Guest guest Posted December 3, 2007 Report Share Posted December 3, 2007 yikes I can see the judges face if I used that !!! do you have the study ?? and would someone please contact me off list to give me an update on the lawsuits ?? I need something for hope . Hope begins in the dark, the stubborn hope that if you just show up and try to do the right thing , the dawn will come . You wait and watch and work: You do not give up. ~ Anne LamottCheck out AOL Money Finance's list of the hottest products and top money wasters of 2007. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 3, 2007 Report Share Posted December 3, 2007 Dr. Dan ~ At first I thought you were joking, poking some clever fun at EtG testing. I should have known better. You were serious!!! Forensic Sci Int. 2007 Nov 8 Ethyl glucuronide: Unusual distribution between head hair and pubic hair. Kintz P, Villain M, Vallet E, Etter M, Salquebre G, Cirimele V. Laboratoire ChemTox, 3 rue Grüninger, 67400 Illkirch, France. " Ethyl glucuronide (EtG) is a minor metabolite of ethanol that can be detected in hair. In some specific situations, head hair can be missing, and therefore, alternative anatomical locations of hair are of interest. In this study, paired hair specimens (head hair and pubic hair) from eight social drinkers were analyzed for EtG. Each sample was decontaminated by two dichloromethane bathes (5ml) for 2min. After cutting into small pieces, about 50mg of hair was incubated in 2ml water in the presence of 10ng of EtG-d(5), used as internal standard and submitted to ultra-sonication for 2h. The aqueous phase was extracted by SPE using Oasis MAX columns. The hair extract was separated on an ACQUITY BEH HILIC column using a gradient of acetonitrile and formate buffer. Detection was based on two daughter ions: transitions m/z 221-85 and 75 and m/z 226-75 for EtG and the IS, respectively. This laboratory is using a positive cut-off at 50pg/mg. All eight head hair specimens were negative for EtG at a limit of quantitation fixed at 10pg/mg. Surprisingly, EtG was identified at high concentrations in pubic hair, in the range 12- 1370pg/mg. It appears, therefore, that it is not possible to document the drinking status of a subject by simply switching from head hair to pubic hair. " PMID: 17997064 " The fur is going to fly " ...I love it! Henny > > Helander has published new research showing that pubic hair contains a > much higher concentration of etg than social drinkers head hair. I > would therefore think if you were a hairy person you would be more > likely to have higher concetrations of etg in your marital appendages > even if you shaved. And how do we keep hair out of our specimens? > Without a hair filter from the start all etg specimens are invalid!! > The fur is going to fly!!!DD2 > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2007 Report Share Posted December 4, 2007 thanks dd2 the britanny spears syndrome henny...shave your head so you your drug use history cannot be collected...now more shaving will be required it seems...Henny <hennipen14@...> wrote: Dr. Dan ~ At first I thought you were joking, poking some clever fun at EtG testing. I should have known better. You were serious!!! Forensic Sci Int. 2007 Nov 8 Ethyl glucuronide: Unusual distribution between head hair and pubic hair.Kintz P, Villain M, Vallet E, Etter M, Salquebre G, Cirimele V.Laboratoire ChemTox, 3 rue Grüninger, 67400 Illkirch, France."Ethyl glucuronide (EtG) is a minor metabolite of ethanol that can be detected in hair. In some specific situations, head hair can be missing, and therefore, alternative anatomical locations of hair are of interest. In this study, paired hair specimens (head hair and pubic hair) from eight social drinkers were analyzed for EtG. Each sample was decontaminated by two dichloromethane bathes (5ml) for 2min. After cutting into small pieces, about 50mg of hair was incubated in 2ml water in the presence of 10ng of EtG-d(5), used as internal standard and submitted to ultra-sonication for 2h. The aqueous phase was extracted by SPE using Oasis MAX columns. The hair extract was separated on an ACQUITY BEH HILIC column using a gradient of acetonitrile and formate buffer. Detection was based on two daughter ions: transitions m/z 221-85 and 75 and m/z 226-75 for EtG and the IS, respectively. This laboratory is using a positive cut-off at 50pg/mg. All eight head hair specimens were negative for EtG at a limit of quantitation fixed at 10pg/mg. Surprisingly, EtG was identified at high concentrations in pubic hair, in the range 