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Oral Interferon

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Hi Jodi --

I talked to a patient of Dr. Salvato's who said that the combination of oral

interferon and glutathione had raised her natural killer cell count back to

normal. My count was normal to begin with.

You might also consider giving your pharmacist the number of Catchings

Pharmacy -- 800-356-1620 -- so he can find out how mixes the

stuff there. His dosages are pretty accurate. I've heard that interferon

tends to clump up when you dilute it, so using Salvato's method, where you

make one big bottle of the stuff and then withdraw individual doses as you

take them, might cause the dosages to be inaccurate.

Good luck, and thanks for sharing!

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> I talked to a patient of Dr. Salvato's who said that the combination of oral

> interferon and glutathione had raised her natural killer cell count back to

> normal. My count was normal to begin with.

The *COUNT* is virtually meaningless. Its the *FUNCTION* that matters.

There are many people with terminal cancer, on death's doorstep with

normal NK counts, but their NK function is undetectable. It doesn't

matter how many NK cells you have if they are " turned off " and are not

doing their job. My NK count was perfectally " normal " , my NK function

was undetectable. I was suprised that as " progressive " as dr. Bihari

is, he does an NK count instead of NK function. This is a pointless

waste of money.

Patti

--

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  • 3 months later...
Guest guest

Brown wrote:

> From: Brown <pbrown@...>

>

> Picked up my oral interferon alpha lozenges today. Took 1/2 of one about

> 2:15 p.m.[approx 75 I.U.] Noticed phlegm starting to trickle down my

> throat and throat a bit tender within 20 minutes. Will let you know how

> it goes.

> Brown

Congratulations , hope the interferon works for you! Do you have CFS

and/or FMS??? How long have you been ill??? Do you know if the lozenges are

available to us here in the US yet? How

does the stuff taste?????

Good luck to you and keep us posted on your progress!

Marcia

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Hi ,

I certainly do wish you well on the interferon and hope it helps you

tremendously. Actually, I wanted to try it, too, and when I went to see

Cheney (my CFIDS doc) in April, I asked him about it. But he didn't

seem to support the idea. Maybe because he suspects that I'm in Phase

II of CFIDS and I need to have a different treatment approach or

something, I don't know... At any rate, he started talking about the

difference between oral interferon and (dare I mention the word?)

ampligen. When I asked him exactly what WAS the difference was between

the two medicines, Cheney said that interferon worked like a " drug " and

had an effect on everything and ampligen just worked on a problem if it

to " be fixed. " He used the analogy of blood pressure medicine. He said

interferon is like blood pressure medicine. A blood pressure pill lowers

your blood pressure whether you need for your blood pressure to be

lowered or not. Ampligen, on the other hand, would be a type of " blood

pressure pill " that would just lower your blood pressure if you needed

to have your blood pressure lowered. I think that is why some people

on interferon have gotten sick on Interferon. It does everything,

instead of just regulating the defective RNase-L enzyme. However, it

HAS worked wonderfully for some of the folks on this list and hopefully

it'll do great things for you, too! Once again, good luck! Do let us

know how you progress. I'd like to tell Cheney.

Brown wrote:

>

> From: Brown <pbrown@...>

>

> Picked up my oral interferon alpha lozenges today. Took 1/2 of one about

> 2:15 p.m.[approx 75 I.U.] Noticed phlegm starting to trickle down my

> throat and throat a bit tender within 20 minutes. Will let you know how

> it goes.

> Brown

>

> ---------------------------

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This I don't know about, as I didn't ask Cheney about gamma globulin.

But in his DFW Seminar he showed slides of people on whom he had run

ampligen tests and you could actually SEE the defective RNase-L enzyme

being corrected. Actually, it was quite interesting to see. Please

note here that I am neither pro or con on the Ampligen issue. In fact,

right now I am taking Immunocal.

SWNGDABOAT@... wrote:

>

> From: SWNGDABOAT@...

>

> My MD read through all the Ampligen literature and concluded that Ampligen is

> just " a second generation gamma globulin. "

>

> ---------------------------

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Its my understanding that Ampligen is a second generation INTERFERON, not gamma

globulin.

Marcia

allan moore wrote:

> From: allan moore <afmoore1@...>

>

> This I don't know about, as I didn't ask Cheney about gamma globulin.

> But in his DFW Seminar he showed slides of people on whom he had run

> ampligen tests and you could actually SEE the defective RNase-L enzyme

> being corrected. Actually, it was quite interesting to see. Please

> note here that I am neither pro or con on the Ampligen issue. In fact,

> right now I am taking Immunocal.

