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Re: dysbiosis, indican, inulin....

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Hi ;

My inulin is inexpensive AND I get credit for it ;)

Here's the link to the inulin and the science:

http://members.shaw.ca/duncancrow/inulin_prebiotic_probiotic.html

Lung mucus, restricted airway and bathing difficulaty points to toxin

load all right, and paticulaly glutathione depletion. You can find

the science for glutathione in asthma and lung on the list on this

page:

http://members.shaw.ca/duncancrow/glutathione-refernces.html

Like said, vitamin b6, selenium and cold-procesed whey.

I've reduced COPD with a program that included that plus vitamin C

and vitamin E (the b6 was in b-complex)

Duncan

Duncan

>

> Hi all:

>

> I'm still trying to figure out what is causing my chronic lung

> mucus/throat-clearing. I've considered everything from candida to

LPR

> (silent reflux) to allergies to intestinal dysbiosis.. or some

> mixture of the above. I'd like to know if there would be some way

of

> diagnosing dysbiosis without getting an indican test? I'd be

> interested to hear how much it costs, if anyone has had it, just

for

> interest's sake. I'd rather save the money and spend it on inulin

and

> probiotics, since I'm assuming that's the " fix " anyway...

>

> I would think, for example, that if you have bad dysbiosis, you'd

> have maybe a rash (I never get rashes) or bad (poorly-formed) b-

m'rs

> (mine are pretty good since I've been chelating and taking Cortef)?

>

> I'd appreciate any comments or help in sorting this out, as it's

> really beginning to drive me NuTz! Maybe I should " spring " for some

> allergy tests ($400-600)? Can someone recommend a good source/brand

> of inulin (as it's one of the FEW things I have NOT tried over the

> past 15-20 years...

>

> Thank-you in advance,

> -michael

>

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Hi Duncan,

My daughter (3 1/2) has a chronic wet cough, with an occasional spiking of

symptoms with an acute asthma attack that lasts for about 48 hours. She is

anaphalactically allergic to casein, even in trace amounts. How would you

recommend that I increase her levels of glutathione?

Thanks!

Marla

Lung mucus, restricted airway and bathing difficulaty points to toxin

load all right, and paticulaly glutathione depletion. You can find

the science for glutathione in asthma and lung on the list on this

page:

http://members.shaw.ca/duncancrow/glutathione-refernces.html

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In a message dated 10/10/2006 12:28:49 PM Central Daylight Time,

yoonit@... writes:

.. I'd like to know if there would be some way of

diagnosing dysbiosis without getting an indican test? I'd be

What is and indican test?

How is it done?

<>kathy<>

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Cystine or N-acetylcysteine will also increase glutathione levels,

but NAC at least must be taken every four or five hours due to its

very short half life in the body. A little kid might do with 50-100

mg every four hours.

As usual the selenium is necessary too, in the baby's case about 50

mcg daily (and a b-complex) would be ballpark, depending on whether

and how much selenium is present in your drinking water in amounts

that will also offset the arsenic in the drinking water. Arsenic is

known to be a huge problem.

Another area of prime concern pertains to bad information on the

list with regard to selenium dosage. Although Bee

maintains that there is adequate selenium in Celtic sea salt to meet

one's needs, the manufacturer of Celtic sea salt says on their own

website that the selenium traces are so low the lab could not even

measure them.

An antioxidant pogram should also contain at least vitamin C, E, and

as points out, possibly A (or at least beta-carotenes), plus

vitamin D3 to make up for the " not milk " rule.

Duncan

>

> Hi Duncan,

>

> My daughter (3 1/2) has a chronic wet cough, with an occasional

spiking of

> symptoms with an acute asthma attack that lasts for about 48

hours. She is

> anaphalactically allergic to casein, even in trace amounts. How

would you

> recommend that I increase her levels of glutathione?

>

> Thanks!