12-1370pg/mg. It appears, therefore, that it is not possible to document the drinking status of a subject by simply switching from head hair to pubic hair." PMID: 17997064"The fur is going to fly"...I love it!Henny>> Helander has published new research showing that pubic hair contains a > much higher concentration of etg than social drinkers head hair. I > would therefore think if you were a hairy person you would be more > likely to have higher concetrations of etg in your marital appendages > even if you shaved. And how do we keep hair out of our specimens? > Without a hair filter from the start all etg specimens are invalid!! > The fur is going to fly!!!DD2> Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2007 Report Share Posted December 4, 2007 oh.......I thought this was a joke at first too, but then it hit me........I almost forgot that NOTHING surprises me when it comes to EtG testing and the use and ABUSE of this ridiculous test....thanks for sharing the info! You know no one on the " outside " would ever believe this stuff if they came across it nonchalantly in a magazine or newspaper!thanks! joy:) > > > > Helander has published new research showing that pubic hair > contains a > > much higher concentration of etg than social drinkers head hair. I > > would therefore think if you were a hairy person you would be more > > likely to have higher concetrations of etg in your marital > appendages > > even if you shaved. And how do we keep hair out of our specimens? > > Without a hair filter from the start all etg specimens are > invalid!! > > The fur is going to fly!!!DD2 > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2007 Report Share Posted December 4, 2007 No kidding, Joy, about others not getting/believing it re: EtG. And why should they, it's so damn absurd?! It's like we have our own little Secret Society. I never envisioned anything of the likes of this when I started recovery over 5 yrs ago. Thank goodness we have each other !!! Marshajoyous1_1210 <joyous1_1210@...> wrote: oh.......I thought this was a joke at first too, but then it hit me........I almost forgot that NOTHING surprises me when it comes to EtG testing and the use and ABUSE of this ridiculous test....thanks for sharing the info! You know no one on the "outside" would ever believe this stuff if they came across it nonchalantly in a magazine or newspaper!thanks! joy:)> >> > Helander has published new research showing that pubic hair > contains a > > much higher concentration of etg than social drinkers head hair. I > > would therefore think if you were a hairy person you would be more > > likely to have higher concetrations of etg in your marital > appendages > > even if you shaved. And how do we keep hair out of our specimens? > > Without a hair filter from the start all etg specimens are > invalid!! > > The fur is going to fly!!!DD2> >> Be a better pen pal. Text or chat with friends inside . See how. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2007 Report Share Posted December 4, 2007 is anyone actually doing hair analysis for etg in their monitoring program? ---- Henny <hennipen14@...> wrote: > Dr. Dan ~ At first I thought you were joking, poking some clever fun > at EtG testing. I should have known better. You were serious!!! > > Forensic Sci Int. 2007 Nov 8 > Ethyl glucuronide: Unusual distribution between head hair and pubic > hair. > Kintz P, Villain M, Vallet E, Etter M, Salquebre G, Cirimele V. > Laboratoire ChemTox, 3 rue Grüninger, 67400 Illkirch, France. > > " Ethyl glucuronide (EtG) is a minor metabolite of ethanol that can be > detected in hair. In some specific situations, head hair can be > missing, and therefore, alternative anatomical locations of hair are > of interest. In this study, paired hair specimens (head hair and > pubic hair) from eight social drinkers were analyzed for EtG. Each > sample was decontaminated by two dichloromethane bathes (5ml) for > 2min. After cutting into small pieces, about 50mg of hair was > incubated in 2ml water in the presence of 10ng of EtG-d(5), used as > internal standard and submitted to ultra-sonication for 2h. The > aqueous phase was extracted by SPE using Oasis MAX columns. The hair > extract was separated on an ACQUITY BEH HILIC column using a gradient > of acetonitrile and formate buffer. Detection was based on two > daughter ions: transitions m/z 221-85 and 75 and m/z 226-75 for EtG > and the IS, respectively. This laboratory is using a positive cut-off > at 50pg/mg. All eight head hair specimens were negative for EtG at a > limit of