Guest guest Posted January 9, 2001 Report Share Posted January 9, 2001 > This article (http://www.msnews.org/embvitd.htm) also mentions that " MS > and other autoimmune diseases are most common in areas where the dietary > regimen contains a dominance of pro-inflammatory food types and a > paucity of anti-inflammatory nutrients " . > > These are the immune regulating effects of vitamin D: > > 1. Suppresses antibody production by B cells and the proliferation of T > cells in the thymus (Yang et al, 1993). > 2. Upregulates cytokines TGF-beta and IL-4. These proteins, which are > produced by immune cells, act as suppressants of inflammatory T cells > (Cantorna et al, 1998b). > 3. Inhibits production of pro-inflammatory cytokines such as IL-1, IL-2, > TNF and IFN gamma (Muller and Bendtzen, 1996) which also reduces > inflamammatory reactions. > 4. Interferes with T helper function and inhibits the passive transfer > of cellular immunity by Th in vivo (set, 1994) > 5. Inhibits the production of NO (nitric oxide) by immune cells (Garrion > et al, 1997). NO has been identified as one of the most destructive > products of the immune system and is an important factor in > demyelination. > 6. Inhibits the proliferation of activated and memory T cells (Muller > and Bendtzen, 1992). Such cells are the main mediators of the > inflammatory autoimmune reactions of MS. > 7. Exerts immunomodulating effects in the CNS by inducing a profound > downregulation of antigen expression by both infiltrating and resident > antigen presenting cells (e.g. macrophages) (Nataf et al, 1996). > > Phytosterols have been said to reduce cytokine inflammation. Quote Link to comment Share on other sites More sharing options...
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