Guest guest Posted March 13, 2010 Report Share Posted March 13, 2010 Hi Julee LDN suppose to stay active in your body only few hours in person with normal liver function. Since your liver is compromised I would stop taking LDN at least 3-4 days before the surgery to make sure it is completely out of your system before you get other opioids.After the surgery "Drug information Handbook" recomends not to use Naltrexone untill patient is opiod-free for 7-10 days. Since your liver is not 100% I would add few more days to it to be sure. Unfortunatelly no studies were done with LDN , just Naltrexone, so it is impossible to give exact answer, only educated guess. In terms what pain meds are safe for compromised liver, try to stay away from Tylenol and combos of Tylenol(acetominophen) with Narcotics. Tylenol is very hard on your liver. If you absolutely have to take it, take N-acetylcysteine with it for protection 600 mg twice a day with juice high in vitamin C.Motrin,Advil and other NSAIDS not great too especially in high doses.Some narcotic pain killers, like Oxycodone are safer for liver but you can not use them together with LDN. Meds usually used during surgery like Morphine, Midazolam are not too bad for your liver.During your hospital stay you would not have control of what you get anyway, but I would advise to keep reminding every doctor and nurse seeing you and writing orders for you about your liver problems and making sure what they give is not bad for your liver.Better to be annoying and keep repeating the same thing again and again than risking somebody will give you med that can damage your liver. Also if you need antibiotics after surgery, be careful and doublecheck with your hepatologist, a lot of them can be toxic to liver. Best of luck .. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 13, 2010 Report Share Posted March 13, 2010 Excellent advice about how to manage one's care in the hospital. I wanted to quote Dr Skip's last advice (of which I am aware) regarding the length of time to wait (these were posted by Art in response to this query a couple months ago). As he said, it could have been just the particular individuals. fyi. -- >Heretofore I have recommended a day or two until this morning. A patient >was off LDN for 2 days and did not get any analgesia after a procedure. I >now recommend no less than 1 week. >Dr.Skip > >I too have recommended a day or two before surgery/procedures UNTILL THIS >AM. Got a call from a lady who had a colonoscopy and was given a " bunch " >of opiod analgesics. Nothing helped her pain. The kinetics strong suggest >that it should have worked but it didn't. Now it could have been a >metabolism problem, could have been a specific patient issues, could have >been anything. I am now going to recommend at least one week, just to be sure. >Dr.Skip >Hi Julee >LDN suppose to stay active in your body only few hours in person with >normal liver function. Since your liver is compromised I would stop taking >LDN at least 3-4 days before the surgery to make sure it is completely out >of your system before you get other opioids.After the surgery " Drug >information Handbook " recomends not to use Naltrexone untill patient is >opiod-free for 7-10 days. Since your liver is not 100% I would add few >more days to it to be sure. Unfortunatelly no studies were done with LDN , >just Naltrexone, so it is impossible to give exact answer, only educated >guess. In terms what pain meds are safe for compromised liver, try to >stay away from Tylenol and combos of Tylenol(acetominophen) with >Narcotics. Tylenol is very hard on your liver. If you absolutely have to >take it, take N-acetylcysteine with it for protection 600 mg twice a day >with juice high in vitamin C.Motrin,Advil and other NSAIDS not great too >especially in high doses.Some narcotic pain killers, like Oxycodone are >safer for liver but you can not use them together with LDN. Meds usually >used during surgery like Morphine, Midazolam are not too bad for your >liver.During your hospital stay you would not have control of what you get >anyway, but I would advise to keep reminding every doctor and nurse seeing >you and writing orders for you about your liver problems and making sure >what they give is not bad for your liver.Better to be annoying and keep >repeating the same thing again and again than risking somebody will give >you med that can damage your liver. Also if you need antibiotics after >surgery, be careful and doublecheck with your hepatologist, a lot of them >can be toxic to liver. Best of luck .. > > > > > >No virus found in this incoming message. >Checked by AVG - www.avg.com >Version: 9.0.790 / Virus Database: 271.1.1/2742 - Release Date: 03/12/10 >13:33:00 ~~~ There is no way to peace; peace is the way ~~~~ --A.J. Muste Quote Link to comment Share on other sites More sharing options...
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