Re: Re: LDN and infertility

[Guest guest]

Thanks ,I scoured this site a couple of years ago when I first was looking into LDN - it really is interesting. I can see that LDN could modulate hormonal imbalances and that may be how it works to repair infertility.I looked again recently but could not find any direct references to their use of HDN throughout pregnancy. If you come across that info please alert me to it. This of great interest to me. I've seen one research paper on HDN in pregnant rats but that is all.By the way, the results were poor.Thanks for keeping me informed,JackieFrom: Bill Sigler <wesigler@...>Subject: [low dose naltrexone] RE: LDN and infertilitylow dose naltrexone Date: Tuesday, May 18, 2010, 10:04 PM

Dr. Hilgers also has had many years experience (over 25) giving LDN to pregnant and nursing mothers, and although it may be anecdotal, he reports that the mothers and babies are very healthy after using LDN. I believe he has used up to 100 mg on pregnant mothers without incidence. He has a great website for anyone with infertility/pms/ppd issues and just general women's health issues. A very caring doctor and wonderful Institute. I am currently taking LDN for PMS and it has really helped me. www.popepaulvi.com

[Guest guest]

On the second page of this brochure the endorphin surge is remarked on.This, it is thought, improves endorphin deficiency infertility.http://www.fertilitycare.net/documents/LDNInfoNov08al.pdfSome neurotransmitters, peptides, function as hormones as well. It has been thought for quite some time that LDN's stimulation of peptide production has modulating or regulating effect on homeostasis. Presumably this includes the protein and amino acid based hormones. These protein hormones include luteinizing hormone which is essential to

reproduction, likewise follicle stimulating hormone, another protein hormone, is essential to the process of ovulation.That's about all I know in this area. As for thyroxine, it is an amino acid based hormone, tyrosine in fact. I haven't had any significant improvement in my thyroid dysfunction either with LDN. I think tyrosine is more affected by dopamine than opioid peptides. That may explain the lack of improvement.But I can't tell you how or why.There is some discussion of increasing endorphin levels to improve fertility.http://autoimmunedisease.suite101.com/article.cfm/infertility_treatmentsJackie--- On Wed, 5/19/10, FrancieS <francie@...> wrote:From: FrancieS <francie@...>Subject: [low dose naltrexone] Re: LDN and infertilitylow dose naltrexone Date: Wednesday, May 19, 2010, 4:07 PM> Thanks ,> I scoured this site a couple of years ago when I first was looking into LDN - it really is interesting. I can see

that LDN could modulate hormonal imbalances and that may be how it works to repair infertility.I was under the impression that it was capable of doing a number of things, most importantly silently treating undetected cases of chronic endometriosis or other inflammations that affect fertility. I was not aware of it modulating hormone imbalances. Do you have reference to that? I have not found it doing that with me, although after a year, it has apparently lowered my need for so much thyroid medication.Franciehttp://LDN-for-MS.com My Story------------------------------------

[Guest guest]

I don't think it will be discovered that these substances in the body

always do one thing or another. I think it will be discovered that they

are used in different ways depending on individual biology and individual

need. That is why LDN helps such a wide range of illnesses. The body uses

the boost to fix what it needs to fix.

Remember that individual biology varies enormously from being to being.

Some human systems are vastly different than some others, I have heard it

said that some humans are so different from what might be the norm that

it's not understood quite how they function.

In any case, I think what will be found is that individuals vary widely.

I think it would be good if people stopped trying to generalize the issue

with thyroid dysfunction, because it's documented that people have regained

their thyroid function on LDN. Someone just discussed that they had to go

off their thyroid meds. Continuing to try to theorize why LDN doesn't fix

thyroid autoimmune is contrary to the facts, because in fact LDN does fix

some people's autoimmune thyroiditis.

also, FrancieS wrote:

>I was not aware of it modulating hormone imbalances. Do you have reference

>to that? I have not found it doing that with me, although after a year, it

>has apparently lowered my need for so much thyroid medication.

Not needing so much thyroid medication is an example of LDN modulating

hormone imbalances. And once again, another example of LDN improving

thyroid function.

with best wishes,

--

At 06:40 PM 5/19/2010, you wrote:

>On the second page of this brochure the endorphin surge is remarked on.

>This, it is thought, improves endorphin deficiency infertility.

