Guest guest Posted May 20, 1999 Report Share Posted May 20, 1999 Just found this on Intellihealth and thought it was an exciting and promising possibility for all of us to follow: **************************************************************************** *** WESTPORT, May 14 (Reuters Health) - There is a cell associated with bone marrow that is capable of developing into a functioning hepatocyte, a group of US and Canadian scientists report in the May 14th issue of Science. " Bone marrow stem cells develop into hematopoietic and mesenchymal lineages but have not been known to participate in production of hepatocytes, biliary cells, or oval cells during liver regeneration, " Dr. Byron E. sen of the University of Pittsburgh in Pennsylvania and colleagues explain in the paper.They attempted to retrace the origin of repopulating hepatic cells. In an interview with Reuters Health, Dr. sen said that his group " ...did this experiment to see whether oval cells may actually be coming from the bone marrow instead of hepatic derived, as everybody has been thinking for the last 40 years. " Dr. sen's group took bone marrow from male rats and transplantedthe bone marrow into " lethally irradiated " female rats and followed the Y chromosome through a series of experiments to see where that marker would end up in the liver. They discovered that some of the regenerated hepatic cells were donor-derived. " The combined data suggest that at day 9, the oval cells...in the recipient female are derived from the donor male and that they continue to differentiate into mature hepatocytes by day 13, " the group reports in the Science paper. The clinical implications could be " quite substantial, " Dr. sen told Reuters Health. " We may actually be able to use a persons own bone marrow cells and get them to differentiate into hepatocytes and then transplant them back into their own liver without having to go through the trauma of a liver transplant.If this technology will lend itself to it, and we can do some gene therapy, we may actually be able to repair a defective liver. " Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 15, 2003 Report Share Posted July 15, 2003 Patty: That must have been disappointing news about the other lady with the B Blood. It seems like you have been "on the edge" for such a long time. Are you sure you are feeling up to working? What kind of work do you do? I agree, that you can only quarantine yourself for so long before you go nuts! Take care and take one day at a time. Love, Marty [ ] transplant news Finding out where everyone is from is great fun. I don't recall who started it but thank you. I hope it continues, Florida will come out victorious! Anyway, I found out this morning I am no longer 1st on the local list for a B liver. There is a woman who jumped ahead of me. I was told it doesn't affect me, that she needs a much larger liver but it does put forth the reality of the wait and lack of control we have over this transplant situation. Time on the list matters, I've said this before but I feel I need to repeat it. If you are referred to a transplant team, see then as soon as you can, and get on the list. Even if your Meld score is 7 or 8 you will be accumulating time. They wont transplant you before they need to, they can't even put you on the list unless you qualify but give it a shot. MELD score matters more but if there are two or more people with the same MELD score the person on the list longer gets the liver. I am going to try and go back to work a couple of hours a day, see what happens. I can only sit around and wait for so long. Patty -----Original Message-----From: tazz001@... [mailto:tazz001@...] Sent: Tuesday, July 15, 2003 4:06 AM Subject: [ ] Another Georgia Peach ! Hello ! I best get back in bed quickly to get more rest for morning but couldn't resist to send you another photo of a famous Georgia Peach; Our Annual Peach Drop for New Years at Underground Atlanta !!! Patty ! do you guys an orange drop for New Years Eve ! Love, Tony Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 15, 2003 Report Share Posted July 15, 2003 Marty, I am disappointed, although it's hard to feel badly about someone else being more sick than I am, that's what is so difficult about the transplant waiting list. There is something wrong with a system where people compete for a scarce resource that will keep some of them alive. I am on the edge, the thing about working is that I can feel useful and the day passes quickly, the bad thing is that I have been given permission to work 'a couple of hours', every other day. It takes me 45 minutes to drive to work and another 45 to get home so it's hardly worth it. I had a follow-up appt today with my oncologist, he suggested I just do what I can from home through email, phone & fax and not get stressed out by going in. He