Guest guest Posted December 4, 2010 Report Share Posted December 4, 2010 I cannot sleep. Nothing. The night seems endless. I read that some people here say you can take it in the morning. Others claim you must take it at night. Can I take it in the morning? Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 4, 2010 Report Share Posted December 4, 2010 LDN-day/night dosing controversy/research http://tinyurl.com/lgux5k -- Mechanisms involved in beneficial effect of LDN http://tinyurl.com/me85wb -- Changing time zones and LDN timing ??? http://preview.tinyurl.com/ohso7o -- Why I do Bihari dosing protocol over Zagon/Gilhooly http://tinyurl.com/l37lkk -- Taking LDN AM instead of PM ??????? http://tinyurl.com/yz4ajs8 -- LDN Taken Morning or Night? http://tinyurl.com/yho6g3l -- Why take LDN only once a day? http://ldn.proboards.com/index.cgi?board=forum & action=display & thread=1140 The LDN should only be given once per day and never be given before 9pm when we're off Daylight saving time(fall and winter) and never give LDN before 10pm during daylight saving time(spring and summer). This will ensure that the LDN is in the system during peak endorphin production time of between 2am and 4am(the most endorphins are produced during this time and it is very important to take advantage of this to stop disease progression). Never give LDN twice within 24 hours. Read the LDN website and read the Further Q and A page while there, it's an important page and understanding how LDN works and why we take LDN in this manner is vital. LDN should not be given any later than 3am. -- In regard to daytime dosing, of all the clinical trials of LDN conducted with humans, only one used daytime dosing--a German study with a group of MS patients. While about a third of the group did experience limited benefit, this is the comment made about the trial by Dr. Gluck, webmaster of http://ldninfo.org: Unfortunately, because of some early complaints of sleep disturbance, the principal investigator of this trial switched all of the study group to taking LDN at 9 am in the morning, a questionable dosage time. It is generally recognized that the most effective time to take LDN is at bedtime, between 9 pm and 3 am, due to the fact that the endorphins for each day are always produced at their peak rate in the pre-dawn hours. A 9 am dosage time, as was used in this trial, might conceivably suppress—rather than boost—a patient's immune system. Low Dose Naltrexone (LDN): The German MS Study http://www.webspawner.com/users/germanldnstudy/index.html -- > > I cannot sleep. Nothing. The night seems endless. > I read that some people here say you can take it in the morning. Others claim you must take it at night. > Can I take it in the morning? > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted December 5, 2010 Report Share Posted December 5, 2010 Hi ,Wow! I was surprised that you are having such a response when taking just 0.2mg. How are you delivering such a small dose? Do you have capsules made up to that amount or are you dissolving a 50mg tablet in 50ml of water and using a dropper? Or some other way???? Is it possible that you not really taking 0.2mg and may by some mistake taking a higher dose? (I'm not saying you are, but just analyzing the possibilities.)Before taking LDN, were you having any sleep problems at all? I know that when I started LDN about seven weeks ago, I had done a lot of research for over a month before I started taking it. By the time I started, I was very anxious about falling victim to sleepless nights, as I know how terrible they can be. The first night I took LDN I woke about 3 am and was awake for about 30 minutes with my mind going around in circles worried that I wasn't going to be able to get back to sleep because I'm taking LDN. Next thing I knew it was morning and the sun was shining. The same thing happened the following night, but then that was all. I realized that my waking periods were 90% to do with my anxiety over being awake than the effect of the LDN itself. I only started on 1.5mg too. I don't know if others have experienced the same thing, but it's worth considering.Ron Ball in another reply to your post has shared his experience of suffering the same symptoms due to a Babesia bacterial infection. Babesia is a common co-infection with people suffering with Lyme disease. Lyme disease manifests itself in many ways including CFS. Have you been tested for Lyme? Again, I'm not saying that this is your issue, but I just like looking under every stone. You just never know that the answer your looking for may be under the next stone.The only other thought I have is heavy metal toxicity. Not only can it cause CFS (and a host of other chronic conditions), but it can also play havoc with sleep patterns. EG. Do you have any amalgam (silver) fillings? If so, you may have mercury toxicity. A distant friend of mine suffered from CFS for around ten years before having her dozen (?) fillings removed. She was free from CFS within a few months.I realize that my suggestions are not LDN specific (except the first one), but as you have had a reaction to such a small dose, then it indicates to me that there is something lurking just below the surface that needs to be dealt with.-n.PS: If this post reply appears twice, I apologize as it didn't seem to get "sent" the first time.From: Dresen <wendy.dresen@...>Subject: [low dose naltrexone] just started ldn and already need advice low dose naltrexone Received: Saturday, 4 December, 2010, 2:18 PM I cannot sleep. Nothing. The night seems endless. I read that some people here say you can take it in the morning. Others claim you must take it at night. Can I take it in the morning? Quote Link to comment Share on other sites More sharing options...
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