>

><http://www.fertilitycare.net/documents/LDNInfoNov08al.pdf>http://www.fertility\

care.net/documents/LDNInfoNov08al.pdf

>

>Some neurotransmitters, peptides, function as hormones as well. It has

>been thought for quite some time that LDN's stimulation of peptide

>production has modulating or regulating effect on homeostasis. Presumably

>this includes the protein and amino acid based hormones. These protein

>hormones include luteinizing hormone which is essential to reproduction,

>likewise follicle stimulating hormone, another protein hormone, is

>essential to the process of ovulation.

>

>That's about all I know in this area. As for thyroxine, it is an amino

>acid based hormone, tyrosine in fact. I haven't had any significant

>improvement in my thyroid dysfunction either with LDN. I think tyrosine

>is more affected by dopamine than opioid peptides. That may explain the

>lack of improvement.

>But I can't tell you how or why.

>

>There is some discussion of increasing endorphin levels to improve fertility.

>

><http://autoimmunedisease.suite101.com/article.cfm/infertility_treatments>http:\

//autoimmunedisease.suite101.com/article.cfm/infertility_treatments

>

>Jackie

>

>

>

>

>From: FrancieS <francie@...>

>Subject: [low dose naltrexone] Re: LDN and infertility

>low dose naltrexone

>Date: Wednesday, May 19, 2010, 4:07 PM

>

> > Thanks ,

> > I scoured this site a couple of years ago when I first was looking into

> LDN - it really is interesting. I can see that LDN could modulate

> hormonal imbalances and that may be how it works to repair infertility.

>

>I was under the impression that it was capable of doing a number of

>things, most importantly silently treating undetected cases of chronic

>endometriosis or other inflammations that affect fertility. I was not

>aware of it modulating hormone imbalances. Do you have reference to that?

>I have not found it doing that with me, although after a year, it has

>apparently lowered my need for so much thyroid medication.

>

>Francie

><http://LDN-for-MS.com>http://LDN-for-MS.com My Story

~~~ There is no way to peace; peace is the way ~~~~

--A.J. Muste

[Guest guest]

I am trying to understand but I am lost at "these substances". What substances?It is already known that many peptides have multiple functions. One for instance is the opioid peptide [met5] enkephalin. It was first known as a neurotransmitter, then Zagon discovered its function as a growth factor. Serotonin is a neurotransmitter but it also functions as a regulator of bowel

motility.Bio-chemistries differ from person to person - some may be large differences but most of us fall into a fairly narrow range. There are differences by sex, by age, that are normal. Other differences can manifest as a result of disease processes. But in general we are biologically quite similar to each other and similar also to other primates.I'd like to point out that I did not make a generalized statement about thyroid dysfunction at all. Rather I mentioned that LDN has not improved MY thyroid noticeably, and that possibly it was due to the fact that thyroxine is related more to dopamine than opioid receptors. That certainly no way implies that LDN has not helped others with thyroid problems. Maybe you are reading intent into my words that is not there. There are very different sorts of thyroid dysfunction. I simply don't seem to have one that is helped by LDN.Enough on this subject. The neuropeptide families are extremely

complicated to understand and science has yet to map the interrelations between members of different families and how they influence each other. There is so much potential for variation because of the multitudinous ways in which they DO influence each other. But these are subtle influences, not gross, sometimes not even obvious to an astute observer. And they exist in each individual, complex and not yet well-understood, and susceptible to disruption from so many kinds of injury, also very subtle and gross as well.So for now we are all very fortunate to have LDN - I just would like to see many more people benefitting from

it.Jackie>>From: FrancieS <francie@...>>Subject: [low dose naltrexone] Re: LDN and infertility>low dose naltrexone >Date: Wednesday, May 19, 2010, 4:07 PM>> > Thanks ,> > I scoured this site a couple of years ago when I first was looking into > LDN - it really is interesting. I can see that LDN could modulate > hormonal imbalances and that may be how it works to repair infertility.>>I was under the impression that it was capable of doing a number of >things, most importantly silently treating undetected cases of chronic >endometriosis or other inflammations that affect fertility. I was not >aware of it modulating hormone imbalances. Do you have reference to that? >I have not found it doing that with me, although after a year, it has >apparently lowered my need for so much thyroid

medication.>>Francie><http://LDN-for-MS.com>http://LDN-for-MS.com My Story~~~ There is no way to peace; peace is the way ~~~~ --A.J. Muste------------------------------------

[Guest guest]

>Enough on this subject. The neuropeptide families are extremely

>complicated to understand and science has yet to map the interrelations

>between members of different families and how they influence each

>other. There is so much potential for variation because of the

>multitudinous ways in which they DO influence each other. But these are

>subtle influences, not gross, sometimes not even obvious to an astute

>observer. And they exist in each individual, complex and not yet

>well-understood, and susceptible to disruption from so many kinds of

>injury, also very subtle and gross as well.

The substances I was referring to are the endogenous opioids. What you just

said is exactly what I said: science does not understand how these things

actually work, and each person's body is going to utilize the influx of

endogenous opioids uniquely, given biological and environmental factors.

--

