Guest guest Posted March 29, 2010 Report Share Posted March 29, 2010 These links do not work > > http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news_view > <http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news_view > & newsId=20100329005235 & newsLang=en> & newsId=20100329005235 & newsLang=en > > > > www.lyme-resource.com <http://www.lyme-resource.com/> > You can lead a person to a fact, but you can't make them think! - > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 29, 2010 Report Share Posted March 29, 2010 Google new lyme test Milford Research lab. I spoke to one of the representatives from there today. Very informative. It appears the test is really good for quick response once bitten and if have swollen joint they can actually drain fluid from joint and test it. Very nice man and very willing to answer all questions. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 29, 2010 Report Share Posted March 29, 2010 Here's a tiny url version that will work... http://preview.tinyurl.com/ybw4sk7 [ ] Re: New lyme test These links do not work > > http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news > _view > <http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=new > s_view & newsId=20100329005235 & newsLang=en> > & newsId=20100329005235 & newsLang=en > > > > www.lyme-resource.com <http://www.lyme-resource.com/> You can lead a > person to a fact, but you can't make them think! - > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 29, 2010 Report Share Posted March 29, 2010 Here is the correct link: http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news_view <http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news_view & newsId=20100329005235 & newsLang=en> & newsId=20100329005235 & newsLang=en You may need to cut and paste the link text into the address bar of your web browser for it to work correctly. If, within this message, the URL wraps onto another line, you may have to remove one or more extraneous characters like " > " and " < " . From: [mailto: ] On Behalf Of Sent: Monday, March 29, 2010 8:41 PM Subject: [ ] Re: New lyme test These links do not work > > http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news_view > <http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news_view > & newsId=20100329005235 & newsLang=en> & newsId=20100329005235 & newsLang=en > > > > www.lyme-resource.com <http://www.lyme-resource.com/> > You can lead a person to a fact, but you can't make them think! - > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 29, 2010 Report Share Posted March 29, 2010 surf the menu bar for news, you can find the article there. Steve C. From: <lalaland2381@...> Subject: [ ] Re: New lyme test Date: Monday, March 29, 2010, 5:41 PM Â These links do not work > > http://www.business wire.com/ portal/site/ home/permalink/ ?ndmViewId= news_view > <http://www.business wire.com/ portal/site/ home/permalink/ ?ndmViewId= news_view > & newsId=20100329005 235 & newsLang= en> & newsId=20100329005 235 & newsLang= en > > > > www.lyme-resource. com <http://www.lyme- resource. com/> > You can lead a person to a fact, but you can't make them think! - > > > > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 30, 2010 Report Share Posted March 30, 2010 > > Google new lyme test Milford Research lab. I spoke to one of the representatives from there today. Very informative. It appears the test is really good for quick response once bitten and if have swollen joint they can actually drain fluid from joint and test it. Very nice man and very willing to answer all questions. do you know the cost of this test (for blood sample), compared to standard PCR tests? The news stories are not very clear about the additional value of this test. For those with some background check the Pubmed abstract: http://www.ncbi.nlm.nih.gov/pubmed/20231610 Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 30, 2010 Report Share Posted March 30, 2010 Cost of test? I did not ask - but if you call Millford Hospital they should be able to tell you. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 30, 2010 Report Share Posted March 30, 2010 > > Cost of test? > > I did not ask - but if you call Millford Hospital they should be able to tell you. I'm from Europe, so that is a bit impractical. I just wondered if this test is financially attractive. This is important because the test is extremely cheap (in EU they say the cost for the lab/hospital is about EUR 2.70 per test; a PCR tests costs at least 10x as much). Because PCR testing is mostly computer technology, the cost can go down strongly when they run enough automated tests. As long as PCR is relatively expensive, insurance companies have a strong incentive to cling to the old, bad . Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 30, 2010 Report Share Posted March 30, 2010 I couldn't get 's link to work, but here's the article: Early Lyme Disease DNA Test Reported in Upcoming April Paper in American Journal of Clinical Pathology Connecticut team at Milford Hospital develops test to identify patients with spirochetemia for swift treatment MILFORD, Conn.--(BUSINESS WIRE)--Many of the more than 30,000 people a year in the United States with suspected cases of Lyme disease spirochete (bacterial) infection can now take a DNA test developed by a Connecticut scientist/physician and his team that can quickly determine if they test positive for Lyme spirochetes in their blood. This is the first such early Lyme test available, and most insurance companies have already agreed to cover the cost for their members. " If people are infected with the Lyme spirochetes, and not treated quickly, thousands may suffer for many years from the debilitating effects of the disease. " The scientific medical paper about the advanced test will be printed in the April 2010 edition of the " American Journal of Clinical Pathology. " " If people are infected with the Lyme spirochetes, and not treated quickly, thousands may suffer for many years from the debilitating effects of the disease. " But if, after infection, the bacteria are identified without delay, the patient can be effectively treated and totally cured, " said Connecticut physician Sin Hang Lee, MD. There have been other PCR tests for early Lyme disease. But this is the first effective one using nested PCR for detection and DNA sequencing to validate the molecular diagnosis, in clinical laboratory medicine. DNA sequencing is accepted as the gold standard for