Guest guest Posted April 15, 2003 Report Share Posted April 15, 2003 In a message dated 4/15/2003 9:58:35 AM Pacific Daylight Time, karlynn17@... writes: > Hi, I sent this same e mail last night, but it didn't seem to go through. > Can anyone explain RT3 to me? thanks for any info. > Dear , The hypothalamus stimulates the thyroid gland through Thyroid Stimulating Hormone (TSH) to produce T4 (thyroxine) which is a precursor hormone or raw material form of thyroid hormone. T4 is then converted into the active hormone, T3 (liothyronine), through a process of deiodinazation. T4 is also converted to RT3 (reverse T3), which is physiologically inactive. Under stress (acute and chronic illness, fasting, glucocorticoids, propylthiouracil, surgery, childbirth), more T4 is converted to RT3 (most inactive form) than to T3 (most active form) to conserve energy. With less T3 the body's cells (heat, enzyme, hormone, hair, production, etc.) slow down. This is a normal survival process. When undergoing significant physical or emotional stress, the body's conversion of T4 to T3 can drop by as much as 50% while conversion of T4 to RT3 can increase by as much as 50%. After the period of stress has passed, the conversion of T4 to T3 is supposed to resume but sometimes it doesn't. The same enzyme that converts T4 to T3 in the deiodinization process is also needed to convert RT3 to T2. Thus, a significant build up of RT3 in the body tissues can compete with and overpower the production of T3 leaving the body in repeating spiral of too much RT3 production and too little T3 production to return the stressed or ill person to normal health. Is this what you're wanting to know? I paraphrased it from Dr. 's " Doctor's Manual " pp. 20-24. in LA Quote Link to comment Share on other sites More sharing options...
Guest guest Posted April 15, 2003 Report Share Posted April 15, 2003 Hi, I sent this same e mail last night, but it didn't seem to go through. Can anyone explain RT3 to me? thanks for any info. _________________________________________________________________ STOP MORE SPAM with the new MSN 8 and get 2 months FREE* http://join.msn.com/?page=features/junkmail Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2009 Report Share Posted March 23, 2009 Not necessarily. If a person is in early stages of Hashimotoes, then they would have hyper/hypo swings, which overall would have the effect of keeping their body weight relatively normal. > > I have been looking for information as to what a high rT3 can indicate. I have a high rT3 but I am normal body weight - don't you need to be over weight to have hypothyroidism? > Micahel > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2009 Report Share Posted March 23, 2009 Hi ! Just to add a bit to what posted...rT3 can also attach to the same receptor cells that T3 is intended to attach to, thereby blocking the cells' ability to utilize the available T3, which would then result in more hypo symptoms. Ideally, the ratio of T3 to rT3 should be about 20:1. hth, > > hi, could someone explain this to me? What exactly does it mean if you have > a high level. Any info would be appreciated. > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2009 Report Share Posted March 23, 2009 With hypothyroidism the metabolism tends to be slowed down which tends to cause weight increase. It may also make it more difficult to exercise, which exacerbates the problem. So many people who are hypo report weight gain and difficulty in weight loss or control. But not everyone who is hypo is necessarily obese. Luck, .. .. > > Posted by: " evolveto2012 " evolveto2012@... > <mailto:evolveto2012@...?Subject=%20Re%3AReverse%20T3> > evolveto2012 <evolveto2012> > > > Mon Mar 23, 2009 12:13 am (PDT) > > I have been looking for information as to what a high rT3 can > indicate. I have a high rT3 but I am normal body weight - don't you > need to be over weight to have hypothyroidism? > Micahel Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 23, 2009 Report Share Posted March 23, 2009 Micahel, You wrote: > ... - don't you need to be > over weight to have hypothyroidism? Not at all. A more common indication is high cholesterol. Chuck Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 Thank you very much, for your detailed explanation. I have another question. If one have a RT3 problem, why he/she should take T3 instead of T4 to solve it? The body also needs T4 to function, right? In case that RT3 is too much, and few real T3 in the blood, intake of T3 is for making it up directly. The body no longer relies on the T4 conversion. But what about T4 supplementation now? Fragrance > > In a message dated 4/15/2003 9:58:35 AM Pacific Daylight Time, > karlynn17@... writes: > > > Hi, I sent this same e mail last night, but it didn't seem to go through. > > Can anyone explain RT3 to me? thanks for any info. > > > > Dear , > > The hypothalamus stimulates the thyroid gland through