Re: LDN and polymyalgia rheumatica

[Guest guest]

I really hate to get involved with this question, and the he said,he said responses. Who is right, Zagon or Bihari, well they both are right. One has to look at the diurnal nature of endorphin secretion to understand HOW they are both right. You get your zenith peak during your normal sleep cycle. You get your penultimate peak during your wake cycle. Taking LDN prior to your zenith peak will give you more bang for you buck than prior to your wake cycle peak. Therefore you will get some increase taking LDN at times other than prior to bedtime but they will not be the most you can get. Now if you take it indiscriminately temporally, then depending of which peak is next in the cycle, you will get a fraction of the response.you would get if taken at an appropriate time frame. This explains why both docs are right, for those taking it in the am, you get the PM peak to skew upwards, those taking the PM dose gets the am peak to skew upwards.

Dr.Skip

[Guest guest]

Dr Skip! Thank you so much for this, it makes so much sense. I'm so glad

to have this understanding.

--

>I really hate to get involved with this question, and the he said,he said

>responses. Who is right, Zagon or Bihari, well they both are right. One

>has to look at the diurnal nature of endorphin secretion to understand HOW

>they are both right. You get your zenith peak during your normal sleep

>cycle. You get your penultimate peak during your wake cycle. Taking LDN

>prior to your zenith peak will give you more bang for you buck than prior

>to your wake cycle peak. Therefore you will get some increase taking LDN

>at times other than prior to bedtime but they will not be the most you can

>get. Now if you take it indiscriminately temporally, then depending of

>which peak is next in the cycle, you will get a fraction of the

>response.you would get if taken at an appropriate time frame. This

>explains why both docs are right, for those taking it in the am, you get

>the PM peak to skew upwards, those taking the PM dose gets the am peak to

>skew upwards.

>Dr.Skip

>

>

>

~~~ There is no way to peace; peace is the way ~~~~

--A.J. Muste