quantitation fixed at 10pg/mg. Surprisingly, EtG was > identified at high concentrations in pubic hair, in the range 12- > 1370pg/mg. It appears, therefore, that it is not possible to document > the drinking status of a subject by simply switching from head hair > to pubic hair. " PMID: 17997064 > > " The fur is going to fly " ...I love it! > > Henny > > > > > > > Helander has published new research showing that pubic hair > contains a > > much higher concentration of etg than social drinkers head hair. I > > would therefore think if you were a hairy person you would be more > > likely to have higher concetrations of etg in your marital > appendages > > even if you shaved. And how do we keep hair out of our specimens? > > Without a hair filter from the start all etg specimens are > invalid!! > > The fur is going to fly!!!DD2 > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2007 Report Share Posted December 4, 2007 Never did do hair screening, Henny--- & thanks to my HP I am done with monitoring finally!!! Marsha arein862@... wrote: is anyone actually doing hair analysis for etg in their monitoring program?---- Henny <hennipen14 > wrote: > Dr. Dan ~ At first I thought you were joking, poking some clever fun > at EtG testing. I should have known better. You were serious!!! > > Forensic Sci Int. 2007 Nov 8 > Ethyl glucuronide: Unusual distribution between head hair and pubic > hair.> Kintz P, Villain M, Vallet E, Etter M, Salquebre G, Cirimele V.> Laboratoire ChemTox, 3 rue Grüninger, 67400 Illkirch, France.> > "Ethyl glucuronide (EtG) is a minor metabolite of ethanol that can be > detected in hair. In some specific situations, head hair can be > missing, and therefore, alternative anatomical locations of hair are > of interest. In this study, paired hair specimens (head hair and > pubic hair) from eight social drinkers were analyzed for EtG. Each > sample was decontaminated by two dichloromethane bathes (5ml) for > 2min. After cutting into small pieces, about 50mg of hair was > incubated in 2ml water in the presence of 10ng of EtG-d(5), used as > internal standard and submitted to ultra-sonication for 2h. The > aqueous phase was extracted by SPE using Oasis MAX columns. The hair > extract was separated on an ACQUITY BEH HILIC column using a gradient > of acetonitrile and formate buffer. Detection was based on two > daughter ions: transitions m/z 221-85 and 75 and m/z 226-75 for EtG > and the IS, respectively. This laboratory is using a positive cut-off > at 50pg/mg. All eight head hair specimens were negative for EtG at a > limit of quantitation fixed at 10pg/mg. Surprisingly, EtG was > identified at high concentrations in pubic hair, in the range 12-> 1370pg/mg. It appears, therefore, that it is not possible to document > the drinking status of a subject by simply switching from head hair > to pubic hair." PMID: 17997064> > "The fur is going to fly"...I love it!> > Henny> > > > >> > Helander has published new research showing that pubic hair > contains a > > much higher concentration of etg than social drinkers head hair. I > > would therefore think if you were a hairy person you would be more > > likely to have higher concetrations of etg in your marital > appendages > > even if you shaved. And how do we keep hair out of our specimens? > > Without a hair filter from the start all etg specimens are > invalid!! > > The fur is going to fly!!!DD2> >> > Get easy, one-click access to your favorites. Make your homepage. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2007 Report Share Posted December 4, 2007 I have changed since experiencing the "wrath" of EtG. I never assume anyone is guilty based on "Scientific" evidence anymore. I know now that science is only as good as those who interpret it, and in most cases there is alot of money at stake if a particular test is found not to be reliable. Some people would rather continue using a test they know is inaccurate than risk losing money. Sad. -------------- Original message -------------- From: Marsha Dienelt <marshadienelt@...