Dose quantity question for long-timers was: thank you!

[Guest guest]

Please read below for the context of the question I'm asking.

------------------------------

Well, I'm not convinced. The original researchers say 4.5mg max, with a few

exceptions for very large persons, because the drug otherwise stays in

circulation in the body too long. By that formula I would be taking even

more than 4.5mg, and I'm more inclined to take less, not more. This

definitely goes against the bulk of the information that is available.

Can any of the long-time people taking LDN speak to this issue, and to

whether this book and the formula is considered authoritative?

--

At 06:42 AM 5/13/2010, you wrote:

>This information is in the book, " The Promise of Low Dose Naltrexone " .

>

><http://tinyurl.com/26ug4f7>http://tinyurl.com/26ug4f7

>

>

>

>From: Baker <vbaker@...>

>Subject: Re: [low dose naltrexone] thank you!

>low dose naltrexone

>Date: Thursday, May 13, 2010, 12:55 AM

>

>I have not seen this information presented on any LDN website. Can you

>please give a source for this formula?

>

>--

>

> >The dosing formula is 0.08 mg naltrexone per kg (2.2lbs) of body weight

> >per 24 hours, with variations to account for differences in metabolic

> >rates and composition of body weight.

> >A very large muscular man or woman may do better on a higher dose of

> >naltrexone up approximately 10 mg.

> >

> >Jackie

~~~ There is no way to peace; peace is the way ~~~~

--A.J. Muste

[Guest guest]

It is general wisdom that we do not go over 4.5mg. The dose is more related to

opiod receptors than weight or size of person, which is why some small women are

comfortable with more than some large men. In extremes, the amount can change. A

cat uses .5mg and we use 5mg for 500 pound Friesian colts.

Francie

http:LDN-for-MS.com

>

> Please read below for the context of the question I'm asking.

>

> ------------------------------

> Well, I'm not convinced. The original researchers say 4.5mg max, with a few

> exceptions for very large persons, because the drug otherwise stays in

> circulation in the body too long. By that formula I would be taking even

> more than 4.5mg, and I'm more inclined to take less, not more. This

> definitely goes against the bulk of the information that is available.

>

> Can any of the long-time people taking LDN speak to this issue, and to

> whether this book and the formula is considered authoritative?

>

> --

[Guest guest]

What do you treat colts for?From: FrancieS <francie@...>Subject: [low dose naltrexone] Re: Dose quantity question for long-timers was: thank you!low dose naltrexone Date: Sunday, May 16, 2010, 3:57 PMIt is general wisdom that we do not go over 4.5mg. The dose is more related to opiod receptors than weight or size of person, which is why some small women are comfortable with more than some large men. In extremes, the amount can change. A cat uses .5mg and we use 5mg for 500 pound Friesian colts. Franciehttp:LDN-for-MS.com>> Please read below for the context of the question I'm asking.> > ------------------------------> Well, I'm not convinced. The original researchers say 4.5mg max, with a few > exceptions for very large persons, because the drug otherwise stays in > circulation in the body too long. By that formula I would be taking even > more than 4.5mg, and I'm more inclined to take less, not more. This > definitely goes against the bulk of the information that is available.> > Can any of the long-time people taking LDN speak to this issue, and to > whether this book and the formula is considered authoritative?> >

--------------------------------------

[Guest guest]

I follow Dr. Bihari's protocol of 4.5mgs which he considered the optimal adult

dosage. I have read the book you're referring to and many parts disagree with

what was successful for Dr. Bihari. I personally don't recommend the book to

anyone. I suggest new LDN users read Dr. Gluck's LDN website and a very few

others such as Dr. McCandless who has hands on experience with LDN and humans.

There is a lot of misinformation out there coming out the minds of 'instant

experts'.

Art

> >

> >From: Baker <vbaker@...>

> >Subject: Re: [low dose naltrexone] thank you!

> >low dose naltrexone

> >Date: Thursday, May 13, 2010, 12:55 AM

> >

> >I have not seen this information presented on any LDN website. Can you

> >please give a source for this formula?

> >

> >--

> >

> > >The dosing formula is 0.08 mg naltrexone per kg (2.2lbs) of body weight

> > >per 24 hours, with variations to account for differences in metabolic

> > >rates and composition of body weight.

> > >A very large muscular man or woman may do better on a higher dose of

> > >naltrexone up approximately 10 mg.

> > >

> > >Jackie

>

>

>

> ~~~ There is no way to peace; peace is the way ~~~~

> --A.J. Muste

>

[Guest guest]

Thank you, Francie, now that you say this I remember Dr Skip saying

this. It has to do with the number of opioid receptors in each individual

body, which varies widely and surprisingly, as you describe. Thanks for this.

--

>It is general wisdom that we do not go over 4.5mg. The dose is more

>related to opiod receptors than weight or size of person, which is why

>some small women are comfortable with more than some large men. In

>extremes, the amount can change. A cat uses .5mg and we use 5mg for 500

>pound Friesian colts.

>

>Francie

>http:LDN-for-MS.com

>

>

> >

> > Please read below for the context of the question I'm asking.

> >

> > ------------------------------

> > Well, I'm not convinced. The original researchers say 4.5mg max, with a

> few

> > exceptions for very large persons, because the drug otherwise stays in

> > circulation in the body too long. By that formula I would be taking even

> > more than 4.5mg, and I'm more inclined to take less, not more. This

> > definitely goes against the bulk of the information that is available.

> >

> > Can any of the long-time people taking LDN speak to this issue, and to

> > whether this book and the formula is considered authoritative?

> >

> > --

