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Re: biopsy with AIH

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This is a general question to the group.

When you had your biopsy did the doctors say they could tell from the biopsy

that you have AIH? My GI doctor said no. But in my reading there is a

different pattern of inlammation. Also, I know some of us have diagnosis of

cirrhosis. If your biopsy says cirrhosis wouldn't it be more difficult to

determine AIH? I see Dr. Czaja in August and am just curious about others

biopsies.

Thanks again

Susie

One more question can you have a positive ANA and not have AIH? or any

autoimmune disease.

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With my two biopsies they said it had AIH. How I don't know and I guess I

didn't want to know. Next time I will ask. I know my liver is still pretty

good but it is only time when it can get worse.

Sue

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Don

Did you have the positive ANA? How high was it? Mine right now is only

1:320 and from my understanding it is not that high. But my biopsy also

says cirrhosis so would the ANA be less prominent at that point? It is so

confusing. I just don't understand how I could develop cirrhosis and have

moderate active inflammation when I've never drank or did any drugs.

Thanks

Susie

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Lori

Thanks for all the info. My ANA is not that high. But with a biopsy that

says cirrhosis part of me feels like I need to go to Mayo and then another

part of me thinks not. I feel OK for now. Mainly a lot of

fatigue,depression etc-but nothing that feels life threatening. I guess I'm

in a little bit of denial!? I have had a lot of health problems the last few

years so maybe the appointment won't be for nothing. I just feel like I'm

wasting their time. I guess I just need to hear some validation that it is

Ok to get another opinion.

Thanks for listening.

Susie

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Hi Susie,

The biopsy is one of several pieces necessary to diagnose AIH.

Unfortunately, there is no definitive test. Diagnosis is made by considering

a variety of factors, including blood tests and symptoms. Diagnosing

autoimmune diseases is as much art as science. That is because most

autoimmune diseases present in very different ways for each patient. Not

everyone has the same symptoms, antibodies, or biopsy results. For example,

my biopsy looks more like damage from a medication reaction than from AIH,

but other factors are more indicative of AIH.

Positive ANA's are nearly always seen in autoimmune disease. However ANA can

become positive from aging, viral infections, and some prescription drugs.

However, levels greater than 1:1280 almost always indicate an autoimmune

disorder.

HTH.

Don

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Susie, a person will develop cirrhosis when the liver becomes so damaged

that it can no longer repair itself. Then the liver becomes scarred and will

begin to shrink and will eventually shut down in the late stages of

cirrhosis. That is a very common conception that has been around a long

time, that you only develop cirrhosis from too much alcohol or drugs or

both. Well in Autoimmune hepatitis and primary bilarary cirrhosis and

primarary sclerosing colangitis, it is a person's own immune system, that

for some unknown reason, decides to attack the liver or the liver bile ducts

or both, causing the cirrhosis.

I know when I was diagnosed with AIH with cirrhosos, it was like, " HELLO,

HOW DID I GET CIRRHOSIS WHEN I HARDLY DRINK AND DON " T DO DRUGS? " It is a

heard pill to swallow when you get such a diagnosis. I was in denial for a

while. But I overcame the shock and moved on.

Hope this helps!!! Lori C. AIH with Cirrhosis & transplant 3~11~97

Re: [ ] biopsy with AIH

>From: SUSIE22658@...

>

>Don

>Did you have the positive ANA? How high was it? Mine right now is only

>1:320 and from my understanding it is not that high. But my biopsy also

>says cirrhosis so would the ANA be less prominent at that point? It is so

>confusing. I just don't understand how I could develop cirrhosis and have

>moderate active inflammation when I've never drank or did any drugs.

>Thanks

>Susie

>

>---------------------------

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Hi Susie,

At one time my ANA was 1:640. I was also positive for anti-smooth muscle

antibodies. My most recent tests, however, are negative for both. Talk about

confusing!

As far as what a doc will give the most weight to, that is where the art

comes in. Some are strictly numbers, others are mostly symptoms. I prefer

someone who looks at the total picture.

It is confusing. But then, if it wasn't, why would we need to big buck

docs??

Don

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Susie, I forgot to mention, I had an ANA of about 1:1,350 when I was

diagnosed, now after transplant it is 1:12. I also tested positive for the

smooth muscle antibody. That together with my symptoms that I had finally

led me to my diagnosis. I went undiagnosed for years by my local Drs. It was

finally an oncologist (cancer DR.) that saw me and read my chart and looked

at me and said I had AIH w/ cirrhosis. Then he sent me to Dr. Czaja & Dr.

