Fw: Painkillers: Tylenol better than Ibuprofen?

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Painkillers: Tylenol better than Ibuprofen?TITLE: Ibuprofen-induced hepatotoxicity in patients with chronic hepatitisC: a case series.Hepatitis C is a common chronic infection. Nonsteroidal anti-inflammatorydrugs are commonly ingested both over-the-counter and by prescription. Thiscase report describes three cases where ibuprofen use leads to a marked risein hepatic transaminases with one case repeating on rechallenge. These casessupport the recommendation of acetaminophen over nonsteroidalantiinflammatory drug use in patients with chronic hepatitis C.AUTHOR: Riley TR 3rd, JP, Penn State Geisinger Health System, TheMilton S. Hershey Medical Center, The Pennsylvania State University,Department of Medicine, Hershey 17033-0850, USA. SOURCE: Am J Gastroenterol1998 Sep;93(9):1563-1565----------------OTC Medications Can Cause Problems For Hepatitis C PatientsHERSHEY, PA -- Sept. 16, 1998 -- Patients with chronic hepatitis C oftentake the over-the-counter non-steroidal drug Ibuprofen, otherwise known asMotrin or Advil, to combat joint pain that often accompanies the disease.However, even a low dose could lead to unsuspecting liver damage."Patients frequently suffer from joint pain. Often, even physicians willprescribe ibuprofen when they should prescribe Tylenol," explained Riley, III, M.D., assistant professor of medicine at Penn State's College ofMedicine. "The correct recommendation to help the patient is a low dose ofTylenol, about two grams per day. That means the patient can take one extrastrength Tylenol -- 500 mg -- every six hours or take two every 12 hours."Riley and his colleagues describe three cases in an article published inthis month's issue of the American Journal of Gastroenterology.In each of these three cases the patients have hepatitis C and tookover-the-counter ibuprofen. After doing so they all had a flare-up of theirhepatitis."Many physicians don't want to prescribe Tylenol because it has a reputationof causing liver damage. As long as it is prescribed in the low doses wehave discussed it is definitely the best treatment," explained Riley, who isalso the medical director for the liver transplant program at The Milton S.Hershey Medical Center of the Penn State Geisinger Health System.He said where patients with chronic hepatitis C usually have mild elevationsin their liver enzymes in the blood, after taking the over-the-counterIbuprofen these patients experience a 10-fold rise in their enzymes,suggesting significant liver injury.He added that if too much medication is taken the patient risks speeding upthe process of going from chronic hepatitis to cirrhosis of the liver. Rileysaid that about four million Americans are infected with hepatitis C."Many patients can live with hepatitis for perhaps 50 years. However, if toomuch of the wrong medication is taken or if the patient consumes a lot ofalcohol, the process from hepatitis to cirrhosis can speed up," Riley said.This articles focuses on three cases. Riley said further study is needed ofa large group of patients with hepatitis C to determine perhaps an evenbetter approach to this growing problem.

[Guest guest]

Second message.

Painkillers: Tylenol better than Ibuprofen?

TITLE: Ibuprofen-induced hepatotoxicity in patients with chronic

hepatitis

C: a case series.

Hepatitis C is a common chronic infection. Nonsteroidal anti-

inflammatory

drugs are commonly ingested both over-the-counter and by

prescription. This

case report describes three cases where ibuprofen use leads to a

marked rise

in hepatic transaminases with one case repeating on rechallenge.

These cases

support the recommendation of acetaminophen over nonsteroidal

antiinflammatory drug use in patients with chronic hepatitis C.

AUTHOR: Riley TR 3rd, JP, Penn State Geisinger Health System,

The

Milton S. Hershey Medical Center, The Pennsylvania State University,

Department of Medicine, Hershey 17033-0850, USA. SOURCE: Am J

Gastroenterol

1998 Sep;93(9):1563-1565

----------------

OTC Medications Can Cause Problems For Hepatitis C Patients

HERSHEY, PA -- Sept. 16, 1998 -- Patients with chronic hepatitis C

often

take the over-the-counter non-steroidal drug Ibuprofen, otherwise

known as

Motrin or Advil, to combat joint pain that often accompanies the

disease.

However, even a low dose could lead to unsuspecting liver damage.

