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Kellie,

not sure what the percentages are, but when I conceived, my TSH was 1.5 - I

don't know if that's helpful to you or not...

----Original Message Follows----

From: inksavvy@...

Reply-hypothyroidism

hypothyroidism

Subject: question

Date: Wed, 22 Oct 2003 07:30:36 EDT

What is the average conception percentage upon women with hypothyroid

disease? and what are some known complications during pregnancy?

thanks so much.

kellie

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It is helpful to me! Cause I wanna TTC soon and when my FT4 and FT3

are good, my TSH settles around 1.5. Then I read stuff that to

conceive the TSH has to be suppressed, and it worries me. Glad to

know that for you, and Shomon, between 1 and 2 worked. :)

Jan

> Kellie,

> not sure what the percentages are, but when I conceived, my TSH was

1.5 - I

> don't know if that's helpful to you or not...

>

>

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Kim

calm down this went along with poly jra the numbness was a problem and she was taken to the nuerologist to check for pinched nerves and carpal syndrome

she was put in wrist braces those didnt help her but excercises did

for some reason those joints used alot will have this happen in the hands

ask these questions what was she doing right before the rash and red started

more than likely she was useing her hands maybe even writing or gripping something

this will cause it everytime could pick up a can and put it down and her hand is red or theres a numb feeling somedays she does ok some are bad

another thing to watch for is cuts these get infected real easy

theres really nothing to stop this but to manage it with things

the parafin wax is good or heat up rice in the microwav let her play with it with her hands also get a soft squeeze ball to sqieeze when shes not useing her hands

and play doh is good you dont realize it but useing play doh is excercise to the hands the rashes come and go the red come and go

let the doctor know ALL of these symtoms this helps him

is 16 she still has these symtoms she manages them ok

if this happens ask the teacher for extra time to write or another option

in the 504 you can ask for this also

since melissas hands are affected the school gave her a computer its alot easier to use than gripping a pencil

another thing to help is get her the big pencils and pens

let me know if you need any more help

Robbin

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thanks wendy, i think you may have misunderstood - I do not wish to be hyper

that's why I'm questioning if going from .112 to .125 would do that....

----Original Message Follows----

From: " G. Santee " <wendysantee@...>

Reply-hypothyroidism

hypothyroidism

Subject: Re: question

Date: Mon, 8 Dec 2003 06:23:01 -0800 (PST)

_________________________________________________________________

Browse styles for all ages, from the latest looks to cozy weekend wear at

MSN Shopping. And check out the beauty products! http://shopping.msn.com

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I'm hoping that the increase would bring my TSH to around 1 or slightly

under. I guess I can't know for sure until I try. I feel like crap now and

my TSH is 2.5. thanks

----Original Message Follows----

From: " G. Santee " <wendysantee@...>

Reply-hypothyroidism

hypothyroidism

Subject: Re: question

Date: Mon, 8 Dec 2003 06:49:50 -0800 (PST)

Yes it would make you hyper if your body didn't need

that much hormone.

_________________________________________________________________

Don’t worry if your Inbox will max out while you are enjoying the holidays.

Get MSN Extra Storage! http://join.msn.com/?PAGE=features/es

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You could always give it a try, , if your doctor is willing. Like you said,

you won't know 'til you try! Hugs, Sheila

K a r e n P <karlynn17@...> wrote:I'm hoping that the increase would

bring my TSH to around 1 or slightly

under. I guess I can't know for sure until I try. I feel like crap now and

my TSH is 2.5. thanks

----Original Message Follows----

From: " G. Santee "

Reply-hypothyroidism

hypothyroidism

Subject: Re: question

Date: Mon, 8 Dec 2003 06:49:50 -0800 (PST)

Yes it would make you hyper if your body didn't need

that much hormone.

_________________________________________________________________

Don’t worry if your Inbox will max out while you are enjoying the holidays.

Get MSN Extra Storage! http://join.msn.com/?PAGE=features/es

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You won't know it until you try it, but my guess is: nope.

Jan

> If my TSH is 2.5 and I'm on .112 Synthroid, would going up to .125

push me

> toward hyper?? thanks for any imput :)

>

>

>

> _________________________________________________________________

> Winterize your home with tips from MSN House & Home.

