I'm in a pickle - need some answers - please!

[Guest guest]

Hi everyone;

I got back from the GI today. Not very good news. I need your input on

some questions.

Has any one seen their liver not respond to prednisone over time?

Meaning, where 20mg of prednisone use to knock your AST/ALT numbers down

to normal, now that amount of prednisone doesn't work as well?

Has any one had a Pro-Predict Metabolite (thiopurine therapy) Level

Monitoring Test done? It's a blood test where they see if the imuran is

at a therapeutic level?

Has any one had their A1C numbers come down (without diabetic treatment)

from a reduction of the prednisone?

I know these are tough questions, but I'm in a pickle.

My A1C came back today at 11.3 (non diabetic is a value less than 6.5).

We can't raise the prednisone to help the liver numbers because it's the

prednisone that's causing the A1C numbers to go up (pretty quickly).

So, we are lowering the prednisone to 15mg to see if it will help the

glucose. But, that will probably mean my liver numbers will go up. In

one month, I have seen (under 15mg) my numbers go from normal to over

100 each.

I'm in a catch-22.

Thanks for any one and everyone in helping me understand!

Sue AIH 12/98

Colorado