Guest guest Posted March 15, 2004 Report Share Posted March 15, 2004 Let's just correct this statement: > Alternatively, the majority of exogenous N-Acetyl-Cysteine > (NAC) is converted to Glutathione (the NAC form of Cysteine, unlike L- > Cysteine, is not oxidized Balderdash (an English term... ... NAC produces pretty strong toxic side effects at the doses required (400-500 mg every 4-5 hours) to max out glutathione production. This is because the cycteine is more absorbable in this form BUT it is still very unstable and it produces toxic metabolites, just like cysteine does. When the drug is withdrawn, glutathione levels plummet often to below original readings. All infections tend to reduce glutathione reserves. Low glutathione STIMULATES infection, so care must be taken to not miss doses of NAC. This is why the research states that the it isn't very useful; it produces almost as much toxin load as it corrects. The FDA website states that properly-made undenatured whey isolate is the best way to increase cellular glutathione. Moving along, I think also that note should be made that some substances that increase glutathione levels, are doing it not by stimulating production but by mounting a real or perceived challenge to glutathione levels, thus increasing those levels. This is not all good. Also, some things elevate glutathione by inhibiting depletion. This in fact is preventing glutathione from being used as an antioxidant or detoxifier. This is not all good either; it's supposed to be used. So we increase production, but use all we need to. regards, Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 15, 2004 Report Share Posted March 15, 2004 > Let's just correct this statement: > > > Alternatively, the majority of exogenous N-Acetyl-Cysteine > > (NAC) is converted to Glutathione (the NAC form of Cysteine, unlike L- > > Cysteine, is not oxidized > > Balderdash (an English term... ... > > NAC produces pretty strong toxic side effects at the doses required > (400-500 mg every 4-5 hours) to max out glutathione production. > > This is because the cycteine is more absorbable in this form BUT it > is still very unstable and it produces toxic metabolites, just like > cysteine does. > > When the drug is withdrawn, glutathione levels plummet often to below > original readings. All infections tend to reduce glutathione > reserves. Low glutathione STIMULATES infection, so care must be taken > to not miss doses of NAC. > > This is why the research states that the it isn't very useful; it > produces almost as much toxin load as it corrects. The FDA website > states that properly-made undenatured whey isolate is the best way to > increase cellular glutathione. You want us to go by what the Food and Drug Administration says? Aren't they controlled by the Drug industry? Rick Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 15, 2004 Report Share Posted March 15, 2004 > You want us to go by what the Food and Drug Administration says? > > Aren't they controlled by the Drug industry? > Yes they are controlled by Big Pharma, but not everything the FDA states is wrong; they have to maintain a facade of credibility, so they liberally mix the wheat back into the chaff, so to speak. If you want good information then you can always go to the source, the research. regards, Duncan Crow Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 15, 2004 Report Share Posted March 15, 2004 Rick, Touché! Let's just correct this statement: Alternatively, the majority of exogenous N-Acetyl-Cysteine (NAC) is converted to Glutathione (the NAC form of Cysteine, unlike L-> > Cysteine, is not oxidized Balderdash (an English term... ... NAC produces pretty strong toxic side effects at the doses required (400-500 mg every 4-5 hours) to max out glutathione production. This is because the cycteine is more absorbable in this form BUT it is still very unstable and it produces toxic metabolites, just like cysteine does. When the drug is withdrawn, glutathione levels plummet often to below original readings. All infections tend to reduce glutathione reserves. Low glutathione STIMULATES infection, so care must be taken to not miss doses of NAC. This is why the research states that the it isn't very useful; it produces almost as much toxin load as it corrects. The FDA website states that properly-made undenatured whey isolate is the best way to increase cellular glutathione. You want us to go by what the Food and Drug Administration says? Aren't they controlled by the Drug industry? Rick Quote Link to comment Share on other sites More sharing options...
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