Re: Is your high-salt program slowly killing you?

[Guest guest]

Dear Duncan

Are you a naturopath? Do you have a practice somewhere? If so, can you tell us

where?

Helen

Duncan Crow <duncancrow@...> wrote:

High-salt diet linked to kidney, brain damage and oxidative stress.

In both human and experimental salt-sensitive hypertension,

superoxide production and renal damage are increased, antioxidant

capacity is decreased, and antioxidant therapy can be helpful, note

the researchers.

FULLTEXT:

http://members.shaw.ca/duncancrow/salt_hypertension_superoxide_renal.p

df (PDF)

-unbreakable URL:

http://tinyurl.com/yxqrzx

The study, " Oxidative Stress: The Curse That Underlies Cerebral

Vascular Dysfunction " , highlights the brain damage: " Oxidative stress

in the vasculature appears to be a common feature in diverse models

of cerebral vascular disease and injury. ...Many of these same risk

factors have also been linked with vascular cognitive impairment and

Alzheimer disease. ...Nitric oxide (NO), a potent vasodilator, is a

major mediator of endothelium-dependent relaxation and thus regulator

of tone in large arteries and microvessels of the brain. NO reacts

extremely efficiently with superoxide, resulting in loss of NO

bioavailability. "

FULLTEXT: http://members.shaw.ca/duncancrow/Oxidative-Stress-and-

Cerebral-Vascular-Dysfunction.pdf (PDF)

(Advances in Stroke 2004, M. Faraci, PhD)

-unbreakable URL:

http://tinyurl.com/ycv5nx

In " Role of superoxide and angiotensin II suppression in salt-induced

changes in endothelial Ca2+ signaling and NO production in rat

aorta " , the researchers observed increased superoxide in the high-

salt group.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

db=pubmed & cmd=Retrieve & dopt=AbstractPlus & list_uids=16603691 & query_hl=1

& itool=pubmed_docsum

-unbreakable URL:

http://tinyurl.com/ylnkkj

The increased oxidation is independent of a hypertension reaction.

The study, " Effect of high-salt diet on NO release and superoxide

production in rat aorta " , notes, " ...the present study demonstrates

that impaired endothelium-dependent relaxation, reduced NO release,

and increased superoxide production also may occur during elevated

salt intake in normotensive animals. "

FULLTEXT:

http://members.shaw.ca/duncancrow/salt_superoxide_low_nitric_oxide.pdf

-unbreakable URL:

http://tinyurl.com/ufglm

In fact, superoxide helps to cause salt-sensitive hypertension; the

study " Superoxide contributes to development of salt sensitivity and

hypertension induced by nitric oxide deficiency " points out that " The

development of any imbalance between oxidative and antioxidative

processes in living tissues would lead to derangements in organ

function including the kidney. The results of the present study,

which demonstrate a close relation between enhancement of superoxide

and the development of salt sensitivity during NOS inhibition,

provide an important clue in our quest in understanding the

pathophysiology of salt-sensitive hypertension. "

FULLTEXT:

http://members.shaw.ca/duncancrow/salt_hypertension_superoxide_low_nit

ric_oxide.pdf

-unbreakable tinyurl:

http://tinyurl.com/yjpb97

Here we have validation for dietary prevention of disease using

antioxidants, with this April 2005 study, " Antioxidant treatment

prevents renal damage and dysfunction and reduces arterial pressure

in salt-sensitive hypertension " .

FULLTEXT:

http://members.shaw.ca/duncancrow/salt_antioxidants_prevent_damage_hyp

ertension.pdf

-unbreakable tinyurl:

http://tinyurl.com/ylqzlh

When excess salt results in the depletion of antioxidant and nitric

oxide it can aggravate many inflammatory and/or oxidative disorders.

