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Timing question

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A friend of mine with Crohn's is going to try LDN soon. He has a work schedule that requires him to go to bed at 7 PM and get up at 3 AM. He's not going to get up a 9 PM to take the LDN. I told him he probably should not take it at 3 AM and just take it at bedtime, but I am far from being an expert so thought I'd ask.

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