> Marla

>

>

>

>

> Lung mucus, restricted airway and bathing difficulaty points to

toxin

> load all right, and paticulaly glutathione depletion. You can find

> the science for glutathione in asthma and lung on the list on this

> page:

>

> http://members.shaw.ca/duncancrow/glutathione-refernces.html

>

>

>

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Marla,

> My daughter (3 1/2) has a chronic wet cough, with an occasional spiking of

> symptoms with an acute asthma attack that lasts for about 48 hours. She is

> anaphalactically allergic to casein, even in trace amounts. How would you

> recommend that I increase her levels of glutathione?

Not only does pre-formed vitamin A (retinol from animal foods,

especially liver and cod liver oil) exert a glutathione-sparing

effect, but vitamin A is also important to asthma: asthmatic children

have low blood levels of vitamin A in proportion to the severity of

their asthma, vitamin A deficiency in animals causes a deficiency in

M2R muscarinic receptors which are required for bronchial relaxation,

vitamin A inhibits the migration and proliferation of smooth muscle

cells in the bronchial airway, and vitamin A can counter allergic

reactions by diverting bone marrow cells away from eosinophil

differentiation, which is a type of cell that is involved in the

allergic asthmatic response.

Vitamin K2, which is found in grass-fed animal fats and

lacto-fermented foods (and which is a different vitamin from vitamin

K1, which is found in green vegetables and does NOT fulfill the

functions of vitamin K2), was used in a highly successful

placebo-controlled double-blind study to treat asthma in the 1970s. I

don't know the mechanism, and there is no later research I've found

yet.

Chris

--

The Truth About Cholesterol

Find Out What Your Doctor Isn't Telling You:

http://www.cholesterol-and-health.com

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Duncan,

> An antioxidant pogram should also contain at least vitamin C, E, and

> as points out, possibly A (or at least beta-carotenes), plus

> vitamin D3 to make up for the " not milk " rule.

Supplementing with beta-carotene is the LAST thing you want to do

under conditions of oxidative stress, because carotenes are oxidized

to eccentric cleavage products that induce cellular VITAMIN A

DEFICIENCY.

Milk can't supply vitamin D3 beyond what prevents overt deficiency;

only seafood, pork or bovine blood (as in blood sausage), cod liver

oil and daily, summer full-body sunshine (possibly year-round sunshine

depending on latitude, but at most latitudes there is a portion of the

year where dietary vitamin D3 is essential) can supply sufficient

vitamin D3.

To get an idea, you can have your 25OHD levels checked (do NOT get the

1,25OH2D test!) and they should be about 40-60 ng/mL. To convert to

nmol/L multiply by 2.5

But " optimal " levels of vitamin D are dangerous unless the vitamin D3

is obtained with generous amounts of vitamins A and K2. The vitamin A

must be preformed vitamin A from animal foods. Vitamin K2 is found in

grass-fed animal fats and lactic acid fermented plant foods, although

the form in animal foods is more biologically active.

Chris

--

The Truth About Cholesterol

Find Out What Your Doctor Isn't Telling You:

http://www.cholesterol-and-health.com

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Well done, Chris; thank you for the information that beta-carotene is

contra-indicatd in oxidative stress.

Howeve, once the kid is on the NAC or cystine ad selenium for even a

few hours (NAC) to at most a couple of days (Cystine) there should be

no oxidative stress; NAC is used epecially for serious oxidative

stress especially in imminent or ongoing life-theatening liver

liquefaction precisely because it works in minutes to hours.

I agree that milk provides inadequate D3, but due to the " notmilk "

clause is this case that won't be a problem, as I suggested a

supplement.

I use milk ad lib myself, three cod-liver oil gelcaps and a 1,000 IU

D3 every day, even though I go outside four times a day, mainly

covered up. I live just south of the 49th parallel.

Also, I use amimal foods so I'm not concerned about my vitamin A

levels, I get betacarotenes from vegetables and because vitamin K2 is

also made by bacteria in the intestinal tract, like most of us

without dysbiosis I'm OK there too.