has a good point. For me working is not physically stressful but it can be mentally. I am a Professor of Occupational Therapy at Florida International University. This summer I am teaching a course on-line. It is very unstressful as it is in my area of research interest, the Americans with Disabilities Act and employment accommodation. I have someone to back me up if and when I go in for the transplant. I have all kinds of contingency plans. If I went in to the University there are any number of things people would drive me crazy about. I consider myself incredibly fortunate to have a career that I can continue even with all these health problems. Fortunately my husband works evenings so I don't drive him crazy. I do take each day at a time, what is the alternative? Thanks, Patty -----Original Message-----From: msaire [mailto:msaire@...] Sent: Tuesday, July 15, 2003 9:14 PM Subject: Re: [ ] transplant news Patty: That must have been disappointing news about the other lady with the B Blood. It seems like you have been "on the edge" for such a long time. Are you sure you are feeling up to working? What kind of work do you do? I agree, that you can only quarantine yourself for so long before you go nuts! Take care and take one day at a time. Love, Marty [ ] transplant news Finding out where everyone is from is great fun. I don't recall who started it but thank you. I hope it continues, Florida will come out victorious! Anyway, I found out this morning I am no longer 1st on the local list for a B liver. There is a woman who jumped ahead of me. I was told it doesn't affect me, that she needs a much larger liver but it does put forth the reality of the wait and lack of control we have over this transplant situation. Time on the list matters, I've said this before but I feel I need to repeat it. If you are referred to a transplant team, see then as soon as you can, and get on the list. Even if your Meld score is 7 or 8 you will be accumulating time. They wont transplant you before they need to, they can't even put you on the list unless you qualify but give it a shot. MELD score matters more but if there are two or more people with the same MELD score the person on the list longer gets the liver. I am going to try and go back to work a couple of hours a day, see what happens. I can only sit around and wait for so long. Patty -----Original Message-----From: tazz001@... [mailto:tazz001@...] Sent: Tuesday, July 15, 2003 4:06 AM Subject: [ ] Another Georgia Peach ! Hello ! I best get back in bed quickly to get more rest for morning but couldn't resist to send you another photo of a famous Georgia Peach; Our Annual Peach Drop for New Years at Underground Atlanta !!! Patty ! do you guys an orange drop for New Years Eve ! Love, Tony Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 15, 2003 Report Share Posted July 15, 2003 Patty: Some of my best friends are OT's - I think it is a wonderful profession and I have always enjoyed working together with OT's on treatment goals for the mentally ill. I suppose if I got creative I could find something to do at home as a nurse as well. Right now I have no interest in working, but the time may come again. Well I have another 1/2 hour in which I can eat or drink until tomorrow so I was thinking of a small dish of ice cream with strawberries. Then off to bed. Nice chatting with you and I will include you in my prayers, as usual. What hospital will you have your transplant at, and how will we know when you get your call? Marty -- RE: [ ] transplant news Marty, I am disappointed, although it's hard to feel badly about someone else being more sick than I am, that's what is so difficult about the transplant waiting list. There is something wrong with a system where people compete for a scarce resource that will keep some of them alive. I am on the edge, the thing about working is that I can feel useful and the day passes quickly, the bad thing is that I have been given permission to work 'a couple of hours', every other day. It takes me 45 minutes to drive to work and another 45 to get home so it's hardly worth it. I had a follow-up appt today with my oncologist, he suggested I just do what I can from home through email, phone & fax and not get stressed out by going in. He has a good point. For me working is not physically stressful but it can be mentally. I am a Professor of Occupational Therapy at Florida International University. This summer I am teaching a course on-line. It is very unstressful as it is in my area of research interest, the Americans with Disabilities Act and employment accommodation. I have someone to back me up if and when I go in for the transplant. I have all kinds of contingency plans. If I went in to the University there are any number of things people would drive me crazy about. I consider myself incredibly fortunate