Armour thyroid

June 18, 2008

--- In thyroid treatment , " jenny stenning "

<jennystenning@...> thanks for that i thought she may have been

able to buy over the counter like in Spain and Portugal you can

purchase most drugs that way dont know about thyroid meds though and

Spain is cheaper than here. In Portugal drugs are expensive .

>I thought she might of been able to get 3 grains over there.Guess

ill have to order 1 grain as i am on 3 1/2 now its so unfair how much

more expensive it will be but it is worth it to feel this well thanks

once again Marie

>

> -----

> Subject: armour thyroid

> but could she

> purchase some Armour without prescription over there and bring it

back

> for me in higher grains hopefully. Marie

>

> ------------------------------------

>

> Messages are not a substitute for professional medical advice.

Always

> consult with a suitably qualified practitioner before changing

> medication.

June 19, 2008

Hi Marie

My order from inhouse turned up yesterday took nearly 3 weeks but then

customs got thier hands on it. So if you order now you should get it in

time.

Ali

x

>

> Hi all have just upped my armour to 3 1/2 grains and no side effects

> but my concern is the shortage of armour i have enough for 4 weeks

then

> i am up the creek like every one else. (I have a niece who is a

> genetic engineer in Baltimore due to come back and take up a job in

> Aberdeen working with whales )nothing to do with this but could she

> purchase some Armour without prescription over there and bring it

back

> for me in higher grains hopefully. Marie

>

June 19, 2008

Hi Marie,

Have you thought of trying the Nature-Throid IPS also stock -it's

much cheaper. I used it for a while a few years ago and didn't notice any

difference from Armour, though it does have different fillers if that is a

concern for you.

Subject: Re: armour thyroid

Guess

ill have to order 1 grain as i am on 3 1/2 now its so unfair how much

more expensive it will be but it is worth it to feel this well thanks

once again Marie

>

> -----

------------------------------------

Messages are not a substitute for professional medical advice. Always

consult with a suitably qualified practitioner before changing

medication.

June 24, 2008

I have noticed some changes in how I feel lately too. I have had to change

my dosages - went from 240 mgs to 2 - 120 mgs (felt fine) to now 4 - 60 mgs

because of the recall. It is when I got to the 60 mgs that I started to

feel really tired all the time. I don't know if it is the armour but I have

heard that the reason why the higher dosages are not out yet is that they

are waiting on FDA approval post mfgr changes. I don't know if they changed

the formulation for the lower pills. I was stable on 4 grs. UGH!

Armour Thyroid

>I have been using Armour Thyroid for several years. Just with this

> last bottle, I have begun having migraines which I have correlated

> with ingesting 1/2 of the 60mg pill. I believe it is either rancid or

> that they have changed the formula. I would like to know if others

> have had any adverse reactions to this product. Puts me between a rock

> and a hard place as I need it for treatment of Hashimoto's

> Thyroiditis. But can't imagine taking something which is making me ill.

> Savvy

>

> ------------------------------------

>

June 24, 2008

Here is the phone number for Forest Labs : 1-800-947-5227. If you

call, ask for Pam. Hoping to learn how this formula might have

changed over time. Or could it be rancid? Does have polyethelene

glycol in it, it seems. Plus Titanium Dioxide. Plus the various

other excipients they use. I think it is contaminated, but can't be

sure. Just know I get migraines from this pill!

Savvy

>

> I have noticed some changes in how I feel lately too. I have had

to change

> my dosages - went from 240 mgs to 2 - 120 mgs (felt fine) to now

4 - 60 mgs

> because of the recall. It is when I got to the 60 mgs that I

started to

> feel really tired all the time. I don't know if it is the armour

but I have

> heard that the reason why the higher dosages are not out yet is

that they

> are waiting on FDA approval post mfgr changes. I don't know if

they changed

> the formulation for the lower pills. I was stable on 4 grs. UGH!

>

> Armour Thyroid

>

> >I have been using Armour Thyroid for several years. Just with

this

> > last bottle, I have begun having migraines which I have

correlated

> > with ingesting 1/2 of the 60mg pill. I believe it is either

rancid or

> > that they have changed the formula. I would like to know if

others

> > have had any adverse reactions to this product. Puts me between

a rock

> > and a hard place as I need it for treatment of Hashimoto's

> > Thyroiditis. But can't imagine taking something which is making

me ill.

> > Savvy

> >

> > ------------------------------------

> >

June 24, 2008

I have talked to Pam. I actually started the whole potency mess with the 4

grains back in October. I was the first to report an issue with tanking

thyroid levels. When I told them I was a thyca patient they freaked and had

me talk to the FDA adverse reaction reports dept. I know Pam very well. I

am not reporting another thing. I will see Dr. Brownstein on 7/2 and get my

labs then. If they are dropping I will find out then and then deal with it

if necessary. There are just too many variables in my life now to

definitively tie it to Armour - like I could last time.