In this case with the kid all this information might be superfluous;

we haven't established anything beyond toxic/oxidative stress,

yielding asthma symptoms, exists at this point, although certainly we

can't rule out other issues at this point either.

As usual though your information is generally quite helpful.

Duncan

>

> Duncan,

>

> > An antioxidant pogram should also contain at least vitamin C, E,

and

> > as points out, possibly A (or at least beta-carotenes), plus

> > vitamin D3 to make up for the " not milk " rule.

>

> Supplementing with beta-carotene is the LAST thing you want to do

> under conditions of oxidative stress, because carotenes are oxidized

> to eccentric cleavage products that induce cellular VITAMIN A

> DEFICIENCY.

>

> Milk can't supply vitamin D3 beyond what prevents overt deficiency;

> only seafood, pork or bovine blood (as in blood sausage), cod liver

> oil and daily, summer full-body sunshine (possibly year-round

sunshine

> depending on latitude, but at most latitudes there is a portion of

the

> year where dietary vitamin D3 is essential) can supply sufficient

> vitamin D3.

>

> To get an idea, you can have your 25OHD levels checked (do NOT get

the

> 1,25OH2D test!) and they should be about 40-60 ng/mL. To convert to

> nmol/L multiply by 2.5

>

> But " optimal " levels of vitamin D are dangerous unless the vitamin

D3

> is obtained with generous amounts of vitamins A and K2. The

vitamin A

> must be preformed vitamin A from animal foods. Vitamin K2 is found

in

> grass-fed animal fats and lactic acid fermented plant foods,

although

> the form in animal foods is more biologically active.

>

> Chris

> --

> The Truth About Cholesterol

> Find Out What Your Doctor Isn't Telling You:

> http://www.cholesterol-and-health.com

>

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Duncan,

> Howeve, once the kid is on the NAC or cystine ad selenium for even a

> few hours (NAC) to at most a couple of days (Cystine) there should be

> no oxidative stress; NAC is used epecially for serious oxidative

> stress especially in imminent or ongoing life-theatening liver

> liquefaction precisely because it works in minutes to hours.

That's a good point, but we really have no idea to what extent

beta-carotene tends increase or decrease cellular vitamin A because

all that has ever been studied is blood levels, which are sort of

irrelevant to the cellular picture; we only know that oxidative stress

makes the situation worse. Ferrets given beta-carotene supplements

develop vitamin A deficiency-induced precancerous changes in their

lungs when they are not subjected to any type of abnormal oxidative

stress. We know that beta-carotene dissolved in an oil matrix can

remedy severe vitamin A deficiency, but there is no convincing

evidence that beta-carotene is a net positive vitamin A source rather

than a drain on cellular vitamin A levels in individuals who are not

severely vitamin A deficient.

Either way I think the various carotenes are beneficial, but one needs

to get true vitamin A as an insurance against the possibility that

those carotenes are in some capacity depleting vitamin A. I would

rely on the mixed carotenes in vegetables and grass-fed egg yolks and

milkfat personally, and I also use palm oil, which is an excellent

source of vitamin E (tocopherols and tocotrinols both) as well as

mixed carotenes..

> I agree that milk provides inadequate D3, but due to the " notmilk "

> clause is this case that won't be a problem, as I suggested a

> supplement.

Right -- I guess what I meant is that the supplement would have to

supply more than what would be in milk.

> I use milk ad lib myself, three cod-liver oil gelcaps and a 1,000 IU

> D3 every day, even though I go outside four times a day, mainly

> covered up. I live just south of the 49th parallel.

Going outside covered up will do practically nothing for vitamin D

levels, especially in Canada, so the cod liver oil, milk and D3

supplement must certainly be doing you a good bit of benefit.

Personally, I find I do best on 1-2 tablespoons of high-vitamin cod

liver oil. Each tablespoon supplies close to 4,000 IU of vitamin D,

and somwhere around 40,000 IU of vitamin A. I don't think most people

need this much in general, but for whatever reason I do.