> http://special.msn.com/home/warmhome.armx

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ahh yes i am taking vit b thanks for the clarification

========Original Message========

Subj: Re: question

Date: 12/15/2003 10:42:57 AM Eastern Standard Time

From: nicasdreamjester@...

Reply-to: candidiasis

candidiasis

Sent from the Internet (Details)

>

>

>And my urine is almost day glo Yellow

>

Are you taking Vit B by any chance? That will turn your urine neon

yellow. (They really oughta put a label on this stuff cause the first

time it happened to me I FREAKED!) I don't know about the smell, but

Vit B tablets have the nastiest smell so maybe that's what your smelling

in your bowel movements.

--

" My dog isn't stubborn, he's just smarter than me! " - maf

Marni Fowler, CPDT

Jester, NJC (finally got some letters!)

4, CGC

Gainesville, FL

APDT #5372P exp. 12/03

http://www.classactfordogs.com

BARF Shirts! => http://www.nicasdreams.freeservers.com

Ask me about health food for pets

http://www.raw4dogs.com

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>

>

>And my urine is almost day glo Yellow

>

Are you taking Vit B by any chance? That will turn your urine neon

yellow. (They really oughta put a label on this stuff cause the first

time it happened to me I FREAKED!) I don't know about the smell, but

Vit B tablets have the nastiest smell so maybe that's what your smelling

in your bowel movements.

--

" My dog isn't stubborn, he's just smarter than me! " - maf

Marni Fowler, CPDT

Jester, NJC (finally got some letters!)

4, CGC

Gainesville, FL

APDT #5372P exp. 12/03

http://www.classactfordogs.com

BARF Shirts! => http://www.nicasdreams.freeservers.com

Ask me about health food for pets

http://www.raw4dogs.com

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>

>

>ahh yes i am taking vit b thanks for the clarification

>

Creepy isn't it?

--

" My dog isn't stubborn, he's just smarter than me! " - maf

Marni Fowler, CPDT

Jester, NJC (finally got some letters!)

4, CGC

Gainesville, FL

APDT #5372P exp. 12/03

http://www.classactfordogs.com

BARF Shirts! => http://www.nicasdreams.freeservers.com

Ask me about health food for pets

http://www.raw4dogs.com

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I am certain that the Master Cleanse could help her. Also try, Dr.

Breuss' Cancer Cure, and Hulda . Ultimately a long fast, will

starve everything out including cancer.

Joyce

> hello ,

>

> well, this is the third message i try to post ,, i hope it will be

> posted, although i have nothing in mind why the others were not

> posted ??

>

> well i asked before if there is any alternative for maple

syrup,well

> i read the master cleanse book , and saw that there is an

> alternative which is sugare cane .. which for my surprise is found

> in my country .. although i am wondering how can i exctract the

> juice from it (since i was told that i can't do that in a juicer)??

>

> additional question ... my friends mother found out last week that

> she had cancer in her intestine , can the master cleanse be

applied

> in her situation ,, will it help her ???

>

> hope i'll get posted this time ,,

> and thanks alot for any replies in advance..

> :)

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That sound like high estrogen to me,.I suffer from estrogen dom.

and my stomach was huge.It seemed that was the only place I gained

weight.I just turned 34.I started with progesterone cream about 4 months

ago(thanks to Gracia!!:):)) and I have lost 90% of my stomach and I have

steadily been losing weight all over.

Deneen:):)

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that sounds just like me, so I would be very interested in the answer

too. I might add that I am almost 10 months without a period now so

probably estrogen dominant, I have been using progesterone cream for

over a year and have noticed very little difference.

Lynda (in the UK)

----- Original Message -----

From: " K a r e n P " <karlynn17@...>

> my sister (other than the one I've described before) has gained a

lot of

> weight in her abdomen (she looks 8 months pregnant), has intense

insomnia,

> and has high pulse (120ish). I finally convinced her to get her

adrenals

> checked and I was wondering if this screams out at anyone as

something

> specific. She is 33 years old. thanks guys :)

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When I took progesterone cream for a month it cause my uterine lining

to grow thus you look like you are gaining weight---we all have to be

very careful with these hormones---sometimes you need estrogen and

something you need progesterone---and if something is wrong and you

don't know what it is--get off whatever you are doing and go to the

doctor.

