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Re: Endorphins and ME/CFS

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Hi Fiona,

Do you have any links on that Glutathione/mitochondrial damage idea? Sounds

interesting. ~

>

> http://www.fiikus.net/?ldn

>

> Yes the above link again, but also written by somebody with ME/CFS. This

person found their ME/CFS to be progressive and fell ill a couple of years

before myself.

>

> " I could already notice benefits the very next day after I started taking it.

My fatigue and muscle weakness are a lot better, I don't " crash " nearly as

easily as I used to and the crashes are significantly milder (I could get

bedbound from very mild effort, like stirring a soup!). My cognitive problems

have improved though not as much as my fatigue. My chronic fever and chronic

urticaria, both among my most bothersome symptoms are 90-95% gone. My asthma is

also a lot better. Most importantly, LDN seems to have stabilized my condition.

I believe I would be in wheelchair, probably even nursing home, now if it wasn't

for LDN. While I'm far from a cure my quality of life is very much improved. "

>

> I have to say, this sounds profound and there is nothing to loose by giving it

a go!

>

> One thing that has always occurred to me is that my form of ME/CFS WAS a

persistent annual decline, with many relapses and remissions. It has clearly

affected the immunity and endocrine systems and until I treated the endocrine

system, there was a persistent annual decline.

>

> We all know that if you exercise, you release your endorphins. Yet if you are

really ill, you are bound to have restricted mobility. I have used mobility aids

and limiting walking to perhaps 5-10 mins a day. Such short distances to the

post box, to the corner shop etc. These distances are not enough to release your

endorphins. It's only enough to prevent too much deconditioning, and stops you

stiffening up too much.

>

> So if you don't produce many endorphins, I can see how that can affect the

immunity and this component may contribute to a downward decline in many

illnesses. Yet such downward declines are not really taken seriously by your GP

and you are just encouraged to do as much as you can. I was advised to nudge

forwards my walking (with disasterous consequences). I now believe this was due

to low Glutathione and mitochondria damage. So you can see why it may have been

a while since my body has naturally produced the endorphins it needs!

>

> Perhaps I really will have better time ahead, I have to believe that, or else

what am I here for and what am I using LDN for.

>

> I am aiming for optimum health and betwen optimum thyroid treatment (which

isn't there yet) and LDN and supplements, perhaps this is the way to give myself

a chance.

>

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