Tyrosine

[Guest guest]

Insulin-Like Growth Factor-I (IGF-I)

IGF-I (originally called somatomedin C) is a growth factor

structurally related to insulin. IGF-I is the primary protein involved

in responses of cells to growth hormone (GH): that is, IGF-I is

produced in response to GH and then induces subsequent cellular

activities, particularly on bone growth. It is the activity of IGF-I

in response to GH that gave rise to the term somatomedin. Subsequent

studies have demonstrated, however, that IGF-I has autocrine and

paracrine activities in addition to the initially observed endocrine

activities on bone. The IGF-I receptor, like the insulin receptor, has

intrinsic tyrosine kinase activity. Owing to their structural

similarities IGF-I can bind to the insulin receptor but does so at a

much lower affinity than does insulin itself.

http://web.indstate.edu/thcme/mwking/growth-factors.html#intro

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> > > > Can you explain the mechanism how No-Fenol allows more tyrosine?

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[Guest guest]

Dev Med Child Neurol. 2001 Sep;43(9):614-6. Related Articles, Links

Low levels of insulin-like growth factor-I in cerebrospinal fluid

in children with autism.

Vanhala R, Turpeinen U, Riikonen R.

Unit of Child Neurology, Hospital for Children and Adolescents,

Helsinki, Finland. raija.vanhala@...

Autism is a behaviourally defined syndrome characterized by

disturbances of social interaction and communication and restrictions

of behaviour patterns and imagination. The pathogenesis of autism is

unknown but it is suspected that a number of genetic factors may be

involved. Neurotrophic factors such as insulin-like growth factor-I

(IGF-I) play a role in early brain development. The aim of this study

was to determine whether IGF-I levels might be associated with the

development of autism. IGF-I levels were measured in the CSF of 11

children with autism (4 females, 7 males; mean age 3.8 years, SD 1.1)

using a sensitive radioimmunoassay method and compared with levels in

11 control participants (6 females, 5 males; mean age 3.8 years).

Levels of IGF-I in the CSF were statistically significantly lower in

the children with autism than in the control children (p=0.03). IGF-I

may play a role in pathogenetic mechanisms of autism and the role of

neurotrophic factors in autism and other neurodevelopmental diseases

should be studied further.

Publication Types:

* Clinical Trial

* Controlled Clinical Trial

PMID: 11570630 [PubMed - indexed for MEDLINE]

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[Guest guest]

It is also the main reason for athletes taking growth hormone, as this

results in higher levels of IGF-1. An anabolic state is the main

desire of most bodybuilders and this is the domain of IGF-1. Increased

cell division and increased protein synthesis, stimulation of wound

healing, production of immune cells, reduction of insulin demand and

increased burning of fat, these are the functions of this hormone.

Also anti-catabolic (check out the cortisol article), as demonstrated

in several pathological states, IGF-1 is the most anabolic of all the

growth factors present in whey.

http://maxmag.maxsportsinternational.com/science/issue38/38sci1.htm

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> > > > > > Can you explain the mechanism how No-Fenol allows more

> tyrosine?

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[Guest guest]

interesting about whey being anabolic(which i had to look up,

anabolic: promoting synthesis, opposite of catabolic) not quite sure

scd is right in trying to eliminate wheys cause of the

lactose............

how does cortisol fit into this?

body building must be a perseveration.

> It is also the main reason for athletes taking growth hormone, as

this

> results in higher levels of IGF-1. An anabolic state is the main

> desire of most bodybuilders and this is the domain of IGF-1.

Increased

> cell division and increased protein synthesis, stimulation of wound

> healing, production of immune cells, reduction of insulin demand and

> increased burning of fat, these are the functions of this hormone.

> Also anti-catabolic (check out the cortisol article), as

demonstrated

> in several pathological states, IGF-1 is the most anabolic of all

the

> growth factors present in whey.