~~~ There is no way to peace; peace is the way ~~~~

--A.J. Muste

[Guest guest]

Francie,I know others who've had good improvement with thyroid issues with LDN. I had fullyexpected I would be one of them, but no luck. After two years I am still on the same dose of thyroxine. I am beginning to think LDN's effects on thyroid disease may have everything to do with what caused the dysfunction in the first place. I don't believe it's the same in everyone.JackieFrom: FrancieS <francie@...>Subject: [low dose naltrexone] Re: LDN and infertilitylow dose naltrexone Date: Thursday, May 20, 2010, 5:37 PM>

That's about all I know in this area. As for thyroxine, it is an amino acid based hormone, tyrosine in fact. I haven't had any significant improvement in my thyroid dysfunction either with LDN. I think tyrosine is more affected by dopamine than opioid peptides. That may explain the lack of improvement.But I can't tell you how or why.It took nearly a year for the LDN to lower our need for thyroid medication in myself and my husband. I am still impressed by the subtle improvements being made even when I think I cannot get any better :-)Franciehttp://LDN-for-MS.com My Story

[Guest guest]

"LDN is never a stand alone treatment"I have successfully been using LDN alone for cancer. Two years on LDN, no elevated markers, no tumors, no symptoms.JackieFrom: lindakcoach <lindakcoach@...>Subject: [low dose naltrexone] Re: LDN and infertilitylow dose naltrexone Date: Saturday, May 22, 2010, 3:21 PM

May I suggest: Whenever there are thyroid issues the adrenal issues need to be looked at and addressed also. That never happened for me. In the last month as I have done intense research on LDN and the many aspects of my autoimmune conditions, the thyroid/adrenal connection stands out above all the others for me. Check out www.stopthethyroidmadness.com and spend some time there reading their information. I only wished I knew all of this 15 years ago. Or even 30-45 years ago. As someone else on these Y-groups has previously stated, LDN is never a stand alone treatment. Over the years I have spend hundreds of dollars pursuing becoming well again and I and my treating professional care partners (conventional/allopathic medicine and alternative/integrative modalities ... doctors, pharmacists,

chiropractors, naturopaths, owners of health stores, and th

ose that just know a lot by their own self-education, plus my own research) never looked at the thyroid/adrenal connection or what set that off in the beginning. We all had pieces but not the whole picture until now. None of us knew this.

[Guest guest]

LDN is NOT "NEVER" a stand alone treatment.

LDN is ALL I take, or do you consider Eating Food, Drinking Water, taking some vitamins, Brushing your teeth, wiping your butt, part of the Treatment?

[low dose naltrexone] Re: LDN and infertility

May I suggest: Whenever there are thyroid issues the adrenal issues need to be looked at and addressed also. That never happened for me. In the last month as I have done intense research on LDN and the many aspects of my autoimmune conditions, the thyroid/adrenal connection stands out above all the others for me. Check out www.stopthethyroidmadness.com and spend some time there reading their information. I only wished I knew all of this 15 years ago. Or even 30-45 years ago. As someone else on these Y-groups has previously stated, LDN is never a stand alone treatment. Over the years I have spend hundreds of dollars pursuing becoming well again and I and my treating professional care partners (conventional/allopathic medicine and alternative/integrative modalities ... doctors, pharmacists, chiropractors, naturopaths, owners of health stores, and th ose that just know a lot by their own self-education, plus my own research) never looked at the thyroid/adrenal connection or what set that off in the beginning. We all had pieces but not the whole picture until now. None of us knew this.

