Guest guest Posted September 6, 2001 Report Share Posted September 6, 2001 Thanks again Claudine. This answered my unasked question....I was taking 2 tylenol 3s a day for pain. My doc cut me down to 1 tylenol 3 a day....and I was leary of even taking that. But I feel better about it now. You are a constant source of excellent info....your file on my compi is getting bigger everyday. Hugggs for all the work you put into this to inform others. Carol claudine intexas wrote: > from Dr. Palmer's book > > Painkillers and the Liver > > " Which type of painkiller is safer for my liver - > acetaminophen (Tylenol), > or nonsteroidal anti-inflammatories (such as > Aspirin,or Motrin)? " > > Acetaminophen (APAP or Tylenol) is a medication used > to control pain > (known as an analgesic) and fever (known as an > antipyretic). It does this > without producing the stomach discomfort often > experienced with aspirin > and other nonsteroidal anti-inflammatories (NSAIDs). > This capability has > caused acetaminophen to become a very popular > alternative to NSAIDs. In > small doses (i.e. less than four grams per day, or > eight pills taken over > a twenty-four hour period of time) acetaminophen is > quite safe for the > liver. (Note: each acetaminophen tablet or pill > typically contains 500mg > of acetaminophen). In fact, acetaminophen is the > recommended medication > for relieving minor aches, pains and headaches from > any cause in > individuals with liver disease. > > However, when taken in excessive quantities or when > combined with alcohol, > acetaminophen may cause death due to liver failure. > In fact, an overdose > of acetaminophen is one of the most common causes of > liver failure, as > well as the most common cause of drug-induced liver > disease in the United > States. And, after acetaminophen became readily > available in 1960 as an > over-the- counter medication, it became one of the > most popular > instrumentality's for attempting suicide. > > For liver injury to occur, acetaminophen must > generally be consumed in a > quantity exceeding fifteen grams within a short > period of time, such as in > a single dose. Although uncommon, an ingestion of > between seven to ten > grams at one time may also cause liver damage. The > consumption of alcohol > in conjunction with acetaminophen significantly > increases the likelihood > that an individual will incur severe liver damage. > Therefore, individuals > who consume alcohol on a regular basis should > probably limit acetaminophen > intake to a maximum of one to two grams per day (i.e. > two to four pills > within a twenty-four hour period). Still, the best > advise for individuals > with liver disease is to totally abstain from > alcohol. > > Individuals should take special note that > acetaminophen is also an active > ingredient in more than two hundred other > medications, including Nyquil > and Anacin 3. So, it is essential to carefully read > the labels of all > over-the- counter medications carefully. Other > commonly used medications > such as omeprazole (Prilosec), phenytoin ( Dilantin), > and isoniazid (INH) > may increase the risk of liver injury caused by > acetaminophen. It is > always in the liver patient's best interests to > consult with his or her > hepatologist prior to taking any medication. > > Acetylsalicylic acid (Aspirin) and other NSAIDs are > drugs which are widely > used for their anti-inflammatory and analgesic > effects. They also have the > potential to cause drug-induced liver disease. In > fact, many NSAIDs have > been withdrawn from the market due to their harmful > effects on the liver > (known as hepatotoxicity). All NSAIDs have the > potential to cause liver > injury. However, some NSAIDs are more hepatotoxic > than others. The NSAIDs > which are presently on the market, yet are frequently > associated with > liver injury are: aspirin (ASA), diclofenac > (Voltaren), and sulindac > (Clinoril). Therefore, individuals with liver disease > should avoid using > these NSAIDs. Older women seem to be particularly > susceptible to the > hepatotoxicity of NSAIDs, and are best advised to > avoid NSAIDs altogether. > Individuals who have developed complications of > cirrhosis, (known as > decompensated cirrhosis), such as ascites > (accumulation of fluid in the > abdomen) or bleeding esophageal varices (enlarged > blood vessels in the > esophagus), are at increased risk for kidney injury > due to NSAIDs. Since > this may lead to both liver and kidney failure, known > as hepatorenal > syndrome, individuals with advanced liver disease are > best advised to > totally avoid all NSAIDs. > > In conclusion, acetaminophen taken in moderate > dosages is generally the > safer choice for the relief of minor aches and pains > occurring in > individuals with any type of hepatitis