Armour Thyroid

>>

>> >I have been using Armour Thyroid for several years. Just with

> this

>> > last bottle, I have begun having migraines which I have

> correlated

>> > with ingesting 1/2 of the 60mg pill. I believe it is either

> rancid or

>> > that they have changed the formula. I would like to know if

> others

>> > have had any adverse reactions to this product. Puts me between

> a rock

>> > and a hard place as I need it for treatment of Hashimoto's

>> > Thyroiditis. But can't imagine taking something which is making

> me ill.

>> > Savvy

>> >

>> > ------------------------------------

>> >

June 24, 2008

This is interesting, I had not heard of a recall of armour. I had asked

my doc to change me to Armour about 2 months ago, had been taking 12.5

mcg of cytomel for years. He prescribed 1 grain (60 mg?) of Armour,

and I felt worse so I just went back to the cytomel. Is it only the 60

mg pill that may be contaminated? That's what I was using.

I can't tell if it was just the Armour or something else, since my

neighbor sprayed an herbicide and I've also been reacting to that.

JIll

June 24, 2008

My kids take 60 mgs plus a 30 mg tablet. There was a recall on all 3,4 and

5 grain tablets last November ('07).

Steph

Re: Re: Armour Thyroid

> This is interesting, I had not heard of a recall of armour. I had asked

> my doc to change me to Armour about 2 months ago, had been taking 12.5

> mcg of cytomel for years. He prescribed 1 grain (60 mg?) of Armour,

> and I felt worse so I just went back to the cytomel. Is it only the 60

> mg pill that may be contaminated? That's what I was using.

>

> I can't tell if it was just the Armour or something else, since my

> neighbor sprayed an herbicide and I've also been reacting to that.

> JIll

>

> ------------------------------------

>

June 24, 2008

Thanks for the information, Steph.

Jill

ladybugsandbees wrote:

>

> My kids take 60 mgs plus a 30 mg tablet. There was a recall on all 3,4

> and

> 5 grain tablets last November ('07).

>

> Steph

>

> Re: Re: Armour Thyroid

>

> > This is interesting, I had not heard of a recall of armour. I had asked

> > my doc to change me to Armour about 2 months ago, had been taking 12.5

> > mcg of cytomel for years. He prescribed 1 grain (60 mg?) of Armour,

> > and I felt worse so I just went back to the cytomel. Is it only the 60

> > mg pill that may be contaminated? That's what I was using.

> >

> > I can't tell if it was just the Armour or something else, since my

> > neighbor sprayed an herbicide and I've also been reacting to that.

> > JIll

> >

> > ------------------------------------

> >

June 24, 2008

Savvy, You could be alergic to the Armour. Which you can get cleared with an NAET practioner in your area to clear it if that is the problem.

Are you also taking Iodine in some form, Celtic sea salt loading, vit C, selenuim ??

Armour Thyroid

I have been using Armour Thyroid for several years. Just with this last bottle, I have begun having migraines which I have correlated with ingesting 1/2 of the 60mg pill. I believe it is either rancid or that they have changed the formula. I would like to know if others have had any adverse reactions to this product. Puts me between a rock and a hard place as I need it for treatment of Hashimoto's Thyroiditis. But can't imagine taking something which is making me ill.Savvy

June 24, 2008

DR Brownstein has me on Nature-throid and said it is the same as

Armour. Wouldn't it be easier to be on that, rather than, always

having this mess with Armour? Just wondering.

Janie

> >>

> >> I have noticed some changes in how I feel lately too. I have had

> > to change

> >> my dosages - went from 240 mgs to 2 - 120 mgs (felt fine) to now

> > 4 - 60 mgs

> >> because of the recall. It is when I got to the 60 mgs that I

> > started to

> >> feel really tired all the time. I don't know if it is the armour

> > but I have

> >> heard that the reason why the higher dosages are not out yet is

> > that they

> >> are waiting on FDA approval post mfgr changes. I don't know if

> > they changed

> >> the formulation for the lower pills. I was stable on 4 grs.

UGH!

> >>

> >> Armour Thyroid

> >>

> >> >I have been using Armour Thyroid for several years. Just with

> > this

> >> > last bottle, I have begun having migraines which I have

> > correlated

> >> > with ingesting 1/2 of the 60mg pill. I believe it is either

> > rancid or

> >> > that they have changed the formula. I would like to know if

> > others

> >> > have had any adverse reactions to this product. Puts me between

> > a rock

> >> > and a hard place as I need it for treatment of Hashimoto's

> >> > Thyroiditis. But can't imagine taking something which is making

> > me ill.

> >> > Savvy

> >> >

> >> > ------------------------------------

> >> >

June 24, 2008

They are not interchangeable. I tried it and tanked in 8 days. My daughter

tried it and tanked in 4.

