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Prednisone effects

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Hi ,

I'm curious about why the doctor wanted Diego to take his prednisone in two

separate doses, morning and afternoon? I've heard that the adrenal glands

normally release the body's naturally occurring corticosteroids in the a.m. and

that is why it is often suggested that one take prednisone in the morning.

Also, does an afternoon dose bother his sleep, keep him awake longer than

usual?

I'm sorry, I always seem to have more questions than answers! Still have lots

to learn! About the wounds taking longer to heal, I have read that that can be

a side effect of prednisone. We haven't noticed it with Josh. Even though he

takes so many medicines to try to weaken his overly active immune system. Josh

does seem to bruise more easily than he used to though, and the bruises do seem

to take longer to go away. A little bump on his shin normally leaves a bruise

for about a month. Not so, with my daughter.

People have had different responses to the other part of your question. In our

case, a viral infection seems to trigger more stills symptoms for Josh. A cold

usually takes much longer to go away and sometimes it triggers a flare up

again. I have heard of some parents home schooling their sick kids just so that

they don't keep catching colds and things from other kids in the classrooms.

Our rheumatologists have said that it's sometimes better to allow the child to

have exposure, so they can build up tolerance to these things. But when it

looks like Josh is getting sicker than normal, he usually boosts up the

prednisone dose if it may be heading toward a flare. Josh missed school

yesterday and the day before. The day before that, he actually put on his wrist

splints for the first time in a long while, because both wrists were hurting

and inflamed. It was rainy here and he woke up very sore and with a slight

fever, just over 101 degrees. He was more tired than usual, too. When I went in

to pick up his homework, the teacher told me that two kids had been sent home

sick, by the school nurse. So, who knows if maybe he caught something? He felt

better today, though, and went in. Not so sore. We had his blood and urine done

yesterday, so maybe there will be some slight elevations? We'll find out next

week Friday, when the doctors fly over and we have our appt.

Take Care,

Georgina

Siabala, wrote:

> From: " Siabala, " <MSiabala@...>

>

> Hi all,

> Dieguito is taking 5mg of Pred. in the morning and 5mg for the afternoon

> from last Wednesday and he haven't pains again.... But now he is caught a

> cold. He often clean his nose and now he have a little wounds around (three

> or four). He had a little scratch in his hand two weeks ago and this became

> a bladder that took one week in healing (type burn). He have now a mark in

> his hand. I think the same occurs in his nose and that it's and effect of

> Prednisone. The wouds not heal easily.... Also, I'm concerned about the

> cold. Could the pains return again for this?

> Have some of you had the same experience?

> Regards,

>

>

> ------------------------------------------------------------------------

>

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Hi Georgina,

Well, we simply obey the instructions of the doctor, how good kids! But I'll

ask he about this.... This morning Dieguito complained that it hurted him a

little the right thigh. I want wait to the night for observate him and call

to the doctor. Yesterday my sister in law forgot the tablet of the

morning... Do you believe that the reason of the pain is this? Or the flu?

He is better of his flu and the wouds are disappearing. Here we have many

heat because we are on summer and he sweats a lot, overall in the night.This

is the same from he have chicken pox.... I have to change his shirt two

times in the night...

Yesterday, I noticed that a little rash appear in his chin... I have a lot

of questions for the doctor....maybe this rash is for the heat, or Still, I

don't know....

Sorry for the flare of Josh, I hope he recovers very soon. Does he attend

regularly the school?

Give him a kiss on my behalf (of Diego too)

María

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Hi ,

My name is and it sounds like the predisone is affecting your sons

clotting cells which are called Thrombocytes also know as platelets.They give

blood the ability to clot. I am not a doctor it sounds like you should call

your doc on the matter if you didn't already do so. Sounds like your son is

having a hard time. Hope it calms down soon and everything is well.

Bye

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Hi ,

Thank you for your letter. At this moment Diego have a flare.... I supose

this is becuase he catch a cold a week ago... We called to the doctor and he

recommended increase to 15mg the dose of Pred. Also he is taking Mesulide,

other antiinflammatory one time in the day. He is better now but he have a

little pain in his back...