Thyroid Stimulating > Hormone (TSH) to produce T4 (thyroxine) which is a precursor hormone or raw > material form of thyroid hormone. T4 is then converted into the active > hormone, T3 (liothyronine), through a process of deiodinazation. T4 is also > converted to RT3 (reverse T3), which is physiologically inactive. > > Under stress (acute and chronic illness, fasting, glucocorticoids, > propylthiouracil, surgery, childbirth), more T4 is converted to RT3 (most > inactive form) than to T3 (most active form) to conserve energy. With less > T3 the body's cells (heat, enzyme, hormone, hair, production, etc.) slow > down. This is a normal survival process. When undergoing significant > physical or emotional stress, the body's conversion of T4 to T3 can drop by > as much as 50% while conversion of T4 to RT3 can increase by as much as 50%. > > > After the period of stress has passed, the conversion of T4 to T3 is supposed > to resume but sometimes it doesn't. The same enzyme that converts T4 to T3 > in the deiodinization process is also needed to convert RT3 to T2. Thus, a > significant build up of RT3 in the body tissues can compete with and > overpower the production of T3 leaving the body in repeating spiral of too > much RT3 production and too little T3 production to return the stressed or > ill person to normal health. > > Is this what you're wanting to know? I paraphrased it from Dr. 's > " Doctor's Manual " pp. 20-24. > > in LA > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 Oprah is an example of someone with Hashis (although I've not seen anything that confirmed she has antibodies, only observations of onlookers suspicious of this) whose weight has been up & down. I have Hashis and have varied from being a rack of bones to way over weight...a rack of bones when I was experiencing the hyper swings (it took me 3 years to regain 5 pounds once just to get to the bottom end of the range for my height, which doctors have told me is not an accurate indicator for me because I am actually 2-3 inches shorter than I should be because of my severe scoliosis)...I am now about 5 pounds from my goal weight (top end of the previous mentioned range) after going on an extreme hypo swing. Since my thyroid has pretty well been destroyed (ultrasound showed that it was extremely tiny) and I am finally being adequately treated, I expect my weight to remain relatively steady from here on out. Over-all, my weight has remained within the normal range, with the exception of 1 severe hyper swing, and my last extreme hypo swing, which was when I was finally diagnosed...other than these 2 extremes, during the winter, I always put on 5 pounds, which always came off without effort during the spring/summer/fall. > > > > I have been looking for information as to what a high rT3 can indicate. I > have a high rT3 but I am normal body weight - don't you need to be over > weight to have hypothyroidism? > > Micahel > > > > > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 My point is that Not everyone is the Same! We all are different genetically and not every person with Hashi's or even hypo T will present with Identical symptoms. You made a statement that " If a person is in early stages of Hashimotoes, then they > would have hyper/hypo swings, which overall would have the effect of keeping > their body weight relatively normal. " That is implying that everyone will experience what You experienced. Clearly that is not the case as my example of Oprah " s experience shows. BTW, apparently she does have antibodies. -- Re: Reverse T3 Oprah is an example of someone with Hashis (although I've not seen anything that confirmed she has antibodies, only observations of onlookers suspicious of this) whose weight has been up & down. I have Hashis and have varied from being a rack of bones to way over weight...a rack of bones when I was experiencing the hyper swings (it took me 3 years to regain 5 pounds once just to get to the bottom end of the range for my height, which doctors have told me is not an accurate indicator for me because I am actually 2-3 inches shorter than I should be because of my severe scoliosis)...I am now about 5 pounds from my goal weight (top end of the previous mentioned range) after going on an extreme hypo swing. Since my thyroid has pretty well been destroyed (ultrasound showed that it was extremely tiny) and I am finally being adequately treated, I expect my weight to remain relatively steady from here on out. Over-all, my weight has remained within the normal range, with the exception of 1 severe hyper swing, and my last extreme hypo swing, which was when I was finally diagnosed...other than these 2 extremes, during the winter, I always put on 5 pounds, which always came off without effort during the spring/summer/fall. > .. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 My understanding is that the body mostly uses T4 just to make T3 and for very little if anything else. If that's not right I hope someone will correct it. That's one reason I've never understood the need to take T3 in addition to T4, as the body can normally convert T4 to T3 even without a thyroid gland. But we continue to see the reports of people who swear they do better with T3. The numbers seem to suggest it's higher than the percentage who would be expected to have a T4 to T3 conversion problem. Thanks, .. .. > > Posted by: " fragrance_seen " fragrance_seen@... > <mailto:fragrance_seen@...?Subject=%20Re%3A%20Reverse%20T3> > fragrance_seen <fragrance_seen> > > > Tue Mar 24, 2009 12:18 am (PDT) > > > Thank you very much, for your detailed explanation. > > I have another question. If one have a RT3 problem, why he/she should > take T3 instead of T4 to solve it? The body also needs T4 to function, > right? In case that RT3 is too much, and few real T3 in the blood, > intake of T3 is for making it up directly. The body no longer relies on > the T4 conversion. But what about T4 supplementation now? > > Fragrance Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 , I'm aware of the " medical intelligence " that is out there. Speaking as someone who has been hypo for many years, I've tried the synthroid T4 only with an endocrinologist who was as rigid as rebar, and even he ended up giving me T3 (cytomel) eventually. However, I prefer to take them together because the T3 works quickly, and the T4 slowly. It's sort of how a diabetic takes short and long acting insulin at the same time. Roni <>Just because something isn't seen doesn't mean it's not there<> From: <res075oh@...> Subject: Re: Reverse T3 hypothyroidism Date: Tuesday, March 24, 2009, 10:40 AM My understanding is that the body mostly uses T4 just to make T3 and for very little if anything else. If that's not right I hope someone will correct it. That's one reason I've never understood the need to take T3 in addition to T4, as the body can normally convert T4 to T3 even without a thyroid gland. But we continue to see the reports of people who swear they do better with T3. The numbers seem to suggest it's higher than the percentage who would be expected to have a T4 to T3 conversion problem. Thanks, .. .. > >     Posted by: " fragrance_seen " fragrance_seen@... >     <mailto:fragrance_seen@...?Subject=%20Re%3A%20Reverse%20T3> >      fragrance_seen <fragrance_seen> > > >      Tue Mar 24, 2009 12:18 am (PDT) > > > Thank you very much, for your detailed explanation. > > I have another question. If one have a RT3 problem, why he/she should > take T3 instead of T4 to solve it? The body also needs T4 to function, > right? In case that RT3 is too much, and few real T3 in the blood, > intake of T3 is for making it up directly. The body no longer relies on > the T4 conversion. But what about T4 supplementation now? > > Fragrance ------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 I don't convert enough T3 from my T4 only dosage. I fall out of range easily. I take more T4 and my TSH falls but still low T3. ________________________________ From: <res075oh@...> hypothyroidism Sent: Tuesday, March 24, 2009 10:40:32 AM Subject: Re: Reverse T3 My understanding is that the body mostly uses T4 just to make T3 and for very little if anything else. If that's not right I hope someone will correct it. That's one reason I've never understood the need to take T3 in addition to T4, as the body can normally convert T4 to T3 even without a thyroid gland. But we continue to see the reports of people who swear they do better with T3. The numbers seem to suggest it's higher than the percentage who would be expected to have a T4 to T3 conversion problem. Thanks, .. .. > > Posted by: " fragrance_seen " fragrance_seen > <mailto:fragrance_seen?Subject=%20Re% 3A%20Reverse% 20T3> > fragrance_seen <http://profiles. / fragrance_ seen> > > > Tue Mar 24, 2009 12:18 am (PDT) > > > Thank you very much, for your detailed explanation. > > I have another question. If one have a RT3 problem, why he/she should > take T3 instead of T4 to solve it? The body also needs T4 to function, > right? In case that RT3 is too much, and few real T3 in the blood, > intake of T3 is for making it up directly. The body no longer relies on > the T4 conversion. But what about T4 supplementation now? > > Fragrance Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 The thyroid makes both and from the point of " economy " I would think evolution would have selected against T3 production in the thyroid if it was unnecessary. I suspect that there are body tissues that do not have the ability to convert T4 to T3 but use circulating T3 as needed. Another " theory " I have is that some common modern dietary options like grains and/or trans-fats etc. somehow effect and/or limit the ability of other body tissues to convert T4 to T3. There are also lower hormone/vitamin issues in the modern diet like low vitamin D being epidemic which could play a