Re: Divided doses vs single dose

February 20, 2004

The conventional wisdom was that the advantage of Tapazole over PTU (the

other anti-thyroid drug) was that it could be taken only once a day rather

than 3 times a day. However, a new study (sorry I don't have a url for you

but a google search should find it) recently showed that Tapazole, too, is

more effective in 3 divided doses, especially at the beginning of treatment

when you need to both lower blood levels of thyroid hormone and deplete

hormone stored in the thyroid.

Therefore, I would take it in 3, 10mg doses at least to start.

Good luck! Nissa

Divided doses vs single dose

>I am newly diagnosed with Grave's disease, and my endocrinologist

>prescribed 30 mg of Tapazole daily, in 10 mg tablets. He stated, " you

>can take all three tablets at once each day. "

>

>Are there any studies that show whether divided doses or a single

>daily dose result in better outcomes?

>

>I have not yet started the medication, but would like to begin

>tomorrow am. Thanks, in advance, for your response.

>

February 24, 2004

If anyone has the reference for this study, will you please post it?

Thanks so much!

-- In hyperthyroidism , " Nissa Kagle " <nissa@v...> wrote:

> a new study (sorry I don't have a url for you

> but a google search should find it) recently showed that Tapazole,

too, is

> more effective in 3 divided doses, especially at the beginning of

treatment

> when you need to both lower blood levels of thyroid hormone and deplete

> hormone stored in the thyroid.

February 25, 2004

Perhaps the package insert would suffice.

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