Regards,

--------------

[ ] Re: Prednisone effects

From: RPerre3314@...

Hi ,

My name is and it sounds like the predisone is affecting your sons

clotting cells which are called Thrombocytes also know as platelets.They

give

blood the ability to clot. I am not a doctor it sounds like you should call

your doc on the matter if you didn't already do so. Sounds like your son is

having a hard time. Hope it calms down soon and everything is well.

Bye

------------------------------------------------------------------------

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Hi ,

I'm not sure but if Diego didn't take his regular morning dose of prednisone,

that may be responsible for his increased pain. It really can have a fast

reaction like that. If Josh is even late with taking his, his body reacts in a

BIG way. It happened to us once, that Josh went to school without taking his

medicines. He got ill so quickly. Around 10 am I noticed that his medicines were

still in their little pill container on the kitchen counter. He usually takes

them at 7am. I called the school nurse and told her I would be driving in to

bring them for him and asked if she could go get him from his class. When I

arrived, he was in tears. He was so sore and had trouble walking to the health

room. He also had a high fever, so I wound up bringing him home that day.

When you take corticosteroids regularly, the body stops it's natural production.

There can be major consequences if you abruptly stop. One little girl on our

island had parents who got sick and tired of giving their little girl all the

medicines, day in and day out. They decided they would stop, without seeking

advice from the doctors. She had a major reaction to the lack of prednisone and

had to be airlifted off island to a major medical center in Oahu, to save her

life. It was very serious.

Like you said, Diego may be reacting to the flu. It sometimes does trigger worse

symptoms of the stills. It's hard to know sometimes why they feel well one day

and not the next. Is Diego running high fevers when he is sweating a lot? Josh

used to get fevers and chills. He would be shivering and feeling cold, while

still having high temps. He would soak through the sheets, too.

Josh was not having a flare yet, when I wrote before. I'm very sensitive to any

signs and maybe I was picking up some cues that suggested one might be coming.

Strangely enough, he has had high fevers for two days now. I still wouldn't call

it a flare, though. For us, the flares are much more serious. Or maybe I'm just

not ready for it to be so and am in a form of denial? I would really dislike

having to raise the prednisone back up again. So, I'm hoping that maybe he does

have some other type of infection going on, hopefully a viral type that will

need no more medicines and will just subside. Yesterday the difference between

his morning self and his afternoon self was so dramatic! It would really amaze

anyone who was not familiar with this. Gee ... it still amazes me!

Thank you for your positive thoughts.

Georgina

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  • 3 years later...

For those of you who are new, here are some odds and ends about Prednisone effects.

Weight gain is a concern most of us share. (I didn't know to expect it.). Weight isn't gained as it would be with simple overeating. There are specific patterns that usually occur. You probably know about the moon face; that will decrease as you take less prednisone. My face became so big (at 80 mg) I couldn't wear glasses in the usual way; I could hardly smile because my face was rigid with fat pads. Now, at 5 mg, I look normal, although not as I did before taking Prednisone.

Fat pads typically accumulate under the collar bones, at the wrists, and on the shoulder blade ("buffalo hump.") The waist line, not surprisingly, enlarges, from fat and muscle atrophy. Arms and legs typically become smaller, with Prednisone-related muscle atrophy. All these are the changes that would occur if your adrenal glands were hyper-active. Prednisone simulates that situation.

Other unpleasant cosmetic effects often take place. They are almost always temporary and include facial hair growth, odd body odor, reddened face, acne, hair loss.

We are likely to have mood swings, irritability, and alternating high energy and intense fatigue.

We need to guard against more important Prednisone effects: bone loss, glaucoma, cataracts, hypertension, diabetes. Talk to your doctor about these possibilities and make sure you are being monitored for them.

However, the important thing to remember is that Prednisone keeps us alive. In an earlier generation, before Prednisone, nothing could have been done to help us. Most of us who respond to standard therapy will have normal life spans!

Harper

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  • 4 months later...
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Hi...just a quick question for any of you who have been on prednisone for an extended time.....how long does it take before that nasty buffalo hump goes away from the back of your neck?

Debby

CA

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