Re: Use of Ibuprofen with Hypo-T

[Guest guest]

If I've understood Chuck he says you're not supposed to take iodine with

your hyperthyroid medicine because it interferes with or maybe cancels

out the effects of the medication. But if you were taking TOO MUCH of

the hormone the iodine might help by counteracting some of the excess

and putting you closer to the recommended range. If that's the case you

should be able to get the same result by taking less Armour and no iodine.

But basically, I just don't know; I'm guessing.

>

> Re: Use of Ibuprofen with Hypo-T

>

<hypothyroidism/message/29499;_ylc=X3oDMTJxcWhjcDl\

zBF9TAzk3MzU5NzE1BGdycElkAzE0NTY2NARncnBzcElkAzE3MDkyNTEwODIEbXNnSWQDMjk0OTkEc2V\

jA2Rtc2cEc2xrA3Ztc2cEc3RpbWUDMTE4MzkzMTU0Ng-->

>

>

>

> Posted by: " Roni Molin " matchermaam@...

>

<mailto:matchermaam@...?Subject=%20Re%3A%20Use%20of%20Ibuprofen%20with%20H\

ypo-T>

> matchermaam <matchermaam>

>

>

> Sun Jul 8, 2007 1:16 pm (PST)

>

> What I don't understand, is that the package

> directions for Armour clearly say NOT to take Iodine.

> When I was first diognosed years ago, I also was told

> not to take iodine, and not even eat too much

> shellfish. How can someone take so much Armour and so

> much iodine and be o.k. Also, sex hormones sku the

> thyroid results.

>

> Roni

>

> --- Chuck B <gumboyaya@... <mailto:gumboyaya%40cox.net>> wrote:

>

> > Sam,

> >

> > You wrote:

> > >

> > > Since 1987, after breaking my back in an

> > equestrian accident, I have

> > > been taking 800mg Ibuprofen 3 times a day. That's

> > 20 years on 2400mg

> > > Ibuprofen per day (I have a hypErMobile rotating

> > sacrum).

> > >

> > > I always take with food, and have never had any

> > stomach issues or odd

> > > kidney/liver issues with it.

> >

> > The biggest concern was the combination with alcohol

> > as described in the

> > 1998 FDA warning:

> > http://www.fda.gov/bbs/topics/NEWS/NEW00659.html

> <http://www.fda.gov/bbs/topics/NEWS/NEW00659.html>

> >

> > By the time you have symptoms of liver damage, it is

> > too late. Perhaps

> > all that iodine is making you feel invincible.

> >

> > Chuck

[Guest guest]

Yes Vodka and Coke. It's actually quite good. I actually prefer dark

rum and coke with a little squeeze of lime, but the smell of rum

lingers on my breath long after the effects wear off.

I also like Midori (melon liquer) and orange juice...it's delicious,

but looks a bit like anti-freeze. Totally awesome over shaved ice.

Sam :-D

>

> i am sorry, did you say.........VODKA AND COKE? why coke? sounds

disgusting~ lol

[Guest guest]

hmmmm

well he who pays the piper calls the tune eh?

couldn't we have a health care system that supports wellness and evidence

based medicine, ie what works?

Gracia

Wouldn't these be the same dr's who would work in universal care? The

" Gatekeepers " to the good health the govt. wants us to all have?

Neil

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[Guest guest]

, you said:

" But basically, I just don't know, I'm guessing. "

You make me smile , lol.

If I've understood Chuck he says you're not supposed to take iodine with

your hyperthyroid medicine because it interferes with or maybe cancels

out the effects of the medication. But if you were taking TOO MUCH of

the hormone the iodine might help by counteracting some of the excess

and putting you closer to the recommended range. If that's the case you

should be able to get the same result by taking less Armour and no iodine.

But basically, I just don't know; I'm guessing.

************************************** See what's free at http://www.aol.com.

[Guest guest]

Aspirin has a profound affect on thyroid hormone creation. I t used to say on

every bottle to discuss with your doctor if you had thyroid problems. I don't

remember the exact wording but it was removed more than 20 years ago.