I was too young for progesterone cream and get this one---still don't

need it at 45--must make a lot of that hormone. I just can't take it.

it's really better off using pregnenolone and or dhea instead of

these creams---dhea and pregnenolone make these hormones that we need-

--and pregnenolone is safer to use.

http://www.vitacost.com/science/hn/Supp/Pregnenolone.htm

Pregnenolone

What it does

Where found

Are you deficient?

Amount to take

Side Effects & Interactions

References

What does it do?

((((Pregnenolone serves as a precursor to other hormones, including

dehydroepiandrosterone (DHEA) and progesterone.))))

The functions of pregnenolone in the body are not well known. It has

been suggested the role of pregnenolone in the body is to serve as

a " mother steroid " (precursor hormone). Aside from that role, it has

no known functions in the body.

Many effects of pregnenolone on the nervous system have been studied.

Rat studies indicate powerful memory-enhancing effects,2 far beyond

that of other neuroactive substances.3 4 In healthy men aged 20 to

30, administration of pregnenolone (1 mg daily) was found to improve

sleep quality and decrease intermittent wakefulness.5

It has been suggested this hormone may play a role in the

neuroendocrine response to stress. In a study of airplane pilots

subjected to stress, administration of pregnenolone (25 mg twice

daily) improved performance without causing adverse side effects.6 In

a study of the stress response in rats, an increase in anxiety was

observed following administration of pregnenolone. The researchers

suggested this was a beneficial response during a stressful period

and was initiated through the nervous system.7

In a study of rats subjected to spinal cord injury, administration of

pregnenolone in combination with the anti-inflammatory medication

indomethacin (Indocin®) and an immune-modulating substance (bacterial

lipopolysaccharide) promoted recovery of nerve function. The effect

was more pronounced with combination therapy than with any one of

these substances given singly or in combinations of two. Pregnenolone

has not been studied in humans with spinal cord injuries.8

Pregnenolone appears to exhibit an antagonistic effect on the calming

receptors in the brain (gamma-amino butyric acid [GABA] receptors),

resulting in an excitatory effect. It is possible this alteration in

nervous system transmission could contribute to seizure activity.9 10

Steroid hormones are known to affect mood and behavior via effects on

the nervous system. In people with either current depression or a

history of depression, pregnenolone in the cerebrospinal fluid (the

fluid that bathes the brain) was significantly lower, than levels in

healthy people. In addition, it was found that patients with active

depression had lower levels of pregnenolone compared with those with

a prior history of depression.11

In a double-blind study of elderly women with wrinkles, daily

application of a 0.5% pregnenolone acetate cream improved the visible

wrinkling of the skin. When the treatment was discontinued, the

benefit was not maintained. Because the results were only temporary,

it is suggested the beneficial effect of the cream was due to

improved hydration of the skin.12

Researchers have reported on the use of pregnenolone in a variety of

rheumatologic diseases. In a study of pregnenolone therapy

(intramuscular injection, 50–600 mg daily) for rheumatoid arthritis,

six of eleven people experienced moderate to marked improvement in

symptoms of joint pain and joint mobility. The symptom improvement

was apparent two to four days after therapy was initiated. In a study

of 13 adults with osteoarthritis, pregnenolone therapy reduced the

pain and improved the range of motion in seven of the study

participants. Pain recurred when therapy was discontinued. In a

person who suffered from gouty arthritis that was unresponsive to

conventional medications, pregnenolone therapy resulted in a dramatic

response within three days of initiating therapy. This patient

received 300 mg daily of pregnenolone (by intramuscular injection)

for four weeks, followed by 200 mg weekly of pregnenolone as a

maintenance amount. This study of pregnenolone therapy in

rheumatologic diseases also reports a substantial benefit in patients

with systemic lupus erythematosus (SLE), psoriasis, and scleroderma.

Of the 59 people reported in this paper, the only adverse effect was

redness or pain at the site of injection. No systemic adverse effects

were reported.13

Where is it found?