> No kidding, Joy, about others not getting/believing it re: EtG. And why should they, it's so damn absurd?! It's like we have our own little Secret Society. I never envisioned anything of the likes of this when I started recovery over 5 yrs ago. Thank goodness we have each other !!! Marshajoyous1_1210 <joyous1_1210 > wrote: oh.......I thought this was a joke at first too, but then it hit me........I almost forgot that NOTHING surprises me when it comes to EtG testing and the use and ABUSE of this ridiculous test....thanks for sharing the info! You know no one on the "outside" would ever believe this stuff if they came across it nonchalantly in a magazine or newspaper!thanks! joy:)> >> > Helander has published new research showing that pubic hair > contains a > > much higher concentration of etg than social drinkers head hair. I > > would therefore think if you were a hairy person you would be more > > likely to have higher concetrations of etg in your marital > appendages > > even if you shaved. And how do we keep hair out of our specimens? > > Without a hair filter from the start all etg specimens are > invalid!! > > The fur is going to fly!!!DD2> >> Be a better pen pal. Text or chat with friends inside . See how. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2007 Report Share Posted December 4, 2007 Congrats!! I long for the day. ---- Marsha Dienelt <marshadienelt@...> wrote: > Never did do hair screening, Henny--- & thanks to my HP I am done with monitoring finally!!! > Marsha > > arein862@... wrote: > is anyone actually doing hair analysis for etg in their monitoring program? > ---- Henny <hennipen14@...> wrote: > > Dr. Dan ~ At first I thought you were joking, poking some clever fun > > at EtG testing. I should have known better. You were serious!!! > > > > Forensic Sci Int. 2007 Nov 8 > > Ethyl glucuronide: Unusual distribution between head hair and pubic > > hair. > > Kintz P, Villain M, Vallet E, Etter M, Salquebre G, Cirimele V. > > Laboratoire ChemTox, 3 rue Grüninger, 67400 Illkirch, France. > > > > " Ethyl glucuronide (EtG) is a minor metabolite of ethanol that can be > > detected in hair. In some specific situations, head hair can be > > missing, and therefore, alternative anatomical locations of hair are > > of interest. In this study, paired hair specimens (head hair and > > pubic hair) from eight social drinkers were analyzed for EtG. Each > > sample was decontaminated by two dichloromethane bathes (5ml) for > > 2min. After cutting into small pieces, about 50mg of hair was > > incubated in 2ml water in the presence of 10ng of EtG-d(5), used as > > internal standard and submitted to ultra-sonication for 2h. The > > aqueous phase was extracted by SPE using Oasis MAX columns. The hair > > extract was separated on an ACQUITY BEH HILIC column using a gradient > > of acetonitrile and formate buffer. Detection was based on two > > daughter ions: transitions m/z 221-85 and 75 and m/z 226-75 for EtG > > and the IS, respectively. This laboratory is using a positive cut-off > > at 50pg/mg. All eight head hair specimens were negative for EtG at a > > limit of quantitation fixed at 10pg/mg. Surprisingly, EtG was > > identified at high concentrations in pubic hair, in the range 12- > > 1370pg/mg. It appears, therefore, that it is not possible to document > > the drinking status of a subject by simply switching from head hair > > to pubic hair. " PMID: 17997064 > > > > " The fur is going to fly " ...I love it! > > > > Henny > > > > > > > > > > > > Helander has published new research showing that pubic hair > > contains a > > > much higher concentration of etg than social drinkers head hair. I > > > would therefore think if you were a hairy person you would be more > > > likely to have higher concetrations of etg in your marital > > appendages > > > even if you shaved. And how do we keep hair out of our specimens? > > > Without a hair filter from the start all etg specimens are > > invalid!! > > > The fur is going to fly!!!DD2 > > > > > > > > > > > > > > --------------------------------- > Get easy, one-click access to your favorites. Make your homepage. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 5, 2007 Report Share Posted December 5, 2007 I have to laugh at this latest finding. When I first tested positive, my family, in an effort to help me figure out why, came up with some very "strange" possibilities. My brother in law, thought that maybe my boyfriend had a beer or two prior to an "encounter" and that somehow made me positive. He suggested that maybe condoms would be a good idea, he even went as far as to buy some to see if they were coated with any form of alcohol! Guess his focus on that "area" was not so far off base after all. I wish those responsible for this test spent half as much time as we and our friends and family have trying to figure it all out!! -------------- Original message -------------- From: <arein862@...> Congrats!! I long for the day.---- Marsha Dienelt <marshadienelt > wrote: > Never did do hair screening, Henny--- & thanks to my HP I am done with monitoring finally!!!