to have a career that I can continue even with all these health problems. Fortunately my husband works evenings so I don't drive him crazy. I do take each day at a time, what is the alternative? Thanks, Patty -----Original Message-----From: msaire [mailto:msaire@...] Sent: Tuesday, July 15, 2003 9:14 PM Subject: Re: [ ] transplant news Patty: That must have been disappointing news about the other lady with the B Blood. It seems like you have been "on the edge" for such a long time. Are you sure you are feeling up to working? What kind of work do you do? I agree, that you can only quarantine yourself for so long before you go nuts! Take care and take one day at a time. Love, Marty [ ] transplant news Finding out where everyone is from is great fun. I don't recall who started it but thank you. I hope it continues, Florida will come out victorious! Anyway, I found out this morning I am no longer 1st on the local list for a B liver. There is a woman who jumped ahead of me. I was told it doesn't affect me, that she needs a much larger liver but it does put forth the reality of the wait and lack of control we have over this transplant situation. Time on the list matters, I've said this before but I feel I need to repeat it. If you are referred to a transplant team, see then as soon as you can, and get on the list. Even if your Meld score is 7 or 8 you will be accumulating time. They wont transplant you before they need to, they can't even put you on the list unless you qualify but give it a shot. MELD score matters more but if there are two or more people with the same MELD score the person on the list longer gets the liver. I am going to try and go back to work a couple of hours a day, see what happens. I can only sit around and wait for so long. Patty -----Original Message-----From: tazz001@... [mailto:tazz001@...] Sent: Tuesday, July 15, 2003 4:06 AM Subject: [ ] Another Georgia Peach ! Hello ! I best get back in bed quickly to get more rest for morning but couldn't resist to send you another photo of a famous Georgia Peach; Our Annual Peach Drop for New Years at Underground Atlanta !!! Patty ! do you guys an orange drop for New Years Eve ! Love, Tony Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 15, 2003 Report Share Posted July 15, 2003 Marty, I consider myself lucky to have gone into OT, I love it. Nothing I would rather be doing. Before I started teaching I worked in psych. I still keep my hand in it when I am healthy. You will know. If I have a chance after they call I will post a note here. I have received so much support from this group, I know you are all wanting to hear the news. If I am not home when they call, or if for some reason I can't my husband has instructions to let you know. Last time I had the transplant he made a web page so everyone who wanted to know could log on and get a day by day, I think he will do the same this time. I will be at the University of Miami, Memorial Hospital, same place Genny & Jodi had their surgeries, also goes there. Why go for the small dish, have a big dish with lots of strawberries, I love the fruit this time of year. Good luck tomorrow. Patty RE: [ ] transplant news Marty, I am disappointed, although it's hard to feel badly about someone else being more sick than I am, that's what is so difficult about the transplant waiting list. There is something wrong with a system where people compete for a scarce resource that will keep some of them alive. I am on the edge, the thing about working is that I can feel useful and the day passes quickly, the bad thing is that I have been given permission to work 'a couple of hours', every other day. It takes me 45 minutes to drive to work and another 45 to get home so it's hardly worth it. I had a follow-up appt today with my oncologist, he suggested I just do what I can from home through email, phone & fax and not get stressed out by going in. He has a good point. For me working is not physically stressful but it can be mentally. I am a Professor of Occupational Therapy at Florida International University. This summer I am teaching a course on-line. It is very unstressful as it is in my area of research interest, the Americans with Disabilities Act and employment accommodation. I have someone to back me up if and when I go in for the transplant. I have all kinds of contingency plans. If I went in to the University there are any number of things people would drive me crazy about. I consider myself incredibly fortunate to have a career that I can continue even with all these health problems. Fortunately my husband works evenings so I don't drive him crazy. I do take each day at a time, what is the alternative? Thanks, Patty -----Original Message-----From: msaire [mailto:msaire@...] Sent: Tuesday, July 15, 2003 9:14 PM Subject: Re: [ ] transplant news Patty: That must have been