Here's some technical infor:

Salicylates.Acetylsalycilic acid has been identified as the most commonly

administered

medication which may cause significant alterations in measured parameters

of thyroid function.224b,224c Salicylate and its noncalorigenic congeners

(Fig. 5-3) compete

for thyroid hormone-binding sites on serum TTR and TBG.225-228 As a result,

the

serum concentrations of T4 and T3 decline and their free fractions

increase.228 The

turnover rate of T4 is accelerated, but degradation rates remain

normal.225,226 Salicylate

and its noncalorigenic congeners also suppress the thyroidal RAIU but do not

retard iodine release from the thyroid gland.312 The impaired respone to

TRH313 and

the hypermetabolic effect314 of salicylates have been attributed to the

increase in the

FT4 and FT3 fractions. If this were correct, hormonal release from the

serum-binding

proteins should produce only a temporary suppression of the thyroidal RAIU and

transient hypermetabolism, but both effects are observed during chronic

administration

of salicylates.225,226 In addition, this mechanism of action does not explain

the lack

of calorigenic effect of some salicylate congeners despite their ability to

also displace

thyroid hormone from its serum-binding proteins.

In vitro studies have demonstrated an inhibitory effect of salicylate on the

outer

ring monodeiodination of both T4 and rT3,315 but lack of typical changes in

serum

iodothyronine levels suggests that this action is less important in vivo.

Acetylsalicylic acid mimics some actions of thyroid hormone, but does not

reverse

classic manifestations of hypothyroidism. While salicylate administration may

lower

serum cholesterol levels,316 it does not provide a therapeutic effect in

myxedema, or

24

Chapter 5a. Effects of the Environment, Chemicals and Drugs on Thyroid

Function

lower TSH levels.317 Administration of 8 g aspirin daily raises the BMR to

normal in

myxedema, accelerates the circulation, and increases sweating, but it has no

effect on

the skin change, the electrocardiogram, or the mental state.316

Because of some analogies between the effects of salicylates and nitrophenol,

uncoupling

of oxidative phosphorylation has been suggested as one of its possible

mechanisms

of action. If this were the case, direct chemical action does not appear to be

involved since analogs of salicylate that do not uncouple oxidative

phosphorylation

in vitro are active in vivo.318

p-Aminosalicylic acid and p-aminobenzoic acid are closely related chemically

to salicylate.

They inhibit iodide binding in the thyroid gland and are goitrogenic.319,320

These agents also displace thyroid hormone from its serum protein-binding

sites.321

Abnormalities of thyroid function tests have been also reported in patients

treated

with salsalate.322

[Guest guest]

So true Dusty ... I always just delete the e-mails that I would have to study

for a day to even begin to understand.

In a message dated 7/9/2007 11:32:05 AM Eastern Daylight Time,

dusty@... writes:

WHAT does this mean? All this technical stuff and I still don't know what

you are tryng to convey to us. What do YOU mean when you say aspirin has

an effect on the " creation " of thyroid hormones?

Re: Use of Ibuprofen with Hypo-T

Aspirin has a profound affect on thyroid hormone creation. I t used to say

on every bottle to discuss with your doctor if you had thyroid problems. I

don't remember the exact wording but it was removed more than 20 years ago.

Here's some technical infor:

Salicylates.Salicylates.<WBR>Acetylsalycilic acid has been identified as

administered

medication which may cause significant alterations in measured parameters

of thyroid function.224b,of thyroid function.224b,<WBR>224c Salicylate an

(Fig. 5-3) compete

for thyroid hormone-binding sites on serum TTR and TBG.225-228 As a result,

the

serum concentrations of T4 and T3 decline and their free fractions

increase.228 The

turnover rate of T4 is accelerated, but degradation rates remain

normal.225,226 Salicylate

and its noncalorigenic congeners also suppress the thyroidal RAIU but do not

retard iodine release from the thyroid gland.312 The impaired respone to

TRH313 and

the hypermetabolic effect314 of salicylates have been attributed to the

increase in the

FT4 and FT3 fractions. If this were correct, hormonal release from the

serum-binding

proteins should produce only a temporary suppression of the thyroidal RAIU

and

transient hypermetabolism, but both effects are observed during chronic

administration

of salicylates.of salicylates.<WBR>225,226 In addition, this mechanis

explain the lack

of calorigenic effect of some salicylate congeners despite their ability to

also displace

thyroid hormone from its serum-binding proteins.

In vitro studies have demonstrated an inhibitory effect of salicylate on the

outer

ring monodeiodination of both T4 and rT3,315 but lack of typical changes in

serum

iodothyronine levels suggests that this action is less important in vivo.

