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Re: Clostridium difficile: Curcumin seems to offer protection

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>

> I found the text below at lymenet.org, haven't seen it here. Anyway, this

research seems to suggest that 2 - 4 grams of curcumin/day inhibits Clostridium

difficile.

> Very important if you're on antibiotics. I'm mixing it with my Buhner herbs.

I haven't used ABX for three years now, but I did have Clostridium infection

after my ABX course (painful, I don't think I have it now).

This was despite using good quantities of Metronidazol (used against Bb cysts,

but it also is the official medication against Clostridium - go figure ...).

> C. difficile is resistant to many commonly used antibiotics; one treatment

approach now being tested involves transplanting feces from a healthy person

into the ill person's colon in order to restore normal bacterial balance. But

the new study suggests that turmeric could help prevent these infections in the

first place.

I think that in 5-10 years we will be using a modified (and IMHO safer) version

of this, adding just the right probiotics mix to 'kickstart' a more health

microbiome in the colon. Very promising approach for a lot of complicated health

issues.

Maybe equivalent to changing your diet so that the right bacteria thrive in your

colon ...

> Dr. Patel said in an interview that he undertook his study after researchers

from Singapore reported that Indian patients had the lowest rates of C.

difficile infection.

sure, I think it works well if you use it continuously in lower dose, like

people in India do.

> By giving people up to 4 g/day of curcumin, Dr. Patel said, it's possible to

obtain a concentration of curcumin in the stool well above the concentrations

that inhibited C. difficile growth. In regions where curcumin is a regular

dietary ingredient, he added, people typically consume 2 to 4 g/day, and up to

12 g/day can be safely consumed.

4 gram is a lot IMHO. I have read somewhere about potential risks involved at

this dose (for EU/US patients probably), but don't remember specifics. This

single dose is equivalent to at least hundreds of normal curry meals ... I

wonder how people get up to 4 gram a day with normal meals??

> Key questions that still must be resolved, he added, include figuring out

whether curcumin affects the absorption of other medications, and whether it

would be best to use the spice in capsules or as a food additive.

so too early to tell ... but if it works I would certainly prefer it to other

medications like metronidazol (which is considered carcinogenic, depending on

dose/duration).

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more about the bacteria tranfer method mentioned below:

" Last-ditch method at fighting intestinal superbug "

http://news./s/ap/20101214/ap_on_he_me/us_med_healthbeat_stool_transpla\

nts

" Using good bacteria to fight off the bad by transplanting stool from a healthy

person into the sick person's colon.

Reports of several dozen cases in a medical journal and at a meeting of the

nation's gastroenterologists this fall suggest that with no more inconvenience

than a colonoscopy, people who have suffered C-diff for months, or longer, can

rapidly improve.

An entire bacterial neighborhood is transplanted, almost like an organ

transplant minus the anti-rejection drugs, says Dr. Khoruts of the

University of Minnesota. "

> >

> > I found the text below at lymenet.org, haven't seen it here. Anyway, this

research seems to suggest that 2 - 4 grams of curcumin/day inhibits Clostridium

difficile.

> > Very important if you're on antibiotics. I'm mixing it with my Buhner herbs.

>

> I haven't used ABX for three years now, but I did have Clostridium infection

after my ABX course (painful, I don't think I have it now).

> This was despite using good quantities of Metronidazol (used against Bb cysts,

but it also is the official medication against Clostridium - go figure ...).

>

>

> > C. difficile is resistant to many commonly used antibiotics; one treatment

approach now being tested involves transplanting feces from a healthy person

into the ill person's colon in order to restore normal bacterial balance. But

the new study suggests that turmeric could help prevent these infections in the

first place.

>

> I think that in 5-10 years we will be using a modified (and IMHO safer)

version of this, adding just the right probiotics mix to 'kickstart' a more

health microbiome in the colon. Very promising approach for a lot of complicated

health issues.

> Maybe equivalent to changing your diet so that the right bacteria thrive in

your colon ...

>

>

> > Dr. Patel said in an interview that he undertook his study after researchers

from Singapore reported that Indian patients had the lowest rates of C.

difficile infection.

>

> sure, I think it works well if you use it continuously in lower dose, like

people in India do.

>

>

> > By giving people up to 4 g/day of curcumin, Dr. Patel said, it's possible to

obtain a concentration of curcumin in the stool well above the concentrations

that inhibited C. difficile growth. In regions where curcumin is a regular

dietary ingredient, he added, people typically consume 2 to 4 g/day, and up to

12 g/day can be safely consumed.

>

> 4 gram is a lot IMHO. I have read somewhere about potential risks involved at

this dose (for EU/US patients probably), but don't remember specifics. This

single dose is equivalent to at least hundreds of normal curry meals ... I

wonder how people get up to 4 gram a day with normal meals??

>

>

> > Key questions that still must be resolved, he added, include figuring out

whether curcumin affects the absorption of other medications, and whether it

would be best to use the spice in capsules or as a food additive.

>

> so too early to tell ... but if it works I would certainly prefer it to other

medications like metronidazol (which is considered carcinogenic, depending on

dose/duration).

>

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>

> more about the bacteria tranfer method mentioned below:

>

> " Last-ditch method at fighting intestinal superbug "

>

>

http://news./s/ap/20101214/ap_on_he_me/us_med_healthbeat_stool_transpla\

nts

as they say, nothing new and unproven treatment up to now; all these articles

based on a few cases that were published recently in a medical journal. I'm

pretty sure that with the over 1000 different bacterial species that are

'transplanted', you will also get some less pleasant bugs.

The problem is that the gut bacteria have to match your body, your genetics etc.

It is impossible to do that this way.

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I wouldn't be too quick to say it is impossible.

These cases were done under scientific scrutiny, and they did work, if you read

the article.

Needs more investigation for sure, but it is certainly something that the

scientific/medical community should follow up.

I have my doubts as to whether or not it will ever be investigated on a large

scale, since there are no drug involved, hence no profit for Big Pharma. Big

Pharma would prefer everyone take a pill for every condition.

> >

> > more about the bacteria tranfer method mentioned below:

> >

> > " Last-ditch method at fighting intestinal superbug "

> >

> >

http://news./s/ap/20101214/ap_on_he_me/us_med_healthbeat_stool_transpla\

nts

>

> as they say, nothing new and unproven treatment up to now; all these articles

based on a few cases that were published recently in a medical journal. I'm

pretty sure that with the over 1000 different bacterial species that are

'transplanted', you will also get some less pleasant bugs.

>

> The problem is that the gut bacteria have to match your body, your genetics

etc. It is impossible to do that this way.

>

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>

> I wouldn't be too quick to say it is impossible.

> These cases were done under scientific scrutiny, and they did work, if you

read the article.

> Needs more investigation for sure, but it is certainly something that the

scientific/medical community should follow up.

I don't think it is impossible at all, I just think it is not the most

attractive solution.

> I have my doubts as to whether or not it will ever be investigated on a large

scale, since there are no drug involved, hence no profit for Big Pharma. Big

Pharma would prefer everyone take a pill for every condition.

of course there is big profit involved, as this is a 'medical procedure' and

they will probably try to keep it like that. The doctors who use the procedure

will make lots of money from it.

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