Steph

Armour Thyroid

>> >>

>> >> >I have been using Armour Thyroid for several years. Just with

>> > this

>> >> > last bottle, I have begun having migraines which I have

>> > correlated

>> >> > with ingesting 1/2 of the 60mg pill. I believe it is either

>> > rancid or

>> >> > that they have changed the formula. I would like to know if

>> > others

>> >> > have had any adverse reactions to this product. Puts me between

>> > a rock

>> >> > and a hard place as I need it for treatment of Hashimoto's

>> >> > Thyroiditis. But can't imagine taking something which is making

>> > me ill.

>> >> > Savvy

>> >> >

>> >> > ------------------------------------

>> >> >

June 24, 2008

So they are not the same? Could that be why I felt more energy at

first but now am soooo tired all the time? Still trying to figure out

this tired thing. I am tired of being tired.

Janie

> >> >>

> >> >> I have noticed some changes in how I feel lately too. I have

had

> >> > to change

> >> >> my dosages - went from 240 mgs to 2 - 120 mgs (felt fine) to

now

> >> > 4 - 60 mgs

> >> >> because of the recall. It is when I got to the 60 mgs that I

> >> > started to

> >> >> feel really tired all the time. I don't know if it is the

armour

> >> > but I have

> >> >> heard that the reason why the higher dosages are not out yet

is

> >> > that they

> >> >> are waiting on FDA approval post mfgr changes. I don't know

if

> >> > they changed

> >> >> the formulation for the lower pills. I was stable on 4 grs.

> > UGH!

> >> >>

> >> >> Armour Thyroid

> >> >>

> >> >> >I have been using Armour Thyroid for several years. Just

with

> >> > this

> >> >> > last bottle, I have begun having migraines which I have

> >> > correlated

> >> >> > with ingesting 1/2 of the 60mg pill. I believe it is either

> >> > rancid or

> >> >> > that they have changed the formula. I would like to know if

> >> > others

> >> >> > have had any adverse reactions to this product. Puts me

between

> >> > a rock

> >> >> > and a hard place as I need it for treatment of Hashimoto's

> >> >> > Thyroiditis. But can't imagine taking something which is

making

> >> > me ill.

> >> >> > Savvy

> >> >> >

> >> >> > ------------------------------------

> >> >> >

June 24, 2008

No it happens when you switch from Armour to Naturethyroid. I never had

energy doing that just slowly got more tired. I won't take long because T4

has a half life of 6 days so you will feel it soon. I'll bet yours is

something else.

Armour Thyroid

>> >> >>

>> >> >> >I have been using Armour Thyroid for several years. Just

> with

>> >> > this

>> >> >> > last bottle, I have begun having migraines which I have

>> >> > correlated

>> >> >> > with ingesting 1/2 of the 60mg pill. I believe it is either

>> >> > rancid or

>> >> >> > that they have changed the formula. I would like to know if

>> >> > others

>> >> >> > have had any adverse reactions to this product. Puts me

> between

>> >> > a rock

>> >> >> > and a hard place as I need it for treatment of Hashimoto's

>> >> >> > Thyroiditis. But can't imagine taking something which is

> making

>> >> > me ill.

>> >> >> > Savvy

>> >> >> >

>> >> >> > ------------------------------------

>> >> >> >

February 13, 2009

Afshin from International Pharmacy has now contacted me to give me the

latest up-to-date information about Armour thyroid and International

Pharmacy.

Luv - Sheila

_______________________________

I am now certain that armour 2 grain will be available the week of

February 20th. I have added it to the site now. I have also lowered

the price of lower strengths of armour a little. Demand has gone down

and I no longer have to buy from New Jersey at additional cost and

shipping fee to supplement my local supply.

I have plenty of supply of the higher strengths of armour on hand.

RLC Lab still has no release date for the 2 and 3 grain Nature-Throid

or Westhroid.

Regards,

afshin

February 13, 2009

Thats great news as I was waiting for the 2 grains to come in so will order some soon. Thanks sheila

Afshin from International Pharmacy has now contacted me to give me thelatest up-to-date information about Armour thyroid and InternationalPharmacy.Regards,afshin

April 7, 2009

It's definitely available in Belgium at the pharmacies listed on this site:

http://www.geocities.com/thyroide/pharm-Belgique.html

April 7, 2009

I have never really done any real research into this, but what I

do know is that Armour is available within the UK with a prescription as

mentioned in the letter from the MHRA for those people who don't do well on

levothyroxine only. Armour is also available in Belgium at the pharmacies

listed in the link you sent enkai. I do know that many

people in Paris pop over to Belgium to get their Armour thyroid without a

problem. Thyroid extract is also is also available in Canada called

“Thyroid USP” and is produced by Erfa Pharmaceutical, and in

Australia natural thyroid extract is also available. I heard that Stenlake

Pharmacy in Australia get their thyroid powder from America where all thyroid

powder comes from because it is absolutely consistent. Ar you out there P at

the moment, and able to help us on this one?

