " The site reports that OTC Prilosec costs $24 a month,

compared to about $170 a month for Nexium.

" There clearly is a place for Prilosec OTC, but it's not for everyone, " said

Jim Coyne, a spokesman for Nexium's maker, AstraZeneca. " You can't lose

sight of the fact that acid reflux disease is not something that people

should be self-treating. "

Cost is not always the reports' main consideration. For statins, the " best

buy " for people who need to cut cholesterol by more than 40 percent is

Lipitor, the top-seller in the class and among the most expensive pills at

$117 a month.

For arthritis and other pain, the " best buy " is prescription generic

ibuprofen, at less than $30 a month. Top-selling COX-2 inhibitors like

Celebrex (celecoxib) should only be considered, the report states, if

someone has a high risk of stomach bleeding or low risk of heart attack or

stroke. Consumers Union cautions against the COX-2s, noting that Merck's

drug in the class, Vioxx (rofecoxib) was recently withdrawn because it

increased risk of heart attack and stroke.

Borenstein, a rheumatologist in private practice in Washington, said

the rating report is scientifically accurate but has been made " a bit

simplistic for the general public. " OTC painkillers and prescription

ibuprofen work fine for people with short-term aches and pains, he said, but

for patients with long-term arthritis pain, more-powerful drugs are usually

needed, as well as a physician-mediated assessment of those drugs' risks and

benefits.

" If you've had GI troubles or heart troubles, this is something where you're

not going to go just to OTC medications. You're going to want to talk to

your doctor about which would be the best agents, " he said.

Sidney Wolfe, director of Public Citizen's Health Research Group, agreed

that consumers should be wary about making a choice based on price alone.

The Consumers Union's ratings are useful, he said, " but if it turns out that

a drug is particularly dangerous, even though it may cost less, that's not

the kind of advice that is in and of itself a good idea. "

Wolfe's nonprofit advocacy group often petitions the FDA to withdraw drugs

it believes are unsafe, and highlights those products, now numbering 181, on

its Web site, www.worstpills.org. That service, which costs $15 per year,

lists alternatives to those drugs and sends out alerts when new safety

information becomes available.

Consumers Union's Web-based reports will be updated when new effectiveness,

safety, or cost data appear, Shearer said. Some of those updates will come

from the Drug Effectiveness Review Project, but Consumers Union will also

closely monitor safety and price changes, she said.•

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