factor. Steve wrote: > My understanding is that the body mostly uses T4 just to make T3 and for > very little if anything else. If that's not right I hope someone will > correct it. > > That's one reason I've never understood the need to take T3 in addition > to T4, as the body can normally convert T4 to T3 even without a thyroid > gland. But we continue to see the reports of people who swear they do > better with T3. The numbers seem to suggest it's higher than the > percentage who would be expected to have a T4 to T3 conversion problem. > > Thanks, > > . > . > >> Posted by: " fragrance_seen " fragrance_seen@... >> <mailto:fragrance_seen@...?Subject=%20Re%3A%20Reverse%20T3> >> fragrance_seen <fragrance_seen> >> >> >> Tue Mar 24, 2009 12:18 am (PDT) >> >> >> Thank you very much, for your detailed explanation. >> >> I have another question. If one have a RT3 problem, why he/she should >> take T3 instead of T4 to solve it? The body also needs T4 to function, >> right? In case that RT3 is too much, and few real T3 in the blood, >> intake of T3 is for making it up directly. The body no longer relies on >> the T4 conversion. But what about T4 supplementation now? >> >> Fragrance -- Steve - dudescholar4@... Take World's Smallest Political Quiz at http://www.theadvocates.org/quiz.html " If a thousand old beliefs were ruined on our march to truth we must still march on. " --Stopford Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 Haa! We just bought chocolate chips. He is going to start them right now. I also have strawberry shortcake!!!!!!!  Dad said to tell you they have EGGS in them...... From: <res075oh@...> Subject: Re: Reverse T3 hypothyroidism Date: Tuesday, March 24, 2009, 12:40 PM My understanding is that the body mostly uses T4 just to make T3 and for very little if anything else. If that's not right I hope someone will correct it. That's one reason I've never understood the need to take T3 in addition to T4, as the body can normally convert T4 to T3 even without a thyroid gland. But we continue to see the reports of people who swear they do better with T3. The numbers seem to suggest it's higher than the percentage who would be expected to have a T4 to T3 conversion problem. Thanks, .. .. > > Posted by: " fragrance_seen " fragrance_seen > <mailto:fragrance_seen?Subject=%20Re% 3A%20Reverse% 20T3> > fragrance_seen <http://profiles. / fragrance_ seen> > > > Tue Mar 24, 2009 12:18 am (PDT) > > > Thank you very much, for your detailed explanation. > > I have another question. If one have a RT3 problem, why he/she should > take T3 instead of T4 to solve it? The body also needs T4 to function, > right? In case that RT3 is too much, and few real T3 in the blood, > intake of T3 is for making it up directly. The body no longer relies on > the T4 conversion. But what about T4 supplementation now? > > Fragrance Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 I'm sure that the low vitamin D has something to do with the hypothyroid issues I have, as well as the fibromyalgia, and atrial fibrillation. I started out with a vitam D test outside the bottom of the range. Have been taking over 1000 units and it's 32. My doctor just said to take 2000, and we'll keep upping it till it's all right. I was taking 1000 mgs of magnesium, but started to have issues that suggested I was getting too much, so I cut back one 250 mg pill, and it's better. However, with the thyroid being what it is, I know I could kick over into the other direction, so I'll have to watch that.  Roni <>Just because something isn't seen doesn't mean it's not there<> > My understanding is that the body mostly uses T4 just to make T3 and for > very little if anything else. If that's not right I hope someone will > correct it. > > That's one reason I've never understood the need to take T3 in addition > to T4, as the body can normally convert T4 to T3 even without a thyroid > gland. But we continue to see the reports of people who swear they do > better with T3. The numbers seem to suggest it's higher than the > percentage who would be expected to have a T4 to T3 conversion problem. > > Thanks, > > . > . > >>     Posted by: " fragrance_seen " fragrance_seen@... >>     <mailto:fragrance_seen@...?Subject=%20Re%3A%20Reverse%20T3> >>      fragrance_seen <fragrance_seen> >> >> >>      Tue Mar 24, 2009 12:18 am (PDT) >> >> >> Thank you very much, for your detailed explanation. >> >> I have another question. If one have a RT3 problem, why he/she should >> take T3 instead of T4 to solve it? The body also needs T4 to function, >> right? In case that RT3 is too much, and few real T3 in the blood, >> intake of T3 is for making it up directly. The body no longer relies on >> the T4 conversion. But what about T4 supplementation now? >> >> Fragrance -- Steve - dudescholar4@... Take World's Smallest Political Quiz at http://www.theadvocates.org/quiz.html " If a thousand old beliefs were ruined on our march to truth we must still march on. " --Stopford ------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 wrote: > > > My understanding is that the body mostly uses T4 just to make T3 and for > very little if anything else. If that's not right I hope someone will > correct it. Nearly half of the T4 converts to RT3. An imbalance in the proportion of T3 and RT3 can effectively manifest as a conversion problem. Chuck Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 And what can be done about it? On Mar 24, 2009, at 4:54 PM, Chuck B <gumboyaya@...