Many doctors realise it is the best treatment, but because it is

a natural product, it is not patentable - so no money can be made and those 'responsible'

for teaching about hypothyroid therapy do encourage students to stay away from

natural thyroid extract insisting that it is 'dangerous " despite it having

been used safely and effectively for over 100 years. The NHS need to make money

- though it would be nice to have the knowledge that they need to make patients

well as number one priority.

I understand that in the

Netherlands, they have at least one pharmacy importing Armour Thyroid via the

Broda organisation.Broda hold the marketing rights for Armour

Thyroid, USP. The Dutch I understand can go over the border and buy Armour

Thyroid (with prescription) in a pharmacy in Antwerp in Belgium. They can buy

it cheaper in Belgium than the Netherlands. All the desiccated thyroid powder

used in the Netherlands used to come from Kastrup in Denmark, but they now get

it from America, where everybody gets their thyroid powder. A prescription to purchase

thyroid extract in the Netherland is required.

Can anybody else throw any

light on the natural thyroid extract situation in other countries please, but

especially about Armour Thyroid, Nature Throid and West throid.

luv - Sheila

It's definitely available in Belgium at the

pharmacies listed on this site:

http://www.geocities.com/thyroide/pharm-Belgique.html

April 8, 2009

These

guys ought to get their facts. Why would the FDA approve a medication in which

there were " potency issues in different batches " ? Why would the MHRA

tell UK medical practitioners they can prescribe Armour Thyroid within the NHS

for those patients who do not do well on levothyroxine, if there were

" potency issues in different batches " . This is the ugly rumour the

BTA (along with drug reps from the makers of levothyroxine) are trying to

spread around to stop people getting Armour Thyroid. The T4 and T3 in every

tablet of Armour is standardised to the United States Specifications (USP)

required by the FDA. If the T4 and T3 were NOT standardised, Armour thyroid

would indeed, be a very dangerous drug, and neither the FDA or the MHRA would

have approved its use. How crazy are these people. Perhaps you need to pass

this on to him enkai.

Luv

- Sheila

STEVEN

L. RICHHEIMER AND CHARLOTTE B. JENSEN

Received

February 14, 1985, from the Quality Control Laboratory, Pharmaceutical Basics,

Inc., Denver, CO 80223.

Accepted

for publication November 14, 1985.

Abstract

Liothyronine

and levothyroxine were quantitatively determined in samples of commercial

thyroid tablets and bulk powders. Samples were first hydrolyzed using a

bacterial protease and then analyzed by high-performance liquid chromatography.

Various hydrolysis conditions were investigated. The liothyronine and

levothyroxine contents of commercial tablets and bulk powders were found to be

8-11 mcg and 25-43 mcg, respectively, per 65 mg of thyroid. The stability of

the iodothyronines in thyroid tablets was also investigated.

The

U.S.P. method[1] for the high-performance liquid chromatographic (HPLC)

determination of liothyronine (T3) and levothyroxine (T4) obtained from

enzymatic digestion of desiccated thyroid and thyroid tablets is based on that

of Rees- and Larsen.[2] These authors reported that 65 mg (1 grain) of

thyroid tablets contained —12 mcg of liothyronine (T3) and 64 mcg of

levothyroxine (T4), determining the iodothyronine contents by radioimmunoassay

(RIA) instead of HPLC. Other investigators have reported considerably lower

recoveries of liothyronine (T3) and levothyroxine (T4) following enzymatic

digestion of desiccated thyroid and thyroid tablets[3-8] Initial attempts to

reproduce the results of Rees- and Larsen[2] using the proposed HPLC method

of analysis on a variety of thyroid tablets and bulk material gave liothyronine

(T3) and levothyroxine (T4) recoveries of only -50-60 of those reported.

Chromatographic difficulties were encountered using the cyano column specified,

and the small incubation volume (0.55 mL) made it impossible to |obtain

adequate hydrolysis on most tablets in which the proportion of excipients to

desiccated thyroid was large. Hence, studies were undertaken to determine the

optimum conditions for the hydrolysis and chromatography of liothyronine (T3)

and levothyroxine (T4) present in commercially available thyroid tablets. As a

result of the studies which are 'reported here and studies performed

collaboratively at other laboratories (Armour Pharmaceutical Co., Eli Lilly

Pharmaceutical Co., and the National Center for Drug Analysis, Food and Drug

Administration), the Pharmacopeial Convention made revisions in USP XXI via the

Second Interim Revision Announcement.9 Limits of 8.1—9..9mg of

liothyronine (T3) and 32.3-43.7 mg levothyroxine (T4) per 65 mg (1I grain) were

adopted.

