Guest guest Posted December 20, 2005 Report Share Posted December 20, 2005 CytoGenix and Aldevron Announce Positive Results of synDNA Hepatitis Vaccine Study 12/19/05 -- CytoGenix, Inc. (OTCBB:CYGX) and Aldevron, LLC announced positive results of a pilot study using CytoGenix synDNA as the active ingredient in a Hepatitis B vaccine, demonstrating that it is highly effective in generating an immune response. DNA vaccines are comprised of genes that confer immunologic protection by producing antigens without the need to expose the body to pathogenic organisms. For this study, CytoGenix scientists prepared a synthetic DNA vaccine derived from a plasmid provided by Aldevron that produces a Hepatitis B viral surface antigen. Aldevron's scientists tested CytoGenix synDNA vaccine's activity in a rabbit model using Aldevron's proprietary Genetic Immunization and Antibody (GIA) technology. Aldevron scientists compared levels of gene-specific serum immunoglobulin produced by the synDNA vaccine to its traditional plasmid DNA vaccine. The synDNA vaccine generated immunoglobulin levels in the test animals up to five times greater than a comparable plasmid DNA vaccine produced by bacterial fermentation. Vazquez, CytoGenix, Inc.'s Executive Vice President and COO, commented, " These results are very important because they confirm the effectiveness of synDNA that we have seen in other animal studies of DNA vaccines. It is clear that our synDNA process produces bio-active DNA. This latest result is a major step forward in our efforts to accelerate CytoGenix' Rapid Response Vaccine Development Program against H5N1 avian flu, smallpox and other infectious disease targets. " Chambers, Aldevron President and CEO, stated, " Aldevron has supported the DNA vaccine field for the past seven years by providing quality DNA, antibody and protein products as well as by sponsoring scientific forums and maintaining the DNAvaccine.com web site. The synDNA process is potentially a big step forward in the DNA vaccine and gene medicine fields. We look forward to expanding Aldevron-CytoGenix scientific and business collaboration. " About CytoGenix: CytoGenix, Inc. is a Houston-based biopharmaceutical company that develops and markets innovative products and services based on its proprietary ssDNA expression technology. The company has developed a breakthrough synthetic process for large-scale production of high purity DNA at a fraction of the cost of traditional fermentation methods. CytoGenix currently has one issued US patent and 41 international or US pending patent applications claiming methods and materials in connection with this platform technology. About Aldevron: With facilities in the United States and Europe, Aldevron offers products and services to DNA vaccine and gene therapy scientists. These include contract bio-manufacturing, genetic immunization and antibody production, and a complete line of gene therapy plasmids. More information can be found at http://www.aldevron.com. SAFE HARBOR: Except for statements of historical fact, the statements in this press release are forward-looking. Such statements are subject to a number of risks and uncertainties that could cause actual results to differ materially from the statements made. These factors include, but are not limited to, general economic conditions, risks associated with the acceptance of new products, competition, and other factors more fully detailed in the company's filings with the Securities and Exchange Commission. Additional information about CytoGenix and its technology can be found on the website at www.cytogenix.com. Source: CytoGenix, Inc. http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=15600029 _________________________________________________________________ Express yourself instantly with MSN Messenger! Download today - it's FREE! http://messenger.msn.click-url.com/go/onm00200471ave/direct/01/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2005 Report Share Posted December 20, 2005 CytoGenix and Aldevron Announce Positive Results of synDNA Hepatitis Vaccine Study 12/19/05 -- CytoGenix, Inc. (OTCBB:CYGX) and Aldevron, LLC announced positive results of a pilot study using CytoGenix synDNA as the active ingredient in a Hepatitis B vaccine, demonstrating that it is highly effective in generating an immune response. DNA vaccines are comprised of genes that confer immunologic protection by producing antigens without the need to expose the body to pathogenic organisms. For this study, CytoGenix scientists prepared a synthetic DNA vaccine derived from a plasmid provided by Aldevron that produces a Hepatitis B viral surface antigen. Aldevron's scientists tested CytoGenix synDNA vaccine's activity in a rabbit model using Aldevron's proprietary Genetic Immunization and Antibody (GIA) technology. Aldevron scientists compared levels of gene-specific serum immunoglobulin produced by the synDNA vaccine to its traditional plasmid DNA vaccine. The synDNA vaccine generated immunoglobulin levels in the test animals up to five times greater than a comparable plasmid DNA vaccine produced by bacterial fermentation. Vazquez, CytoGenix, Inc.'s Executive Vice President and COO, commented, " These results are very important because they confirm the effectiveness