~~~ There is no way to peace; peace is the way ~~~~

--A.J. Muste

[Guest guest]

Author, Elaine A , the book on Low Dose Naltrexone, is included in some of the "official" LDN web sites. I was on her extensive web site yesterday. Very informative, well written and I learned new info. Google her and check it out.

[Guest guest]

To the contrary, reading the small amount of what she actually publishes on

her website (teasers for her books), what she says about LDN directly

contradicts the best practices developed by the primary researchers. She is

not a researcher. Suggesting that 10mg is the upper dose is just not in

line with the literature. She also says:

>In my experience, used short-term (4-5 months) for radioiodine-induced

>hypothyroidism, LDN has no effect on thyroid hormone levels.

First, she only herself took it for 4 to 5 months, but she claims to be an

expert (and says things that are not agreed on), yet the knowledge base

here on this list and the info websites says that 4-5 months would be a

minimum trial time, that it would take longer than that to know for sure,

and that LDN is taken for life. So she claims to be an expert based on

personal experience but she doesn't actually take LDN. Second, people have

been tested and have had reductions in their need for thyroid hormone

supplementation, so she is making general statements based on " her

experience " that do not reflect the experiences of many patients on LDN,

and using her status as a " published author " to assert herself as an

authority, when what she is saying is out of the norm.

She also denigrates the idea that taking it at night is most efficacious,

and I'm not convinced by her arguments. And, the info on LDN is all old,

she gives a summary of the 2007 annual LDN conference, and announces that

the Stanford fibromyalgia study is seeking participants, when in fact that

study has been finished with positive results.

So, I'm not impressed. I think she jumped on a bandwagon to get a book

published because there is a hunger for information. There may be info on

the website, but I'm not convinced that it is information that LDN patients

should be following.

--

>Author, Elaine A , the book on Low Dose Naltrexone, is included in

>some of the " official " LDN web sites. I was on her extensive web site

>yesterday. Very informative, well written and I learned new info. Google

>her and check it out.

>

>

>

>

>

>

>No virus found in this incoming message.

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>13:26:00

~~~ There is no way to peace; peace is the way ~~~~

--A.J. Muste

[Guest guest]

Obviously, you have checked out Elaine in much greater depth than I, and being a newbie with LDN, I don't have as much background as you. Thank you.