> wrote: wrote: > > > My understanding is that the body mostly uses T4 just to make T3 and for > very little if anything else. If that's not right I hope someone will > correct it. Nearly half of the T4 converts to RT3. An imbalance in the proportion of T3 and RT3 can effectively manifest as a conversion problem. Chuck Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 wrote: > > > And what can be done about it? Increase T3 intake until the condition changes. Chuck Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 Roni, my post was in response to Fragrance's question and was intended to reflect my understand [and some lack of understanding] of the general way that T4 and T3 are coordinated. I'm sure some individuals will fall outside the norm even if I should happen to have all the facts straight; which is unlikely. .. .. > > Posted by: " Roni Molin " matchermaam@... > <mailto:matchermaam@...?Subject=%20Re%3A%20Reverse%20T3> > matchermaam <matchermaam> > > > Tue Mar 24, 2009 12:45 pm (PDT) > > , I'm aware of the " medical intelligence " that is out there. > Speaking as someone > who has been hypo for many years, I've tried the synthroid T4 only > with an endocrinologist who was as rigid as rebar, and even he ended > up giving me T3 (cytomel) eventually. However, I prefer to take them > together because the T3 works quickly, and the T4 slowly. It's sort of > how a diabetic takes short and long acting insulin at the same time. > > Roni > <>Just because something > isn't seen doesn't mean it's > not there<> > > > > From: <res075oh@... <mailto:res075oh%40verizon.net>> > Subject: Re: Reverse T3 > hypothyroidism > <mailto:hypothyroidism%40> > Date: Tuesday, March 24, 2009, 10:40 AM > > My understanding is that the body mostly uses T4 just to make T3 and for > very little if anything else. If that's not right I hope someone will > correct it. > > That's one reason I've never understood the need to take T3 in addition > to T4, as the body can normally convert T4 to T3 even without a thyroid > gland. But we continue to see the reports of people who swear they do > better with T3. The numbers seem to suggest it's higher than the > percentage who would be expected to have a T4 to T3 conversion problem. > > Thanks, > > . > . > > > > > Posted by: " fragrance_seen " fragrance_seen@... > <mailto:fragrance_seen%40> > > <mailto:fragrance_seen@... > <mailto:fragrance_seen%40>?Subject=%20Re% > 3A%20Reverse%20T3> > > fragrance_seen <fragrance_seen > <fragrance_seen>> > > > > > > Tue Mar 24, 2009 12:18 am (PDT) > > > > > > Thank you very much, for your detailed explanation. > > > > I have another question. If one have a RT3 problem, why he/she should > > take T3 instead of T4 to solve it? The body also needs T4 to function, > > right? In case that RT3 is too much, and few real T3 in the blood, > > intake of T3 is for making it up directly. The body no longer relies on > > the T4 conversion. But what about T4 supplementation now? > > > > Fragrance Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 You'd expect " economy " in human evolution but you'll find lots of instances in the human body which demonstrate the opposite. At least according to an article I recently read. Darned if I can place my hands on it now... .. .. > > Posted by: " Steve " dudescholar4@... > <mailto:dudescholar4@...?Subject=%20Re%3A%20Reverse%20T3> > dudescholar <dudescholar> > > > Tue Mar 24, 2009 1:45 pm (PDT) > > The thyroid makes both and from the point of " economy " I would think > evolution would have selected against T3 production in the thyroid if it > was unnecessary. I suspect that there are body tissues that do not have > the ability to convert T4 to T3 but use circulating T3 as needed. > > Another " theory " I have is that some common modern dietary options like > grains and/or trans-fats etc. somehow effect and/or limit the ability of > other body tissues to convert T4 to T3. > > There are also lower hormone/vitamin issues in the modern diet like low > vitamin D being epidemic which could play a factor. > > Steve > > wrote: > > My understanding is that the body mostly uses T4 just to make T3 and > for > > very little if anything else. If that's not right I hope someone will > > correct it. > > > > That's one reason I've never understood the need to take T3 in addition > > to T4, as the body can normally convert T4 to T3 even without a thyroid > > gland. But