" Patients frequently suffer from joint pain. Often, even physicians

will

prescribe ibuprofen when they should prescribe Tylenol, " explained

Riley, III, M.D., assistant professor of medicine at Penn State's

College of

Medicine. " The correct recommendation to help the patient is a low

dose of

Tylenol, about two grams per day. That means the patient can take

one extra

strength Tylenol -- 500 mg -- every six hours or take two every 12

hours. "

Riley and his colleagues describe three cases in an article

published in

this month's issue of the American Journal of Gastroenterology.

In each of these three cases the patients have hepatitis C and took

over-the-counter ibuprofen. After doing so they all had a flare-up

of their

hepatitis.

" Many physicians don't want to prescribe Tylenol because it has a

reputation

of causing liver damage. As long as it is prescribed in the low

doses we

have discussed it is definitely the best treatment, " explained

Riley, who is

also the medical director for the liver transplant program at The

Milton S.

Hershey Medical Center of the Penn State Geisinger Health System.

He said where patients with chronic hepatitis C usually have mild

elevations

in their liver enzymes in the blood, after taking the over-the-

counter

Ibuprofen these patients experience a 10-fold rise in their enzymes,

suggesting significant liver injury.

He added that if too much medication is taken the patient risks

speeding up

the process of going from chronic hepatitis to cirrhosis of the

liver. Riley

said that about four million Americans are infected with hepatitis C.

" Many patients can live with hepatitis for perhaps 50 years.

However, if too

much of the wrong medication is taken or if the patient consumes a

lot of

alcohol, the process from hepatitis to cirrhosis can speed up, "

Riley said.

This articles focuses on three cases. Riley said further study is

needed of

a large group of patients with hepatitis C to determine perhaps an

even

better approach to this growing problem.

[Guest guest]

This is what I'm talking about, thank you,

Donna Gail

>

>

> Painkillers: Tylenol better than Ibuprofen?

>

>

> TITLE: Ibuprofen-induced hepatotoxicity in patients with chronic

> hepatitis

> C: a case series.

>

> Hepatitis C is a common chronic infection. Nonsteroidal anti-

> inflammatory

> drugs are commonly ingested both over-the-counter and by

> prescription. This

> case report describes three cases where ibuprofen use leads to a

> marked rise

> in hepatic transaminases with one case repeating on rechallenge.

> These cases

> support the recommendation of acetaminophen over nonsteroidal

> antiinflammatory drug use in patients with chronic hepatitis C.

>

> AUTHOR: Riley TR 3rd, JP, Penn State Geisinger Health

System,

> The

> Milton S. Hershey Medical Center, The Pennsylvania State

University,

> Department of Medicine, Hershey 17033-0850, USA. SOURCE: Am J

> Gastroenterol

> 1998 Sep;93(9):1563-1565

> ----------------

> OTC Medications Can Cause Problems For Hepatitis C Patients

>

> HERSHEY, PA -- Sept. 16, 1998 -- Patients with chronic hepatitis C

> often

> take the over-the-counter non-steroidal drug Ibuprofen, otherwise

> known as

> Motrin or Advil, to combat joint pain that often accompanies the

> disease.

> However, even a low dose could lead to unsuspecting liver damage.

>

> " Patients frequently suffer from joint pain. Often, even

physicians

> will

> prescribe ibuprofen when they should prescribe Tylenol, " explained

>

> Riley, III, M.D., assistant professor of medicine at Penn State's

> College of

> Medicine. " The correct recommendation to help the patient is a low

> dose of

> Tylenol, about two grams per day. That means the patient can take

> one extra

> strength Tylenol -- 500 mg -- every six hours or take two every 12

> hours. "

>

> Riley and his colleagues describe three cases in an article

> published in

> this month's issue of the American Journal of Gastroenterology.

>

> In each of these three cases the patients have hepatitis C and took

> over-the-counter ibuprofen. After doing so they all had a flare-up

> of their

> hepatitis.

>

> " Many physicians don't want to prescribe Tylenol because it has a

> reputation

> of causing liver damage. As long as it is prescribed in the low

> doses we

> have discussed it is definitely the best treatment, " explained

> Riley, who is

> also the medical director for the liver transplant program at The

> Milton S.

> Hershey Medical Center of the Penn State Geisinger Health System.

