Blaming more brain chemicals...

[Guest guest]

....rather than acknowledging that some folks have bad luck, crappy

environments, poverty, poor general health, feelings that are unpleasant as

a direct result of bad things happening to them. Couldn't possibly do that,

because then you'd have to fess up to the horrible inequities and problems

in our culture and economy. Better to find more fancy brain chemicals to

blame.)

Health - HealthDay

New Clue to Depression

Thu Jul 8,11:47 PM ET

Add Health - HealthDay to My

THURSDAY, July 8 (HealthDayNews) -- Low brain levels of the inhibitory

transmitter GABA and high levels of the excitatory neurotransmitter

glutamate seem to be strongly associated with melancholic depression, says a

Yale University study in the current issue of the Archives of General

Psychiatry.

Melancholic depression is a common form of depression. Its symptoms include

insomnia, loss of appetite and loss of pleasure.

" Depressed subjects with melancholic features appear to have the largest and

most consistent GABA reductions, " research leader Gerard Sanacora, director

of the Yale Depression Research Program, said in a prepared statement.

" This also appears to be especially clear in the subset of melancholic

subjects who also have psychotic features. In contrast, normal or near

normal GABA concentrations were found in the majority of atypically

depressed subjects, " Sanacora said.

He and his colleagues used proton magnetic resonance spectrometry to record

the levels of GABA and glutamate in 33 people with major depression and 38

healthy people.

The findings could help doctors more accurately diagnosis depression and

provide more effective treatment.

" At the moment, we have limited ability to predict how a patient will

respond to one treatment for depression compared to another, " Sanacora said.

" We are very interested in exploring the usefulness of these and other

biological markers in identifying various subtypes of depression and

predicting specific treatment responses, " he said.

[Guest guest]

I agree. It's crazy not to acknowledge childhood trauma and other

bad experiences at the root of depression. Afterall, early childhood

trauma causes 'neural dysregulation' which leads to low production of

brain serotonin amongst other things. There are environmental

causes, one of which is abuse/trauma.

> ...rather than acknowledging that some folks have bad luck, crappy

> environments, poverty, poor general health, feelings that are

unpleasant as

> a direct result of bad things happening to them. Couldn't possibly

do that,

> because then you'd have to fess up to the horrible inequities and

problems

> in our culture and economy. Better to find more fancy brain

chemicals to

> blame.)

>

> Health - HealthDay

> New Clue to Depression

>

> Thu Jul 8,11:47 PM ET

>

> Add Health - HealthDay to My

>

> THURSDAY, July 8 (HealthDayNews) -- Low brain levels of the

inhibitory

> transmitter GABA and high levels of the excitatory neurotransmitter

> glutamate seem to be strongly associated with melancholic

depression, says a

> Yale University study in the current issue of the Archives of

General

> Psychiatry.

>

> Melancholic depression is a common form of depression. Its symptoms

include

> insomnia, loss of appetite and loss of pleasure.

>

> " Depressed subjects with melancholic features appear to have the

largest and

> most consistent GABA reductions, " research leader Gerard Sanacora,

director

> of the Yale Depression Research Program, said in a prepared

statement.

>

> " This also appears to be especially clear in the subset of

melancholic

> subjects who also have psychotic features. In contrast, normal or

near

> normal GABA concentrations were found in the majority of atypically

> depressed subjects, " Sanacora said.

>

> He and his colleagues used proton magnetic resonance spectrometry

to record

> the levels of GABA and glutamate in 33 people with major depression

and 38

> healthy people.

>

> The findings could help doctors more accurately diagnosis

depression and

> provide more effective treatment.

>

> " At the moment, we have limited ability to predict how a patient

will

> respond to one treatment for depression compared to another, "

Sanacora said.

>

> " We are very interested in exploring the usefulness of these and

other

> biological markers in identifying various subtypes of depression

and

> predicting specific treatment responses, " he said.

[Guest guest]

I agree. It's crazy not to acknowledge childhood trauma and other

bad experiences at the root of depression. Afterall, early childhood

trauma causes 'neural dysregulation' which leads to low production of

brain serotonin amongst other things. There are environmental

causes, one of which is abuse/trauma.

> ...rather than acknowledging that some folks have bad luck, crappy

> environments, poverty, poor general health, feelings that are

unpleasant as

> a direct result of bad things happening to them. Couldn't possibly

do that,

> because then you'd have to fess up to the horrible inequities and

problems

> in our culture and economy. Better to find more fancy brain

chemicals to

> blame.)

>

> Health - HealthDay

> New Clue to Depression

>

> Thu Jul 8,11:47 PM ET

>

> Add Health - HealthDay to My

>

> THURSDAY, July 8 (HealthDayNews) -- Low brain levels of the

inhibitory

> transmitter GABA and high levels of the excitatory neurotransmitter

> glutamate seem to be strongly associated with melancholic

depression, says a

> Yale University study in the current issue of the Archives of

General

> Psychiatry.

>

> Melancholic depression is a common form of depression. Its symptoms

include

> insomnia, loss of appetite and loss of pleasure.

>

> " Depressed subjects with melancholic features appear to have the

largest and

> most consistent GABA reductions, " research leader Gerard Sanacora,

director

> of the Yale Depression Research Program, said in a prepared

statement.

>

> " This also appears to be especially clear in the subset of

melancholic

> subjects who also have psychotic features. In contrast, normal or

near

> normal GABA concentrations were found in the majority of atypically

> depressed subjects, " Sanacora said.

>

> He and his colleagues used proton magnetic resonance spectrometry

to record

> the levels of GABA and glutamate in 33 people with major depression

and 38

> healthy people.

>

> The findings could help doctors more accurately diagnosis

depression and

> provide more effective treatment.

>

> " At the moment, we have limited ability to predict how a patient

will

> respond to one treatment for depression compared to another, "

Sanacora said.

>

> " We are very interested in exploring the usefulness of these and

other

> biological markers in identifying various subtypes of depression

and

> predicting specific treatment responses, " he said.

[Guest guest]

>

>

> I agree. It's crazy not to acknowledge childhood trauma and

other

> bad experiences at the root of depression. Afterall, early

childhood

> trauma causes 'neural dysregulation' which leads to low

production of

> brain serotonin amongst other things. There are

environmental

> causes, one of which is abuse/trauma.

Blake Graham's site,

http://www.nutritional-healing.com.au

can show many ways to heal the brain without drugs.

[Guest guest]

>

>

> I agree. It's crazy not to acknowledge childhood trauma and

other

> bad experiences at the root of depression. Afterall, early

childhood

> trauma causes 'neural dysregulation' which leads to low

production of

> brain serotonin amongst other things. There are

environmental

> causes, one of which is abuse/trauma.

Blake Graham's site,

http://www.nutritional-healing.com.au

can show many ways to heal the brain without drugs.