we continue to see the reports of people who swear they do > > better with T3. The numbers seem to suggest it's higher than the > > percentage who would be expected to have a T4 to T3 conversion problem. > > > > Thanks, > > > > . > > . > > > >> Posted by: " fragrance_seen " fragrance_seen@... > <mailto:fragrance_seen%40> > >> <mailto:fragrance_seen@... > <mailto:fragrance_seen%40>?Subject=%20Re% > 3A%20Reverse%20T3> > >> fragrance_seen <fragrance_seen > <fragrance_seen>> > >> > >> > >> Tue Mar 24, 2009 12:18 am (PDT) > >> > >> > >> Thank you very much, for your detailed explanation. > >> > >> I have another question. If one have a RT3 problem, why he/she should > >> take T3 instead of T4 to solve it? The body also needs T4 to function, > >> right? In case that RT3 is too much, and few real T3 in the blood, > >> intake of T3 is for making it up directly. The body no longer relies on > >> the T4 conversion. But what about T4 supplementation now? > >> > >> Fragrance Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 24, 2009 Report Share Posted March 24, 2009 Which means exactly what??? .. .. > > Posted by: " Carol " nelsonck@... > <mailto:nelsonck@...?Subject=%20Re%3A%20Reverse%20T3> > venizia1948 <venizia1948> > > > Tue Mar 24, 2009 5:09 pm (PDT) > > Haa! We just bought chocolate chips. He is going to start them right > now. I also have strawberry shortcake!!! > !!!! Dad said to tell you they have EGGS in them...... > > > From: <res075oh@... <mailto:res075oh%40verizon.net>> > Subject: Re: Reverse T3 > hypothyroidism > <mailto:hypothyroidism%40> > Date: Tuesday, March 24, 2009, 12:40 PM > > My understanding is that the body mostly uses T4 just to make T3 and for > > very little if anything else. If that's not right I hope someone will > > correct it. > > That's one reason I've never understood the need to take T3 in addition > > to T4, as the body can normally convert T4 to T3 even without a thyroid > > gland. But we continue to see the reports of people who swear they do > > better with T3. The numbers seem to suggest it's higher than the > > percentage who would be expected to have a T4 to T3 conversion problem. > > Thanks, > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Oops! Sorry, sometimes it's hard to tell who is responding to what. Roni <>Just because something isn't seen doesn't mean it's not there<> > > From: <res075oh@... <mailto:res075oh%40verizon.net>> > Subject: Re: Reverse T3 > hypothyroidism > <mailto:hypothyroidism%40> > Date: Tuesday, March 24, 2009, 10:40 AM > > My understanding is that the body mostly uses T4 just to make T3 and for > very little if anything else. If that's not right I hope someone will > correct it. > > That's one reason I've never understood the need to take T3 in addition > to T4, as the body can normally convert T4 to T3 even without a thyroid > gland. But we continue to see the reports of people who swear they do > better with T3. The numbers seem to suggest it's higher than the > percentage who would be expected to have a T4 to T3 conversion problem. > > Thanks, > > . > . > > > > >     Posted by: " fragrance_seen " fragrance_seen@... > <mailto:fragrance_seen%40> > >     <mailto:fragrance_seen@... > <mailto:fragrance_seen%40>?Subject=%20Re% > 3A%20Reverse%20T3> > >      fragrance_seen <fragrance_seen > <fragrance_seen>> > > > > > >      Tue Mar 24, 2009 12:18 am (PDT) > > > > > > Thank you very much, for your detailed explanation. > > > > I have another question. If one have a RT3 problem, why he/she should > > take T3 instead of T4 to solve it? The body also needs T4 to function, > > right? In case that RT3 is too much, and few real T3 in the blood, > > intake of T3 is for making it up directly. The body no longer relies on > > the T4 conversion. But what about T4 supplementation now? > > > > Fragrance ------------------------------------ Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Hi Nancie! That is precisely why I qualified my statement, in advance, by opening with " Not necessarily! " Micahel appeared to be under the presumption that one had to be over-weight in order to be hypoT. My point was that many people, with Hashis, begin life with normal weight, and maintain relatively normal weight, often with small swings, but still relatively normal, until their thyroid is destroyed to the point that it can no longer produce enough thyroid hormone to meet their needs; then people " usually " (I will state that this time) begin to put on weight that is difficult, if not impossible, to take off until their thyroid is adequately treated. Once again, using myself as an example, I got so frustrated that about 6 months ago, I cut down to less than 700 calories a day for a good 2 months and still only lost 2 or 3 pounds. Once my doctor finally increased my thyroid med, and I had worked my way up to tolerate the increase, the weight came off without effort...mostly in the form of pee; I obviously had lots