disappointing news about the other lady with the B Blood. It seems like you have been "on the edge" for such a long time. Are you sure you are feeling up to working? What kind of work do you do? I agree, that you can only quarantine yourself for so long before you go nuts! Take care and take one day at a time. Love, Marty [ ] transplant news Finding out where everyone is from is great fun. I don't recall who started it but thank you. I hope it continues, Florida will come out victorious! Anyway, I found out this morning I am no longer 1st on the local list for a B liver. There is a woman who jumped ahead of me. I was told it doesn't affect me, that she needs a much larger liver but it does put forth the reality of the wait and lack of control we have over this transplant situation. Time on the list matters, I've said this before but I feel I need to repeat it. If you are referred to a transplant team, see then as soon as you can, and get on the list. Even if your Meld score is 7 or 8 you will be accumulating time. They wont transplant you before they need to, they can't even put you on the list unless you qualify but give it a shot. MELD score matters more but if there are two or more people with the same MELD score the person on the list longer gets the liver. I am going to try and go back to work a couple of hours a day, see what happens. I can only sit around and wait for so long. Patty -----Original Message-----From: tazz001@... [mailto:tazz001@...] Sent: Tuesday, July 15, 2003 4:06 AM Subject: [ ] Another Georgia Peach ! Hello ! I best get back in bed quickly to get more rest for morning but couldn't resist to send you another photo of a famous Georgia Peach; Our Annual Peach Drop for New Years at Underground Atlanta !!! Patty ! do you guys an orange drop for New Years Eve ! Love, Tony Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 15, 2003 Report Share Posted July 15, 2003 Marty....like Patty says.... have a big dish with lots of strawberries and maybe some chocolate syrup and a banana or two, don't waste an opportunity....good luck. my prayers and love jerry (whipped cream?) Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 16, 2003 Report Share Posted July 16, 2003 Actually, this is a small bathroom. American Standard makes a tub that fits in the space of a typical 5' tub. The difference is it is taller. I am really looking forward to it. Hey since we had to redo it ,,, major water damage (slow leak under the tile floor) we figured we would do it right! I'll post pics when it is done! Patty -----Original Message-----From: tdcc [mailto:tdcc2000@...] Sent: Wednesday, July 16, 2003 8:21 PM Subject: Re: [ ] Re: transplant news Oh wow Patty, that new bathroom is wonderful! My bathrooms are very small and I couldn't ever have a whirlpool tub...but boy...would I ever like one! Really happy it is turning out great! Debby RE: [ ] Re: transplant news Hi Amy, Since you had that bout with infections... the hard part is you work with kids. I can tell my students and colleagues to stay away from me if they have a cold but yours may not be careful to cover their mouth & nose when they cough & sneeze and wash their hands. Every semester I tell my students I am immunosuppressed and to sit in the back if they have a cold and let me know if they need to come to my office or whatever. There is always at least one student who will call & tell me 'Sorry I missed class today, I have a cold and didn't want to give it to you". Great excuse, it doesn't work though. They are not EXCUSED from class, I just want them to sit away from me! I need to do some OT for myself. I never thought it would be this long, If someone had told me 3 months I would have approached this much differently than thinking it was any day. I have been doing my exercises in the pool every day, I actually have quite a good tan so I look like I've been on vacation rather than home sick! The closest I've gotten to productive activity is cleaning the water stains off the tiles damaged by the water leak. Fun. The tile man comes tomorrow to lay the new tiles in the bathroom, jade on the floor and white up the wall around the tub (a whirlpool tub! I can't wait,). I think you have a wonderful supportive husband. That is sweet of him to worry about you getting overtired. I think though he should let you be better than him at rug hooking... it would be good for your self esteem. Growing up my sister loved rug hooking, my father called her the happy hooker. Amy I'm glad you are all letting me share my journey, it is a good outlet for me and the support I get here really helps me through this siege. Happy hooking! Patty -----Original Message-----From: holzboog@... [mailto:holzboog@...] Sent: Wednesday, July 16, 2003 2:16 PM Subject: [ ] Re: transplant newsDear Patty, Boy, this waiting part is the pitts! At least they told