Guest guest Posted February 19, 2004 Report Share Posted February 19, 2004 Postpartum pituitary necrosis Postpartum hemorrhage and hypovolemia can cause infarction of part or all of the pituitary gland, resulting in postpartum pituitary necrosis, or Sheehan's syndrome. Depending on the amount of pituitary tissue that has been destroyed, acute hypopituitarism can occur immediately, or deficiency can develop slowly over many years. The acute form is associated with persistent hypotension, tachycardia, failure to lactate, and hypoglycemia and requires prompt treatment with glucocorticoids. The slowly developing form often begins as postpartum amenorrhea and an inability to lactate; after many years, the classic features of hypothyroidism and adrenal insufficiency may manifest themselves (2). Quote Link to comment Share on other sites More sharing options...
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