>

> SWNGDABOAT@... wrote:

> >

> > From: SWNGDABOAT@...

> >

> > My MD read through all the Ampligen literature and concluded that Ampligen

is

> > just " a second generation gamma globulin. "

> >

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  • 11 months later...
Guest guest

Sorry I have not noticed previous posts - how does one get oral interferon -

what do you " suggest " to your doc' to get it, and who is particularly suited

for it - any PWC? I have read about it, but seem to remember it had some

risks? Anyone help with this, thanks?

M-

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  • 5 years later...

Amarillo Biosciences to Provide Oral Interferon for MD Clinical Trial in Patients With Bone Marrow Disorders

Enrollment at MD Cancer Center Open

AMARILLO, TX -- (MARKET WIRE) -- 09/22/2005 -- Amarillo Biosciences, Inc. (ABI) (OTC BB: AMAR) today announced that a study to test low dose oral interferon alpha in forty patients with rare bone marrow proliferative disorders is now open to enrollment. Amarillo Biosciences filed the Investigational New Drug Application with the FDA, and, in conjunction with principal investigator Srdan Verstovsek, MD, PhD, Assistant Professor, Myeloproliferative Disorders Program Leader, University of Texas, MD Cancer Center, Houston, Texas, helped to develop the protocol for the clinical trial. In addition, Amarillo Biosciences will provide the low dose oral interferon that will be used in the study. Twenty patients, each with either polycythemia vera (PV) or primary thrombocythemia (ET), will be given low dose oral interferon alpha daily as a treatment to relieve the signs and symptoms associated with these disorders. This study is open to patients not previously exposed to interferon preparations. Potential participants should not be currently taking other medications to control their blood cell count. PV and ET are stem cell disorders considered to be incurable. Treatment is directed at reducing morbidity and preventing life-threatening complications. The clinical course of both ET and PV are characterized by vasomotor disturbances (headaches, dizziness), acral dysesthesia (impaired sensations in limbs, fingers, ears), erythromelalgia (diffused redness and atrophy of skin on legs), visual symptoms, thrombohemorrahagic (inappropriate clotting) events, and the risk of transformation into acute myeloid leukemia (AML) or fibrosis of the bone marrow (myelofibrosis). Treatment efforts in ET strive to reduce clotting events in patients at high-risk for thrombosis without increasing the intrinsically low risk of developing leukemia. All patients with PV require phlebotomy (drawing blood), with the goal of reducing hematocrit levels (the concentration of red blood cells). This maneuver prolongs survival by decreasing the risk of thrombosis. The goal of therapy in PV is not only to prevent thrombosis, but also to reduce the risk of transformation into AML or myelofibrosis. PV and ET patients interested in enrollment should contact Srdan Verstovsek, MD, PhD, Assistant Professor, Myeloproliferative Disorders Program Leader, University of Texas, MD Cancer Center, Houston, Texas at (713) 792-7305. About Amarillo Biosciences, Inc. Amarillo Biosciences, Inc., is a U.S. biotechnology firm operating in global partnership with the Hayashibara Group, which also holds 20.6% of Amarillo Biosciences shares and has provided over $17.8 million in loans, grants and equity investments. The Company's primary focus is extensive and ongoing R & D into the use of low-dose, orally administered interferon as a treatment for a variety of conditions, including Sjogren's syndrome, Behcet's disease, and opportunistic infections in patients who are HIV positive. In its 20-year history, ABI has invested nearly $37 million to establish oral interferon as a therapeutic agent. The overwhelming majority of those funds were invested in clinical trials in an effort to achieve FDA approval for interferon. Additional information is available on the ABI web site at http://www.amarbio.com/. Except for the historical information contained herein, the matters discussed in this news release are forward-looking statements that involve risks and uncertainties, including uncertainties related to product development, uncertainties related to the need for regulatory and other government approvals, dependence on proprietary technology, uncertainty of market acceptance of oral interferon or the Company's other product candidates and other risks detailed from time to time in the Company's filings with the Securities and Exchange Commission. In particular, see "Item 1. Description of Business" of the Company's Form 10-KSB for the year ended December 31, 2004.

Investor Relations:

Philippe Niemetz

WPH Consultants, Ltd.

Tel: 800-477-7570

Tel: 212-344-6464

Fax: 212-618-1276

e-mail: Email Contact

ph M. Cummins, DVM, PhD

Amarillo Biosciences, Inc.

Tel: 806-376-1741 x 13

Fax: 806-376-9301

e-mail: Email Contact

SOURCE: Amarillo Biosciences, Inc.

http://www.marketwire.com/mw/release_html_b1?release_id=95991

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