Guest guest Posted June 22, 2008 Report Share Posted June 22, 2008 I am wondering WHY you are asking about only two (2) days for IV when the post below states 14 days of IV? Jim. ### > > Why can't they do this treatment for those of us with Bartonella? > > *31* > TI Randomized open trial of gentamicin and doxycycline for eradication > of Bartonella quintana from blood in patients with chronic bacteremia. > AU Foucault C; Raoult D; Brouqui P > SO Antimicrob Agents Chemother 2003 Jul;47(7):2204- 7. > > Chronic Bartonella quintana bacteremia is known to occur in homeless > people exposed to lice. We present here the results of an open > randomized trial performed to evaluate the efficacy of doxycycline in > combination with gentamicin in the eradication of B. quintana > bacteremia. From 1 January 2001 to 1 April 2002, homeless people with > blood cultures positive for B. quintana were randomized to receive > either no treatment (untreated controls) or a combination of gentamicin > (3 mg/kg of body weight/day intravenously for 14 days) and doxycycline > (200 mg/day orally for 28 days). Patients were evaluated from the > results of blood cultures performed between day 28 (the end of > treatment) and day 90 postinclusion. Intention-to- treat analysis of 20 > included patients showed eradication of bacteremia in 7 out of 9 treated > patients versus 2 out of 11 untreated controls (P = 0.01). In the > per-protocol analysis, eradication was obtained for 7 out of 7 treated > patients versus 2 out of 9 untreated controls (P = 0.003). This study > demonstrates the efficiency of the combination of doxycycline and > gentamicin in eradicating B. quintana bacteremia. > > AD Unite des Rickettsies, CNRS UMR 6020, IFR48, Faculte de Medecine, > Universite de la Mediterranee, 13385 Marseille Cedex 05, France. > PMID 12821469 > > Cathleen > Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 23, 2008 Report Share Posted June 23, 2008 ok, I misread the number of days - gent for 14 days and doxy for 28 - but don't miss my point - they are curing this homeless person of bartonella, saving his life with an intensive but short treatment as opposed to the long oral treatment. I'm asking the question: which would be better? a short intesive IV treatment or a long oral treatment? cathleen JimBoB wrote: > > I am wondering WHY you are asking about only two (2) days for IV when > the post below states 14 days of IV? > > Jim. Quote Link to comment Share on other sites More sharing options...
Guest guest Posted June 25, 2008 Report Share Posted June 25, 2008 I think I would question the word " cure " here. In their tests, did they come back a year or two later to do a follow up test or not? The bart hides in cells, and THAT is the main reason it is almost impossible to really " CURE " . I would think the IV/doxy would be good ALONG with BUhner's recommendations, then the LONG oral, after a short break, pulsing it along with Buhner's protocol. Maybe. then in time, you could " cure " it. Jim. ### > > I am wondering WHY you are asking about only two (2) days for IV when > the post below states 14 days of IV? > > Jim. Quote Link to comment Share on other sites More sharing options...
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