Acetylsalicylic acid mimics some actions of thyroid hormone, but does not

reverse

classic manifestations of hypothyroidism. While salicylate administration

may lower

serum cholesterol levels,316 it does not provide a therapeutic effect in

myxedema, or

24

Chapter 5a. Effects of the Environment, Chemicals and Drugs on Thyroid

Function

lower TSH levels.317 Administration of 8 g aspirin daily raises the BMR to

normal in

myxedema, accelerates the circulation, and increases sweating, but it has no

effect on

the skin change, the electrocardiogram, or the mental state.316

Because of some analogies between the effects of salicylates and

nitrophenol, uncoupling

of oxidative phosphorylation has been suggested as one of its possible

mechanisms

of action. If this were the case, direct chemical action does not appear to

be

involved since analogs of salicylate that do not uncouple oxidative

phosphorylation

in vitro are active in vivo.318

p-Aminosalicylic acid and p-aminobenzoic acid are closely related chemically

to salicylate.

They inhibit iodide binding in the thyroid gland and are goitrogenic.They in

These agents also displace thyroid hormone from its serum protein-binding

sites.321

Abnormalities of thyroid function tests have been also reported in patients

treated

with salsalate.322

************************************** See what's free at http://www.aol.com.

[Guest guest]

WHAT does this mean? All this technical stuff and I still don't know what

you are tryng to convey to us. What do YOU mean when you say aspirin has

an effect on the " creation " of thyroid hormones?

Re: Use of Ibuprofen with Hypo-T

Aspirin has a profound affect on thyroid hormone creation. I t used to say

on every bottle to discuss with your doctor if you had thyroid problems. I

don't remember the exact wording but it was removed more than 20 years ago.

Here's some technical infor:

Salicylates.Acetylsalycilic acid has been identified as the most commonly

administered

medication which may cause significant alterations in measured parameters

of thyroid function.224b,224c Salicylate and its noncalorigenic congeners

(Fig. 5-3) compete

for thyroid hormone-binding sites on serum TTR and TBG.225-228 As a result,

the

serum concentrations of T4 and T3 decline and their free fractions

increase.228 The

turnover rate of T4 is accelerated, but degradation rates remain

normal.225,226 Salicylate

and its noncalorigenic congeners also suppress the thyroidal RAIU but do not

retard iodine release from the thyroid gland.312 The impaired respone to

TRH313 and

the hypermetabolic effect314 of salicylates have been attributed to the

increase in the

FT4 and FT3 fractions. If this were correct, hormonal release from the

serum-binding

proteins should produce only a temporary suppression of the thyroidal RAIU

and

transient hypermetabolism, but both effects are observed during chronic

administration

of salicylates.225,226 In addition, this mechanism of action does not

explain the lack

of calorigenic effect of some salicylate congeners despite their ability to

also displace

thyroid hormone from its serum-binding proteins.

In vitro studies have demonstrated an inhibitory effect of salicylate on the

outer

ring monodeiodination of both T4 and rT3,315 but lack of typical changes in

serum

iodothyronine levels suggests that this action is less important in vivo.

Acetylsalicylic acid mimics some actions of thyroid hormone, but does not

reverse

classic manifestations of hypothyroidism. While salicylate administration

may lower

serum cholesterol levels,316 it does not provide a therapeutic effect in

myxedema, or

24

Chapter 5a. Effects of the Environment, Chemicals and Drugs on Thyroid

Function

lower TSH levels.317 Administration of 8 g aspirin daily raises the BMR to

normal in

myxedema, accelerates the circulation, and increases sweating, but it has no

effect on

the skin change, the electrocardiogram, or the mental state.316

Because of some analogies between the effects of salicylates and

nitrophenol, uncoupling

of oxidative phosphorylation has been suggested as one of its possible

mechanisms

of action. If this were the case, direct chemical action does not appear to

be

involved since analogs of salicylate that do not uncouple oxidative

phosphorylation

in vitro are active in vivo.318

p-Aminosalicylic acid and p-aminobenzoic acid are closely related chemically

to salicylate.