The cells of both the adrenal gland and the central nervous system

synthesize pregnenolone. Human studies show there are much higher

concentrations of pregnenolone in the nervous tissue, than in the

bloodstream.14 Animal studies indicate the concentration of

pregnenolone in the brain is ten-fold higher than that of other

stress-related hormones (including DHEA).15 Pregnenolone is present

in the blood as both free pregnenolone and a more stable form,

pregnenolone-sulfate.

Who is likely to be deficient?

Since it is not an essential nutrient, pregnenolone is not associated

with a deficiency state.

How much is usually taken?

Pregnenolone is generally available in amounts of 10 to 30 mg. It is

not known what an appropriate intake is for humans or whether the

benefits of taking this hormone outweigh the risks.

Are there any side effects or interactions?

Due to its antagonistic effects on the GABA receptor in the central

nervous system, supplementation with pregnenolone could cause

problems in people with a history of seizures. Pregnenolone

supplementation may increase the levels of progesterone and DHEA in

the body and possibly the levels of other hormones (testosterone and

estradiol). In theory, pregnenolone could cause disturbances in the

endocrine system, which may manifest as changes in the menstrual

cycle or the development or aggravation of hormone sensitive diseases

(including breast and prostate cancer). The side effects and

interactions with other therapies are currently unknown.

At the time of writing, there were no well-known drug interactions

with pregnenolone.

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my sister wrote a letter to her doctor saying what all her symptoms were and

asked for adrenal and thyroid testing. I told her to do it during her

period b/c that's when my endo is doing mine, but her doctor disregarded

that and did it anyway. i'm afraid that they will come back normal and he

won't test her again - we'll see though....

----Original Message Follows----

From: jezebel56@...

Reply-hypothyroidism

hypothyroidism

Subject: Re: question

Date: Tue, 13 Jan 2004 08:51:44 -0600 (CST)

That sound like high estrogen to me,.I suffer from estrogen dom.

and my stomach was huge.It seemed that was the only place I gained

weight.I just turned 34.I started with progesterone cream about 4 months

ago(thanks to Gracia!!:):)) and I have lost 90% of my stomach and I have

steadily been losing weight all over.

Deneen:):)

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Thanks for the answer. This can be rather scary and I have no one

that I feel like I can talk to. It just scares them and I have to

deal with that then. Don't get me wrong, my family is wonderful, but

they love me too much LOL.

I will probably be coming back this next week with more questions.

Thanks for being here for everyone.

<><TammieD><>

Good luck!

Claudine

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Hello Tammie,

You are very right, its rather scary. There's lots of folks

here that know stuff, and lots of folks that just have the

experience and care. Sorry you had to come looking. Talk

anytime.

Sally

shines@...

Re: question

Thanks for the answer. This can be rather scary and I have

no one

that I feel like I can talk to. It just scares them and I

have to

deal with that then. Don't get me wrong, my family is

wonderful, but

they love me too much LOL.

I will probably be coming back this next week with more

questions.

Thanks for being here for everyone.

<><TammieD><>

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Hi ,

I can't answer your question about the test.

Yes siblings can develop JRA also.It's not real common but can and does happen.

Hugs

Becki and 5 systemic

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,

I know many families with more than one child having jra. Our docs

say this is (at least in our country) a family-related disease, only

the mechanism is not known.

I myself have two children with jra in our family but they are not

biologically related (the other one a foster child).

Soili

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I don't think anyone needs these things, it is entirely

possible to lose weight without it, so long as you

are patient with yourself....

And there are warnings on the packaging for those

who have metabolic problems and psychological

disorders, so it must " speed " things up excessively.

Combine this with thyroid meds and I think you

have big trouble!

C.

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Hi Tammi....

You said you are a 1...are you talking about genotype or your liver. If you are

talking about your liver, you don't have much fibrosis. If you are talking about

your genotype, than that is completely different.

There is no difference in the pharmaceutical drugs that you will be

prescribed...you would take the same PegIntron or Pegasys as every one else.

Genotype 1's require a different length of treatment. Genotype 2's are usually

treated for 6 months....at 3 months they are tested for response and if they are

responding they do another 3 months of treatment.

Genotype 1's are a bit more difficult to clear the virus. Rule of thumb is that

you have your first RNA done at 6 months of treatment and if you are responding

you will do the full 48 weeks of treatment. But keep the hope....there are a lot

of genotype 1s here who have cleared the virus.