> Marsha > > arein862tx (DOT) rr.com wrote:> is anyone actually doing hair analysis for etg in their monitoring program?> ---- Henny <hennipen14 > wrote: > > Dr. Dan ~ At first I thought you were joking, poking some clever fun > > at EtG testing. I should have known better. You were serious!!! > > > > Forensic Sci Int. 2007 Nov 8 > > Ethyl glucuronide: Unusual distribution between head hair and pubic > > hair.> > Kintz P, Villain M, Vallet E, Etter M, Salquebre G, Cirimele V.> > Laboratoire ChemTox, 3 rue Grüninger, 67400 Illkirch, France.> > > > "Ethyl glucuronide (EtG) is a minor metabolite of ethanol that can be > > detected in hair. In some specific situations, head hair can be > > missing, and therefore, alternative anatomical locations of hair are > > of interest. In this study, paired hair specimens (head hair and > > pubic hair) from eight social drinkers were analyzed for EtG. Each > > sample was decontaminated by two dichloromethane bathes (5ml) for > > 2min. After cutting into small pieces, about 50mg of hair was > > incubated in 2ml water in the presence of 10ng of EtG-d(5), used as > > internal standard and submitted to ultra-sonication for 2h. The > > aqueous phase was extracted by SPE using Oasis MAX columns. The hair > > extract was separated on an ACQUITY BEH HILIC column using a gradient > > of acetonitrile and formate buffer. Detection was based o n two > > daughter ions: transitions m/z 221-85 and 75 and m/z 226-75 for EtG > > and the IS, respectively. This laboratory is using a positive cut-off > > at 50pg/mg. All eight head hair specimens were negative for EtG at a > > limit of quantitation fixed at 10pg/mg. Surprisingly, EtG was > > identified at high concentrations in pubic hair, in the range 12-> > 1370pg/mg. It appears, therefore, that it is not possible to document > > the drinking status of a subject by simply switching from head hair > > to pubic hair." PMID: 17997064> > > > "The fur is going to fly"...I love it!> > > > Henny> > > > > > > > >> > > Helander has published new research showing that pubic hair > > contains a > > > much higher concentration of etg than social drinkers head hair. I > > > would therefore think if you were a hairy person you would be more > > > likely to have higher concetrations of etg in your marital > > appendages > > > even if you shaved. And how do we keep hair out of our specimens? > > > Without a hair filter from the start all etg specimens are > > invalid!! > > > The fur is going to fly!!!DD2> > >> > > > > > > > > > > ---------------------------------> Get easy, one-click access to your favorites. Make your homepage. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 16, 2009 Report Share Posted March 16, 2009 Oncostatin M May Be Promising Drug For Treating Viral Hepatitis And Liver Cancer ScienceDaily (Feb. 18, 2009) — The Department of Gene Therapy and Hepatology of the Center for Applied Medical Research (CIMA) of the University of Navarra has identified a molecule as possibly effective for improving the treatment of chronic hepatitis and liver cancer. This research, coordinated by the doctors Jesús Prieto, Esther Larrea, Pablo Sarobe, Iranzu González and Aldabe, has been published in the Journal of Virology. When organisms suffer a viral infection, dendritic cells (natural proteins produced as a response of the immune system to foreign agents) release type I interferon. The researchers of the CIMA observed that dendritic cells also produced Oncostatin M. "What was remarkable was the evidence that Oncostatin improved the effect of interferon in inhibiting the replication of viruses as well as noticeably increasing the antiviral response of the immune system", said Dr. Jesús Prieto. These findings suggest that the combination of both molecules may be useful for treating viral diseases that do not respond to isolated treatment with interferon, something which occurs in patients with viral B or C chronic hepatitis. "In addition, it is possible that this combination could be effective for designing strategies against different tumor processes in which conventional therapy is unsuccessful", suggested Dr. Prieto. The Center for Applied Medical Research has patented this therapeutic formula, based on the combination of type I interfon and oncostatin for oncology treatment and antiviral therapy. Its development for clinical application is being carried out by the Spanish biotechnology company Digna Biotech. Quote Link to comment Share on other sites More sharing options...
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