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Re: drug induced AIH

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,

Yes, they are clearly 2 different things. Drug induced hepatitis is not the same as drug induced AIH. I'm sure Jerry has info on both somewhere in his big bag of tricks and will respond after reading your post. I too was under the impression some people here thought that after stopping the offending drug the AIH would go away. I wish it were that simple. Thanks for stating it so eloquently.

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Hi

your theory about the 'trigger effect' is basically the same as common

thought on the subject at the moment.

whatever the trigger aih progressing as it would..etc etc

though of course drug use does its own damage and so overall liver health is

worse.

unfortunately,with long term drug use taking the drug away does not mean the

damage will repair itself,sometimes the damage is just too great.

the liver pancreas and kidneys are all too often majorly damaged by certain

drugs,though usually the amounts for this to happen are excessive( drug

abuse)

blessings

amber

>From: " " <rthornton@...>

>Reply-

>

>Subject: [ ] " drug induced " AIH

>Date: Wed, 13 Nov 2002 20:28:13 -0000

>

>I am not sure about all the drug induced AIH, but these are my

>thoughts...for whatever it is worth.

>

>A person can have drug induced hepatitis. This IS NOT AIH and will

>resolve as soon as the offending drug is withdrawn, in time.

>

>The triggers for AIH are not well understood or known. There are

>some suspects (mostly what I have seen are viral theories), and I'm

>sure certain drugs may be on the list of suspects. If a drug does

>trigger AIH in a person, then the AIH will behave the same as if

>anything else triggered it. Once that switch is flipped it is a done

>deal...you have it. Removing the offending drug does not cause the

>hepatitis to resolve in this case because now the problem is the

>autoimmune reaction that has been triggered, not really the drug.

>

>So, to me there are two different possibilities:

>

>1. Drug induced hepatitis, remove the drug and the liver gets better.

>2. AIH that was triggered by a drug. This may be possible, but the

>AIH behaves the same no matter what the trigger...it does no resolve

>on its own and you have joined our AIH club!

>

>It could be that number 1. is misdiagnosed as number 2., I imagine.

>That may be the real question for some people.

>

>Any other thoughts?

>

>

>

Amber Leonard

_________________________________________________________________

The new MSN 8: smart spam protection and 2 months FREE*

http://join.msn.com/?page=features/junkmail

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Yes, I agree. I was under the impression that some people think that

if the AIH was triggered by a drug that once the drug was stopped so

would the AIH. I think this is possible in the case of drug induced

hepatitis, but NOT drug induced Autoimmune Hepatitis. Certainly long

term drug use takes its toll, but I would expect a purely drug

induced hepatitis would be caught before that. I guess it depends on

the frequency of blood tests, etc.

I didn't mean to imply the trigger theory was my own! I was just

making a distinction between hepatitis caused by a drug and

autoimmune hepatitis triggered by a drug...as I think they are really

two different things.

>

> Hi

> your theory about the 'trigger effect' is basically the same as

common

> thought on the subject at the moment.

> whatever the trigger aih progressing as it would..etc etc

> though of course drug use does its own damage and so overall liver

health is

> worse.

> unfortunately,with long term drug use taking the drug away does not

mean the

> damage will repair itself,sometimes the damage is just too great.

> the liver pancreas and kidneys are all too often majorly damaged

by certain

> drugs,though usually the amounts for this to happen are excessive(

drug

> abuse)

> blessings

> amber

>

> >From: " " <rthornton@u...>

> >Reply- @y...

> > @y...

> >Subject: [ ] " drug induced " AIH

> >Date: Wed, 13 Nov 2002 20:28:13 -0000

> >

> >I am not sure about all the drug induced AIH, but these are my

> >thoughts...for whatever it is worth.

> >

> >A person can have drug induced hepatitis. This IS NOT AIH and will

> >resolve as soon as the offending drug is withdrawn, in time.

> >

> >The triggers for AIH are not well understood or known. There are

> >some suspects (mostly what I have seen are viral theories), and I'm

> >sure certain drugs may be on the list of suspects. If a drug does

> >trigger AIH in a person, then the AIH will behave the same as if

> >anything else triggered it. Once that switch is flipped it is a

done

> >deal...you have it. Removing the offending drug does not cause the

> >hepatitis to resolve in this case because now the problem is the

> >autoimmune reaction that has been triggered, not really the drug.

> >

> >So, to me there are two different possibilities:

> >

> >1. Drug induced hepatitis, remove the drug and the liver gets

better.

> >2. AIH that was triggered by a drug. This may be possible, but the

> >AIH behaves the same no matter what the trigger...it does no

resolve

> >on its own and you have joined our AIH club!

> >

> >It could be that number 1. is misdiagnosed as number 2., I imagine.

> >That may be the real question for some people.

> >

> >Any other thoughts?

> >

> >

> >

>

>

> Amber Leonard

>

> _________________________________________________________________

> The new MSN 8: smart spam protection and 2 months FREE*

> http://join.msn.com/?page=features/junkmail

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...I'm sorry I posted on this before I read your post...... I

agree wholeheartedly with your evaluation as you can see by my

ramblings. Thanks for much better explanation..

love jerry

I am not sure about all the drug induced AIH, but these are my

thoughts...for whatever it is worth.

A person can have drug induced hepatitis. This IS NOT AIH and will

resolve as soon as the offending drug is withdrawn, in time.

The triggers for AIH are not well understood or known. There are

some suspects (mostly what I have seen are viral theories), and I'm

sure certain drugs may be on the list of suspects. If a drug does

trigger AIH in a person, then the AIH will behave the same as if

anything else triggered it. Once that switch is flipped it is a done

deal...you have it. Removing the offending drug does not cause the

hepatitis to resolve in this case because now the problem is the

autoimmune reaction that has been triggered, not really the drug.

So, to me there are two different possibilities:

1. Drug induced hepatitis, remove the drug and the liver gets better.

2. AIH that was triggered by a drug. This may be possible, but the

AIH behaves the same no matter what the trigger...it does no resolve

on its own and you have joined our AIH club!

It could be that number 1. is misdiagnosed as number 2., I imagine.

That may be the real question for some people.

Any other thoughts?

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  • 4 years later...

I just tell people hepatitis C and let them react as they will. HCV has a

stigma of being the IV drug user's disease and I've always felt that needs to be

changed. I don't care how they react. I understand the other side of the coin

though.

Best,

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Re the term hepatitis: when I found out I had AIH and told my sometime

boyfriend, his first questions were " Does this affect me? " " Is this something

I should be worried about? " Never asked anything about me. Needless to say,

he is no longer my boyfriend.

KayK TX, AIH/PBC

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I NEVER tell anyone that I have AIH. The general public is not receptive to

the word Hepatitis, because they don't know that it simply means 'inflamed

liver', right away they assume that you are contagious, or even a drug user.

Most of the time I just say that I have 4 auto-immune diseases, two of which

affect the liver.

Patsy

El Mirage, AZ

DX 2005 Stage 1 PBC

AIH/SLE/RA/COPD

Just a woman of letters....

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That is the truth! I have learned to say I have a liver disease and if they ask

further, I will explain, but often they just don't " get " it.

Debby

[ ] Re: drug induced AIH

I NEVER tell anyone that I have AIH. The general public is not receptive to

the word Hepatitis, because they don't know that it simply means 'inflamed

liver', right away they assume that you are contagious, or even a drug user.

Most of the time I just say that I have 4 auto-immune diseases, two of which

affect the liver.

Patsy

El Mirage, AZ

DX 2005 Stage 1 PBC

AIH/SLE/RA/COPD

Just a woman of letters....

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