Experimental

Section

Reagents

and Materials—U.S.P. reference standards of levothyroxine and

liothyronine were used undried. Moisture content was determined by the Karl

Fischer titration method, and a correction was made. L-3,3',5'-triiodothyronine

(T3, reverseT3, or iso-T3, Calbiochem-Behring Corp., San Diego, CA) was used as

received. Bacterial protease derived from Streptomyces griseus was obtained

from two sources (Pronase, catalog #53702, Calbiochem-Behring ;Corp.; Bacterial

Protease, catalog #P5147, Sigma Chemical Co., St. ;Louis, MO). Reagents used

were analytical reagent grade, and acetonitrile was HPLC grade. Iodine assays

were done by potentiometric titration using silver nitrate and an iodide-sensing

electrode.[10] Thyroid tablets were obtained from several manufacturers

(Pharmaceutical Basics, Inc., Denver, CO; Armour Pharmaceutical Co., Scotsdale,

AZ; Eli Lilly Co., Indianapolis, IN), and bulk thyroid was either full strength

(-0.8 iodine, American Laboratories, Inc., Omaha, NE) or cut with lactose to

0.2 iodine content (Pharmaceutical Basics, Inc., Denver, CO).

Apparatus—The

high-performance liquid chromatograph (HPLC) (model 5500, Varian Instruments,

Palo Alto, CA) was equipped with a variable-wavelength detector (Varian model

UV-200), column heater, auto sampler (Varian model 8000), and auto injector

(model 7126, Rheodyne Corp., Cotati, CA) with a 200-L loop. Data was handled by

a chromatographic data system equipped with a 144K memory, disk storage, and a

printer plotter (Varian, Vista 402). A commercially available 4 mm ID x 30 cm

octadecylsilane column (A-Bondapak-Cia, Waters Associates, Milford, MA) was

used.

Chromatographic

Conditions—The mobile phase was a mixture of 28 acetonitrile and 72 of a

1:200 mixture of phosphoric acid in water. The percentage of acetonitrile was

increased to about 35 when a spherical 5-/nm Cig column packing was used. The

flow rate was either 1.5 or 2.0 mL per minute, the column temperature was 34°C,

and the detector was set at 225 nm.

Proteolytic

Enzyme Solution—A pH 8.4 reducing buffer solution was prepared containing

0.11 M NaCI, 0.04 M Tris buffer, and 0.05 M methimazole. The pH was adjusted to

8.4 ± 0.05 with 6 M HC1. On the day of use the proteolytic enzyme was dissolved

in the reducing buffer to prepare a solution containing —150 protease

units per milliliter (1 unit liberates a digestion product equivalent to 25 µg

of tyrosine per minute).

Stock

Standard Solutions—Levothyroxine (95 mg) was dissolved in 100 mL of a

500:500:1 mixture of water:acetonitrile:ammonia hydroxide. Similarly,

liothyronine (22.5 mg) was dissolved in 25.0 mL of the same mixture. A working

combination stock solution was then prepared by combining 4.0 mL of the

levothyroxine stock and 1.0 mL of the liothyronine stock and diluting to 10.0

mL with a 1:1 mixture of acetonitrile and water. This combination stock was

stable for -2 months when stored at 4°C in the dark.

Working

Standard—On the day of use, the combination stock was diluted 1:50 with

the reducing buffer solution. Then, 2.0 mL of enzyme deactivating solution

(1:100 phosphoric acid:acetonitrile) was added to 5.0 mL of the diluted

standard. The final concentrations of liothyronine (T3) and levothyroxine (T4)

were -1.3 mcg/mL and 5.4 mcg/mL, respectively.

Recovery

Standard—The combination stock standard was diluted 1:50 with proteolytic

enzyme solution instead of reducing buffer and treated in the same manner as

the samples. Sample Preparation—An accurately weighed portion of powder

equivalent to 65 mg (1 grain) of thyroid (proportionately less was used if the

iodine content was greater than 0.2) was transferred to a screw-capped culture

tube, 5.0 mL of proteolytic enzyme solution was added, and the contents were

mixed well. The tubes were placed in an incubator maintained at 37 ± 1°C, and

the contents were agitated after 4-8 h and again after 20-24 h. At the end of

the incubation period (28 h); 2.0 mL of enzyme deactivating solution was added,

and the tubes were mixed well, and centrifuged at about 2000 rpm for 5-10 min.

Some samples required filtration through a 0.45-/xm membrane filter in order to

clarify the sample.

Results

and Discussion

Chromatography—Table

1 shows a typical chromatogram obtained for a 65-mg thyroid tablet. The small

peak at 14 min had the same retention time as L-,3',5'-triiodothyronine CIV,

1). The approximate amount of 1 was found to be about 1.0-1.6 /zg/65 mg of

thyroid. The presence of 1 in thyroid has also been reported by other

investigators,4-7 and its presence in samples precluded the use of 1 as a

convenient internal standard.