or liver > disease. > > Excerpted from " Dr. Palmer's Guide To > Hepatitis and Liver Disease " > © Copyright Palmer, MD 1999. > > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted September 6, 2001 Report Share Posted September 6, 2001 Thanks again Claudine. This answered my unasked question....I was taking 2 tylenol 3s a day for pain. My doc cut me down to 1 tylenol 3 a day....and I was leary of even taking that. But I feel better about it now. You are a constant source of excellent info....your file on my compi is getting bigger everyday. Hugggs for all the work you put into this to inform others. Carol claudine intexas wrote: > from Dr. Palmer's book > > Painkillers and the Liver > > " Which type of painkiller is safer for my liver - > acetaminophen (Tylenol), > or nonsteroidal anti-inflammatories (such as > Aspirin,or Motrin)? " > > Acetaminophen (APAP or Tylenol) is a medication used > to control pain > (known as an analgesic) and fever (known as an > antipyretic). It does this > without producing the stomach discomfort often > experienced with aspirin > and other nonsteroidal anti-inflammatories (NSAIDs). > This capability has > caused acetaminophen to become a very popular > alternative to NSAIDs. In > small doses (i.e. less than four grams per day, or > eight pills taken over > a twenty-four hour period of time) acetaminophen is > quite safe for the > liver. (Note: each acetaminophen tablet or pill > typically contains 500mg > of acetaminophen). In fact, acetaminophen is the > recommended medication > for relieving minor aches, pains and headaches from > any cause in > individuals with liver disease. > > However, when taken in excessive quantities or when > combined with alcohol, > acetaminophen may cause death due to liver failure. > In fact, an overdose > of acetaminophen is one of the most common causes of > liver failure, as > well as the most common cause of drug-induced liver > disease in the United > States. And, after acetaminophen became readily > available in 1960 as an > over-the- counter medication, it became one of the > most popular > instrumentality's for attempting suicide. > > For liver injury to occur, acetaminophen must > generally be consumed in a > quantity exceeding fifteen grams within a short > period of time, such as in > a single dose. Although uncommon, an ingestion of > between seven to ten > grams at one time may also cause liver damage. The > consumption of alcohol > in conjunction with acetaminophen significantly > increases the likelihood > that an individual will incur severe liver damage. > Therefore, individuals > who consume alcohol on a regular basis should > probably limit acetaminophen > intake to a maximum of one to two grams per day (i.e. > two to four pills > within a twenty-four hour period). Still, the best > advise for individuals > with liver disease is to totally abstain from > alcohol. > > Individuals should take special note that > acetaminophen is also an active > ingredient in more than two hundred other > medications, including Nyquil > and Anacin 3. So, it is essential to carefully read > the labels of all > over-the- counter medications carefully. Other > commonly used medications > such as omeprazole (Prilosec), phenytoin ( Dilantin), > and isoniazid (INH) > may increase the risk of liver injury caused by > acetaminophen. It is > always in the liver patient's best interests to > consult with his or her > hepatologist prior to taking any medication. > > Acetylsalicylic acid (Aspirin) and other NSAIDs are > drugs which are widely > used for their anti-inflammatory and analgesic > effects. They also have the > potential to cause drug-induced liver disease. In > fact, many NSAIDs have > been withdrawn from the market due to their harmful > effects on the liver > (known as hepatotoxicity). All NSAIDs have the > potential to cause liver > injury. However, some NSAIDs are more hepatotoxic > than others. The NSAIDs > which are presently on the market, yet are frequently > associated with > liver injury are: aspirin (ASA), diclofenac > (Voltaren), and sulindac > (Clinoril). Therefore, individuals with liver disease > should avoid using > these NSAIDs. Older women seem to be particularly > susceptible to the > hepatotoxicity of NSAIDs, and are best advised to > avoid NSAIDs altogether. > Individuals who have developed complications of > cirrhosis, (known as > decompensated cirrhosis), such as ascites > (accumulation of fluid in the > abdomen) or bleeding esophageal varices (enlarged > blood vessels in the > esophagus), are at increased risk for kidney injury > due to NSAIDs. Since > this may lead to both liver and kidney failure, known > as hepatorenal > syndrome, individuals with advanced liver disease are > best advised to > totally avoid all NSAIDs. > > In