Ciguatera

[Guest guest]

Re: Fw: CIGUATERA

In a message dated 1/26/03 1:48:31 PM Eastern Standard Time,

melillo3@... writes:

> DR. PEARN HAS WRITTEN DIRECTLY TO ME, THAT I COULD NOT HAVE

> ANYTHING

> RESEMBLING WHAT HE HAS RESEARCHED HIS ENTIRE LIFE.

Dr. Pearn is not a researcher. He is an M.D. and he never did any testing. And

I doubt that he understands that, although patients are highly positive to

ciguatera, that may not necessarily mean that it is the exact same thing.

That's what they're working on now as well as a lot of other things. And I

don't think Dr. Pearn understands that this isn't acute poisoning but that it is

being manufactured in the body. A lot of M.D.'s don't understand the research

part of this but we're just following the science as that's the only thing that

brings out the truth. There are some, dont get me wrong, that understand how

important this discovery is. A few have even gotten in touch with us to

congratulate us!

[Guest guest]

oops, my last post was meant for another group. you can look more into this

yourself though by going to Toxicology portion of this page:

http://www.ncf-net.org/library/library.htm and reading about the ciguatoxin that

shows up in

96% of CFSers and I think likely to show up in lymers too if they were tested.

jason

[Guest guest]

All I've been able to find is this website for the autistic unit at

Sunderland Uni.

http://osiris.sunderland.ac.uk/autism/hplc.htm

BW,

Sheila

> RE: Re: ciguatera

>

>

> That really sounds interesting - has it been published?

> J & S <jim.sheila@...> wrote:

> Thanks for all this, but if this ciguatera epitope is very similar to

> ciguatera toxin how are we still functioning!

> Recently I consulted Dr over here in UK who is finding, using dark

> field microscopy " borrelia-like " spirochaetes in very large numbers of his

> CFS patients (he is working in collaboration with a University and Dr Lida

> Mattman and Dr Harvey from the US)

> He is finding a common factor in 99.9% of these patients in a substance,

> IAG, in the urine.This substance and it's precursors disrupt biological

> membranes. Could this be the same thing as the ciguatera epitope

> that he is

> finding? Sorry if this is a really stupid question but it just struck me

> that both disrupt cell membrane functioning?

> This work on IAG is being done at Sunderland Uni by Prof Hooper at the

> Autism Unit.

> They find people with autism and that spectrum of conditions, GWS

> patients,

> CFS patients and people with organophosphate poisoning all have this

> chemical, IAG, in their urine, that shouldn't be there.

> In CFS this chemical is present in 99.9% of people,

> In autism 88%

> In families of autistic children 50%

> In normal mortals 15%

>

> I asked Dr W what caused this IAG in the urine and he said they weren't

> sure, could be genetic or environmental, infection or organophosphates or

> combinations thereof.

> IAG = trans-3(Indol-3-yl)Acriloglycine. It is an abnormal serotonin

> metabolite, a product of disturbed tryptophan metabolism.

> IAG increases membrane permiability so it increases gut and brain

> permiability, affects hypothalmic functioning and " higher executive

> functioning " and a negative effect on the immune system.

> Could they be one and the same thing?

> Whatever, this substance doesn't sound like a bundle of laughs to have

> swimming around your body either.

> BW,

> Sheila

>

> >

>

---

Outgoing mail is certified Virus Free.

Checked by AVG anti-virus system (http://www.grisoft.com).

Version: 6.0.622 / Virus Database: 400 - Release Date: 13/03/04