0022-3549/86/0200-0215$01.00/0

©

1986, American Pharmaceutical Association

Journal

of Pharmaceutical Sciences/215

Vol.

75, No. 2, February 1986

OPEN

FORUM

Liothyronine

and Levothyroxine in Armour Thyroid

The

current United States Pharmacopeia (U.S. Pharmacopeia) method[1] for the

analysis of liothyronine (T3) and levothyroxine (T4) in desiccated thyroid

requires a proteolytic enzymatic digestion followed by a high-performance

liquid chromatographic assay. These procedures were validated through a

collaborative study at four laboratories[2] in which one-grain thyroid tablets

from three manufacturers were assayed in triplicate on five consecutive days.

The final results of this study were submitted to the U.S. Pharmacopeia to

assist them in establishing both the analytical procedures and the

specifications for thyroid tablets, U.S.P.

In

the February, 1986 issue of the Journal of Pharmaceutical Sciences, Richheimer

and Jensen of Pharmaceutical Basics[3] published further data developed on

thyroid products manufactured by Armour, Lilly, and Pharmaceutical Basics. The

Pharmaceutical Basics data suggest that the Armour product failed to meet the

current U.S. Pharmacopeia specifications for T3 (i.e., 8.1-9.9 µg/grain). Not

included in the publication were the original data that were obtained from all

the participating laboratories, including Pharmaceutical Basics, Inc. (PBI),

and submitted to the U.S. Pharmacopeia. These results formed the basis for the

current U.S. Pharmacopeia specifications for T3 and T4 in natural thyroid. The

original results obtained for the Armour product (Lot 1516), as well as PBI

published data, are shown in Table I.

It

can be clearly seen that with the exception of the second set of results

provided by Pharmaceutical Basics, the Armour 1-grain (65 mg) thyroid product

contains levels of liothyronine and levothyroxine that are well within the

limits specified by the U.S. Pharmacopeia. It is interesting to note that the

overall composite values for liothyronine and levothyroxine are quite similar

to the mean values of the two sets of results from Pharmaceutical Basics.

Additionally, the precision of the assay as demonstrated by Armour, Eli Lilly,

and the FDA was significantly better than that obtained by Pharmaceutical

Basics for their first analysis and for levothyroxine in the second set of

data.

The above results should serve to

correct any misrepresentations (implied or otherwise) reported previously (see

below) regarding the liothyronine and levothyroxine content in Armour thyroid

medications and the nature of the collaborative study for the U.S.

Pharmacopeia. As determined by Armour Pharmaceutical Company and other participating

laboratories, the liothyronine and levothyroxine content in Armour thyroid is

well within the specifications set by the U.S. Pharmacopeia. The precision of

the assay procedure as determined by Armour, Eli Lilly, and the FDA is

considerably better than that reported by Pharmaceutical Basics.

Table

1 — Liothyronine (T3) and Levothyroxine (T4) Content in Thyroid tablets

Laboratory Analysis Liothyronine (T3) Levothyroxine

(T4)

Mean Range RSD Mean Range RSD

Table

1 — Liothyronine (T3) and Levothyroxine (T4) Content in

Thyroid tablets

Laboratory

Analysis

Liothyronine (T3)

Levothyroxine (T4)

Mean

Range

RSD

Mean

Range

RSD

Armour0

Eli Lilly

FDA

PBI (1)

PBI (III)

Composite

PBI—Mean

14

15

13

8.88

8.58

8.60

9.51

7.96

8.71

8.74

8.58 - 9.04

8.33 - 8.76

7.73 - 9.65

8.57 - 11.21

7.27 - 8.56

1.81

2.99

6.43

7.9

5.3

37.68

37.30

39.47

40.90

36.66

38.30

38.78

36.62 - 38.32

35.6 - 38.2

38.19 - 40.50

34.16 - 45.48

33.53 - 44.27

1.39

3.26

3.30

9.9

8.1

1. US

Pharmacopeia, 21st rev.; U.S. Pharmacopeial Convention: Rockville, MD, 1985; pp

1893-1895

2. Armour

Pharmaceutical Company, Eli Lilly Pharmaceutical Company, The National Center

for Drug Analysis (FDA), and Pharmaceutical Basics, Inc.

3. Richheimer,

S. L.; Jensen, C. B. J. Pharm. Sci. 1986, 75, 215-217.

KARL

R. BLUMBERG

WILLIAM

J. MAYER

DILIP

K. PARIKH

LORNE

A. SCHNELL

Armour

Pharmaceutical Company

P.O.

Box 511

Kankakee,

IL 60901

Received

October 22, 1986.

Accepted

for publication February 3, 1987.

