Lowdosenaltrexone - effect on lymphodema

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Dear readersFive years ago I had an right axillary clearance after a breast cancer operation. Four years ago I developed Relapsing Polychondritis. One and one half years ago, I got lymphodema in my right arm. It arrived at the same time at the same time as my forearm and hand became inflamed after some unaccustomed sanding and painting activity.Over time, the lympodema subsided to some extent but persisted until I started to take Celebrex as an anti-inflammatory for Relapsing Polychondritis, when the sore muscles and the lymphodema improved a little. Relapsing Polychondritis is an autoimmune disease in which the body can destroy its cartilage, connective tissue and interstitial tissue. One problem with Relapsing Polychondritis is that is is generally

diagnosed by its symptoms. Blood tests are often negative and a biopsy of affected cartilage can also be inconclusive and only cause more cartilage damage. I have spent years feeling silly as I described a raft of symptoms to my doctors, thinking they must think I am only a hypochondriac.For almost a year I have been a volunteer in a university trial to look at the effect of weight resistance training on lymphodema. I was randomly allocated to the control group (ie no treatment). I have had my affected arm meaured in many different ways many times during the last year. I have now been taking LDN for 6 months, and was looking forward to having my arm measured again as I felt that not only had LDN reduced my other symptoms, it had also reduced my lymphodema. That opportunity came today. Tests showed that, as I had predicted, I no longer had lymphodema The strength in both arms, especially the

right one, had increased greatly compared with what it was 6 months ago.Lympodema is increasingly being connected to inflammation in the affected part. It has been hypothesised that it could be due to inflammation in the deep muscle fascias. Hence it would seem logical that a reduction in infllammation could result in a reduction in lymphodema.The point of this posting is to suggest that:a) people who develop lympodema should take an anti-inflammatory medicationb) if the inflammation is caused by an autoimmune disease, the lympodema should decrease with the use of LDN, and c) an objective test for muscle inflammation could be in the measurement of the volume of the limb, its electrical impedence and the strength of the muscles in that limb. Have any other readers noticed the connection between muscle soreness and lymphodema, and found that LDN resulted

in improvement of the lymphodema? in AusFrom: zahavi <zahavi100@...>low dose naltrexone Sent: Tue, 5 January, 2010 7:15:11 AMSubject: [low dose naltrexone] Help?

just give a name .they do not check it or use it

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