Guest guest Posted January 28, 2010 Report Share Posted January 28, 2010 > > > Perhaps more of the spirochetes (in my case) are vulnerable at that time. I hear they have a 3-4 week reproductive cycle. the reproduction time of Bb is 7-20 hours in vitro, maybe in the human host a bit longer. So the +/- 4 week cycle is not directly related to that. The 4 week cycle is thought to be the result of interaction between Bb and our immune system, but nobody knows for sure. It could also be the result of Bb changing its antigens in response to effective adaptive immune respons (this takes a few weeks, and as soon as it is effective Bb will change its coat to evade immune detection). And of course hormonal cycles can play a part (are the flare cycles more obvious in women?). It is suggested that the flare cycle depends on pathogen load and is usually stronger during ABX course. Another theory (from Burrascano?) is that you have to start ABX at the moment your symptoms are worst, because that is the time the chetes are probably most active. Others simply treat for at least three months or so, in order to make sure that you go through several Bb (flare) cycles. It would help if we really knew what these 'cycles' are ... > Perhaps different strains of borrelia respond differently to antibiotics. yes, I'm sure that is the case. So if one AB type does not have any effect, try another one (of a different ABX class). > The nurse reassured me that because I will have had 3 months of oral Ceftin when I switch to Rocephin I shouldn't have a big herx. yes, agree > She joked that many patients don't want to come off IVs when they are told it's time because they feel so good and are afraid of relapsing. Well time will tell. agree as well, but you can't imagine how happy I was to get rid of the PICC lines after 6 weeks (they had to punch new ones every few days because they got rejected; my record was 7 days ...). > I have Buhner's book and all the essential herbs. I'm not comfortable taking them without supervision (there is an naturopath 45 miles away who uses Buhner's protocol) while on antibiotics. AFAIK catsclaw can be hard on the liver, haven't heard of the other ones (if I remember correctly, said that knotweed/smilax are supportive of liver function). Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 28, 2010 Report Share Posted January 28, 2010 Herx effects generally occur at the beginning of treatments, also following the cycles of the bactery (3-4 weeks). Believe me or not, I have cycle according to the full moon, even if being not a vampire! Herx also typically occur when switching form a treatment to an other, especially to treatment being not in the same familly. For instance, I had terrible herx when switching from Biaxin to rocephin, it was even not able to talk. Since ceftin is the same family than rocephin, this would limit herxing, but I'm not sure. You can ask for low dose at the beginning and slowly building. Also, in my case IM rocephine was as effective as IV, but it is painfull. I also experienced mild herx during all treatement long, which is very boring. Philippe > > > Since starting oral antibiotics 8 months ago: Doxycycline 1 month, 3 months amoxicillin, 2 months Zithromax (1 month paired with mepron, the other with Ceftin), and now one month with Ceftin & Biaxin, I started to see a pattern of feeling much worse symptoms around the beginning of third week of each monthly antibiotic cycle that lasts up to a week. Has anyone had a similar experience? Perhaps more of the spirochetes (in my case) are vulnerable at that time. I hear they have a 3-4 week reproductive cycle. I think the Biaxin is helping a little, certainly for me better than Zithromax. Perhaps different strains of borrelia respond differently to antibiotics. I did notice quite an improvement with Amoxicllin and then plateaued. > > I have a lot of confidence in the LLMD practice I'm with (20 yrs experience treating, founding member of ILADS & involved in research) They think it's time for me to begin IV treatment. I am quite concerned about having a major herx reaction on IVs because more of the antibiotics penetrate deeper into tissues and also into the brain. The nurse reassured me that because I will have had 3 months of oral Ceftin when I switch to Rocephin I shouldn't have a big herx. She joked that many patients don't want to come off IVs when they are told it's time because they feel so good and are afraid of relapsing. Well time will tell. > > I have Buhner's book and all the essential herbs. I'm not comfortable taking them without supervision (there is an naturopath 45 miles away who uses Buhner's protocol) while on antibiotics. My LLMD is OK with herbs, but wants to know which ones, because some are hard on the liver when taking antibiotics. For example, no colloidal silver during abx treatment. > > Kim > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted January 29, 2010 Report Share Posted January 29, 2010 > Believe me or not, I have cycle according to the full moon, even if being not a vampire! I have heard that more often (also for many other illness) but I'm pretty sure in most cases it is because - to an untrained observer - the moon looks full almost half the month, while most people will spot a new moon almost never, and the half moon is only half for a few days a month. I would be interested to see the statistics for those with and without astronomica background Quote Link to comment Share on other sites More sharing options...
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