> Also, I use amimal foods so I'm not concerned about my vitamin A

> levels, I get betacarotenes from vegetables and because vitamin K2 is

> also made by bacteria in the intestinal tract, like most of us

> without dysbiosis I'm OK there too.

According to the current vitamin K researchers, it is near universally

regarded as disproven that intestinal bacteria are a significant

source of vitamin K. I have not read the primary research myself, but

I have come across this opinion in the introductions and discussions

of all the vitamin K studies I have read and I have not seen contrary

opinions.

> In this case with the kid all this information might be superfluous;

> we haven't established anything beyond toxic/oxidative stress,

> yielding asthma symptoms, exists at this point, although certainly we

> can't rule out other issues at this point either.

Well, for oxidative stress, I think preformed vitamin A is an

important part of any program. But more importantly, vitamin A and

vitamin K2 are probably essential asthma treatments, for the reasons I

stated in my other email. Also, almost everyone is deficient in

vitamin D, and it should be routinely tested since we have a better

idea of what an optimal blood level is than we have for any of the

other vitamins, and since vitamin D-associated parameters appear to be

a direct function of 25OHD levels. Since deficiency is so common, and

since status is so easy to assess, it's a sensible for everyone to

address it for any problem, or even in the absence of an obvious

problem, in my opinion.

> As usual though your information is generally quite helpful.

Thanks. Yours too.

Chris

--

The Truth About Cholesterol

Find Out What Your Doctor Isn't Telling You:

http://www.cholesterol-and-health.com

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Hi Duncan:

The 1st link worked, but not the 2nd..

So you're sure this sounds like dysbiosis? I've never had asthma or

breathing difficulties, just lots of mucus which causes me to clear

my throat. SOme people say I might have silent reflux. There must be

some way to differentiate this stuff? Why would I have dysbiosis?

I've been a health nut for years. I eat more veggies than anyone I

know. Never any junk. The only theory in support of it might be that

I was a 100% bottle baby, which I've read can mean that my intestinal

tract may have never properly developed....

-michael

> >

> > Hi all:

> >

> > I'm still trying to figure out what is causing my chronic lung

> > mucus/throat-clearing. I've considered everything from candida to

> LPR

> > (silent reflux) to allergies to intestinal dysbiosis.. or some

> > mixture of the above. I'd like to know if there would be some way

> of

> > diagnosing dysbiosis without getting an indican test? I'd be

> > interested to hear how much it costs, if anyone has had it, just

> for

> > interest's sake. I'd rather save the money and spend it on inulin

> and

> > probiotics, since I'm assuming that's the " fix " anyway...

> >

> > I would think, for example, that if you have bad dysbiosis, you'd

> > have maybe a rash (I never get rashes) or bad (poorly-formed) b-

> m'rs

> > (mine are pretty good since I've been chelating and taking

Cortef)?

> >

> > I'd appreciate any comments or help in sorting this out, as it's

> > really beginning to drive me NuTz! Maybe I should " spring " for

some

> > allergy tests ($400-600)? Can someone recommend a good

source/brand

> > of inulin (as it's one of the FEW things I have NOT tried over

the

> > past 15-20 years...

> >

> > Thank-you in advance,

> > -michael

> >

>

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http://members.shaw.ca/duncancrow/glutathione-references.html

> The 1st link worked, but not the 2nd..

>

> So you're sure this sounds like dysbiosis? I've never had asthma or

> breathing difficulties, just lots of mucus which causes me to clear

> my throat. SOme people say I might have silent reflux. There must

be

> some way to differentiate this stuff? Why would I have dysbiosis?

You can guess dysbiosis by analysing prebiotic content of your diet.

Commercial veggies don't really provide all the inulin you need to

reverse dysbiosis but do provide enough to maintain health because a

healthy bowel ecology is resilient.

Dysbiosis is in many people a key source of toxin load, and

glutathione and antioxidant depletion. We know it aggravates

oxidative stress diseases, asthma iritation and mucus production

included. GERD is a product of hypochlordydria, which can result from

dysbiosis through malabsorption and subsequent malnutrition. It isn't

necessarily a connection but it does seem like a good bet, doesn't

it? And it's pretty cheap to find out.