of water retention throughout my entire body being stored within mucin...something Dr. Mark Starr discusses in his book, " Hypothyroidism Type 2 The Epidemic " . Regarding Oprah, I agree, she probably does have Hashis antibodies, but this has never been stated publicly, to my knowledge. Also, I am old enough to remember the days when Oprah's show first came to television and she did NOT have any obvious weight problems back in those days. Have a great day... > > My point is that Not everyone is the Same! We all are different genetically > and not every person with Hashi's or even hypo T will present with Identical > symptoms. > You made a statement that " If a person is in early stages of Hashimotoes, > then they > > would have hyper/hypo swings, which overall would have the effect of > keeping > > their body weight relatively normal. " > That is implying that everyone will experience what You experienced. Clearly > that is not the case as my example of Oprah " s experience shows. > BTW, apparently she does have antibodies. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Hi Fragrance! Because T4 is a storage hormone, available to convert to rT3 or T3, depending on what the body happens to do with it. T3 is the most active hormone the body needs and uses. Since rT3 can block receptor cells, by taking T3 only, there is no additional T4 being provided to convert to rT3, which makes it so the rT3 can clear out and the T3 is then able to attach to those cells. hth, > > ...If one have a RT3 problem, why he/she should > take T3 instead of T4 to solve it? The body also needs T4 to function, > right? In case that RT3 is too much, and few real T3 in the blood, > intake of T3 is for making it up directly. The body no longer relies on > the T4 conversion. But what about T4 supplementation now? > > Fragrance Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 25, 2009 Report Share Posted March 25, 2009 Weight has always been a fight for me, and I've had hypo for over 50 years. As far as Oprah, she has always been fighting her weight. At one point, on some liquid diet she was on, she went down to a size 10 and looked terrific for a time. It alway came back though. Each time she loses, she thinks she's fournd the magic land, but then it comes back. It's one of the reasons so many women can relate to her. All of us with weight problems try, try and try over and over again. I will say though that I never got as heavy as she gets. I guess she's good at staying in denial for a longer time than me. Roni <>Just because something isn't seen doesn't mean it's not there<> From: cindy.seeley <cindy.seeley@...> Subject: Re: Reverse T3 hypothyroidism Date: Wednesday, March 25, 2009, 4:40 AM Hi Nancie! That is precisely why I qualified my statement, in advance, by opening with " Not necessarily! "  Micahel appeared to be under the presumption that one had to be over-weight in order to be hypoT. My point was that many people, with Hashis, begin life with normal weight, and maintain relatively normal weight, often with small swings, but still relatively normal, until their thyroid is destroyed to the point that it can no longer produce enough thyroid hormone to meet their needs; then people " usually " (I will state that this time) begin to put on weight that is difficult, if not impossible, to take off until their thyroid is adequately treated. Once again, using myself as an example, I got so frustrated that about 6 months ago, I cut down to less than 700 calories a day for a good 2 months and still only lost 2 or 3 pounds. Once my doctor finally increased my thyroid med, and I had worked my way up to tolerate the increase, the weight came off without effort...mostly in the form of pee; I obviously had lots of water retention throughout my entire body being stored within mucin...something Dr. Mark Starr discusses in his book, " Hypothyroidism Type 2 The Epidemic " . Regarding Oprah, I agree, she probably does have Hashis antibodies, but this has never been stated publicly, to my knowledge. Also, I am old enough to remember the days when Oprah's show first came to television and she did NOT have any obvious weight problems back in those days. Have a great day... > > My point is that Not everyone is the Same! We all are different genetically > and not every person with Hashi's or even hypo T will present with Identical > symptoms. > You made a statement that " If a person is in early stages of Hashimotoes, > then they > > would have hyper/hypo swings, which overall would have the effect of > keeping > > their body weight relatively normal. " > That is implying that everyone will experience what You experienced. Clearly > that is not the case as my example of Oprah " s experience shows. > BTW, apparently she does have antibodies. ------------------------------------ Quote Link to comment Share on other sites More sharing options...
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