Guest guest Posted June 15, 2010 Report Share Posted June 15, 2010 To put this matter to rest, I contacted Dr Zagon for his views on dosing 4.5mg x 2/day and the below is his response:- Dear Jayne: First, LDN is an immunosuppressant - not an immunostimulant (as thought - wrongly - by many). Second, we recommended a dosage of 3 - 10 mg/day based on pharmacokinetics. 9 mg/day - getting to the edge but should be okay - this person may not be optimizing her dosage however. Remember - you only want the LDN working for 4-6 hr/day - the higher the dosage the longer it hangs around and the shorter the time for your endorphins to work. Third, stress has nothing to do with LDN. Fourth, I am seeing some people who become tolerant to LDN and need to take it once every 2 and some every 3 days. I can tell you that LDN can work even as long as once every 4 or 5 days. Dr. Zagon Jayne Crocker Chairperson www.LDNNow.com Important! Please sign our LDN petition to the European Parliament by clicking here tel: +44 (0) 7877 492 669 Dr Steele MBE, talking about LDN LDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. .. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 15, 2010 Report Share Posted June 15, 2010 With regards to the below, you may find this link also of interest with regards to what Dr Zagon is saying http://www.4um.com/tutorial/science/pharmak.htm Jayne Crocker Chairperson www.LDNNow.com Important! Please sign our LDN petition to the European Parliament by clicking here tel: +44 (0) 7877 492 669 Dr Steele MBE, talking about LDN LDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. .. From: jaynelcrocker [mailto:jaynelcrocker@...] Sent: 15 June 2010 16:22 'LDNforFibro '; 'Any_Other_Dose_LDN '; 'low dose naltrexone ' Subject: Dosing Twice a Day - From Dr Ian Zagon To put this matter to rest, I contacted Dr Zagon for his views on dosing 4.5mg x 2/day and the below is his response:- Dear Jayne: First, LDN is an immunosuppressant - not an immunostimulant (as thought - wrongly - by many). Second, we recommended a dosage of 3 - 10 mg/day based on pharmacokinetics. 9 mg/day - getting to the edge but should be okay - this person may not be optimizing her dosage however. Remember - you only want the LDN working for 4-6 hr/day - the higher the dosage the longer it hangs around and the shorter the time for your endorphins to work. Third, stress has nothing to do with LDN. Fourth, I am seeing some people who become tolerant to LDN and need to take it once every 2 and some every 3 days. I can tell you that LDN can work even as long as once every 4 or 5 days. Dr. Zagon Jayne Crocker Chairperson www.LDNNow.com Important! Please sign our LDN petition to the European Parliament by clicking here tel: +44 (0) 7877 492 669 Dr Steele MBE, talking about LDN LDNNow are a political/pressure group of individuals dedicated to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled for the myriad of uses it shows benefit for. .. Quote Link to comment Share on other sites More sharing options...
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