ALL

OF THE FOREGOING EXTRACTS WERE TAKEN FROM THE MONOGRAPH ON ARMOUR THYROID USP

AND WERE UNDERTAKEN AS A RESPONSE TO

THE

FOLLOWING REPORT

Response

to " Liothyronine and Levothyroxine in Armour Thyroid "

We

originally conducted the collaborative study to determine the levothyroxine

(T4) and liothyronine (T3) content of thyroid tablets from three different

manufacturers in late September 1984. Because of a deadline we had to send

these results to R. Gamick at Armour Pharmaceutical Co. even though we were not

happy with the results; that is, the T4 and T3 levels we found were 10-15%

higher than we had gotten before and others had reported. As a result of this,

we initiated a study to determine the cause of this anomaly and found that our

standard stock solution had undergone extensive degradation (probably from

being inappropriately stored at room temperature for several days). We then

repeated the study using fresh standards and reported these new results

directly to the U.S. Pharmacopeia on October 19, 1984, with instructions to

disregard the previous data we had obtained. This second set of data is what is

reported in our paper in the February 1986 issue of the Journal of

Pharmaceutical Sciences. To the best of our knowledge this set of data was in

the hands of the U.S. Pharmacopeia Committee on Revision when they decided upon

the final specifications for thyroid tablets.

STEVEN

L RICHHEIMER

CHARLOTTE

D. JENSEN

Quality

Control Laboratory

Pharmaceutical

Basics, Inc.

Denver,

CO 80223

a.

USP XXl specification: 8.1 to 9.9 mcg/65mg (1 grain) b. USP specification: 32.3

to 43.7mcg/65mg (1 grain) c.Lot 1516; 1-grain, tablets. d. pharmaceutical

basics, Inc e. reference 3

From: thyroid treatment

[mailto:thyroid treatment ] On Behalf Of enkai111

Sent: 08 April 2009 00:50

thyroid treatment

Subject: Re: Armour Thyroid

found

this person from Sweden commenting about Armour in Sweden.....

Mikael Jansson said...

You guys in the US are lucky. In Sweden, you have to beg to even get T3

(synthetic form, of course), and the main treatment is levothyroxine.

To get Armour Thyroid, you have to apply for a *license* with the Swedish

equivalent to the FDA, and even then, you have to have been on medication for a

year w/ stable values, but residual symptoms for a sub-functioning thyroid.

The common argument against is that the T4-to-T3 ratio is too high (which is

why you take one in the morning, and one in the afternoon, duh...), as well as

non-standardised doses. The latter claim was recently changed to " potency

issues in different batches " . Well, it is my understanding that levothyroxin

also suffers from this, at laest judging from the past problems with Synthroid

in the US.

But perhaps the main problem is that Nycomed, the company producing the most

common medication (Levaxin), seem to be unhealthily tight with the

endocrinologists. Plus, of course, hypothyroidism being listed in the MDs

guidebooks as being something easy to treat with synthetic T4 replacement...

http://heartscanblog.blogspot.com/2009/01/bargains-for-armour-thyroid.html

No virus found in this

incoming message.

Checked by AVG - www.avg.com

Version: 8.0.238 / Virus Database: 270.11.44/2044 - Release Date: 04/07/09

17:53:00

April 8, 2009

Hi Sheila,

In addition, the bioavailability was in doubt for Levothyroxine.

They have subsequently been asked to tighten up the bioavailability for Levothyroxine to plus/minus 5% of the stated dose.

The manufacturers of Levothryoxine are obviously behind this latest push to get Armour off the market since it's bioavailability isn't in doubt, but they maintain (spuriously) that it is. Whilst we're on the subject of false beliefs and false statements:-

Why would a 'rogue' protein like calcitonin be such an obscure and trivial protein if it didn't do anything and then, of course, there's the salmon calcitonin (patent covered?) that doesn't treat anything in particular?

The let's pretend we don't know anything about calcitonin, whilst damning the use of Armour (for containing any in the first place).

Sometimes, profound ignorance is covered up by conspiratorial silence (else that's for other motives ~ not just 'commercial confidentiality').

The paradox, that they would want to maintain the 'fibs' that drug reps put about, is also significant ~ in a criminal sense.

Gouging the NHS, and by inference gouging the patients, who have to put up with the inconvenient side-effects (denied by refusal to submit yellow form ADRs ... reps maintain they're not ADRs).

It's not as though we aren't aware of what's going on......the magnitude of a criminal conspiracy is just that, unbelievable until you dig deeper.....then you discover that the entire system is being systematically corrupted to the knowledge of the major Journal Editors ~ belatedly shamed into doing something about it, through the very brazenness with which it has been perpetrated.

