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Schardt / fluconazole

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> In this study 8/11 patients were clinically cured and 3/11 were improved after

3weeks of treatment with fluconazole. This was in the European Journal of

Medical Research. Apparently fluconazole has an inhibitory impact on a

cytochrome P450, which incapacitates the Borrelia spp. upon longterm exposure

with it. He says that may-be a longer treatment would have improved the results.

but after those few publications things became silent, I checked it 1-2 years

ago and did not find any recent info. I don't think there has been much followup

on this protocol. My guess is that, like many other alternative treatment

protocols, it works for a select group of patients only (maybe those who failed

on standard antibiotics).

> I am going to look into it further and a month of fluconazole treatment can be

be overcome. It does affect the liver and it has some interactions with some

other medications.

it doesn't sound very safe to me. P450 is important, it is not a good idea to

shut it down for too long.

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