molecular identification, said Dr. Lee. Dr. Lee, a pathologist, and his colleagues at Milford Hospital (Milford, CT) have developed the first highly sensitive and specific DNA test for the diagnosis of early Lyme diseasebefore the traditional serology lab tests become positive. If the clinician awaits the rising Lyme disease antibody titers (which is normally the case) to make a diagnosis, the diagnosis of Lyme disease may be delayed, or even missed. The literature reports that up to 75% of the patients with acute-phase Lyme disease are negative for the characteristic antibodies, but in fact the percentage is higher, he said. Lyme disease is spread by black-legged ticks, also known as deer ticks, and is most common in Connecticut, Massachusetts, land, Minnesota, New Hampshire, New Jersey, Delaware, Pennsylvania, New York and Wisconsin, according to the Centers for Disease Control. The spirochete bacteria enter the skin at the location of the tick bite. After an incubation for 3-30 days, the bacteria travel through the skin and may spread to lymph nodes or travel through the bloodstream to other organs and other skin sites. In technical terms, the new LoTemp® nested polymerase chain reaction (PCR) method detects a genomic DNA of the Lyme disease-causing spirochete in the blood, which is further validated by DNA sequencing. It is the marriage of both that minimizes false-negatives to the lowest possible and eliminates false-positives known to be associated with other Lyme disease DNA tests. Symptomatic patients visiting the emergency department or the walk-in center have the best chance for an early diagnosis by this new test. The waiting for a scheduled visit to the doctor's office usually misses the window of opportunity in DNA detection at the time when the bacteria are circulating in the blood of the patient in early Lyme disease, but only briefly, said Dr. Lee. Dr. Lee is also now collecting data and writing a second report for publication with Jay Walshon, MD, chairman of Emergency Medicine at Milford Hospital and Jessie , MD, of the Milford Hospital Walk-in Urgent Care Center, to summarize their experience. Milford is a suburban city outside of New Haven, in southern Connecticut. The region has about 600,000 people and is located less than an hour from Old Lyme, from which Lyme disease was named. Lyme disease is endemic in the suburban towns in and around the Milford area, which although located by Long Island Sound, is also in many areas heavily wooded. Dr. Lee's group reported that 25-50% of the engorged deer ticks removed from the human skin bites in this area were found to be infected by the Lyme disease causing spirochetes, Borrelia burgdorferi. Although the new method based on the nested PCR technology is highly sensitive in detecting Lyme spirochete DNA, a negative result still does not rule out Lyme disease because spirochetemia is transient and its time points in Lyme borreliosis vary from patient to patient, said Dr. Lee. Dr. Lee said, " untreated or inadequately treated patients may develop tissue damages in the joints, the heart and the nervous system as a result of the bacterial infection. Since there were no reliable laboratory tests to confirm the clinical diagnosis, Lyme disease has been both over-diagnosed and under-diagnosed. Erroneous over-diagnoses of Lyme disease may cause unnecessary use of antibiotics which are associated with serious undesirable side effects in certain patients. " Every positive DNA test result at Milford Hospital is confirmed by DNA sequencing, and the diagnostic signature sequence validated by the GenBank database, said Dr. Lee. The GenBank is an on-line database of publicly available DNA sequence data maintained by the National Center for Biotechnology Information (NCBI), a part of the National Institutes of Health (NIH). The physicians at the Milford Hospital Emergency Center and Walk-in Urgent Care Center, who see about 40,000 patients a year, usually order the traditional antibody testing and the new DNA test for patients presenting with Lyme disease-like symptoms. Most insurance companies except Aetna will pay for the test. Patients and physicians interested in information on this DNA test may call Poole, manager of Milford Medical Laboratory, at 203-876-4496. > > http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news_view > <http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news_view > & newsId=20100329005235 & newsLang=en> & newsId=20100329005235 & newsLang=en Quote Link to comment Share on other sites More sharing options...
Guest guest Posted March 30, 2010 Report Share Posted March 30, 2010 Hiya - there's another mention too at http://www.wtnh.com/dpp/news/health/milford-new-test-lyme-disease New test for Lyme disease Published : Monday, 29 Mar 2010, 5:12 PM EDT Jocelyn Maminta Milford, Conn. (WTNH) - A new test will help diagnose Lyme disease earlier, leading to more effective treatment. As warm weather approaches so does the season of ticks and Lyme disease. Infected deer ticks are the culprits. " This is a definitive molecular diagnosis of Lyme disease, " explained Dr. Sin Hang Lee, Milford Hospital. It took a year and a half in the research lab at Milford Hospital for Dr. Lee to develop a definitive way to diagnose Lyme disease using the DNA of the Lyme bacteria. " This is the first using DNA sequencing to confirm diagnosis of Lyme spirochete DNA, " Dr. Lee said. But the window of opportunity is short. Key to this test is when the blood is drawn. Dr. Lee says it should be done on the onset of symptoms - clear evidence the bacteria is in a patient's blood. " Every patient is different because from the time of the tick bite to symptoms, it may take three days, it may take 30 days, " he said. The sample is amplified twice to ensure a DNA match. Dr. Lee points out if there's a positive result it leads to early treatment. More on the test has been publishes in the latest American Journal of Clinical Pathology. > > > > http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=news > > _view > > <http://www.businesswire.com/portal/site/home/permalink/?ndmViewId=new > > s_view & newsId=20100329005235 & newsLang=en> > > & newsId=20100329005235 & newsLang=en > > > > > > > > www.lyme-resource.com <http://www.lyme-resource.com/> You can lead a > > person to a fact, but you can't make them think! - > > > > > > Quote Link to comment Share on other sites More sharing options...
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