The choice between PegIntron (Schering Plough's treatment) and Pegasys (Roche's

treatment) is made probably by which ever pharma gives the better kickbacks to

the doctors. At County here in Chicago, they use Pegasys (Roche) with Ribavarinn

(Schering)...that is because they got the better price on Pegasys from Roche and

the better price on Ribavarinn from Schering. Roche's version of ribavarinn is

Copegys.

So there is really no difference in what drug you take, just which manufacturer.

There have been varying studies done as to the efficacy of the two...and Roche

is getting ready to do clinical trials on people who responded to PegIntron and

then relasped...they want to prove they have the better pegylated interferon.

Whether or not they do, I don't know. I don't know of any studies proving that

more people who did Pegasys sustained their response. That is the type of info

you need to ask Claudine or Doc. I stopped following studies some time ago.

Good luck and remember we are all here for you when you need us.

Blessings

Tatezi

question

I got the test results back from the biopsy and I am a 1. They are

talking about starting the treatments as soon as I am released by the

rheumatologist.

My question is...what are the 2 different meds for...layman's terms

please. Everyone is asking me questions about the treatments and I

really don't know how to respond. All I know is that it makes the hep

go away or it doesn't. Not much to go on there :)

Any help is appreciated.

Thanks.

<><TammieD><>

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Hi Tammi....

You said you are a 1...are you talking about genotype or your liver. If you are

talking about your liver, you don't have much fibrosis. If you are talking about

your genotype, than that is completely different.

There is no difference in the pharmaceutical drugs that you will be

prescribed...you would take the same PegIntron or Pegasys as every one else.

Genotype 1's require a different length of treatment. Genotype 2's are usually

treated for 6 months....at 3 months they are tested for response and if they are

responding they do another 3 months of treatment.

Genotype 1's are a bit more difficult to clear the virus. Rule of thumb is that

you have your first RNA done at 6 months of treatment and if you are responding

you will do the full 48 weeks of treatment. But keep the hope....there are a lot

of genotype 1s here who have cleared the virus.

The choice between PegIntron (Schering Plough's treatment) and Pegasys (Roche's

treatment) is made probably by which ever pharma gives the better kickbacks to

the doctors. At County here in Chicago, they use Pegasys (Roche) with Ribavarinn

(Schering)...that is because they got the better price on Pegasys from Roche and

the better price on Ribavarinn from Schering. Roche's version of ribavarinn is

Copegys.

So there is really no difference in what drug you take, just which manufacturer.

There have been varying studies done as to the efficacy of the two...and Roche

is getting ready to do clinical trials on people who responded to PegIntron and

then relasped...they want to prove they have the better pegylated interferon.

Whether or not they do, I don't know. I don't know of any studies proving that

more people who did Pegasys sustained their response. That is the type of info

you need to ask Claudine or Doc. I stopped following studies some time ago.

Good luck and remember we are all here for you when you need us.

Blessings

Tatezi

question

I got the test results back from the biopsy and I am a 1. They are

talking about starting the treatments as soon as I am released by the

rheumatologist.

My question is...what are the 2 different meds for...layman's terms

please. Everyone is asking me questions about the treatments and I

really don't know how to respond. All I know is that it makes the hep

go away or it doesn't. Not much to go on there :)

Any help is appreciated.

Thanks.

<><TammieD><>

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I don't know about an actual head-to-head study but I do know that Pegasys is

getting ready to start treating relapsed responders and non responder to

PegInron....I know this because that's what they want me to help promote.

Tatezi

I did read that there is going to be an actual head-to-head study

between Pegasys and Peg-Intron, but as far as I know it hasn't

started yet. Assuming it starts very soon, I'm figuring we ought to

know the results in about 4 years or so!

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I don't know about an actual head-to-head study but I do know that Pegasys is

getting ready to start treating relapsed responders and non responder to

PegInron....I know this because that's what they want me to help promote.

Tatezi

I did read that there is going to be an actual head-to-head study

between Pegasys and Peg-Intron, but as far as I know it hasn't

started yet. Assuming it starts very soon, I'm figuring we ought to

know the results in about 4 years or so!

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