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Neural Myopathy - Burning Feet

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Hi there.

I have peripheral neuropathy (PN) pains (feet and hands both) as a

result (just one of several symptoms) of having hyper-cortisolism

(specifically a rare form of Pseudo Cushing's).

I have been on LDN since mid December (very low dose initially, then

titrated gradually up to where by mid February was at the current

dosage of 4.5 mg).

I cannot say that I have noticed any help in that regard so far... but

then the damage began (most likely) in the late 1990s - definitely by

mid 2002 when just a couple of initial symptoms started (including the

PN) at a mild and sporadic level but then "exploded" (with a number of

other symptoms) in May of 2004. So I have had neurological damage

occurring since then (plus 7 years) so don't know if there would be a

noticeable degree of improvement (from over seven years) and expect to

see results that would be noticeable after just four months (and only a

couple of those at the therapeutic dosage of 4.5 mg).

My cortisol levels became normalized (for the first time since mid

2002) in August of 2009... and were normalized for the next 5 monthly

tests --- but then shortly after starting LDN, two of my three monthly

cortisol tests were back to reflecting elevated ranges (no where near

as highly elevated as 2 - 3 years ago, but my most recent available

test (from early March) did return with a result that was about the

same as where it was around January of 2009.

So I have a question as to whether or not the LDN was causing the rise

in the monthly cortisol testing in those two out of three months (I

won't have the test results back from the early April testing back

until probably the end of this coming week). Or, if not, did, during

the time frames where the cortisol levels naturally (through the Pseudo

Cushing's condition) were elevated, did that elevated cortisol level(s)

cause the LDN to work LESS successfully than it should otherwise be

doing??? (I know for example the taking prednisone, cortisone, etc. is

a "no-no" when taking LDN as it adversely affects the LDN's actions.

Meanwhile, I find that a diluted mixture of DMSO (1 part to 10 parts

distilled water) and Vitamin B-Complex along with extra Vitamin B5

"slightly" helps the PN..... for now.

-- If you forward this correspondence, PLEASE delete ("cut") the forwarding history which includes my email address. Also use the "BCC" feature when addressing emails - unless it is ONLY to me so that the email message does NOT display everyone else's email address. It is simply a COMMON COURTESY to me and to all others who may not wish to have their email addresses sent all over the world. Deleting the history and using the BCC feature also helps prevent Spammers from mining addresses and also prevents viruses from being propagated. Thank you!

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