Re: don't know how to interpret my test results from IGeneX

[Guest guest]

Igg 41 - the flagella tail for borrelia bacteria in general both 58 and 66 -

heat shock proteins specific to Lyme

The following is from my free lyme rersource cd...

0000000000000000000000000000000000000000000000000000000

Band 41 is nonspecific. It's from the flagella, or whip-like structure

common to spirochetes.

However 31 is ospA, outer surface protein A, which is so specific for

Lyme it was used for vaccine development - which is why it is NOT on the

CDC list of bands they count for positive. The logic was they thought

all the vaccinated people would be ospA positive, so they didn't want to

use it because it would look like everyone had Lyme disease. However, if

you have not been vaccinated with the Lyme vaccine, it is highly

significant. (Of course now the Lyme vaccine has been withdrawn from the

market anyway.) No other bacteria would cause you to have antibodies

against that protein. And 34 is ospB, outer surface protein B, another

vaccine candidate and also highly significant. 23-25 represents outer

surface protein C. With all those three you couldn't have a more

positive or specific blot!

Any doctor who understands this will consider your test positive.

Unfortunately many doctors discount A and B because they are not part of

the CDC surveillance criteria and many labs don't even bother reporting

them. However your blot is positive even without ospA and B.

> [ ] don't know how to interpret my test

> results from IGeneX

>

> I joined this group several month ago because I have been

> dealing with classic lyme symptoms, but really didn't have

> any knowlegde about lyme disease. Now that I received my test

> results I don't know if to continue to pursue the possibility

> of having Lyme disease. These are my results: I am only

> positive for IgM for 31 and 41 and

> IgG for 41 and 45

>

> My Family doctor had ordered a Western Blot with a regular

> lab and it showed two bands postive (I don't recall which

> ones), so my M.D. sent me to have blood work with IGeneX, but

> she admitted she doesn't know how to interpret the results

> and sent me to another Dr in town (but I don't want to see

> this other doctor because I heared not so good things about

> her. People told me she is extremely expensive and not very caring).

>

> Does anyone have an opinion on my test results ? I would

> really appreciate it.

> Also, I would like to find a LLMD in Colorado preferrably or

> willing to travel (especially New Mexico or Arizona- but

> really anyplace.)

>

> Thank you! Blessings!

> Regina

>

>

>

> ------------------------------------

>

> For free up to date information about Lyme disease and the

> known co-infections delivered to your email address see:

> Robynns_Lyme_List/

>

[Guest guest]

If your own family doctor is willing to treat with the suggested antibiotic

treatments - give it a try. Even negative results from IGeneX doesn't mean

you " don't " have lyme disease. From everything I've been told from my llmd,

about 50% of people who DO have lyme, test negative for it. Because of the

expense of IGeneX tests and his knowledge that my insurance wouldn't pay for

those tests, my llmd put me on a 4 month trial of antibiotics. He said if

at the end of 4 months - you've started to improve - that's the proof that I

have lyme. If I don't improve, then I've probably got something else. If

your doctor is willing to do this - give it a try. If your doctor wants

more info, either print her out some info from the web... or give me a call

and I'll see if my llmd is willing to talk with your doc.

Kathy

On Fri, Oct 16, 2009 at 7:06 PM, Regina <reginita777@...> wrote:

>

>

> I joined this group several month ago because I have been dealing with

> classic lyme symptoms, but really didn't have any knowlegde about lyme

> disease. Now that I received my test results I don't know if to continue to

> pursue the possibility of having Lyme disease. These are my results: I am

> only positive for

> IgM for 31 and 41 and

> IgG for 41 and 45

>

> My Family doctor had ordered a Western Blot with a regular lab and it

> showed two bands postive (I don't recall which ones), so my M.D. sent me to

> have blood work with IGeneX, but she admitted she doesn't know how to

> interpret the results and sent me to another Dr in town (but I don't want to

> see this other doctor because I heared not so good things about her. People

> told me she is extremely expensive and not very caring).

>

> Does anyone have an opinion on my test results ? I would really appreciate

> it.

> Also, I would like to find a LLMD in Colorado preferrably or willing to

> travel (especially New Mexico or Arizona- but really anyplace.)