>

> http://maxmag.maxsportsinternational.com/science/issue38/38sci1.htm

>

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[Guest guest]

Dear all,

I read that Tyrosine can support both Adrenal and Thyroid. But I

heard that it would cause anxiety. I am very anxious. Can I take it?

Anything can substitue it?

Thanks,

Chan.

[Guest guest]

"She basically said that some people, especially native americans, are very efficient users of things like tyrosine. I happen to be 1/8 Cherokee." -- Cara

Cara, tyrosine seems to be very closely connected with iodine. In addition to being the base for the thyroid hormones, T3 and T4, iodine and tyrosine seem to have other relationships. You might find the following research studies of interest; both of them are talking about the relationship between iodine and tyrosine (and histidine).

A newly discovered oxidant defence system and its involvement in the development of Aurelia aurita (Scyphozoa, Cnidaria): [reactive oxygen species and elemental iodine control medusa formation.] Berking S, Czech N, Gerharz M, Herrmann K, Hoffmann U, Raifer H, Sekul G, Siefker B, Sommerei A, Vedder F, 2005. "In Aurelia aurita, applied iodine induces medusa formation (strobilation). This process also occurs when the temperature is lowered. This was found to increase oxidative stress resulting in an increased production of iodine from iodide....We argue that an oxidant defence system may exist which makes use of iodide and tyrosine....Both substances together, iodide and tyrosine, form an efficient oxidant defence system which shields the tissue against damage by reactive oxygen species. In the course of evolution (from a species at the basis of the animal kingdom like Aurelia to a highly evolved species like man) the waste product thyroxin (indicating a high metabolic rate) has developed into a hormone which controls the metabolic rate." Abstract (+ free article if you'll click to recommend that your library purchases the journal)

How iodine kills viruses -- Derry Email 1105. "Dilute iodine solutions kill all single celled organisms such as bacteria, viruses, fungi, and protozoa. Not only are Lugol's solutions bactericidal at high dilutions, like 1/170,000, for standard pathogens such as Staphylococcus, but also iodine has the broadest range of action, fewest side effects, and no development of bacterial resistance....Single celled organisms blissfully reproduced themselves with structural membrane proteins having the amino acid tyrosine or histidine exposed to the surrounding medium or extra-cellular fluids. Iodine kills single celled organisms by combining with these same two amino acids. All single celled organisms showing tyrosine (tyrosyl) linkages exposed in the membrane proteins are killed by this simple chemical reaction that denatures proteins and kills the cells."

I don't know where this iodine - tyrosine connection is going to lead us, but somehow it seems very significant.

Zoe

[Guest guest]

Chuck,

 

I was asking for inexpensive supplemental sources of tyrosine.  BTW, I do not

have hives.

> I would like input too. My doc recommended nature-throid, tyrosine and

> iodine also. Anybody have a cheap source of tyrosine?

Cheese, nuts, soy, exactly the foods to avoid if you have hives, which

tyrosine aggravates.

[Guest guest]

one of the best things for hashimoto is low dose naltrexone.some people report

improvement.

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> do you feel it is useful to take tyrosine as a help for hashimoto's?? why or

why not?? thanks

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Zahavi,

What is naltrexone?

one of the best things for hashimoto is low dose naltrexone.some people report improvement.>> > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks>

[Guest guest]

here you can read about low dose naltrexone

http://www.low dose naltrexone.org/

for all auto-immune diseases, copd,parkinson cancer autism and every one that

was long time under stress it is the most amazing treatment.

there is also a very good group for help

low dose naltrexone/

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> > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why

or why not?? thanks

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thank you...i joined the site too....sounds very promising!

From: zahavi <zahavi100@...>Subject: Re: tyrosineiodine Date: Friday, August 14, 2009, 6:03 AM

here you can read about low dose naltrexonehttp://www.lowdosen altrexone. org/for all auto-immune diseases, copd,parkinson cancer autism and every one that was long time under stress it is the most amazing treatment.there is also a very good group for help http://health. groups.. com/group/ lowdosenaltrexon e/> >> > > > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks> >>

[Guest guest]

i wish you success.i have seen amazing results with ldn.copd,AS,crohn,hepatetis.