>

> He said where patients with chronic hepatitis C usually have mild

> elevations

> in their liver enzymes in the blood, after taking the over-the-

> counter

> Ibuprofen these patients experience a 10-fold rise in their

enzymes,

> suggesting significant liver injury.

>

> He added that if too much medication is taken the patient risks

> speeding up

> the process of going from chronic hepatitis to cirrhosis of the

> liver. Riley

> said that about four million Americans are infected with hepatitis

C.

>

> " Many patients can live with hepatitis for perhaps 50 years.

> However, if too

> much of the wrong medication is taken or if the patient consumes a

> lot of

> alcohol, the process from hepatitis to cirrhosis can speed up, "

> Riley said.

>

> This articles focuses on three cases. Riley said further study is

> needed of

> a large group of patients with hepatitis C to determine perhaps an

> even

> better approach to this growing problem.

>

>

>

>

[Guest guest]

seems like we are all in same groups..... LOL....... thanks, sally

--- hdhepper1 <grisley4@...> wrote:

> Second message.

>

>

>

>

> Painkillers: Tylenol better than Ibuprofen?

>

>

> TITLE: Ibuprofen-induced hepatotoxicity in patients with chronic

> hepatitis

> C: a case series.

>

> Hepatitis C is a common chronic infection. Nonsteroidal anti-

> inflammatory

> drugs are commonly ingested both over-the-counter and by

> prescription. This

> case report describes three cases where ibuprofen use leads to a

> marked rise

> in hepatic transaminases with one case repeating on rechallenge.

> These cases

> support the recommendation of acetaminophen over nonsteroidal

> antiinflammatory drug use in patients with chronic hepatitis C.

>

> AUTHOR: Riley TR 3rd, JP, Penn State Geisinger Health System,

> The

> Milton S. Hershey Medical Center, The Pennsylvania State University,

> Department of Medicine, Hershey 17033-0850, USA. SOURCE: Am J

> Gastroenterol

> 1998 Sep;93(9):1563-1565

> ----------------

> OTC Medications Can Cause Problems For Hepatitis C Patients

>

> HERSHEY, PA -- Sept. 16, 1998 -- Patients with chronic hepatitis C

> often

> take the over-the-counter non-steroidal drug Ibuprofen, otherwise

> known as

> Motrin or Advil, to combat joint pain that often accompanies the

> disease.

> However, even a low dose could lead to unsuspecting liver damage.

>

> " Patients frequently suffer from joint pain. Often, even physicians

> will

> prescribe ibuprofen when they should prescribe Tylenol, " explained

>

> Riley, III, M.D., assistant professor of medicine at Penn State's

> College of

> Medicine. " The correct recommendation to help the patient is a low

> dose of

> Tylenol, about two grams per day. That means the patient can take

> one extra

> strength Tylenol -- 500 mg -- every six hours or take two every 12

> hours. "

>

> Riley and his colleagues describe three cases in an article

> published in

> this month's issue of the American Journal of Gastroenterology.

>

> In each of these three cases the patients have hepatitis C and took

> over-the-counter ibuprofen. After doing so they all had a flare-up

> of their

> hepatitis.

>

> " Many physicians don't want to prescribe Tylenol because it has a

> reputation

> of causing liver damage. As long as it is prescribed in the low

> doses we

> have discussed it is definitely the best treatment, " explained

> Riley, who is

> also the medical director for the liver transplant program at The

> Milton S.

> Hershey Medical Center of the Penn State Geisinger Health System.

>

> He said where patients with chronic hepatitis C usually have mild

> elevations

> in their liver enzymes in the blood, after taking the over-the-

> counter

> Ibuprofen these patients experience a 10-fold rise in their enzymes,

> suggesting significant liver injury.

>

> He added that if too much medication is taken the patient risks

> speeding up

> the process of going from chronic hepatitis to cirrhosis of the

> liver. Riley

> said that about four million Americans are infected with hepatitis C.

>

> " Many patients can live with hepatitis for perhaps 50 years.

> However, if too

> much of the wrong medication is taken or if the patient consumes a

> lot of

> alcohol, the process from hepatitis to cirrhosis can speed up, "

> Riley said.

>

> This articles focuses on three cases. Riley said further study is

> needed of

> a large group of patients with hepatitis C to determine perhaps an

> even

> better approach to this growing problem.

>

>

>

>