In lung issues like asthma and COPD for example, antioxidant

glutathione and nitric oxide are known to be depleted; this depletion

leads to increased airway constriction and superoxide, peroxide and

other free radical damage, which is accompanied by more irritation

and mucous production, symptoms that often go away when levels are

replete. This review " Oxidative stress and antioxidant deficiencies

in asthma: potential modification by diet " and several related

articles accessible from on this page make the point.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

db=pubmed & cmd=Retrieve & dopt=AbstractPlus & list_uids=16354413 & query_hl=6

& itool=pubmed_docsum

-unbreakable tinyurl:

http://tinyurl.com/ybj7p9

Excess salt also depletes cellular potassium; potassium supplements

and high-potassium food may be needed to balance a high-salt diet and

avoid the cell death and tissue wasting condition of rhabdomyolysis.

One would avoid and reverse early stages of kidney scarring and

fibrosis, which is the biggest cause of renal failure in the elderly,

with oral fibrinolytic enzymes.

Duncan Crow

http://members.shaw.ca/duncancrow

Send instant messages to your online friends http://au.messenger.

[Guest guest]

Helen, I'm a consultant living in Duncan BC Canada.

Duncan

[Guest guest]

This revisits dangerous advice on that promotes high

salt yet eschews potassium to balance it.

[From: " ransley " <ransley@...>]

Duncan is absolutely right and I have firsthand experience with this.

Potassium Orotate worked best for me. Daddybob

[in response to:]

I would like to caution people on the salt-C protocol to avoid

potassium imbalance -- supplementing potassium will avoid the tissue

wasting of rhabdomyolysis caused by excess salt or potassium

depletion, which is the same wasting disorder as that caused by statin

drugs. The most at-risk tissues are the highest ATP users, the heart

muscle and the brain, then the other muscles. Not good.

Have you heard that most of us are potassium-deficient already?

Duncan

>

> High-salt diet linked to kidney, brain damage and oxidative stress.

>

> In both human and experimental salt-sensitive hypertension,

> superoxide production and renal damage are increased, antioxidant

> capacity is decreased, and antioxidant therapy can be helpful, note

> the researchers.

>

> FULLTEXT:

>

http://members.shaw.ca/duncancrow/salt_hypertension_superoxide_renal.p

> df (PDF)

> -unbreakable URL:

> http://tinyurl.com/yxqrzx

>

> The study, " Oxidative Stress: The Curse That Underlies Cerebral

> Vascular Dysfunction " , highlights the brain damage: " Oxidative

stress

> in the vasculature appears to be a common feature in diverse models

> of cerebral vascular disease and injury. ...Many of these same risk

> factors have also been linked with vascular cognitive impairment

and

> Alzheimer disease. ...Nitric oxide (NO), a potent vasodilator, is a

> major mediator of endothelium-dependent relaxation and thus

regulator

> of tone in large arteries and microvessels of the brain. NO reacts

> extremely efficiently with superoxide, resulting in loss of NO

> bioavailability. "

> FULLTEXT: http://members.shaw.ca/duncancrow/Oxidative-Stress-and-

> Cerebral-Vascular-Dysfunction.pdf (PDF)

> (Advances in Stroke 2004, M. Faraci, PhD)

> -unbreakable URL:

> http://tinyurl.com/ycv5nx

>

> In " Role of superoxide and angiotensin II suppression in salt-

induced

> changes in endothelial Ca2+ signaling and NO production in rat

> aorta " , the researchers observed increased superoxide in the high-

> salt group.

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

>

db=pubmed & cmd=Retrieve & dopt=AbstractPlus & list_uids=16603691 & query_hl=1

> & itool=pubmed_docsum

> -unbreakable URL:

> http://tinyurl.com/ylnkkj

>

> The increased oxidation is independent of a hypertension reaction.

