[Any_Other_Dose_LDN] Re: Dosing Twice a Day - From Dr Ian Zagon

[Guest guest]

With regards to

> I think he means that during

the several hours that naltrexone is blocking receptors, it is suppressing the

immune system. But not once it comes out, and the receptors are no longer

blocked.

>

So in that way, I assume LDN is

a so called temporary immune-suppressant then. Hypothetically if you were to

take LDN 4 or 6 times a day (which you wouldn't do anyway) then I guess you

would call it an immune suppressant for sure. So from what you are saying, it

only suppresses the immune system for a while, during the receptor blocking.

Therefore once the endorphins are released, the immune system is no longer

suppressed, so it's temporary i.e. 4 out of 24 hours (approx) suppression,

rather than 24 out of 24 hours...

This is something else Dr Zagon has said:-

LDN works through what is called the opioid growth

factor

>- a native peptide (and its receptor) in your body.

LDN is a decoy

>that fills in at the site of the receptor - the body

not having the

>peptide makes more of it in compensation. Now

the trick we discovered

>30 years ago. A short time of naltrexone - low

dose naltrexone is the

>term lay people use (but really intermittent

opioid receptor blockade)

>increases the peptide. After the naltrexone is

metabolized - optimal

>time is 4-6 hours for around 3 mg, the high

levels of peptide and

>actually an increase in receptors as well can

interact. This depresses

>cell/viral proliferation - and makes you

better. By increasing your dose of LDN you are cutting into the

>time you need for an optimal reaction. Hence -

you feel problems.

>

My advice - take 3 mg/day. If you have a problem, start

>taking LDN once every 2 days (many folks are taking

it that way - and

>some every 3 days).

>

Dr. Zagon

>

A story. A lady calls me and says she has breast

>cancer. She is taking LDN and the cancer is growing

more rapidly. I

>ask her how LDN is being given - she says that since

LDN is so good,

>she is taking it several times a day. Now you know

why she had a

>faster growing cancer - she was not allowing

the opioid-receptor

>interaction to occur because of so much naltrexone.

>

And, if you block the receptors all day with naltrexone

>(high dose of naltrexone), we now see that wound

healing is

>accelerated. Why, because the cells are speeding up

in replication and

>healing the wound faster.

Therefore it is my opinion that Dr Zagon does not support the

twice daily dosing (which by the way was my original question to Dr Zagon) but does

support larger doses up to 10mg/day but for a short period of time. It is

also my opinion he believes in taking a minimum of 3mg to gain any benefit from

LDN and for some take this for up to every 5 days at a time as opposed to 0.5mg

every night – again, just my opinion.

I think the confusion with LDN comes from the point that

naltrexone does stimulate the immune system but when you do it for 4-6 hours,

the endorphins quickly pull it down again so you can ignore it, except that

this is how the OGF restores the normal zeroed immune system waiting to be

activated by a disease.

Now in the past we have come up with terms of an ‘out of

whack’ or ‘misbehaved’ immune system, in other words it is a chronically

active immune system that causes these diseases because they lose endorphin

production and cannot return to zero ie homeostasis. All autoimmunity is

found with low OGF and chronic immune activity and sickness behaviour.

Our immune systems become tired so when a real pathogen comes along we have a

poor response to it and have very low suppressor T cell population.

Restoration of the 100% immune response can be thought of as boosting the

immune system.

Jayne Crocker

Chairperson

www.LDNNow.com

Important! Please sign our LDN petition to the

European Parliament by clicking here

tel: +44 (0) 7877 492 669

Dr Steele MBE, talking about LDN

LDNNow are a political/pressure group of individuals dedicated

to getting Low Dose Naltrexone (LDN) accepted into modern medicine and trialled

for the myriad of uses it shows benefit for.

..

[Guest guest]

>

> > And, if you block the receptors all day with naltrexone

>

> >(high dose of naltrexone), we now see that wound healing is

>

> >accelerated. Why, because the cells are speeding up in replication and

>

> >healing the wound faster.

Hi Jayne and all

I know people have mentioned before that their hair and fingernails are growing

faster on LDN. This is definitely my experience. What are the implications of

that in terms of your above quote?

Could it mean the dose I am taking (4.5mg) is too high for me and is blocking

the receptors for too long? Or is the process of wound healing very different

from hair and fingernail growth?

Any comments?

Joan

[Guest guest]

Joan,What is your height and weight?JackieFrom: joan.spargo <joan.spargo@...>Subject: [low dose naltrexone] [Any_Other_Dose_LDN] Re: Dosing Twice a Day - From Dr Ian Zagonlow dose naltrexone Date: Thursday, June 17, 2010, 5:44 PM> > > And, if you block the receptors all day with naltrexone > > >(high dose of naltrexone), we now see that wound healing is > > >accelerated. Why, because the cells are speeding up in

replication and > > >healing the wound faster.Hi Jayne and allI know people have mentioned before that their hair and fingernails are growing faster on LDN. This is definitely my experience. What are the implications of that in terms of your above quote? Could it mean the dose I am taking (4.5mg) is too high for me and is blocking the receptors for too long? Or is the process of wound healing very different from hair and fingernail growth?Any comments?Joan------------------------------------