conclusion, acetaminophen taken in moderate > dosages is generally the > safer choice for the relief of minor aches and pains > occurring in > individuals with any type of hepatitis or liver > disease. > > Excerpted from " Dr. Palmer's Guide To > Hepatitis and Liver Disease " > © Copyright Palmer, MD 1999. > > __________________________________________________ > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 20, 2002 Report Share Posted June 20, 2002 Excerpted from " Dr. Palmer's Guide To Hepatitis and Liver Disease " © Copyright Palmer, MD 1999. Painkillers and the Liver " Which type of painkiller is safer for my liver - acetaminophen (Tylenol), or nonsteroidal anti-inflammatories (such as Aspirin,or Motrin)? " Acetaminophen (APAP or Tylenol) is a medication used to control pain (known as an analgesic) and fever (known as an antipyretic). It does this without producing the stomach discomfort often experienced with aspirin and other nonsteroidal anti-inflammatories (NSAIDs). This capability has caused acetaminophen to become a very popular alternative to NSAIDs. In small doses (i.e. less than four grams per day, or eight pills taken over a twenty-four hour period of time) acetaminophen is quite safe for the liver. (Note: each acetaminophen tablet or pill typically contains 500mg of acetaminophen). In fact, acetaminophen is the recommended medication for relieving minor aches, pains and headaches from any cause in individuals with liver disease. However, when taken in excessive quantities or when combined with alcohol, acetaminophen may cause death due to liver failure. In fact, an overdose of acetaminophen is one of the most common causes of liver failure, as well as the most common cause of drug-induced liver disease in the United States. And, after acetaminophen became readily available in 1960 as an over-the- counter medication, it became one of the most popular instrumentality's for attempting suicide. For liver injury to occur, acetaminophen must generally be consumed in a quantity exceeding fifteen grams within a short period of time, such as in a single dose. Although uncommon, an ingestion of between seven to ten grams at one time may also cause liver damage. The consumption of alcohol in conjunction with acetaminophen significantly increases the likelihood that an individual will incur severe liver damage. Therefore, individuals who consume alcohol on a regular basis should probably limit acetaminophen intake to a maximum of one to two grams per day (i.e. two to four pills within a twenty-four hour period). Still, the best advise for individuals with liver disease is to totally abstain from alcohol. Individuals should take special note that acetaminophen is also an active ingredient in more than two hundred other medications, including Nyquil and Anacin 3. So, it is essential to carefully read the labels of all over-the- counter medications carefully. Other commonly used medications such as omeprazole (Prilosec), phenytoin ( Dilantin), and isoniazid (INH) may increase the risk of liver injury caused by acetaminophen. It is always in the liver patient's best interests to consult with his or her hepatologist prior to taking any medication. Acetylsalicylic acid (Aspirin) and other NSAIDs are drugs which are widely used for their anti-inflammatory and analgesic effects. They also have the potential to cause drug-induced liver disease. In fact, many NSAIDs have been withdrawn from the market due to their harmful effects on the liver (known as hepatotoxicity). All NSAIDs have the potential to cause liver injury. However, some NSAIDs are more hepatotoxic than others. The NSAIDs which are presently on the market, yet are frequently associated with liver injury are: aspirin (ASA), diclofenac (Voltaren), and sulindac (Clinoril). Therefore, individuals with liver disease should avoid using these NSAIDs. Older women seem to be particularly susceptible to the hepatotoxicity of NSAIDs, and are best advised to avoid NSAIDs altogether. Individuals who have developed complications of cirrhosis, (known as decompensated cirrhosis), such as ascites (accumulation of fluid in the abdomen) or bleeding esophageal varices (enlarged blood vessels in the esophagus), are at increased risk for kidney injury due to NSAIDs. Since this may lead to both liver and kidney failure, known as hepatorenal syndrome, individuals with advanced liver disease are best advised to totally avoid all NSAIDs. In conclusion, acetaminophen taken in moderate dosages is generally the safer choice for the relief of minor aches and pains occurring in individuals with any type of hepatitis or liver disease. __________________________________________________ Quote Link to comment Share on other sites More sharing options...
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