you someone might be ahead of you instead of you having to just wonder. My MELD score has been the same since I was listed in 3/02 and they figured with all that was happening, I would move up rather quickly. No go. A break now for 3 months from infections has given me a chance to build up some stamina and that feels great. I teach first grade so I don't imagine they would approve of that at all but I have been wondering if I could handle a couple of hours every other day. I know the personnel director would help all he could but it's a big decision after two years where I absolutely couldn't work. I intend to talk with the docs next week to get their opinion but my husband thinks I would just get over tired and start the infections again - a Catch 22. The money would be nice but not if I can't continue, so I understand your dilema - that 45 minutes of commute sounds awful. I've taken up knitting and rug hooking to keep my brain and fine motor skills from fading out. I do love the creative outlet and have made some wonderful friends in my classes. My husband took up the rug hooking, too. I think it has helped him with dealing with the stress- the worst part is that he is much better than I! I keep you in my thoughts and appreciate you letting us share your journey.Amy Quote Link to comment Share on other sites More sharing options...
Guest guest Posted July 18, 2003 Report Share Posted July 18, 2003 oooooo...can't wait to see the pictures! debby RE: [ ] Re: transplant news Hi Amy, Since you had that bout with infections... the hard part is you work with kids. I can tell my students and colleagues to stay away from me if they have a cold but yours may not be careful to cover their mouth & nose when they cough & sneeze and wash their hands. Every semester I tell my students I am immunosuppressed and to sit in the back if they have a cold and let me know if they need to come to my office or whatever. There is always at least one student who will call & tell me 'Sorry I missed class today, I have a cold and didn't want to give it to you". Great excuse, it doesn't work though. They are not EXCUSED from class, I just want them to sit away from me! I need to do some OT for myself. I never thought it would be this long, If someone had told me 3 months I would have approached this much differently than thinking it was any day. I have been doing my exercises in the pool every day, I actually have quite a good tan so I look like I've been on vacation rather than home sick! The closest I've gotten to productive activity is cleaning the water stains off the tiles damaged by the water leak. Fun. The tile man comes tomorrow to lay the new tiles in the bathroom, jade on the floor and white up the wall around the tub (a whirlpool tub! I can't wait,). I think you have a wonderful supportive husband. That is sweet of him to worry about you getting overtired. I think though he should let you be better than him at rug hooking... it would be good for your self esteem. Growing up my sister loved rug hooking, my father called her the happy hooker. Amy I'm glad you are all letting me share my journey, it is a good outlet for me and the support I get here really helps me through this siege. Happy hooking! Patty -----Original Message-----From: holzboog@... [mailto:holzboog@...] Sent: Wednesday, July 16, 2003 2:16 PM Subject: [ ] Re: transplant newsDear Patty, Boy, this waiting part is the pitts! At least they told you someone might be ahead of you instead of you having to just wonder. My MELD score has been the same since I was listed in 3/02 and they figured with all that was happening, I would move up rather quickly. No go. A break now for 3 months from infections has given me a chance to build up some stamina and that feels great. I teach first grade so I don't imagine they would approve of that at all but I have been wondering if I could handle a couple of hours every other day. I know the personnel director would help all he could but it's a big decision after two years where I absolutely couldn't work. I intend to talk with the docs next week to get their opinion but my husband thinks I would just get over tired and start the infections again - a Catch 22. The money would be nice but not if I can't continue, so I understand your dilema - that 45 minutes of commute sounds awful. I've taken up knitting and rug hooking to keep my brain and fine motor skills from fading out. I do love the creative outlet and have made some wonderful friends in my classes. My husband took up the rug hooking, too. I think it has helped him with dealing with the stress- the worst part is that he is much better than I! I keep you in my thoughts and appreciate you letting us share your journey.Amy Quote Link to comment Share on other sites More sharing options...
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