The latest withdrawals of papers (21) by Reuben et al to name but some.

best wishesBob

>> These guys ought to get their facts. Why would the FDA approve a medication in which there were "potency issues in different batches"? Why would the MHRA tell UK medical practitioners they can prescribe Armour Thyroid within the NHS for those patients who do not do well on levothyroxine, if there were "potency issues in different batches". This is the ugly rumour the BTA (along with drug reps from the makers of levothyroxine) are trying to spread around to stop people getting Armour Thyroid.

April 8, 2009

Does anybody know how we can find out how many woman are taking Armour

in the UK alone?

Luv - Sheila

I am fascinated with what you find out Bob.

Hi Sheila,

In addition, the bioavailability

was in doubt for Levothyroxine.

They have subsequently been asked to tighten up the bioavailability for Levothyroxine to

plus/minus 5% of the stated dose.

The manufacturers of Levothryoxine are obviously behind this latest push to

get Armour off the market since it's bioavailability isn't in doubt, but they

maintain (spuriously) that it is.

Whilst we're on the subject of false beliefs and false statements:-

Why would a 'rogue' protein like calcitonin be such an obscure and trivial

protein if it didn't do anything and then, of course, there's the salmon

calcitonin (patent covered?) that doesn't treat anything in particular?

The let's pretend we don't know anything about calcitonin, whilst damning

the use of Armour (for containing any in the first place).

Sometimes, profound ignorance is covered up by conspiratorial silence (else

that's for other motives ~ not just 'commercial confidentiality').

The paradox, that they would want to maintain the 'fibs' that drug reps put

about, is also significant ~ in a criminal sense.

Gouging the NHS, and by inference gouging the patients, who have to put up

with the inconvenient side-effects (denied by refusal to submit yellow form

ADRs ... reps maintain they're not ADRs).

It's not as though we aren't aware of what's going on......the magnitude of

a criminal conspiracy is just that, unbelievable until you dig deeper.....then

you discover that the entire system is being systematically corrupted to the

knowledge of the major Journal Editors ~ belatedly shamed into doing something

about it, through the very brazenness with which it has been perpetrated.

The latest withdrawals of papers (21) by Reuben et al to name but some.

best wishes

Bob

>

> These guys ought to get their facts. Why would the FDA approve a

medication in which there were " potency issues in different batches " ?

Why would the MHRA tell UK medical practitioners they can prescribe Armour

Thyroid within the NHS for those patients who do not do well on levothyroxine,

if there were " potency issues in different batches " . This is the ugly

rumour the BTA (along with drug reps from the makers of levothyroxine) are

trying to spread around to stop people getting Armour Thyroid.

No virus

found in this incoming message.

Checked by AVG - www.avg.com

Version: 8.0.238 / Virus Database: 270.11.46/2046 - Release Date: 04/07/09

17:53:00

April 8, 2009

>

> Can somebody let me know just which countries Armour is available in beside

> the USA please. You might need to do a little searching.

>

> Luv - Sheila

>

A little while ago I did a search for dessicated thyroid in Argentina, as my son

is out there at present. On an ex-pat site it said that there had been some

available but that now it has totally disappeared leaving only thyroxine.

Ex-pat sites are good for info like this.

April 8, 2009

Thank you Janet - I think they are trying to get it banned

world-wide.

luv - Sheila

>

> Can somebody let me know just which countries Armour is available in

beside

> the USA please. You might need to do a little searching.

>

> Luv - Sheila

>

A little while ago I did a search for dessicated thyroid in Argentina, as my

son is out there at present. On an ex-pat site it said that there had been some

available but that now it has totally disappeared leaving only thyroxine.

Ex-pat sites are good for info like this.

No virus

found in this incoming message.

Checked by AVG - www.avg.com

Version: 8.0.238 / Virus Database: 270.11.46/2046 - Release Date: 04/07/09

17:53:00

April 8, 2009

''Thank you Janet - I think they are trying to get it banned world-wide''.

Yes Shiela, and doing a darned good job of it too. They cannot have assertive

ex-sick people can they? They might realise they have lost most of their life to

inferior medication.

lotsa luv

Dawnx

April 8, 2009

What I cant get my head around is that Forrest just dont do anything about the

attempts to bury their product....they just ignore it all.

jennyfreeman

> Thank you Janet - I think they are trying to get it banned world-wide.

>

> luv - Sheila

>

> >

> > Can somebody let me know just which countries Armour is available in

> beside

> > the USA please. You might need to do a little searching.

> >

> > Luv - Sheila

> >

> A little while ago I did a search for dessicated thyroid in Argentina, as my

> son is out there at present. On an ex-pat site it said that there had been

> some available but that now it has totally disappeared leaving only

> thyroxine. Ex-pat sites are good for info like this.

>

> No virus found in this incoming message.

> Checked by AVG - www.avg.com

> Version: 8.0.238 / Virus Database: 270.11.46/2046 - Release Date: 04/07/09

> 17:53:00

>

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