Guest guest Posted April 14, 2001 Report Share Posted April 14, 2001 I visited my Dr.recently, and found my bloodwork okay except thyroglobulin...It was 139 and should be 39. She is talking about doing another biopsy, but I am against that since the first one was such a bad experience. I am on 2.5 mg. of Tapazole per day. Does anyone know about thyroglobulin? Thanks, Lori B Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 14, 2001 Report Share Posted April 14, 2001 Hi Lori, thyroglobulin is a protein made exclusively in the thyroid. It serves as the precursor or source for thyroid hormone since it contains the iodotyrosines that form thyroid hormone. Most of the body's throglobulin is stored as a colloid substance within the thyroid follicular cells but small amounts of thyroglobulin are secreted into the blood circulation when thyroid hormone is produced. In many different thyroid conditions, thyroglobulin levels in the blood are increased. Thyroglobulin levels are elevated in Graves' disease, multinodular goiter, papillary and follicular thyroid carcinomas, thyroiditis, and TSH dependent hyperthyroidism. Thyroglobulin levels are decreased after thyroidectomy, in thyroid aplasia and when hyperthyroidism is caused by taking excess thyroid hormone. Usually this test isn't used to diagnose thyroid disease. It's most often used to monitor treatment after surgery for patients with papillary, follicular, and Hurthle cell carcinomas. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 16, 2001 Report Share Posted April 16, 2001 Why does he want to do a second biospsy that he couldn't find in the first? Re: thyroglobulin I visited my Dr.recently, and found my bloodwork okay except thyroglobulin...It was 139 and should be 39. She is talking about doing another biopsy, but I am against that since the first one was such a bad experience. I am on 2.5 mg. of Tapazole per day. Does anyone know about thyroglobulin? Thanks, Lori B Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 30, 2009 Report Share Posted May 30, 2009 If someone has " normal " readings of tsh, t3 and t4 but the thyroglobulin is way high ( 105. What could that mean? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 31, 2009 Report Share Posted May 31, 2009 These are some pretty generic terms...do you mean total T3 and total T4 or do you mean free T3 and free T4? Also, are you referring to Tg (thyroglobulin) or TgAb (thyroglobulin antibodies)? Also, we would need to know lab values with ranges. > > If someone has " normal " readings of tsh, t3 and t4 but the thyroglobulin is way high ( 105. What could that mean? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted May 31, 2009 Report Share Posted May 31, 2009 loralsl wrote: > > > > If someone has " normal " readings of tsh, t3 and t4 but the thyroglobulin > is way high ( 105. What could that mean? Too much thyroglobulin means a binding issue. However, are you sure you don't mean thyroglobulin antibodies, which means something very different? Chuck Quote Link to comment Share on other sites More sharing options...
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