of synDNA that we have seen in other animal studies of DNA vaccines. It is clear that our synDNA process produces bio-active DNA. This latest result is a major step forward in our efforts to accelerate CytoGenix' Rapid Response Vaccine Development Program against H5N1 avian flu, smallpox and other infectious disease targets. " Chambers, Aldevron President and CEO, stated, " Aldevron has supported the DNA vaccine field for the past seven years by providing quality DNA, antibody and protein products as well as by sponsoring scientific forums and maintaining the DNAvaccine.com web site. The synDNA process is potentially a big step forward in the DNA vaccine and gene medicine fields. We look forward to expanding Aldevron-CytoGenix scientific and business collaboration. " About CytoGenix: CytoGenix, Inc. is a Houston-based biopharmaceutical company that develops and markets innovative products and services based on its proprietary ssDNA expression technology. The company has developed a breakthrough synthetic process for large-scale production of high purity DNA at a fraction of the cost of traditional fermentation methods. CytoGenix currently has one issued US patent and 41 international or US pending patent applications claiming methods and materials in connection with this platform technology. About Aldevron: With facilities in the United States and Europe, Aldevron offers products and services to DNA vaccine and gene therapy scientists. These include contract bio-manufacturing, genetic immunization and antibody production, and a complete line of gene therapy plasmids. More information can be found at http://www.aldevron.com. SAFE HARBOR: Except for statements of historical fact, the statements in this press release are forward-looking. Such statements are subject to a number of risks and uncertainties that could cause actual results to differ materially from the statements made. These factors include, but are not limited to, general economic conditions, risks associated with the acceptance of new products, competition, and other factors more fully detailed in the company's filings with the Securities and Exchange Commission. Additional information about CytoGenix and its technology can be found on the website at www.cytogenix.com. Source: CytoGenix, Inc. http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=15600029 _________________________________________________________________ Express yourself instantly with MSN Messenger! Download today - it's FREE! http://messenger.msn.click-url.com/go/onm00200471ave/direct/01/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2005 Report Share Posted December 20, 2005 CytoGenix and Aldevron Announce Positive Results of synDNA Hepatitis Vaccine Study 12/19/05 -- CytoGenix, Inc. (OTCBB:CYGX) and Aldevron, LLC announced positive results of a pilot study using CytoGenix synDNA as the active ingredient in a Hepatitis B vaccine, demonstrating that it is highly effective in generating an immune response. DNA vaccines are comprised of genes that confer immunologic protection by producing antigens without the need to expose the body to pathogenic organisms. For this study, CytoGenix scientists prepared a synthetic DNA vaccine derived from a plasmid provided by Aldevron that produces a Hepatitis B viral surface antigen. Aldevron's scientists tested CytoGenix synDNA vaccine's activity in a rabbit model using Aldevron's proprietary Genetic Immunization and Antibody (GIA) technology. Aldevron scientists compared levels of gene-specific serum immunoglobulin produced by the synDNA vaccine to its traditional plasmid DNA vaccine. The synDNA vaccine generated immunoglobulin levels in the test animals up to five times greater than a comparable plasmid DNA vaccine produced by bacterial fermentation. Vazquez, CytoGenix, Inc.'s Executive Vice President and COO, commented, " These results are very important because they confirm the effectiveness of synDNA that we have seen in other animal studies of DNA vaccines. It is clear that our synDNA process produces bio-active DNA. This latest result is a major step forward in our efforts to accelerate CytoGenix' Rapid Response Vaccine Development Program against H5N1 avian flu, smallpox and other infectious disease targets. " Chambers, Aldevron President and CEO, stated, " Aldevron has supported the DNA vaccine field for the past seven years by providing quality DNA, antibody and protein products as well as by sponsoring scientific forums and maintaining the DNAvaccine.com web site. The synDNA process is potentially a big step forward in the DNA vaccine and gene medicine fields. We look forward to expanding Aldevron-CytoGenix scientific and business collaboration. " About CytoGenix: CytoGenix, Inc. is a Houston-based biopharmaceutical company that develops and markets innovative products and services based on its proprietary ssDNA expression technology. The company has developed a breakthrough synthetic process for large-scale production of high purity DNA at a fraction of the cost of traditional fermentation methods. CytoGenix currently has one issued US patent and 41 international or US pending patent applications claiming methods and materials in connection with this platform technology. About Aldevron: With facilities in