>

> Thank you! Blessings!

> Regina

>

>

>

[Guest guest]

Regina,

Your labs are not definite for or against Lyme. You are in the gray zone.

On your IgG, band 41 is for flagella from Lyme or other bacteria. Band 45

is not specific for Lyme either. Band 41 is the most common Lyme band, but

by itself with no other Lyme specific bands you can not tell if it is due to

Lyme or not.

On your IgG, band 31 by itself or with band 41 may be due to Lyme or due to

various viral infections such as EBV. Your doctor needs to order the 31

epitope test to differentiate whether this positive band 31 result is due to

Lyme or another infection. The test is $100 from IgeneX. Your doctor just

has to call and then fax an order to Igenex for them to run the test on your

blood already in their lab. If this band 31 epitope test is positive for

Lyme, then you will have two positive bands and a positive Lyme test.

Diagnosis is dependent on your clinical symptoms. The lab tests are just

helpful in supporting a Lyme diagnosis. You can still have Lyme even if all

bands are negative.

Take care,

On Fri, Oct 16, 2009 at 10:06 PM, Regina <reginita777@...> wrote:

>

>

> I joined this group several month ago because I have been dealing with

> classic lyme symptoms, but really didn't have any knowlegde about lyme

> disease. Now that I received my test results I don't know if to continue to

> pursue the possibility of having Lyme disease. These are my results: I am

> only positive for

> IgM for 31 and 41 and

> IgG for 41 and 45

>

> My Family doctor had ordered a Western Blot with a regular lab and it

> showed two bands postive (I don't recall which ones), so my M.D. sent me to

> have blood work with IGeneX, but she admitted she doesn't know how to

> interpret the results and sent me to another Dr in town (but I don't want to

> see this other doctor because I heared not so good things about her. People

> told me she is extremely expensive and not very caring).

>

> Does anyone have an opinion on my test results ? I would really appreciate

> it.

> Also, I would like to find a LLMD in Colorado preferrably or willing to

> travel (especially New Mexico or Arizona- but really anyplace.)

>

> Thank you! Blessings!

> Regina

>

>

>

--

L. Richey, MD, ND

The Healthy Path, LLC

http://www.the-healthy-path.org

http://www.autism-in-the-christian-home.com

Sweet Creations Alpaca Farm, LLC

http://www.sweet-creations-alpaca-farm.org

http://www.alpacastreet.com/sweetcreationsalpacas.asp

[Guest guest]

I don't understand. My son, 5 years old, finally came back. Dr mailed it to

me.

IgeneX

IGG 18 +

41+

58+

IGM

41+

What is the significance of 41? Is there anything else that could cause that to

be positive? What are the chances that these positives are false vs. the

possibility that other bands are a false negative?

>

>

> Igg 41 - the flagella tail for borrelia bacteria in general both 58 and 66 -

> heat shock proteins specific to Lyme

>

> The following is from my free lyme rersource cd...

>

> 0000000000000000000000000000000000000000000000000000000

>

> Band 41 is nonspecific. It's from the flagella, or whip-like structure

> common to spirochetes.

>

> However 31 is ospA, outer surface protein A, which is so specific for

> Lyme it was used for vaccine development - which is why it is NOT on the

> CDC list of bands they count for positive. The logic was they thought

> all the vaccinated people would be ospA positive, so they didn't want to

> use it because it would look like everyone had Lyme disease. However, if

> you have not been vaccinated with the Lyme vaccine, it is highly

> significant. (Of course now the Lyme vaccine has been withdrawn from the

> market anyway.) No other bacteria would cause you to have antibodies

> against that protein. And 34 is ospB, outer surface protein B, another

> vaccine candidate and also highly significant. 23-25 represents outer

> surface protein C. With all those three you couldn't have a more

> positive or specific blot!

>

> Any doctor who understands this will consider your test positive.

> Unfortunately many doctors discount A and B because they are not part of

> the CDC surveillance criteria and many labs don't even bother reporting

> them. However your blot is positive even without ospA and B.

