Re: Testing, MS and Coinfections and Bb prophage

[Guest guest]

>

> > keep in mind that the cystbusters do other things, like activating the

prophage (virus) in Borrelia. It could be doing all kinds of things, difficult

to predict.

>

> Huh??? The prophage (virus).... Tell me more please!!

I wrote an article about that and other research subjects that may provide

future treatment options. It should be available in print and online in a month

or so, but it is in Dutch. It is part of a citizen request for new Lyme

guidelines/treatment to our Parliament. They planned to translate it into

english and spread to foreign lyme organisations, not sure about current status

though. I will post when it is available, at least there are some funny Borrelia

cartoons for non-Dutch readers

for now, you can check some of the cartoons about lyme testing:

(use Google translate for the text in the pictures ...)

http://www.lymevereniging.nl/file.php?id=178

Bb prophage, in short:

All Bb strains that cause Lyme disease (Bb sensu lato) or relapse fever (some

other Bb strains) have a so called prophage called phi-BB1, located on the cp32

plasmid. The prophage is a gene, part of the Borrelia DNA, that can get

activated in very specific conditions. When activated it is a recipe to make

phages, a bacterial virus that will kill the Borrelia from inside.

phiBB1 gets activated by adverse conditions, e.g. when the bacterial DNA is

damaged by chemicals like flagyl or tinidazole. Flagyl is even used in the lab

to produce the prophage, it is a very reliable 'cue'.

This virus kills the Borrelia by making holes in its outer layers. It then

spreads inside the host, where it probably will find and kill other Borrelia.

The phiBB1 phage also exist in very small numbers in Bb cultures; scientists are

not sure what its function is. It may help to 'revatalize' old Bb cultures by

killing off most of the bacteria and stimulating them to regrow.

So, it almost seems as if Bb has some built-in 'self-destruct button'. Maybe we

can use that to get rid of it. On the other side, the phage might be dangerous

because there is evidence for transfer of Borrelia DNA to humans (research from

Alan Mc with Alzheimer patients). We don't know what mechanism is causing

that, but the prophage is a likely cause (similar to retroviruses).

So, activating the prophage kills the Borrelia, but may cause DNA damage in the

host. I wouldn't be surprised if this is related to the 'Gates of Hell'

experience that many people know from taking high doses of Flagyl.

Borrelia also has a second resident phage, but very little is known about that

at this time.

> > I had lots of MS-like lesions on the MRI in 2006; he told me then that

sometimes they disappear. But maybe that isn't even necessary for recovery, our

brains are very flexible.

>

> Lesions disappear? Yeah, I guess some disappear but new ones take their place.

So what do they say you have?

Some neurologists suggested I had MS, but because of my tick byte, EM and

Western blot and symptoms my neurologist at the time was sure it was chronic

Lyme.

He thinks Lyme lesions in the brain look a bit different than MS lesions, but I

don't think there is consensus about that. He is one of the very few in

Netherlands who wants to treat chronic lyme with more than two weeks of ABX, and

was put under severe pressure to stop treating lyme patients. Same problem as in

US, Canada etc.

> And how can they deny you coverage if you have brain lesions?

I'm offically 'treated' as far as Lyme is concerned (I had way more than two

weeks, so they are done with me). They probably dumped me because I got liver

damage and gallstones after the ABX treatment, I'm now a risk factor for the

hospital, so they don't want anything to do with me. I don't have anything in

writing though, just could not get any appointments, doctors on the phone etc.

for three years.

Ridiculous when you pay healthcare insurance, but that is how it works with LD.

> They won't accept a daignosis of Lyme Disease here but they have to accept MS

if a person has brain lesions and symptoms. As far as money goes, if the guys

that dole out the cash will not pay for LD and will pay for MS then as far as

they are concerned I have MS...for now anyway.

I know the neurologist is interested to follow my case, also because I write

some scientific articles to support the lyme organisation. So I think he is

going to treat my symptoms without saying it is Lyme. W'll see. In my case MS

diagnosis would no longer work, because I have hardly any neuro symptoms (only

the neuropathy which causes some issues in hand and feet - but that is not

specific for MS).

[Guest guest]

> I wrote an article about that and other research subjects that may provide

future treatment options. It should be available in print and online in a month

or so, but it is in Dutch.

A person can always use google translate or some similar program for the time

being

> Bb prophage, in short:

Very interesting. I look forward to reading your article!!

> I'm offically 'treated' as far as Lyme is concerned (I had way more than two

weeks, so they are done with me).

Wow, your situation is really bad. Talk about being stuck between a rock and a

hard place....so I guess I shouldn't push to have LD recognized here cuz it

obviously isn't any help at all, just more reason to kick us to the curb!!

Take Care,

Chris

[Guest guest]

My new article about lyme treatment with antibiotics, quorum sensing and

bacteriophages is now online. Still in Dutch, so you have to guess what it is

saying by using Google translate, or just enjoy the cartoons

'Antibiotica en Esperanto' (= Antibiotics and Esperanto):

http://www.lymevereniging.nl/file.php?id=192

This links to a PDF file, size about 1.3 MB.

English version at a later time maybe, but don't hold your breath ...

[Guest guest]

This is a great article; I was going to give a scanned copy to my doc; a pdf is

much easier; besides the pdf has the cartoons in colour!.

Thanks!

>

>

> My new article about lyme treatment with antibiotics, quorum sensing and

bacteriophages is now online. Still in Dutch, so you have to guess what it is

saying by using Google translate, or just enjoy the cartoons

>

> 'Antibiotica en Esperanto' (= Antibiotics and Esperanto):

> http://www.lymevereniging.nl/file.php?id=192

> This links to a PDF file, size about 1.3 MB.

>

> English version at a later time maybe, but don't hold your breath ...

>

[Guest guest]

>

> This is a great article; I was going to give a scanned copy to my doc; a pdf

is much easier; besides the pdf has the cartoons in colour!.

thanks; please spread

[Guest guest]

> >

> > This is a great article; I was going to give a scanned copy to my doc; a pdf

is much easier; besides the pdf has the cartoons in colour!.

>

> thanks; please spread

Actually, I just did ;-)

http://www.lymenet.nl/forum/viewtopic.php?f=4 & t=5976 & start=70#p58748

But I feel you should really try to get it translated/translate it yourself,

it's absolutely worthwhile

>

[Guest guest]

> But I feel you should really try to get it translated/translate it yourself,

it's absolutely worthwhile

maybe, I'm currently spending most of my time battling our ignorant CDC, and

there is a third LD article in the works. But I will check what the status is

for translating the article to english/german.