> The study, " Effect of high-salt diet on NO release and superoxide

> production in rat aorta " , notes, " ...the present study demonstrates

> that impaired endothelium-dependent relaxation, reduced NO release,

> and increased superoxide production also may occur during elevated

> salt intake in normotensive animals. "

> FULLTEXT:

>

http://members.shaw.ca/duncancrow/salt_superoxide_low_nitric_oxide.pdf

> -unbreakable URL:

> http://tinyurl.com/ufglm

>

> In fact, superoxide helps to cause salt-sensitive hypertension; the

> study " Superoxide contributes to development of salt sensitivity

and

> hypertension induced by nitric oxide deficiency " points out

that " The

> development of any imbalance between oxidative and antioxidative

> processes in living tissues would lead to derangements in organ

> function including the kidney. The results of the present study,

> which demonstrate a close relation between enhancement of

superoxide

> and the development of salt sensitivity during NOS inhibition,

> provide an important clue in our quest in understanding the

> pathophysiology of salt-sensitive hypertension. "

> FULLTEXT:

>

http://members.shaw.ca/duncancrow/salt_hypertension_superoxide_low_nit

> ric_oxide.pdf

> -unbreakable tinyurl:

> http://tinyurl.com/yjpb97

>

> Here we have validation for dietary prevention of disease using

> antioxidants, with this April 2005 study, " Antioxidant treatment

> prevents renal damage and dysfunction and reduces arterial pressure

> in salt-sensitive hypertension " .

> FULLTEXT:

>

http://members.shaw.ca/duncancrow/salt_antioxidants_prevent_damage_hyp

> ertension.pdf

> -unbreakable tinyurl:

> http://tinyurl.com/ylqzlh

>

> When excess salt results in the depletion of antioxidant and nitric

> oxide it can aggravate many inflammatory and/or oxidative

disorders.

> In lung issues like asthma and COPD for example, antioxidant

> glutathione and nitric oxide are known to be depleted; this

depletion

> leads to increased airway constriction and superoxide, peroxide and

> other free radical damage, which is accompanied by more irritation

> and mucous production, symptoms that often go away when levels are

> replete. This review " Oxidative stress and antioxidant deficiencies

> in asthma: potential modification by diet " and several related

> articles accessible from on this page make the point.

> http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?

>

db=pubmed & cmd=Retrieve & dopt=AbstractPlus & list_uids=16354413 & query_hl=6

> & itool=pubmed_docsum

> -unbreakable tinyurl:

> http://tinyurl.com/ybj7p9

>

> Excess salt also depletes cellular potassium; potassium supplements

> and high-potassium food may be needed to balance a high-salt diet

and

> avoid the cell death and tissue wasting condition of

rhabdomyolysis.

> One would avoid and reverse early stages of kidney scarring and

> fibrosis, which is the biggest cause of renal failure in the

elderly,

> with oral fibrinolytic enzymes.

>

> Duncan Crow

> http://members.shaw.ca/duncancrow

>

[Guest guest]

I have been taking some potassium supplements - how much should I be taking

daily?

Belinda

[Guest guest]

Belinda, again, a sliding scale; people on a high-salt program need

more potassium, and people on low salt and high-vegetables, because

veggies contain poatssium, need less potassium supplement.

That being said, I don't use salt at all personally, relying on

casual exposure through processed meats and whatever salt is in

normal meat etc. I salt my food with " No-Salt " which is a potassium

rather than a sodium salt. What this does is alkalinize the body;

cells contain 50 TIMES the potassium that the blood and lymph do.

OK, so, one to five grams daily might be a useful supplement; I use a

lot of veggies and about 2 grams of No-salt at the most, which

probably gives me about 1/2 gram of elemental potassium.

Duncan

>

> I have been taking some potassium supplements - how much should I

be taking daily?

>

> Belinda

>

>

>

[Guest guest]

duncan,

does a diet high in fats and high is salts cause

further damage to your body?

I wason a program which was highin fats and high in

sea salts and began to feel worse with the addition of

these two.

thanx

sue

________________________________________________________________________________\

____

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[Guest guest]

High salt can be dangerous due to increased hypertension, increased

oxidation (free radical damage) and unbalanced electrolytres (mainly

potassium shortage to balance the sodium). I wouldn't use it myself.

High fat usually is not dangerous, if its saturated fat.

Duncan

>

>

> duncan,

>

> does a diet high in fats and high is salts cause

> further damage to your body?

>

> I wason a program which was highin fats and high in

> sea salts and began to feel worse with the addition of

> these two.

>

> thanx

>

> sue