Duncan

> I've been a health nut for years. I eat more veggies than anyone I

> know. Never any junk. The only theory in support of it might be

that

> I was a 100% bottle baby, which I've read can mean that my

intestinal

> tract may have never properly developed....

>

> -michael

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>

> http://members.shaw.ca/duncancrow/glutathione-references.html

>

> > The 1st link worked, but not the 2nd..

> >

> > So you're sure this sounds like dysbiosis? I've never had asthma

or

> > breathing difficulties, just lots of mucus which causes me to

clear

> > my throat. SOme people say I might have silent reflux. There must

> be

> > some way to differentiate this stuff? Why would I have dysbiosis?

>

> You can guess dysbiosis by analysing prebiotic content of your

diet.

> Commercial veggies don't really provide all the inulin you need to

> reverse dysbiosis but do provide enough to maintain health because

a

> healthy bowel ecology is resilient.

>

> Dysbiosis is in many people a key source of toxin load, and

> glutathione and antioxidant depletion. We know it aggravates

> oxidative stress diseases, asthma iritation and mucus production

> included. GERD is a product of hypochlordydria, which can result

from

> dysbiosis through malabsorption and subsequent malnutrition. It

isn't

> necessarily a connection but it does seem like a good bet, doesn't

> it? And it's pretty cheap to find out.

>

>

> Duncan

Yes...it's cheap to try. It will be quite an experience to taste

something as sweet as sugar after avoiding sweets for years. I also

wanted to try some good whey again. Can you recommend a source or

brand (I'll bet you can -ha). I'll also give NAC another try -this

time split doses. By the way (not that it matters) but I eat mostly

organic and homegrown veggies, not " commercial. " But as I seem to

have malabsorption, I'm probably still low in some nutrients..

Thanks alot Duncan..I'll let you know what happens

-michael

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Just thought of something --that being perhaps only marginal

dysbiosis combined with marginal antioxidant, epecially glutathione,

depletion. Arsenic in the drinking water, not enough selenium, and

the precusors for glutathione being inadequate to meet the task of

arsenic and toxin load, could still produce the lung effect even

though overall toxicity is fairly low.

Glutathione is supposed to be plentiful in the lungs, and as people

age they produce less of it anyway.

Glutathione precursors are in raw food, and certainly, babies' milk.

Most people eat nearly all of their veggies cooked so the glutathione

precursors are pooched.

So, maybe a meeting of two marginal conditions applies. Perhaps Chris

can suggest the appropriate tests.

Duncan

>

> http://members.shaw.ca/duncancrow/glutathione-references.html

>

> > The 1st link worked, but not the 2nd..

> >

> > So you're sure this sounds like dysbiosis? I've never had asthma

or

> > breathing difficulties, just lots of mucus which causes me to

clear

> > my throat. SOme people say I might have silent reflux. There must

> be

> > some way to differentiate this stuff? Why would I have dysbiosis?

>

> You can guess dysbiosis by analysing prebiotic content of your

diet.

> Commercial veggies don't really provide all the inulin you need to

> reverse dysbiosis but do provide enough to maintain health because

a

> healthy bowel ecology is resilient.

>

> Dysbiosis is in many people a key source of toxin load, and

> glutathione and antioxidant depletion. We know it aggravates

> oxidative stress diseases, asthma iritation and mucus production

> included. GERD is a product of hypochlordydria, which can result

from

> dysbiosis through malabsorption and subsequent malnutrition. It

isn't

> necessarily a connection but it does seem like a good bet, doesn't

> it? And it's pretty cheap to find out.

>

>

> Duncan

>

> > I've been a health nut for years. I eat more veggies than anyone

I

> > know. Never any junk. The only theory in support of it might be

> that

> > I was a 100% bottle baby, which I've read can mean that my

> intestinal

> > tract may have never properly developed....

> >

> > -michael

>

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