Marotta, the GI Drs. at Mayo in Rochester, Mn. Hope this helps. Lori C.

AIH w/ cirrhosis ~transplanted 3~11~97

Re: [ ] biopsy with AIH

>From: SUSIE22658@...

>

>Don

>Did you have the positive ANA? How high was it? Mine right now is only

>1:320 and from my understanding it is not that high. But my biopsy also

>says cirrhosis so would the ANA be less prominent at that point? It is so

>confusing. I just don't understand how I could develop cirrhosis and have

>moderate active inflammation when I've never drank or did any drugs.

>Thanks

>Susie

>

>---------------------------

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Lori:

How do you like Dr. Czaja? I really respect him. He is not to busy to see my

when I go down there. Yes he has other doctors ask the questions, but then

he comes in and does the exam and questions again.

Sue AIH

Wisconsin

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Susie, I would say go to Mayo for the 2nd opinion. If you have any doubts,

that would be your best bet. I know I did not feel that it was life

threatening for me either, I was over weight and had been all my life, and

just figured it was blood pressure or my heart, then I finally went to my

local doc and all my blood levels were so low, they sent me to Mayo for bone

marrow biopsy to see if I had Leukemia, and then it took Mayo about 3 1/2

weeks to figure out that it was AIH. Even though my liver enzymes had been

elevated for years. At least since 1989, when I was 22.

It's real hard to accept that you may have a chronic disease, but once you

get to that point of acceptance, it becomes so much easier. I'm not gonna

preach God to anyone, but I have to say that the only way that I came to

acceptance of my disease and made it through my transplant process & am still

going on today is through my faith. My pastor & my church were so very good

to me throughout the whole thing. God has truly been good to me. How many

people can say that after going through such a traumatic experience? I

really would not change anything, I have learned so much and met so many

wonderful people along this journey. In a real way it has almost been a

blessing. Go figure!! Please keep your chin up and I will be praying for

you.

Lori C. Liver TX 3~11~97 Remember " No one should go through this

alone " TTFN

Re: [ ] biopsy with AIH

>From: SUSIE22658@...

>

>Lori

>Thanks for all the info. My ANA is not that high. But with a biopsy that

>says cirrhosis part of me feels like I need to go to Mayo and then another

>part of me thinks not. I feel OK for now. Mainly a lot of

>fatigue,depression etc-but nothing that feels life threatening. I guess

I'm

>in a little bit of denial!? I have had a lot of health problems the last

few

>years so maybe the appointment won't be for nothing. I just feel like I'm

>wasting their time. I guess I just need to hear some validation that it is

>Ok to get another opinion.

>Thanks for listening.

>Susie

>

>---------------------------

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I really liked him, although I did deal more with Dr. Marotta. Dr. Marotta

is from Canada. Dr Czaja was real thorough though. I was sent over to him to

confirme my AIH diagnosis which was made by an oncologist there from Mayo,

Dr. Letendre. I thank God for all of them. i do not think i would be here

without them:)

Re: [ ] biopsy with AIH

>From: Roselle50@...

>

>Lori:

>

>How do you like Dr. Czaja? I really respect him. He is not to busy to see

my

>when I go down there. Yes he has other doctors ask the questions, but then

>he comes in and does the exam and questions again.

>

>Sue AIH

>Wisconsin

>

>---------------------------

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Hi all,

I am going to pre-op laparoscopy biopsy tomorrow at 3:45 pm New Jerseu time.

Wish me well and those of you who pray, pray for accuracy please.

>From: SUSIE22658@...

>Reply- onelist

> onelist

>Subject: Re: [ ] biopsy with AIH

>Date: Fri, 9 Jul 1999 10:58:59 EDT

>MIME-Version: 1.0

>From errors-165537-2820-shireen42=hotmail.comonelist Fri Jul 9

>07:59:20 1999

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>

>From: SUSIE22658@...

>

>This is a general question to the group.

>When you had your biopsy did the doctors say they could tell from the

>biopsy

>that you have AIH? My GI doctor said no. But in my reading there is a

>different pattern of inlammation. Also, I know some of us have diagnosis

>of

>cirrhosis. If your biopsy says cirrhosis wouldn't it be more difficult to

>determine AIH? I see Dr. Czaja in August and am just curious about others

>biopsies.

>Thanks again

>Susie

>One more question can you have a positive ANA and not have AIH? or any

>autoimmune disease.

>

>---------------------------

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My prayers are with you.... Just relax and stay focused. Everything will go

smoothly and you will be very relieved. I have been throught it... we all

have... You will do fine...