>

> > [ ] don't know how to interpret my test

> > results from IGeneX

> >

> > I joined this group several month ago because I have been

> > dealing with classic lyme symptoms, but really didn't have

> > any knowlegde about lyme disease. Now that I received my test

> > results I don't know if to continue to pursue the possibility

> > of having Lyme disease. These are my results: I am only

> > positive for IgM for 31 and 41 and

> > IgG for 41 and 45

> >

> > My Family doctor had ordered a Western Blot with a regular

> > lab and it showed two bands postive (I don't recall which

> > ones), so my M.D. sent me to have blood work with IGeneX, but

> > she admitted she doesn't know how to interpret the results

> > and sent me to another Dr in town (but I don't want to see

> > this other doctor because I heared not so good things about

> > her. People told me she is extremely expensive and not very caring).

> >

> > Does anyone have an opinion on my test results ? I would

> > really appreciate it.

> > Also, I would like to find a LLMD in Colorado preferrably or

> > willing to travel (especially New Mexico or Arizona- but

> > really anyplace.)

> >

> > Thank you! Blessings!

> > Regina

> >

> >

> >

> > ------------------------------------

> >

> > For free up to date information about Lyme disease and the

> > known co-infections delivered to your email address see:

> > Robynns_Lyme_List/

> >

[Guest guest]

Jgray1025,

Band 41 is representative of Lyme flagella plus flagella from other

bacteria.

You can have Lyme disease even if al bands are negative.

Diagnosis of Lyme disease is based on clinical symptoms - not on lab tests.

I suggest that you see an LLMD as soon as possible.

Good luck!

On Sun, Oct 18, 2009 at 11:56 PM, jgray1025 <jgray1025@...> wrote:

>

>

> I don't understand. My son, 5 years old, finally came back. Dr mailed it to

> me.

> IgeneX

> IGG 18 +

> 41+

> 58+

> IGM

> 41+

>

> What is the significance of 41? Is there anything else that could cause

> that to be positive? What are the chances that these positives are false vs.

> the possibility that other bands are a false negative?

>

>

[Guest guest]

41 is the tail (flagella) of a spirochete type organism. 18 is thought to be

very specific to Lyme.

http://tinyurl.com/yhy85xo

http://www.lymedisease.org/lyme101/lyme_disease/lyme_western_blot.html

or

http://tinyurl.com/yf5q8t4

http://www.lymedisease.org/lyme101/lyme_disease/lyme_disease.html

> [ ] Re: don't know how to interpret my test

> results from IGeneX

>

> I don't understand. My son, 5 years old, finally came back.

> Dr mailed it to me.

> IgeneX

> IGG 18 +

> 41+

> 58+

> IGM

> 41+

>

> What is the significance of 41? Is there anything else that

> could cause that to be positive? What are the chances that

> these positives are false vs. the possibility that other

> bands are a false negative?

>

[Guest guest]

,

Thanks.

If Band 41 could represent lyme or other bacteria, how can I find out what the

possible " other bacteria " it could possibly be? Where can I locate that

information? I need more proof for my husband to agree treatment with llmd

pediatriac dr. We will have to travel a long distance and pay a lot of money

out of pocket.

Thanks,

J

>

> >

> >

> > I don't understand. My son, 5 years old, finally came back. Dr mailed it to

> > me.

> > IgeneX

> > IGG 18 +

> > 41+

> > 58+

> > IGM

> > 41+

> >

> > What is the significance of 41? Is there anything else that could cause

> > that to be positive? What are the chances that these positives are false vs.

> > the possibility that other bands are a false negative?

> >

> >

>

[Guest guest]

It's specific to spirochetes -- it's the protein from the flagellum

that only spiros have. So if that pops up, you're looking at either

Lyme, yaws, or syphilis, which are the only spirochete diseases known

in humans. Lyme is, of course, far and away the most common of these

in the US.

Any one of those is serious enough to warrant further exploration.

Sara

On Oct 19, 2009, at 6:19 PM, jgray1025 wrote:

> ,

> Thanks.

> If Band 41 could represent lyme or other bacteria, how can I find

> out what the possible " other bacteria " it could possibly be? Where

> can I locate that information? I need more proof for my husband to

> agree treatment with llmd pediatriac dr. We will have to travel a

> long distance and pay a lot of money out of pocket.

>

> Thanks,

> J

>