[Guest guest]

Dr's Berkson, Bihari, Zagon, etc. do/did not generally recommend LDN as a stand alone treatment for cancer. I'm glad that both of you (Jackie and Larry) have had success with LDN as their only prescription medication (at least that seems to be what you are saying), but many of us are not so lucky. YMMV, and it's important to keep a close eye on what is happening with your cancer, whatever your current treatment decisions may be... cancer is tricky, and what works this month may not be as effective next month.And yes, nutrition, hydration, supplementation and hygiene are all generally considered part of one's treatment regimen by all but the very stodgiest and Tradition-bound of doctors. Oncologists and surgeons, for instance, ask for your current supplementation list at every appointment. They obviously consider that vitamins, minerals, etc are serious medicine that can affect not only your health but the behavior of any other treatments they might recommend for you.And whether it's considered an official treatment or not, I suspect that few doctors would want to have an awful lot to do with you if you never wiped your butt. I'm just saying...~EileenOn May 22, 2010, at 3:57 PM, LarryGC wrote:

LDN is NOT "NEVER" a stand alone treatment.

LDN is ALL I take, or do you consider Eating Food, Drinking Water, taking some vitamins, Brushing your teeth, wiping your butt, part of the Treatment? andJackie wrote:I have successfully been using LDN alone for cancer. Two years on LDN, no elevated markers, no tumors, no symptoms.

[Guest guest]

Yep.

My Dad was on Taxotere Chemo, once a week, for the first 6 months, and LDN daily; given 6 months to LIVE

After 6 months, when the CT showed his tumors shrunk in HALF, and the oncologists never saw THAT happen in their careers, they stopped the chemo, so then he was only on LDN 4.5 MG, and whatever diet and vitamins my sister thought would help.

3 months later they declared him in remission and stable

3 months after that another CT showed his tumors shrunk in HALF AGAIN

3 years and 2 months later... he's still walking, talking, driving, playing poker, enjoying what he can, and carrying on.

Re: [low dose naltrexone] Re: LDN and infertility

Dr's Berkson, Bihari, Zagon, etc. do/did not generally recommend LDN as a stand alone treatment for cancer. I'm glad that both of you (Jackie and Larry) have had success with LDN as their only prescription medication (at least that seems to be what you are saying), but many of us are not so lucky. YMMV, and it's important to keep a close eye on what is happening with your cancer, whatever your current treatment decisions may be... cancer is tricky, and what works this month may not be as effective next month.

And yes, nutrition, hydration, supplementation and hygiene are all generally considered part of one's treatment regimen by all but the very stodgiest and Tradition-bound of doctors. Oncologists and surgeons, for instance, ask for your current supplementation list at every appointment. They obviously consider that vitamins, minerals, etc are serious medicine that can affect not only your health but the behavior of any other treatments they might recommend for you.

And whether it's considered an official treatment or not, I suspect that few doctors would want to have an awful lot to do with you if you never wiped your butt. I'm just saying...

~Eileen

On May 22, 2010, at 3:57 PM, LarryGC wrote:

LDN is NOT "NEVER" a stand alone treatment.

LDN is ALL I take, or do you consider Eating Food, Drinking Water, taking some vitamins, Brushing your teeth, wiping your butt, part of the Treatment?

and

Jackie wrote:

I have successfully been using LDN alone for cancer. Two years on LDN, no elevated markers, no tumors, no symptoms.

[Guest guest]

Eileen,One correction Eileen - I take other Rx meds but not for cancer. I tried the standard of care therapies after surgery to remove the visible tumors, but they made me so ill I could not continue. I had new mets in my lungs that were very fast growing. One was biopsied and confirmed. By the time we were ready for the second to be biopsied both were gone. I'd had a spontaneous regression. But the cancer I have is relentless. I had suspected microtumors in my liver - I knew that because I was experiencing the kind of symptoms associated with liver tumors - symptoms known as carcinoid syndrome.That is when I found LDN. I discussed it with Dr. Zagon because I did

not want to take a drug I did not understand - how did it work, why did it work? He sent me a number of papers which I read assiduously over and over until I understood how LDN might work for me. I admit when I still had symptoms not that long ago I was discouraged. But I have improved so much since then.I am following a monitoring schedule of specialized scans and lab work. So far, so good.The beauty of LDN, unlike other kinase inhibitors, is that because there are no side effectsI do not have to stop taking it. Other kinase inhibitors cause terrible effects and then the cancer rebounds after disuse. It was very scary to me, looking at my options and then LDN appeared.End of story. Well not quite. I am now telling others in the cancer community about LDN.I have managed to introduce LDN to doctors and other professionals who have cancer. That is why the science is so important to me. I talk

about LDN to people who are living and working in science and medicine, and many others too. It's a vocation now. Next to brushing my teeth and wiping my butt.JackieI have successfully been using LDN alone for cancer. Two years on LDN, no elevated markers, no tumors, no symptoms.