They inhibit iodide binding in the thyroid gland and are goitrogenic.319,320

These agents also displace thyroid hormone from its serum protein-binding

sites.321

Abnormalities of thyroid function tests have been also reported in patients

treated

with salsalate.322

[Guest guest]

hmmmm - probably won't work Gracia..... consider the other drug kind of drug

users - you know, the addicted ones. They increase, increase, increase -

in search of a better high, complete euphoria- more,more, more. The usual

end result - death from overdose or burnt out , organ damaged, ravaged human

beings. Nobody can tell them they are over using either, because the

'evidence' for them is more doses - the better they feel.

Re: Re: Use of Ibuprofen with Hypo-T

hmmmm

well he who pays the piper calls the tune eh?

couldn't we have a health care system that supports wellness and evidence

based medicine, ie what works?

Gracia

Wouldn't these be the same dr's who would work in universal care? The

" Gatekeepers " to the good health the govt. wants us to all have?

Neil

_____

Recent Activity

a.. 8New Members

Visit Your Group

[Guest guest]

> >

> > Hi Bev,

> >

> > I get palpations in my thyroid gland. And a lump. Yup, goiter. The

> doc

> > just said " take Ibprofen. " Great (not great ha). I was desperate at

> > first (could'nt lay my head down on my pillow or it wout throb and

> I'd

> > also feel like I was choking), so I took the darn Ibprofen. But

> after

> > a few months I said the heck with that and did other,more natural

> > things. I had an additional problem tho. At that time the place I

> was

> > living was mold infested! And we couldn't afford to move at the

> time.

> > But now I am out of there and in my house. Phew.

> >

> > Reiki is the popular name for what has been used in many cultures.

> You

> > may be more familiar with it via Christian laying on of hands.

> Anyone

> > cna learn it, and its been discovered in nearly every culture, from

> > Hawaii (they call the energy mana) to India (prana) to China (chi

> or

> > ki... thus the name Rei-ki. Native Americans too. Uh oh, I can

> > really get into this, so time for me to go. ha

> >

> > ~ Priitaa

> >

> >

>

[Guest guest]

Ok, I was curious, so I googled it, and found some info from

Shomon's site:

From: http://thyroid.about.com/b/a/057857.htm

Can Ibuprofen and Aspirin Affect Your Thyroid?

" When we have an ache or pain, many of us reach for a nonsteroidal

anti-inflammatory drug (NSAID) like aspirin, or ibuprofen (Motrin,

Advil). But is this safe for your thyroid? A study was carried out to

determine the effects of nonsteroidal anti-inflammatory drugs

(NSAIDs) on thyroid tests. The NSAIDs tested were aspirin, salsalate,

meclofenamate, ibuprofen, naproxen, and indomethacin. Twenty-five

healthy subjects underwent a single-dose study and/or a one week

study. Total and free thyroid hormones and TSH were analyzed over an

eight hour period after a single dose and daily in the one week

study.

" Administration of ibuprofen (i.e., Advil, Motrin), naproxen, or

indomethacin of either a single dose or for one week did not change

the levels of any of the hormones measured. Various total and free

thyroid hormone measurements were decreased by single doses of

aspirin and salsalate and increased by meclofenamate.

" Treatment for one week with aspirin or salsalate decreased total T4,

free T4 (salsalate only), total T3, free T3, and TSH. Thus, this

study confirms that aspirin, salsalate, and meclofenamate affect

total and free thyroid hormone measurements.

" It also demonstrated that three NSAIDs (ibuprofen, naproxen, and

indomethacin) do not alter thyroid tests. During the acute (one dose)

and on week administration of these NSAIDs TSH levels remained with

the normal range. "

Source: http://jcem.endojournals.org/cgi/content/abstract/88/12/5710

>

> WHAT does this mean? All this technical stuff and I still don't

know what

> you are tryng to convey to us. What do YOU mean when you say

aspirin has

> an effect on the " creation " of thyroid hormones?

[Guest guest]

Heartfelt,

I agree with you that pain is your body trying to tell

you something. I try not to use painkillers for all

the reasons not to. What I get upset about is that the

doctors don't seems to be fazed at all when someone

comes in with pain. Live with it is one of the all

time arrogant statements I've heard, among others. My

MRI clearly shows there are many spinal issues, and

the reason I'm going to try this new physical

therapist is that she actually took the time to look

at the mri report.

Roni

--- HeartfeltTherapy@... wrote:

> Dear Bev you wrote: Why would you think that asprin

> is not good for hypoT

> people? I use Ibuprofen. I use up to 12 to 16 tabs.

> a day and I do good.

