RE: Glass Ceilling of 2.5mls?

[Guest guest]

Fiona -

I cannot speak much to the doage issue. I was able to start right at

4.5 mg and have tolerated it exceedingly well.

The physical symptoms in your leg sound like neuropathic/referral pain

to me - tracking up to the low back - L4-5 or L5-S1 areas - do you

have any herniated/ruptured discs in the area? Any hx of trauma to

the back (and/or car accident)?

I have herniated and ruptured discs in that area and have similar

symptoms - left leg/ankle/foot. I have had better pain management

with the LDN and the DLPA than I did with years of epidurals,

surgeries, ibuprofen, vidodin, percocet, etc - but I still have

symptoms. That left calf especially can get so tight I can barely

walk sometimes.

Just throwing it out there because sometimes we link everything to one

thing (for you it might be ME/CFS - for me it is UC and the car

accident) but fail to realize the culprit might be something else

entirely.

Peace,

Jaxi

On Thu, Jun 3, 2010 at 9:01 AM, Fiona <f.hodgkiss@...> wrote:

> I take LDN for ME/CFS. I take pharmacy made liquid LDN at night.

>

> I have had to take my time building up the dose and the doctor commented that

perhaps I am a little more sensitive than some.

>

> I had major palpitations and I felt hot and flushed when I had 2.75mls. I had

to ride it out and I didn't get to sleep until 2am.

>

> I have used my common-sense and reduced back to 2.5mls because the

palpitations were worrying and I didn't want to repeat it.

>

> Clearly I am fine withthe 2.5mls and I am wondering if this is it now and if

it's doing it's job and if this is as much as I can tolerate? Has anybody else

found this?

>

> I have had some improvements in my muscle function, where most muscles feel

less solid and I get fewer vibrating sensations in my muscles. However a

sticking point, is my calves, kust above the tendon, where the leg widens, this

area can feel tight and uncomfortable. In addition, I also get discomfort in the

muscles under my feet.

>

> Following yoga yesterday, I have had a lot of solidness in my lower legs and

feet and a vibrating sensation in my left lower leg and foot again. Such

symptoms are due to moderate exertion.

>

> I was just wondering if anybody else is in a similar situation?

>

> Fiona

>

>

>

>

> ------------------------------------

>

>

[Guest guest]

Hi Fiona

I had this when I first increased dose, exactly the same, going

from 2.5 to 2.75ml. I went back to 2.5 and stayed there a couple of weeks, then

tried again, but going up even tinier (non exact) amounts. I eventually got to

4.5ml which is where I’m at now. It took several months though. Join the VeryLowDose

group for more advice...

Rory

From: low dose naltrexone

[mailto:low dose naltrexone ] On Behalf Of Fiona

Sent: 03 June 2010 15:01

I had major palpitations and I felt hot and flushed when I had 2.75mls. I had

to ride it out and I didn't get to sleep until 2am.

I have used my common-sense and reduced back to 2.5mls because the palpitations

were worrying and I didn't want to repeat it.