the United States and Europe, Aldevron offers products and services to DNA vaccine and gene therapy scientists. These include contract bio-manufacturing, genetic immunization and antibody production, and a complete line of gene therapy plasmids. More information can be found at http://www.aldevron.com. SAFE HARBOR: Except for statements of historical fact, the statements in this press release are forward-looking. Such statements are subject to a number of risks and uncertainties that could cause actual results to differ materially from the statements made. These factors include, but are not limited to, general economic conditions, risks associated with the acceptance of new products, competition, and other factors more fully detailed in the company's filings with the Securities and Exchange Commission. Additional information about CytoGenix and its technology can be found on the website at www.cytogenix.com. Source: CytoGenix, Inc. http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=15600029 _________________________________________________________________ Express yourself instantly with MSN Messenger! Download today - it's FREE! http://messenger.msn.click-url.com/go/onm00200471ave/direct/01/ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 20, 2005 Report Share Posted December 20, 2005 CytoGenix and Aldevron Announce Positive Results of synDNA Hepatitis Vaccine Study 12/19/05 -- CytoGenix, Inc. (OTCBB:CYGX) and Aldevron, LLC announced positive results of a pilot study using CytoGenix synDNA as the active ingredient in a Hepatitis B vaccine, demonstrating that it is highly effective in generating an immune response. DNA vaccines are comprised of genes that confer immunologic protection by producing antigens without the need to expose the body to pathogenic organisms. For this study, CytoGenix scientists prepared a synthetic DNA vaccine derived from a plasmid provided by Aldevron that produces a Hepatitis B viral surface antigen. Aldevron's scientists tested CytoGenix synDNA vaccine's activity in a rabbit model using Aldevron's proprietary Genetic Immunization and Antibody (GIA) technology. Aldevron scientists compared levels of gene-specific serum immunoglobulin produced by the synDNA vaccine to its traditional plasmid DNA vaccine. The synDNA vaccine generated immunoglobulin levels in the test animals up to five times greater than a comparable plasmid DNA vaccine produced by bacterial fermentation. Vazquez, CytoGenix, Inc.'s Executive Vice President and COO, commented, " These results are very important because they confirm the effectiveness of synDNA that we have seen in other animal studies of DNA vaccines. It is clear that our synDNA process produces bio-active DNA. This latest result is a major step forward in our efforts to accelerate CytoGenix' Rapid Response Vaccine Development Program against H5N1 avian flu, smallpox and other infectious disease targets. " Chambers, Aldevron President and CEO, stated, " Aldevron has supported the DNA vaccine field for the past seven years by providing quality DNA, antibody and protein products as well as by sponsoring scientific forums and maintaining the DNAvaccine.com web site. The synDNA process is potentially a big step forward in the DNA vaccine and gene medicine fields. We look forward to expanding Aldevron-CytoGenix scientific and business collaboration. " About CytoGenix: CytoGenix, Inc. is a Houston-based biopharmaceutical company that develops and markets innovative products and services based on its proprietary ssDNA expression technology. The company has developed a breakthrough synthetic process for large-scale production of high purity DNA at a fraction of the cost of traditional fermentation methods. CytoGenix currently has one issued US patent and 41 international or US pending patent applications claiming methods and materials in connection with this platform technology. About Aldevron: With facilities in the United States and Europe, Aldevron offers products and services to DNA vaccine and gene therapy scientists. These include contract bio-manufacturing, genetic immunization and antibody production, and a complete line of gene therapy plasmids. More information can be found at http://www.aldevron.com. SAFE HARBOR: Except for statements of historical fact, the statements in this press release are forward-looking. Such statements are subject to a number of risks and uncertainties that could cause actual results to differ materially from the statements made. These factors include, but are not limited to, general economic conditions, risks associated with the acceptance of new products, competition, and other factors more fully detailed in the company's filings with the Securities and Exchange Commission. Additional information about CytoGenix and its technology can be found on the website at www.cytogenix.com. Source: CytoGenix, Inc. http://www.bio.com/industryanalysis/industryanalysis_news.jhtml?cid=15600029 _________________________________________________________________ Express yourself instantly with MSN Messenger! Download today - it's FREE! http://messenger.msn.click-url.com/go/onm00200471ave/direct/01/ Quote Link to comment Share on other sites More sharing options...
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