>

> Dear Bev,

>

> Your statement took my breath away! About 15 years

> ago, I took a lot of

> Ibuprofen everyday due to corporal tunnel that was

> so bad, my wrists, elbows and

> shoulders were screaming without it. I ended up in

> the hospital one day with

> even worse pain in my right arm and chest (the

> doctors thought I was having a

> heart attack). After x-rays, tons of testing etc...

> I was told my white blood

> count was off the charts. They finally figured out

> that I had an allergic

> reaction to the Ibuprofen.

>

> After that I wasn't able to take any pain medication

> for quite some time and

> the doctors have told me to be very careful and to

> only take Tylenol. Tylenol

> doesn't do anything for the inflammation which is at

> the base of corporal

> tunnel pain.

>

> From that point on, I had to learn to manage my pain

> without drugs and I've

> trained in over a dozen types of bodywork. (I'm too

> cheap to pay all that money

> for bodywork, without having something else to take

> away with it.) Initially

> I started studying as a way to get in-depth and

> intense bodywork done (one

> hour just didn't cut it) and to meet other

> bodyworkers in order to trade to

> manage my pain. I went from purely selfish reasons

> to a paradigm shift realizing

> the knowledge and experience I had, must be shared

> with others, because I found

> a cure to my corporal tunnel. I've also experienced

> other cures (although I'm

> currently questioning if the cures will be life long

> or not) for

> hypothyroidism (I joined this group because recently

> my periods have gone from 27 day cycle

> to 41 day cycle and I've started to gain weight

> without any change in eating

> or physical activity.) and no lateral support in my

> left knee (cured for 9

> years, but in the last 4 years has gone out

> momentarily and then right in again).

>

> My point, is to be very careful, as pain is a

> message from your body which

> needs attention, if ignored or medicated away will

> only be temporary and can

> compound issues which surely will bring you to a

> transition point beyond your

> immediate control. Transitions aren't generally fun

> for anyone, and neither is

> being in a position of not being in control of your

> life. Please listen to your

> pain and take care of yourself!

>

>

>

>

>

> ************************************** See what's

> free at http://www.aol.com.

>

>

> [Non-text portions of this message have been

> removed]

>

>

>

>

[Guest guest]

Sam, you are lucky, you can at least tolerate alcohol. Since becoming hypo, two

white wine spritzers (more spritz than wine I might add) has me asleep in a

chair like an old age pensioner, at any social gathering! But funnily enough if

I drink beer, (well, specifically Guinness) I am fine, weird isn't it?

Love, Val

Re: Re: Use of Ibuprofen with Hypo-T

i am sorry, did you say.........VODKA AND COKE? why coke? sounds disgusting~

lol

Sam <k9gang@...> wrote: <giggle> All those balanced hormones,

Iodoral, exercise, good

attitude, and good lovin' are making me feel invincible. I plan to

live to at least 150, and so far, so good.

I drink 2-3 vodka and cokes on a Friday and again on a Saturday.

That's it. Beer tastes icky to me, but I do make beer bread with it

(with unbrominated flour).

Yes, of course I am concerned about issues taking so much Ibuprofen

for such a long time. I test quite often because of that concern.

Over the course of the last 20 years, I have tried a wide variety of

pain relievers and ibuprofen is the best one which still allows me to

lead a normal life, but which only takes the " edge " off the pain. I

know if I was completely pain free I would do something stupid and

cripple myself even worse for life. This is what works " for me " . I

also use a small portable TENS unit a few times a week if necessary.

My sacrum was displaced in the accident and is NOT attached to the

ilium thingy on either side - it's real creepy to think about. I have

learned how to " reset " my sacrum, and do so a few times daily. It's

interesting to note that while still hypO, I had to reset my sacrum

every hour. Check this out...I was told by a orthopod specialist that

the surgery (bolting sacrum to ilium) to fix my rotating sacrum would

either make the pain worse, or paralyze me...HAH...no way jose'...

And now I must go out and pour/work 420 pounds of cement...where's my

trowel...

Sam

[snip]

>

> The biggest concern was the combination with alcohol as described

in the

> 1998 FDA warning:

> http://www.fda.gov/bbs/topics/NEWS/NEW00659.html

>

> By the time you have symptoms of liver damage, it is too late.

Perhaps

> all that iodine is making you feel invincible.

>

> Chuck

>

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