Re: Walking Pill

[Guest guest]

Ampyra (Fampridine-SR) is a sustained-release tablet formulation of the drug fampridine (4-aminopyridine, or 4-AP) Here is additional info: http://www.msrc.co.uk/index.cfm?fuseaction=show & pageid=1310On Jun 14, 2010, at 8:30 PM, P wrote: What is the drug/prescription name for the walking pill?I have heard of 4ap, which some have claimed has helped with walking ability.

[Guest guest]

,This is a a reply to someone else's

inquiry I sent regarding the "new" drug Ampyra. Ampyra is not actually

a new drug. It is 4-AP that has been patented by a pharmaceutical

company and is a slow release formulation. 4-AP is the fast release

formulation that I have been taking and still must be prescribed by a doctor.Ampyra (or Fampridine) is the patented drug already known as 4-Aminopyridine (4-AP), which has been available for years. 4-AP

is not a patentable medication, since it was discovered many years

before its effects on MS were known. Many doctors were aware of its

existence, but were not aware that it was available. The medication is

available as the raw ingredient, your doctor can prescribe it, and a

compounding pharmacy can put it into capsules.4-AP is a potassium channel blocker which can block the flow of potassium ions in nerve cells, which results in a more effective nerve impulse traveling down toward the muscles. As you probably know, the poor nerve impulses in patients with MS is the cause of most of the symptoms of the disease. The improved nerve conduction provided by 4-AP means that the muscles have a "louder signal" to tell them when to work and the stronger muscle contractions improve strength and fatigue in many patients. I

have been taking 30mg - 45mg of 4-AP daily (15mg at 4 hour intervals)

and have suffered no ill side effects. As I said in an earlier post,

my mobility has not improved but my stiffness is lessened a little.Ampyra is considerably more expensive than the compounded 4-AP. If you don't have health insurance that will cover the cost of Ampyra, you would be better off paying out-of-pocket for 4-AP.CarolynFrom: P <apurich8758@...>low dose naltrexone Sent: Mon, June 14, 2010 7:30:43 PMSubject: [low dose naltrexone] Walking Pill

What is the drug/prescription name for the walking pill?I have heard of 4ap, which some have claimed has helped with walking ability.