We are with you. Love and Light Dixie

susan johnson wrote:

> From: " susan johnson " <shireen42@...>

>

> Hi all,

>

> I am going to pre-op laparoscopy biopsy tomorrow at 3:45 pm New Jerseu time.

> Wish me well and those of you who pray, pray for accuracy please.

>

>

>

> >From: SUSIE22658@...

> >Reply- onelist

> > onelist

> >Subject: Re: [ ] biopsy with AIH

> >Date: Fri, 9 Jul 1999 10:58:59 EDT

> >MIME-Version: 1.0

> >From errors-165537-2820-shireen42=hotmail.comonelist Fri Jul 9

> >07:59:20 1999

> >Received: (qmail 13659 invoked by alias); 9 Jul 1999 14:58:51 -0000

> >Received: (qmail 13609 invoked from network); 9 Jul 1999 14:58:50 -0000

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> > -owneronelist

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> >Precedence: bulk

> >List-Unsubscribe: <mailto: -unsubscribeONElist>

> >

> >From: SUSIE22658@...

> >

> >This is a general question to the group.

> >When you had your biopsy did the doctors say they could tell from the

> >biopsy

> >that you have AIH? My GI doctor said no. But in my reading there is a

> >different pattern of inlammation. Also, I know some of us have diagnosis

> >of

> >cirrhosis. If your biopsy says cirrhosis wouldn't it be more difficult to

> >determine AIH? I see Dr. Czaja in August and am just curious about others

> >biopsies.

> >Thanks again

> >Susie

> >One more question can you have a positive ANA and not have AIH? or any

> >autoimmune disease.

> >

> >---------------------------

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Dear Jody:

Although I don't know what makes a doctor choose one method or the other, my

hepatologist just told me the other day that a biopsy done laparoscopally

(sp) was the best route because that way they can see the damage to liver,

whereas when they do a needle biopsy, they are just looking at one tiny

section and it might not be indicative of the entire 'liver picture.'

Kathy (AIH)

Seattle area

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I have a question..There seems to be two ways to do

liver bx..either puncture thru the abdominal wall or

laproscopically.. Does anyone know why a doctor picks

one way over the other to do the bx?? I think I'd

rather be unconcious myself..

Jody

===

ISO B-family

DOB 5-23-61

b-name: Compton

*VOTE TO RE-ESTABLISH ADOPTEES RIGHTS TO KNOW THEIR

FAMILIES**

---susan johnson <shireen42@...> wrote:

>

> From: " susan johnson " <shireen42@...>

>

> Hi all,

>

> I am going to pre-op laparoscopy biopsy tomorrow at

3:45 pm New Jerseu time.

> Wish me well and those of you who pray, pray for

accuracy please.

>

>

>

>

> >From: SUSIE22658@...

> >Reply- onelist

> > onelist

> >Subject: Re: [ ] biopsy with AIH

> >Date: Fri, 9 Jul 1999 10:58:59 EDT

> >MIME-Version: 1.0

> >From

errors-165537-2820-shireen42=hotmail.comonelist

Fri Jul 9

> >07:59:20 1999

> >Received: (qmail 13659 invoked by alias); 9 Jul

1999 14:58:51 -0000

> >Received: (qmail 13609 invoked from network); 9

Jul 1999 14:58:50 -0000

> >Received: from unknown (HELO imo12.mx.aol.com)

(198.81.17.2) by

> >pop.onelist.com with SMTP; 9 Jul 1999 14:58:50 -0000

> >Received: from SUSIE22658@... by

imo12.mx.aol.com (IMOv20.21) id

> >hECPa05367 (4447) for

< onelist>; Fri, 9 Jul 1999

> >10:58:59 -0400 (EDT)

> >Message-ID: <1956ca79.24b76833@...>

> >X-Mailer: Windows AOL sub 24

> >Mailing-List: list onelist;

contact

> > -owneronelist

> >Delivered-mailing list

onelist

> >Precedence: bulk

> >List-Unsubscribe:

<mailto: -unsubscribeONElist>

> >

> >From: SUSIE22658@...

> >

> >This is a general question to the group.

> >When you had your biopsy did the doctors say they

could tell from the

> >biopsy

> >that you have AIH? My GI doctor said no. But in

my reading there is a

> >different pattern of inlammation. Also, I know

some of us have diagnosis

> >of

> >cirrhosis. If your biopsy says cirrhosis wouldn't

it be more difficult to

> >determine AIH? I see Dr. Czaja in August and am

just curious about others

> >biopsies.

> >Thanks again

> >Susie

> >One more question can you have a positive ANA and

not have AIH? or any

> >autoimmune disease.