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> > > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why

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these are the results for my 11 year old..i already have 2 kids with hashi's...she is on about 6.5 mg of iodine...selenium 100 mcg, magnesium, iron 85 mg at night...methlated b complex...vitamin d3she has had past anxiety and mild adhd...her tsh was 2.9 (.360-5.8)FT3 4.3 (2.6-5.7)FT4 1.02 (0.79-1.49)ferritin 31 (10-291)i am wondering if her tsh is a bit elevated due to iodine intake...her ft3 seems to be in upper range ft4 is right in middle...what do you think...i am soooo tired of my kids needing all these tests...so far this child has not had antibody testing..i am trying to raise her ferritin and give iodine time to work on her...she has only been on it for about 3 months....any advice??

From: meredithsenter <meredithsenter>Subject: Re: Re: tyrosineiodinegroups (DOT) comDate: Thursday, August 13, 2009, 4:21 PM

How so? What were the benefits to gluten free and ldn. Has anyone benefitted from tyrosineSent from my Verizon Wireless BlackBerry Re: Re: tyrosineYes, I could not agree more!! For me, the only thing that was morehelpfull than LDN is when I begin a gluten/grain free diet!2009/8/13 zahavi <zahavi100gmail (DOT) com>>>>> one of the best things for hashimoto is low dose naltrexone.some people report improvement.>> > >> >> > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks> >>------------ --------- --------- ------

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Here Free T4 looks like my children when they began taking Armour. IMHO it's too low. 4.6 is the beginning of the upper 1/3 of the range and she isn't there. Most feel best in the upper 1/3 of the range. Mid range isn't going to cut it. Ferritin is too low. Should be 50-60. Her TSH is too high. The only way to know if it is iodine related is to take a thyroglobulin level. It is elevated when attempting to bind to iodine. I would like to see antibodies here too. Is she gluten free? That may help ADHD issues along with removing dairy. I know she's 11 and that is hard. Sounds like she has some adrenal issues. Is her face clear or does she have acne? How are her cycles? Does she have mood swings with her cycles? You have part of the puzzle and my guess is she is hypo and could use a boost. Puberty makes you need more thyroid hormone.

Steph

Re: Re: tyrosineYes, I could not agree more!! For me, the only thing that was morehelpfull than LDN is when I begin a gluten/grain free diet!2009/8/13 zahavi <zahavi100gmail (DOT) com>>>>> one of the best things for hashimoto is low dose naltrexone.some people report improvement.>> > >> >> > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks> >>------------ --------- --------- ------

[Guest guest]

My children take it M/W/F My son is almost 10.

Steph

Re: Re: tyrosineYes, I could not agree more!! For me, the only thing that was morehelpfull than LDN is when I begin a gluten/grain free diet!2009/8/13 zahavi <zahavi100gmail (DOT) com>>>>> one of the best things for hashimoto is low dose naltrexone.some people report improvement.>> > >> >> > do you feel it is useful to take tyrosine as a help for hashimoto's? ? why or why not?? thanks> >>------------ --------- --------- ------

[Guest guest]

I tried tyrosine last year after reading a book by Dr Cousens

where he spoke at length about balancing amino acids. It gave me a

seriously upset stomach if taken without food, and even with food, it

didn't sit well.

Jana

dawn volz wrote:

>do you feel it is useful to take tyrosine as a help for hashimoto's?? why or

why not?? thanks

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Could it have been the particular brand you used? It's really hard to find pure products as almost "everyone" puts magnesium stearate and/or stearic acid in their supplements... All I know is that whenever possible I'm ordering powdered supplements to encapsulate myself.Raquel> > >do you feel it is useful to take tyrosine as a help for hashimoto's?? why or why not?? thanks > >> > > >>