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Interesting Observation!!!!

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I've been taking LDN for 4+ months for FM and OA issues. I've had a tough time with dosing, from a low .5mg at the start to 2.5mg last Thursday. I was getting lots of muscle/joint pains at this 2.5mg dose so I've been off LDN for 3 days, the longest in the 4+ months I've started on it. The other times off LDN has been for 2 days.

My major positives with LDN have been more ENERGY, and trick finger much improved, and less overall pain.

I was almost in tears last Friday so I did stop the LDN and now my muscle/joint pains are just about gone but I still my normal joint issues, but the FATIGUE has returned. So what I'm saying with the LDN maybe out of my body the Fatigue has returned and joint issues somewhat improved from the 2.5mg dose.

I will start tomorrow on .5mg and stay there for who knows how long. Again, we are all so unique and with LDN the same goes as far as dosing.

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