> >

> >---------------------------

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Guest guest

I have a question..There seems to be two ways to do

liver bx..either puncture thru the abdominal wall or

laproscopically.. Does anyone know why a doctor picks

one way over the other to do the bx?? I think I'd

rather be unconcious myself..

Jody

===

ISO B-family

DOB 5-23-61

b-name: Compton

*VOTE TO RE-ESTABLISH ADOPTEES RIGHTS TO KNOW THEIR

FAMILIES**

---susan johnson <shireen42@...> wrote:

>

> From: " susan johnson " <shireen42@...>

>

> Hi all,

>

> I am going to pre-op laparoscopy biopsy tomorrow at

3:45 pm New Jerseu time.

> Wish me well and those of you who pray, pray for

accuracy please.

>

>

>

>

> >From: SUSIE22658@...

> >Reply- onelist

> > onelist

> >Subject: Re: [ ] biopsy with AIH

> >Date: Fri, 9 Jul 1999 10:58:59 EDT

> >MIME-Version: 1.0

> >From

errors-165537-2820-shireen42=hotmail.comonelist

Fri Jul 9

> >07:59:20 1999

> >Received: (qmail 13659 invoked by alias); 9 Jul

1999 14:58:51 -0000

> >Received: (qmail 13609 invoked from network); 9

Jul 1999 14:58:50 -0000

> >Received: from unknown (HELO imo12.mx.aol.com)

(198.81.17.2) by

> >pop.onelist.com with SMTP; 9 Jul 1999 14:58:50 -0000

> >Received: from SUSIE22658@... by

imo12.mx.aol.com (IMOv20.21) id

> >hECPa05367 (4447) for

< onelist>; Fri, 9 Jul 1999

> >10:58:59 -0400 (EDT)

> >Message-ID: <1956ca79.24b76833@...>

> >X-Mailer: Windows AOL sub 24

> >Mailing-List: list onelist;

contact

> > -owneronelist

> >Delivered-mailing list

onelist

> >Precedence: bulk

> >List-Unsubscribe:

<mailto: -unsubscribeONElist>

> >

> >From: SUSIE22658@...

> >

> >This is a general question to the group.

> >When you had your biopsy did the doctors say they

could tell from the

> >biopsy

> >that you have AIH? My GI doctor said no. But in

my reading there is a

> >different pattern of inlammation. Also, I know

some of us have diagnosis

> >of

> >cirrhosis. If your biopsy says cirrhosis wouldn't

it be more difficult to

> >determine AIH? I see Dr. Czaja in August and am

just curious about others

> >biopsies.

> >Thanks again

> >Susie

> >One more question can you have a positive ANA and

not have AIH? or any

> >autoimmune disease.

> >

> >---------------------------

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Guest guest

Jody,

Doctors often choose laparoscopy because can get a look at the liver and get

a piece that is definetly what they want rather than a chance piece picked

up by a needle.

>From: Jody Compton <intrigued1@...>

>Reply- onelist

> onelist, onelist

>Subject: Re: [ ] biopsy with AIH

>Date: Thu, 15 Jul 1999 10:35:42 -0700 (PDT)

>MIME-Version: 1.0

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>From: Jody Compton <intrigued1@...>

>

>I have a question..There seems to be two ways to do

>liver bx..either puncture thru the abdominal wall or

>laproscopically.. Does anyone know why a doctor picks

>one way over the other to do the bx?? I think I'd

>rather be unconcious myself..

>Jody

>

>

>

>===

>ISO B-family

>DOB 5-23-61

>b-name: Compton

>*VOTE TO RE-ESTABLISH ADOPTEES RIGHTS TO KNOW THEIR

>FAMILIES**

>

>

>

>

>

>

>---susan johnson <shireen42@...> wrote:

> >

> > From: " susan johnson " <shireen42@...>

> >

> > Hi all,

> >

> > I am going to pre-op laparoscopy biopsy tomorrow at

>3:45 pm New Jerseu time.

> > Wish me well and those of you who pray, pray for

>accuracy please.

> >

> >

> >

> >

> > >From: SUSIE22658@...

