Re:PE1296, LDN Now Petition to the ish Parliament Public Petition

[Guest guest]

According to the Health Committee report human trials have limited value in determining the effectiveness of drugs. This is a quote from chapter 4 of that report (The Influence of the Pharmaceutical Industry) 5 Apr 2005. Also as far as MS is concerned LDN is dose critical and therefore another problem when designing a clinical trial.

56. Human trials tend to have limited predictive value due to problems of extrapolation to routine clinical practice. Typically, only a small sample of the prospective population to be exposed to the drug can be studied in clinical trials. Furthermore, those patients who will probably be exposed to the drug if it is marketed may be excluded from clinical trials because they have multiple pathologies or take a number of different medicines. These co-morbidities and the presence of other drugs in the body might affect the drug being investigated and not allow accurate comparison with a placebo or comparator drug.

May be something you can draw to the attention of the petition committee?