> > >Reply- onelist

> > > onelist

> > >Subject: Re: [ ] biopsy with AIH

> > >Date: Fri, 9 Jul 1999 10:58:59 EDT

> > >MIME-Version: 1.0

> > >From

>errors-165537-2820-shireen42=hotmail.comonelist

>Fri Jul 9

> > >07:59:20 1999

> > >Received: (qmail 13659 invoked by alias); 9 Jul

>1999 14:58:51 -0000

> > >Received: (qmail 13609 invoked from network); 9

>Jul 1999 14:58:50 -0000

> > >Received: from unknown (HELO imo12.mx.aol.com)

>(198.81.17.2) by

> > >pop.onelist.com with SMTP; 9 Jul 1999 14:58:50 -0000

> > >Received: from SUSIE22658@... by

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>< onelist>; Fri, 9 Jul 1999

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> > >X-Mailer: Windows AOL sub 24

> > >Mailing-List: list onelist;

>contact

> > > -owneronelist

> > >Delivered-mailing list

> onelist

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> > >List-Unsubscribe:

><mailto: -unsubscribeONElist>

> > >

> > >From: SUSIE22658@...

> > >

> > >This is a general question to the group.

> > >When you had your biopsy did the doctors say they

>could tell from the

> > >biopsy

> > >that you have AIH? My GI doctor said no. But in

>my reading there is a

> > >different pattern of inlammation. Also, I know

>some of us have diagnosis

> > >of

> > >cirrhosis. If your biopsy says cirrhosis wouldn't

>it be more difficult to

> > >determine AIH? I see Dr. Czaja in August and am

>just curious about others

> > >biopsies.

> > >Thanks again

> > >Susie

> > >One more question can you have a positive ANA and

>not have AIH? or any

> > >autoimmune disease.

> > >

> > >---------------------------

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Guest guest

I go for laparoscopy biopsy on Thursday. Someone said I need to lie down on

ride home. I asked surgeon, he said no, not necessary! Do I need to stay

flat or not?????????

J

New Jersey

>From: KATBERCOO@...

>Reply- onelist

> onelist

>Subject: Re: [ ] biopsy with AIH

>Date: Thu, 15 Jul 1999 01:25:48 EDT

>MIME-Version: 1.0

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>

>From: KATBERCOO@...

>

>Dear :

>

>Good luck! You're in my prayers! Let us know how it goes!

>

>Take care!

>Kathy (AIH)

>Seattle area

>

>

>---------------------------

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Hi

I did this kind of biopsy one year ago. When you go back home it still hurts

in some positions but if you change it the pain go away. You only have to

look for the best way for you to lie down.

It's so difficult to fins the words in English ! I hope you got it. :o)

Don't worry abour that.

Take care

AIH

Brazil

-----Mensagem original-----

De: susan johnson <shireen42@...>

Para: onelist < onelist>

Data: Segunda-feira, 19 de Julho de 1999 02:37

Assunto: Re: [ ] biopsy with AIH

>From: " susan johnson " <shireen42@...>

>

>I go for laparoscopy biopsy on Thursday. Someone said I need to lie down

on

>ride home. I asked surgeon, he said no, not necessary! Do I need to stay

>flat or not?????????

>

> J

>New Jersey

>

>

>>From: KATBERCOO@...

>>Reply- onelist

>> onelist

>>Subject: Re: [ ] biopsy with AIH

>>Date: Thu, 15 Jul 1999 01:25:48 EDT

>>MIME-Version: 1.0

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>>Dear :

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>>Good luck! You're in my prayers! Let us know how it goes!

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>>Take care!

>>Kathy (AIH)

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Guest guest

Hi, with my biopsy they had me stay on my side for 4 hours in the hospital

before I could go home. That was to make sure it didn't start bleeding. It

gave me a big headache, for which they would not give me anything for, because

the doctor wasn't there, and no one had any painreliever. In a hospital no

less! Probably would have cost 20.00 a pill anyway! Lynn aih

Roselle50@... wrote:

> From: Roselle50@...

>

>

>

> When I had it I had to stay in the hospital outpatient on my back for two or

> more hours and then the sprung me.

>

> Sue AIH

> Wisconsin

>

> ---------------------------

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I wonder if prothrombin time at the time of biopsy has something to do with

how long you have to lie down after a biopsy? I had my liver biopsy in the

hospital so no problem about lying down - that's all I COULD do. I know

that they considered me high risk for bleeding and told my husband that

they had to collect 5 units of plasma before they did the biopsy. I've

been told by my doctors since then that a liver biopsy is a " risk "

procedure. I've also had a lung biopsy, just last year. They wanted to

keep me in the hospital overnight but I convinced them that I'd go to the

hotel and stay in bed so they let me go after a couple of hours bed rest

after the biopsy.

I'd be a little nervous about getting up and being active soon after a

liver biopsy - at least ask your doctor about the bleeding possibilities

after a laparoscopy. It might offend him, but it never hurts to bring

these things out.

Take care,

Geri

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